Click here to switch to the map view.

The map label for this gene is WecG [H]

Identifier: 20808547

GI number: 20808547

Start: 2083208

End: 2083942

Strand: Reverse

Name: WecG [H]

Synonym: TTE2163

Alternate gene names: 20808547

Gene position: 2083942-2083208 (Counterclockwise)

Preceding gene: 20808548

Following gene: 20808546

Centisome position: 77.49

GC content: 36.46

Gene sequence:

>735_bases
ATGGATAAGTTGTATATATTTGGAGTACCAATACATAGGGTTACAATGATCGAAGCAGTTGAAATTTTAAAAGGTTATCT
TAAAGAGGATAGGATTCACATAGTGGCAACTCCTAATGCAGAGATCATAATGATGGCTCAGAAGGACGAAGAGTATAAAA
AAATCTTGAATGAGACTGACCTTAATGTGCCAGATGGCAGTGGAGTAGTGTTTGCTTCAAGGGTCTTCAATAAGCCTTTA
AAAGAGAGGGTTGCTGGGTTTGACCTGATGATGGAATTTGTAAAATGGGCATCTCATAAAGATGTTTCGATATATCTTTT
AGGAGCAAAACCGGAAGTTGTTGAAAAAGCACAAAGTAATTTAAAAAATCTTTACCCTTCTCTTAAAATAGTTGGATTTC
ATCACGGTTATTTTAATGAAAAAGAAGAAGAAAACATCATTGAAGACATAAATAAAAGGGCTGCACAGGTGCTTTTTGTG
GCATTAGGAGCTCCTAAGCAGGAGAAGTGGATATATAAAAATAAGGAGAAGCTTAAAGTGAAGATAGCCATGGGGGTTGG
AGGAAGCTTTGATGTTATTGCAGGCAAAGCAAAAAGAGCACCAGAAATTTATAGAAAGCTTGGACTTGAGTGGCTATATC
GTCTGATACAAGAGCCCTGGCGCTATAAAAGGATGTCAGCACTTCCCAAATTTGCTTTTAAAGTGCTTTTAGCTAGATTA
AAAGGAGATTTTTAA

Upstream 100 bases:

>100_bases
CAGAGAAGATTACGTGAAAAAGATGGCTGATTATCTGGAGGAATTAAAGAAAAAAGCAGAAATGAATTTTGAAATACTGT
TTAAGTGAAGGTGTAATAAT

Downstream 100 bases:

>100_bases
GCAAAGGAGGTTCAAAACAGTTAAAATTAATAGTAAAAATGATACAATTTTAATTAGATGATAATAAAAGTTACTAACTA
TAAAAAAAGTTAAAGAGTTA

Product: teichoic acid biosynthesis proteins

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDKLYIFGVPIHRVTMIEAVEILKGYLKEDRIHIVATPNAEIIMMAQKDEEYKKILNETDLNVPDGSGVVFASRVFNKPL
KERVAGFDLMMEFVKWASHKDVSIYLLGAKPEVVEKAQSNLKNLYPSLKIVGFHHGYFNEKEEENIIEDINKRAAQVLFV
ALGAPKQEKWIYKNKEKLKVKIAMGVGGSFDVIAGKAKRAPEIYRKLGLEWLYRLIQEPWRYKRMSALPKFAFKVLLARL
KGDF

Sequences:

>Translated_244_residues
MDKLYIFGVPIHRVTMIEAVEILKGYLKEDRIHIVATPNAEIIMMAQKDEEYKKILNETDLNVPDGSGVVFASRVFNKPL
KERVAGFDLMMEFVKWASHKDVSIYLLGAKPEVVEKAQSNLKNLYPSLKIVGFHHGYFNEKEEENIIEDINKRAAQVLFV
ALGAPKQEKWIYKNKEKLKVKIAMGVGGSFDVIAGKAKRAPEIYRKLGLEWLYRLIQEPWRYKRMSALPKFAFKVLLARL
KGDF
>Mature_244_residues
MDKLYIFGVPIHRVTMIEAVEILKGYLKEDRIHIVATPNAEIIMMAQKDEEYKKILNETDLNVPDGSGVVFASRVFNKPL
KERVAGFDLMMEFVKWASHKDVSIYLLGAKPEVVEKAQSNLKNLYPSLKIVGFHHGYFNEKEEENIIEDINKRAAQVLFV
ALGAPKQEKWIYKNKEKLKVKIAMGVGGSFDVIAGKAKRAPEIYRKLGLEWLYRLIQEPWRYKRMSALPKFAFKVLLARL
KGDF

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=186, Percent_Identity=36.5591397849462, Blast_Score=128, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 28087; Mature: 28087

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLYIFGVPIHRVTMIEAVEILKGYLKEDRIHIVATPNAEIIMMAQKDEEYKKILNETD
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHHHHHHCC
LNVPDGSGVVFASRVFNKPLKERVAGFDLMMEFVKWASHKDVSIYLLGAKPEVVEKAQSN
CCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
LKNLYPSLKIVGFHHGYFNEKEEENIIEDINKRAAQVLFVALGAPKQEKWIYKNKEKLKV
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
KIAMGVGGSFDVIAGKAKRAPEIYRKLGLEWLYRLIQEPWRYKRMSALPKFAFKVLLARL
EEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGDF
CCCC
>Mature Secondary Structure
MDKLYIFGVPIHRVTMIEAVEILKGYLKEDRIHIVATPNAEIIMMAQKDEEYKKILNETD
CCCEEEEECCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHHHHHHCC
LNVPDGSGVVFASRVFNKPLKERVAGFDLMMEFVKWASHKDVSIYLLGAKPEVVEKAQSN
CCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHH
LKNLYPSLKIVGFHHGYFNEKEEENIIEDINKRAAQVLFVALGAPKQEKWIYKNKEKLKV
HHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEE
KIAMGVGGSFDVIAGKAKRAPEIYRKLGLEWLYRLIQEPWRYKRMSALPKFAFKVLLARL
EEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGDF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]