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The map label for this gene is RsbU [H]

Identifier: 20808760

GI number: 20808760

Start: 2285220

End: 2287577

Strand: Reverse

Name: RsbU [H]

Synonym: TTE2396

Alternate gene names: 20808760

Gene position: 2287577-2285220 (Counterclockwise)

Preceding gene: 20808761

Following gene: 20808759

Centisome position: 85.06

GC content: 37.83

Gene sequence:

>2358_bases
ATGCAAAGCGCAAATGTGTTTCCTTACAAGAAAACTTTGAAAGGAAAGCTAAGTGAAAATGTCGACAAGGGTTTTTATAA
AAATGTTTTAAATTCAGTTTTGTTTTTGATTTTTGCTTTTATACTAGGAAGAGCTTCCATTTCCTATGTGCTTTTTCCTT
TTGGGATAGCTTTTTTTGCGGCATTAGTCGCTTACAAGAAAAAGTATTTCTTTGTAGGTCTAGGGGTGTGGCTGGCGTTA
TTGACAGTGCCAGGAGTAAATAGTGCTAAGTATCTTCTCAGCATGGCTATAATTTTTCTATTGGAACTTTTTTTGAGGGT
TAGGCCTACTAATGCTTTAAAGGCTTCTTTTATCACTCTTTTTTCTCTTTTCGCTTCAGGGCTGATTTTTAGCTATTCAT
ACAATTTTTTATATTTTGATGTTTTTTTAAGTTCATGTGAGGCAGTTATTGCGATGTTATTAGTTTTTATTTTTAACCAC
TCTCTTTCTTTCATTGTCAACAGAAGCACAAGGAAAGTAATTTCCAACGAAGAATTGGTTTCTTTAGGGATATTTACTGC
AGTTTTTATACTGGGGCTTCACAATTTAAGCATTTGGAAATTTAGTTTAAATAGTATAGCAATAGCCTTTGCGGTGCTTT
TTATAAGCTATCTGGGAGGCAGTGGGGCTGGTTCTGCGATAGGGACGACTATAGGGGTATTGAATGTGCTTGCATATGCG
GAAGCGCCTTCAATTGTAGGTGTTTTAGCTTTTGGAGGGCTTTTGGGAGGGAGTTTTCGCAAACTGCACAGGATTGGGAC
TATTGCAGGTTTTGTAATAGGAGCGGCAATAGTAGCTTTTTATACAGGGTTTAAAGTCGGCAATAGTTTAAACCCTTATG
GCATTGGATTGGCGGCTTTGCTCTTTGCAGCTTTTCCGAAGAAGTATATTCAAGAAGCTGAAAAATTGATTAAAGGAAAT
AAAAACTTAAATGACAGAGATTACAGCAGAAAATTAAAGGAAATAATTGCAGCAAAACTGAAAGAGTACTCGGGAGTTTT
TGAGGAACTTTCTAAGACCTTTAAGCAGTCAAATGAAAAAATACTGGACCATAAAGATATTTCCTATTTGTTTGAGGAAA
TTGCCAATAAGACCTGTTCTCAATGTGTTATGTATAAAAACTGCTGGGACAGAGATTTTTACAGCACTTATAAATCTATG
TTTGAACTAGTGGAGCATTTAGAGAAGGGGAAAGATATAAATGATAATAGGCTTTATAGGAAGTGCATTAGATTTTCTGA
GCTCATGTCAACTACTAAATATTATCTTGGAATCTATAAAATAAGCATGCAGTGGAGAGAGAGGCTAAAGGATGCAAAAG
GACTTATTGCGGCTCAGCTCAAAGGTGTTGCTGATGCTATTTCTGACATTGCAAAGGAGGTAAACATGAACATATCCTTT
AAAGATGAGCTGGAACAGGTCATTCTATTGGAGTTAGATAAAAATGGGATACAGGTGGAAGATGTTCTGGTGTACGAAAC
AGATGGTGGAAGCACAAGCGTAAAAGTGTACAGAGAAGAGGGGTATTTGTCAAAGGATTTGGAGAAAAAGATTGCCTCTG
TAATATCAGAAGTAATGGGAGAAAGGTATGAAAGGAAAGATAGACTTTACGGGATAGATTCTAAGGGAAGATGCGTTCTT
TCTTTTGCCAAGGCAGAAAGCTTGCAGGTCATCACTGGGGTTAGCAAAGTGAGCAAGGCGAAAAACAGGATTTCGGGGGA
TACCTACTCTTTTATGGACCTTAACAATGGAAAATATGTGGTGGCTTTAAGTGATGGCATGGGAGTTGGATACAAAGCCG
CAGCAGAAAGCACAACCGCCATTTCACTTTTGGAGAAGTTTATAGAAGCGGGGTTTGACAGGGAACTTGTCATCCAGACT
TTAAATTCCATTCTAGCCTTGCGGTCAGCTGAAGAGATGTTTTCCACTGTGGACATCATGTTTTTAGATAAGTTCACTGG
AAAAGCTGAGTTTATAAAGATTGGAGCTTGTGCCAGCTATGTAAAGAGAGGAACTTCAGTAGAGGTTATAAAGTCCAGTT
CGCTTCCCATAGGAATTCTCGAAGACATTGAGGCAGACCTTCATGAAAAGAAGTTAAAAGAAGGAGATTTTGTGATATTG
GTTACGGATGGGGTGCTGGAGTGCTTTGAGGGAGAAAAGGAGATGGAGCTTTTGAGGGTAATAAGCGAAGCAGATTTTAT
AAGTCCCCAGGAGATGGCGGATTATATAATGAAAAAATCTTTAGAAAGGTGTGAAAATACACCTAAAGACGACATGACAG
TGATAGTGGCAAAAATTTGGAAGAAGATTTATGTTTGA

Upstream 100 bases:

>100_bases
TTTTTTATGTCGAAAACAAAAATAAGTGAGATACAAAAAATAGCAAATAAATCCACCACCTTTATGGTATAATTTAGAAA
AAATAGAAGGTGGTGGAGGT

Downstream 100 bases:

>100_bases
TTTAAAGCGAGCTATAGTATATAATCATAGTATAGCGTGACTATGAGTTTTCAGAGGTTTGGTATGATTGAGAAGGTTTT
AAGGACCATTGAGAAGTACA

Product: Serine phosphatase RsbU, regulator of sigma subunit

Products: NA

Alternate protein names: Stage II sporulation protein H [H]

Number of amino acids: Translated: 785; Mature: 785

Protein sequence:

>785_residues
MQSANVFPYKKTLKGKLSENVDKGFYKNVLNSVLFLIFAFILGRASISYVLFPFGIAFFAALVAYKKKYFFVGLGVWLAL
LTVPGVNSAKYLLSMAIIFLLELFLRVRPTNALKASFITLFSLFASGLIFSYSYNFLYFDVFLSSCEAVIAMLLVFIFNH
SLSFIVNRSTRKVISNEELVSLGIFTAVFILGLHNLSIWKFSLNSIAIAFAVLFISYLGGSGAGSAIGTTIGVLNVLAYA
EAPSIVGVLAFGGLLGGSFRKLHRIGTIAGFVIGAAIVAFYTGFKVGNSLNPYGIGLAALLFAAFPKKYIQEAEKLIKGN
KNLNDRDYSRKLKEIIAAKLKEYSGVFEELSKTFKQSNEKILDHKDISYLFEEIANKTCSQCVMYKNCWDRDFYSTYKSM
FELVEHLEKGKDINDNRLYRKCIRFSELMSTTKYYLGIYKISMQWRERLKDAKGLIAAQLKGVADAISDIAKEVNMNISF
KDELEQVILLELDKNGIQVEDVLVYETDGGSTSVKVYREEGYLSKDLEKKIASVISEVMGERYERKDRLYGIDSKGRCVL
SFAKAESLQVITGVSKVSKAKNRISGDTYSFMDLNNGKYVVALSDGMGVGYKAAAESTTAISLLEKFIEAGFDRELVIQT
LNSILALRSAEEMFSTVDIMFLDKFTGKAEFIKIGACASYVKRGTSVEVIKSSSLPIGILEDIEADLHEKKLKEGDFVIL
VTDGVLECFEGEKEMELLRVISEADFISPQEMADYIMKKSLERCENTPKDDMTVIVAKIWKKIYV

Sequences:

>Translated_785_residues
MQSANVFPYKKTLKGKLSENVDKGFYKNVLNSVLFLIFAFILGRASISYVLFPFGIAFFAALVAYKKKYFFVGLGVWLAL
LTVPGVNSAKYLLSMAIIFLLELFLRVRPTNALKASFITLFSLFASGLIFSYSYNFLYFDVFLSSCEAVIAMLLVFIFNH
SLSFIVNRSTRKVISNEELVSLGIFTAVFILGLHNLSIWKFSLNSIAIAFAVLFISYLGGSGAGSAIGTTIGVLNVLAYA
EAPSIVGVLAFGGLLGGSFRKLHRIGTIAGFVIGAAIVAFYTGFKVGNSLNPYGIGLAALLFAAFPKKYIQEAEKLIKGN
KNLNDRDYSRKLKEIIAAKLKEYSGVFEELSKTFKQSNEKILDHKDISYLFEEIANKTCSQCVMYKNCWDRDFYSTYKSM
FELVEHLEKGKDINDNRLYRKCIRFSELMSTTKYYLGIYKISMQWRERLKDAKGLIAAQLKGVADAISDIAKEVNMNISF
KDELEQVILLELDKNGIQVEDVLVYETDGGSTSVKVYREEGYLSKDLEKKIASVISEVMGERYERKDRLYGIDSKGRCVL
SFAKAESLQVITGVSKVSKAKNRISGDTYSFMDLNNGKYVVALSDGMGVGYKAAAESTTAISLLEKFIEAGFDRELVIQT
LNSILALRSAEEMFSTVDIMFLDKFTGKAEFIKIGACASYVKRGTSVEVIKSSSLPIGILEDIEADLHEKKLKEGDFVIL
VTDGVLECFEGEKEMELLRVISEADFISPQEMADYIMKKSLERCENTPKDDMTVIVAKIWKKIYV
>Mature_785_residues
MQSANVFPYKKTLKGKLSENVDKGFYKNVLNSVLFLIFAFILGRASISYVLFPFGIAFFAALVAYKKKYFFVGLGVWLAL
LTVPGVNSAKYLLSMAIIFLLELFLRVRPTNALKASFITLFSLFASGLIFSYSYNFLYFDVFLSSCEAVIAMLLVFIFNH
SLSFIVNRSTRKVISNEELVSLGIFTAVFILGLHNLSIWKFSLNSIAIAFAVLFISYLGGSGAGSAIGTTIGVLNVLAYA
EAPSIVGVLAFGGLLGGSFRKLHRIGTIAGFVIGAAIVAFYTGFKVGNSLNPYGIGLAALLFAAFPKKYIQEAEKLIKGN
KNLNDRDYSRKLKEIIAAKLKEYSGVFEELSKTFKQSNEKILDHKDISYLFEEIANKTCSQCVMYKNCWDRDFYSTYKSM
FELVEHLEKGKDINDNRLYRKCIRFSELMSTTKYYLGIYKISMQWRERLKDAKGLIAAQLKGVADAISDIAKEVNMNISF
KDELEQVILLELDKNGIQVEDVLVYETDGGSTSVKVYREEGYLSKDLEKKIASVISEVMGERYERKDRLYGIDSKGRCVL
SFAKAESLQVITGVSKVSKAKNRISGDTYSFMDLNNGKYVVALSDGMGVGYKAAAESTTAISLLEKFIEAGFDRELVIQT
LNSILALRSAEEMFSTVDIMFLDKFTGKAEFIKIGACASYVKRGTSVEVIKSSSLPIGILEDIEADLHEKKLKEGDFVIL
VTDGVLECFEGEKEMELLRVISEADFISPQEMADYIMKKSLERCENTPKDDMTVIVAKIWKKIYV

Specific function: Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates spoIIAA by dephosphorylation [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Polar septum [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001932
- InterPro:   IPR014221
- InterPro:   IPR010822 [H]

Pfam domain/function: PF07228 SpoIIE [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 87665; Mature: 87665

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCC
>Mature Secondary Structure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HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8830262; 9384377; 2832371; 8113187; 7570023 [H]