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The map label for this gene is buk2

Identifier: 20808585

GI number: 20808585

Start: 2114644

End: 2115708

Strand: Reverse

Name: buk2

Synonym: TTE2205

Alternate gene names: 20808585

Gene position: 2115708-2114644 (Counterclockwise)

Preceding gene: 20808586

Following gene: 20808584

Centisome position: 78.67

GC content: 42.16

Gene sequence:

>1065_bases
TTGTTCAAGGTATTGGTCATCAATCCAGGTTCTACTTCCACCAAAGTAGCTCTTTATGAAGACGAGAAGGAAATAGTGCG
TTCTGACATCACCCATGATGTAGAAACTCTCAAGAACTATAAAAGTGTGATTGAGCAGCTGGATTTGAGGTTAGAAGCGA
TAAACAAATGGCTAAGTGAGAATGGCATTAAAGTTCTGGAATTATCTGCTATTGTGGTGAGGGGTGGTTTGATAAAGCCA
GTCCAAAGTGGTACCTACGTTGTAAACGATATTATGCTGGAAGATTTAAGAAAAGGGGTAGGAGGGGAACATCCTTCAAA
TCTAGGCGGAATAATTGGAAGGGCTCTGGCAGACCCATACGGGATACCTGTTTATACTCTCGACCCTGTGGCAGTAGACG
AAATGGAAGATGTGGCGAGAATTTCAGGTCTCCCAGAGCTTCCCAGAAAGAGCCAATCTCATGCTCTAAACATTAAAGCC
TGCATACACAGGTATGCGAGGGAAAACAATTTAAAAGAAGAGGAACTTAATATGATTGTGGCTCACATGGGAGGAGGAAT
TTCTGTAGCAGCTATAAAGGGAGGTAGGATTGTTGATGTAAACAATGCAAATCAAATGGGGCCTTTTTCACCTGAGAGGA
CTGGAAGTTTGCCTTCCATGAAGGTCGTAGAGATGTGTTATTCAGGAAAATACACTTTGGAAGAGATGAAGAAAAAAATT
GTCGGAATGGGAGGACTCGTGGCGCATCTTGGTACCAACGATGCCAGAGAAGTGGTAAAAAGAATAGAAGCTGGGGATAA
AAAAGCTAAGCTAGTTTTTGAAGCTATGGCTTATCAGATTGCGAAAGAGATTGGCAGGATGGCTGCGGTGTTAAAAGGAG
ATGTTAAGACAATTATTTTAACTGGGGGGCTTGCTTATTCCAAACCCTTGATAGAGATAATAATTGACATGGTAGGCTTT
ATCGCTCCAATCACTTTATATCCCGGTGGAGACGAGATGGAGGCTTTAAGAGATGGAGCTTTAAGAGTGTTAAGAGGGCA
GGAAACTCCAAAAATTTATGGCTGA

Upstream 100 bases:

>100_bases
AAGAAGGATTTTTGACAAATGTGTAGAATTAAAATATTGTAAGGATAAAAATTTTTTAAGACACTCAAAAAATGTTTGGC
GAAAGGGCGGGTGAAGCCTG

Downstream 100 bases:

>100_bases
TGGGGTGTTGGTATGAGGACCTTTGCTGAACTTTACGAGCATGTGAAAAATTTGCCGCCAAAAGTTATAGCTGTGGCTCA
GGCAGCTGATGAAGATGTGT

Product: butyrate kinase

Products: NA

Alternate protein names: BK 2; Branched-chain carboxylic acid kinase 2

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MFKVLVINPGSTSTKVALYEDEKEIVRSDITHDVETLKNYKSVIEQLDLRLEAINKWLSENGIKVLELSAIVVRGGLIKP
VQSGTYVVNDIMLEDLRKGVGGEHPSNLGGIIGRALADPYGIPVYTLDPVAVDEMEDVARISGLPELPRKSQSHALNIKA
CIHRYARENNLKEEELNMIVAHMGGGISVAAIKGGRIVDVNNANQMGPFSPERTGSLPSMKVVEMCYSGKYTLEEMKKKI
VGMGGLVAHLGTNDAREVVKRIEAGDKKAKLVFEAMAYQIAKEIGRMAAVLKGDVKTIILTGGLAYSKPLIEIIIDMVGF
IAPITLYPGGDEMEALRDGALRVLRGQETPKIYG

Sequences:

>Translated_354_residues
MFKVLVINPGSTSTKVALYEDEKEIVRSDITHDVETLKNYKSVIEQLDLRLEAINKWLSENGIKVLELSAIVVRGGLIKP
VQSGTYVVNDIMLEDLRKGVGGEHPSNLGGIIGRALADPYGIPVYTLDPVAVDEMEDVARISGLPELPRKSQSHALNIKA
CIHRYARENNLKEEELNMIVAHMGGGISVAAIKGGRIVDVNNANQMGPFSPERTGSLPSMKVVEMCYSGKYTLEEMKKKI
VGMGGLVAHLGTNDAREVVKRIEAGDKKAKLVFEAMAYQIAKEIGRMAAVLKGDVKTIILTGGLAYSKPLIEIIIDMVGF
IAPITLYPGGDEMEALRDGALRVLRGQETPKIYG
>Mature_354_residues
MFKVLVINPGSTSTKVALYEDEKEIVRSDITHDVETLKNYKSVIEQLDLRLEAINKWLSENGIKVLELSAIVVRGGLIKP
VQSGTYVVNDIMLEDLRKGVGGEHPSNLGGIIGRALADPYGIPVYTLDPVAVDEMEDVARISGLPELPRKSQSHALNIKA
CIHRYARENNLKEEELNMIVAHMGGGISVAAIKGGRIVDVNNANQMGPFSPERTGSLPSMKVVEMCYSGKYTLEEMKKKI
VGMGGLVAHLGTNDAREVVKRIEAGDKKAKLVFEAMAYQIAKEIGRMAAVLKGDVKTIILTGGLAYSKPLIEIIIDMVGF
IAPITLYPGGDEMEALRDGALRVLRGQETPKIYG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BUK2_THETN (Q8R828)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623756.1
- ProteinModelPortal:   Q8R828
- SMR:   Q8R828
- GeneID:   997646
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE2205
- NMPDR:   fig|273068.3.peg.2389
- HOGENOM:   HBG449785
- OMA:   HRYAREN
- ProtClustDB:   PRK03011
- BioCyc:   TTEN273068:TTE2205-MONOMER
- BRENDA:   2.7.2.7
- GO:   GO:0005737
- HAMAP:   MF_00542
- InterPro:   IPR000890
- InterPro:   IPR011245
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF3
- PIRSF:   PIRSF036458
- PRINTS:   PR00471
- TIGRFAMs:   TIGR02707

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.7

Molecular weight: Translated: 38553; Mature: 38553

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKVLVINPGSTSTKVALYEDEKEIVRSDITHDVETLKNYKSVIEQLDLRLEAINKWLSE
CEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGIKVLELSAIVVRGGLIKPVQSGTYVVNDIMLEDLRKGVGGEHPSNLGGIIGRALADPY
CCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
GIPVYTLDPVAVDEMEDVARISGLPELPRKSQSHALNIKACIHRYARENNLKEEELNMIV
CCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHH
AHMGGGISVAAIKGGRIVDVNNANQMGPFSPERTGSLPSMKVVEMCYSGKYTLEEMKKKI
EECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHH
VGMGGLVAHLGTNDAREVVKRIEAGDKKAKLVFEAMAYQIAKEIGRMAAVLKGDVKTIIL
HCCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGGLAYSKPLIEIIIDMVGFIAPITLYPGGDEMEALRDGALRVLRGQETPKIYG
ECCCHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MFKVLVINPGSTSTKVALYEDEKEIVRSDITHDVETLKNYKSVIEQLDLRLEAINKWLSE
CEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NGIKVLELSAIVVRGGLIKPVQSGTYVVNDIMLEDLRKGVGGEHPSNLGGIIGRALADPY
CCCEEEEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
GIPVYTLDPVAVDEMEDVARISGLPELPRKSQSHALNIKACIHRYARENNLKEEELNMIV
CCCEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHH
AHMGGGISVAAIKGGRIVDVNNANQMGPFSPERTGSLPSMKVVEMCYSGKYTLEEMKKKI
EECCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHH
VGMGGLVAHLGTNDAREVVKRIEAGDKKAKLVFEAMAYQIAKEIGRMAAVLKGDVKTIIL
HCCCHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
TGGLAYSKPLIEIIIDMVGFIAPITLYPGGDEMEALRDGALRVLRGQETPKIYG
ECCCHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336