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The map label for this gene is SpoU2 [H]

Identifier: 20808679

GI number: 20808679

Start: 2194454

End: 2195197

Strand: Reverse

Name: SpoU2 [H]

Synonym: TTE2313

Alternate gene names: 20808679

Gene position: 2195197-2194454 (Counterclockwise)

Preceding gene: 20808680

Following gene: 20808678

Centisome position: 81.62

GC content: 38.58

Gene sequence:

>744_bases
ATGAGAAATGGCGATATTATATATGGAAGAAACCCTGTTATAGAAGCGATAAGAAGCGGTAAGGAAATAGAAAAGATATA
CGTGTCCAAAACTGCCGGTGGCAATATTTCTAAAATAATAGGTATGGCGAAAGAAGCCGGAATTGTAGTTTCTACTGCTG
ACAGTGATACCTTGAAGAGGTTAGCGCAGACTCCTAATCATCAAGGAGTAGTTGCAGTTGGAGCTTTGTATAAATATTTT
GATGTGACGGATATTTTAAACTATGCAGAAGAGAAGAAAGAAAAGCCTTTTTTGTTGATTTTAGATGAGATAACTGACCC
TCACAATATGGGTGCTATAATAAGAAGTGCGGAAGCTTTTGGAGTGCACGGGGTGATAATTCCCAAAAGGCGTTCTGCAG
GGATAAATGCCACAGTGGTAAAGGCCTCAGCTGGTGCGGTAGAATACATAAAAGTGGCAAAAGTTTCAAATATTAACAGC
ACCATAAGGGATCTGAAAGAAAAAGGACTTTGGATTATTGGGACTGACGCAAAAGCTGAGAAGAGTTTTGAAGAGCTAGA
TTACGATTTTCCTCTGGCTCTGGTCATTGGAAGTGAGGGAAAAGGAATTTCGAGGTTGGTTTTAGAGAATTGTGATTTTG
TAATTAAAATTCCCATGAAGGGTAAAATCAATTCTCTTAACGCTTCTGTTGCTGCTTCTATTTTGATGTACAACATTTTA
TCAAAAAGGCAAGGTAAGGCGTGA

Upstream 100 bases:

>100_bases
TGAAGCATTAGTGGGATATTTGTACCTTTTAGAAAGATTTGATAGGCTTTACTTTCTTTTGAGCCTTTCTATGGAATACA
CGGAAGAATAGGTGAAAATT

Downstream 100 bases:

>100_bases
TGCCCTTGTATATGCTGGTAGACGGTTATAATGTCATAAACAACTGGCAGATGCTCAAGGAAATTGCAAAGAGAAGTCTG
GAAGATGCGAGAGACAAATT

Product: rRNA methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRNGDIIYGRNPVIEAIRSGKEIEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKRLAQTPNHQGVVAVGALYKYF
DVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAFGVHGVIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINS
TIRDLKEKGLWIIGTDAKAEKSFEELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNIL
SKRQGKA

Sequences:

>Translated_247_residues
MRNGDIIYGRNPVIEAIRSGKEIEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKRLAQTPNHQGVVAVGALYKYF
DVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAFGVHGVIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINS
TIRDLKEKGLWIIGTDAKAEKSFEELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNIL
SKRQGKA
>Mature_247_residues
MRNGDIIYGRNPVIEAIRSGKEIEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKRLAQTPNHQGVVAVGALYKYF
DVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAFGVHGVIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINS
TIRDLKEKGLWIIGTDAKAEKSFEELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNIL
SKRQGKA

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=260, Percent_Identity=27.3076923076923, Blast_Score=102, Evalue=3e-22,
Organism=Escherichia coli, GI1790623, Length=244, Percent_Identity=37.2950819672131, Blast_Score=171, Evalue=3e-44,
Organism=Escherichia coli, GI1790083, Length=170, Percent_Identity=31.1764705882353, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788935, Length=196, Percent_Identity=25.5102040816327, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=257, Percent_Identity=30.3501945525292, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324775, Length=173, Percent_Identity=34.1040462427746, Blast_Score=89, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26763; Mature: 26763

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNGDIIYGRNPVIEAIRSGKEIEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKR
CCCCCEEECCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCHHHHHH
LAQTPNHQGVVAVGALYKYFDVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAF
HHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
GVHGVIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINSTIRDLKEKGLWIIGTDAKAE
CEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEHHCCCHHHHHHHHHCCCEEEECCCHHH
KSFEELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNIL
HHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
SKRQGKA
HHCCCCC
>Mature Secondary Structure
MRNGDIIYGRNPVIEAIRSGKEIEKIYVSKTAGGNISKIIGMAKEAGIVVSTADSDTLKR
CCCCCEEECCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCHHHHHH
LAQTPNHQGVVAVGALYKYFDVTDILNYAEEKKEKPFLLILDEITDPHNMGAIIRSAEAF
HHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHC
GVHGVIIPKRRSAGINATVVKASAGAVEYIKVAKVSNINSTIRDLKEKGLWIIGTDAKAE
CEEEEEEECCCCCCCCEEEEEECCCCEEEEEEEHHCCCHHHHHHHHHCCCEEEECCCHHH
KSFEELDYDFPLALVIGSEGKGISRLVLENCDFVIKIPMKGKINSLNASVAASILMYNIL
HHHHHCCCCCCEEEEECCCCCCHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHH
SKRQGKA
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]