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The map label for this gene is KdpD2 [H]

Identifier: 20808542

GI number: 20808542

Start: 2077078

End: 2078220

Strand: Direct

Name: KdpD2 [H]

Synonym: TTE2155

Alternate gene names: 20808542

Gene position: 2077078-2078220 (Clockwise)

Preceding gene: 20808541

Following gene: 20808543

Centisome position: 77.23

GC content: 37.36

Gene sequence:

>1143_bases
ATGAGTGGAGGTTATAGGAGGCTTACTCCTGAAGAAGCCTTGGAAATTGTAAAAAAAGAGCAAAGAGGAAAACTGAAAAT
ATTCTTGGGATACGCTCCTGGCGTTGGAAAAACTTATGCTATGTTAAACGAAGGAAATAGGCGTCTCAAAAGGGGGCAGG
ATGTCGTAATAGGCTATGTAGAAACCCATGGAAGAAAGGACACAGAAGCTCAAATAGGAAATTTAGAAATAATACCTCGG
AAAAAAATTGAATATCACGGTATGATATTGGAAGAAATGGACGTAGATGCTATAATAGCACGAAAACCCGAAGTAGTTCT
AATTGACGAGCTAGCCCATACCAACGCTCCTGGTTCAAAACACAAAAAGAGGTATGAGGATGTCCAAGAAATTCTGGAAC
ACGGAATAAACGTGCTCACTACCCTAAATATACAGCATATAGAAAGCTTAAACGATATAATTCAGCAGATCACAGGAATA
GCAGTAAGAGAAACAGTACCTGACAGCATAATAGATAACGCAGATGAAATTGTAGCAGTAGATTTAACTCCAGATGCTCT
GATAAACAGACTAAAAAGAGGGGATGTATACCCCTTAAGTAAACTGGATGAATGTCTTTCTAATTTTTTCAGAAAAGGCA
ATTTAAGTGCTTTAAGAGAATTAATGTTAAGACTCACCGCTGAAGAAGTAGACCTGGAGTTAGAAGAATACATGAAAGAG
CACGGAATAGAGGATACATGGGAAACAAATGAGAAAATAATGGTATGCATAACGCCAAATCCTCTATCTAAAAAACTCAT
ACGAAGAGGTGCAAGAAGGGCGAGAAGATTTAAGTGTGACTGGGTTGTCGTATACGTGGACTGCACTCATTTTTTGGCAC
CAAAACTTACTGAAAAAGACAAAGAAGTTTTAGAAAGTCATTTTATGCTCGCAAAGCAATTAGGTGCAGAAGTTTATACC
TTAAGAGGAAAGAGCGTCTCCGATGAACTTTTGAAGTTTGCTAAAAAAATGCACATAACCCAAATAATAATCGGACACTC
TCAGAGGTCATGGCTTCAGACCTTGTTTAGAGGCTCTACTGTAATAAAATTGATTAAAAAAGCTAAAAATATCGAGATAC
ACGTAATTCCTTACACAAAATAA

Upstream 100 bases:

>100_bases
GGGAGCAGTTGCTCCCTATTTTTGTTGATTTTTTGTGAAAATGTGATTATAATTTTATGCAGTTACTCTAAGTAAAATTC
TTGGAGGGTGTTTATTCTTA

Downstream 100 bases:

>100_bases
AAGCTCAAGGGGTAATGAAAAATGCAGAACAAATTTGGATTTTCCCTTTCAATTTTTCTGTTCACATTAATTCTCACCAT
GACAATGGTTCTATTTTTCC

Product: osmosensitive K+ channel histidine kinase sensor subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSGGYRRLTPEEALEIVKKEQRGKLKIFLGYAPGVGKTYAMLNEGNRRLKRGQDVVIGYVETHGRKDTEAQIGNLEIIPR
KKIEYHGMILEEMDVDAIIARKPEVVLIDELAHTNAPGSKHKKRYEDVQEILEHGINVLTTLNIQHIESLNDIIQQITGI
AVRETVPDSIIDNADEIVAVDLTPDALINRLKRGDVYPLSKLDECLSNFFRKGNLSALRELMLRLTAEEVDLELEEYMKE
HGIEDTWETNEKIMVCITPNPLSKKLIRRGARRARRFKCDWVVVYVDCTHFLAPKLTEKDKEVLESHFMLAKQLGAEVYT
LRGKSVSDELLKFAKKMHITQIIIGHSQRSWLQTLFRGSTVIKLIKKAKNIEIHVIPYTK

Sequences:

>Translated_380_residues
MSGGYRRLTPEEALEIVKKEQRGKLKIFLGYAPGVGKTYAMLNEGNRRLKRGQDVVIGYVETHGRKDTEAQIGNLEIIPR
KKIEYHGMILEEMDVDAIIARKPEVVLIDELAHTNAPGSKHKKRYEDVQEILEHGINVLTTLNIQHIESLNDIIQQITGI
AVRETVPDSIIDNADEIVAVDLTPDALINRLKRGDVYPLSKLDECLSNFFRKGNLSALRELMLRLTAEEVDLELEEYMKE
HGIEDTWETNEKIMVCITPNPLSKKLIRRGARRARRFKCDWVVVYVDCTHFLAPKLTEKDKEVLESHFMLAKQLGAEVYT
LRGKSVSDELLKFAKKMHITQIIIGHSQRSWLQTLFRGSTVIKLIKKAKNIEIHVIPYTK
>Mature_379_residues
SGGYRRLTPEEALEIVKKEQRGKLKIFLGYAPGVGKTYAMLNEGNRRLKRGQDVVIGYVETHGRKDTEAQIGNLEIIPRK
KIEYHGMILEEMDVDAIIARKPEVVLIDELAHTNAPGSKHKKRYEDVQEILEHGINVLTTLNIQHIESLNDIIQQITGIA
VRETVPDSIIDNADEIVAVDLTPDALINRLKRGDVYPLSKLDECLSNFFRKGNLSALRELMLRLTAEEVDLELEEYMKEH
GIEDTWETNEKIMVCITPNPLSKKLIRRGARRARRFKCDWVVVYVDCTHFLAPKLTEKDKEVLESHFMLAKQLGAEVYTL
RGKSVSDELLKFAKKMHITQIIIGHSQRSWLQTLFRGSTVIKLIKKAKNIEIHVIPYTK

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=352, Percent_Identity=46.0227272727273, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43498; Mature: 43367

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGYRRLTPEEALEIVKKEQRGKLKIFLGYAPGVGKTYAMLNEGNRRLKRGQDVVIGYV
CCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCHHHHCCCCEEEEEE
ETHGRKDTEAQIGNLEIIPRKKIEYHGMILEEMDVDAIIARKPEVVLIDELAHTNAPGSK
ECCCCCCCCCCCCCEEEEECCCHHHCCEEHHHCCCCHHEECCCCEEEEECHHCCCCCCHH
HKKRYEDVQEILEHGINVLTTLNIQHIESLNDIIQQITGIAVRETVPDSIIDNADEIVAV
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCEEEE
DLTPDALINRLKRGDVYPLSKLDECLSNFFRKGNLSALRELMLRLTAEEVDLELEEYMKE
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
HGIEDTWETNEKIMVCITPNPLSKKLIRRGARRARRFKCDWVVVYVDCTHFLAPKLTEKD
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCCHHH
KEVLESHFMLAKQLGAEVYTLRGKSVSDELLKFAKKMHITQIIIGHSQRSWLQTLFRGST
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCHH
VIKLIKKAKNIEIHVIPYTK
HHHHHHHHCCCEEEEEECCC
>Mature Secondary Structure 
SGGYRRLTPEEALEIVKKEQRGKLKIFLGYAPGVGKTYAMLNEGNRRLKRGQDVVIGYV
CCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCHHHHCCCCEEEEEE
ETHGRKDTEAQIGNLEIIPRKKIEYHGMILEEMDVDAIIARKPEVVLIDELAHTNAPGSK
ECCCCCCCCCCCCCEEEEECCCHHHCCEEHHHCCCCHHEECCCCEEEEECHHCCCCCCHH
HKKRYEDVQEILEHGINVLTTLNIQHIESLNDIIQQITGIAVRETVPDSIIDNADEIVAV
HHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCEEEE
DLTPDALINRLKRGDVYPLSKLDECLSNFFRKGNLSALRELMLRLTAEEVDLELEEYMKE
ECCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHH
HGIEDTWETNEKIMVCITPNPLSKKLIRRGARRARRFKCDWVVVYVDCTHFLAPKLTEKD
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHCCCCCHHH
KEVLESHFMLAKQLGAEVYTLRGKSVSDELLKFAKKMHITQIIIGHSQRSWLQTLFRGST
HHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHEECCCHHHHHHHHHCCHH
VIKLIKKAKNIEIHVIPYTK
HHHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]