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The map label for this gene is Sun2 [H]

Identifier: 20808537

GI number: 20808537

Start: 2070154

End: 2071536

Strand: Reverse

Name: Sun2 [H]

Synonym: TTE2147

Alternate gene names: 20808537

Gene position: 2071536-2070154 (Counterclockwise)

Preceding gene: 20808538

Following gene: 20808536

Centisome position: 77.02

GC content: 38.68

Gene sequence:

>1383_bases
ATGAAAGTACCGGTCAAAGAAGAGTTTTTAAAGAGGATGAAGGAGCTTTTAAAGGAAGAGTACGAAGCCTTTTTGAAGGA
GTATGAGAAAAAGCCTCAAAAGGGATTGAGAGTAAATACTTTGAAAATTGATGTGGAAAATTTTAAAAAAATTGCGCCTT
TTGAGATAGAACCCATTCCGTGGTGTCCAACAGGGTTTTACTATGAAAAAGAAGAAAAAGCAGGGAATCACTTGTACCAT
GTGTTAGGACTTTATTACATACAAGAGCCTACGGCAATGGCTGTAGTGGAGGTATTAGATCCCAAGCCTGGTGAGAAAAT
TTTGGATGTGAGCGCTGCCCCGGGAGGAAAGACTACTCACATTGCATCTAAAATTGGGGATGAAGGCCTTATTGTGGCAA
ATGAGATAGATAGAAAGAGGATAAGGGCTTTAGAAGAAAATGTGGCTAGAATGGGAATAAGAAATATAGTTCTCTTAAAT
GAAAGGCCGGAGAGGTTAATTCAAGCTTTTGAAGGGTATTTTGACAAAATAGTAGTAGATGCGCCTTGTTCTGGAGAGGG
AATGTTTAGAAAAGACCCTGCTGCTAGGAGAATATGGTCTTTAAATAATGTATTGAGCTGTTCTATAACTCAGAGAAATA
TCTTGAGAAGCGTAGCACCTTTGCTTAAAAGAGGGGGGGTATTGGTATATTCTACCTGCACTTTTTCGCCGGAAGAAAAC
GAAGGGGTCATAAAGAAGTTTTTAGAAGAAAACCCGGAATTTGAGGTAGTAGAAAGCGAGTTAAGTCACTTTTTTGATAA
AGGGCATCCCGAGTGGGTGGACGGCCCTAAAGAACTTGAAAAATGCATGAGGCTATGGCCTCACAAGGTAAGGGGAGAGG
GACATTTCATCGCAAAGCTCAAAAAGAATGGAGAAGATGTGAATGTAAATTTTAAGAGAAAAGTTGAGAAAAAGAAACAT
CAAAAAGAATTAGAGCTTTTTTATCAGTTTGCAGATAAATATCTCGATTTAGATTTGGAGATACTAAATCTTCAAGTAGA
CAATAACTTTGTGTATCATGTGCCTTTGGATCTGCCGGAATTAAAAGGCATAAGGATTTACAGGCATGGCTGGCTTATGG
GAGAGCTCAAAAAAAATCGATTTGAACCTTCTCACTGGTTGGCTATGGGATTAAAGCCAAGCCAGATTAAAAGGGTATTA
GAGCTTGACAAATTTCAGAGAGAAAAATATCTAAATGGAGAGACCTTTGAACTTGACGAAGAAGATGGATGGATACTTTT
TACAGCAGAAAATTTCCCAGCTGGCTGGGGCAGAGTTGCAAAGGGAGTAGTTAAAAATTATTTTCCGAAATGGCTAAGAG
ATATAGAAGTATGGGAGGAATGA

Upstream 100 bases:

>100_bases
TGAAGAGGCTTATAAAGACCAAGTTGTACTGGATAAAATAATTTTATCTGCTGAAAATAATGGTGAAACTATAAAGTTTT
AAAAATAGGGGTAATAAGAG

Downstream 100 bases:

>100_bases
AAAGCCCTACTAAAGGGGCTTTTATTTTTTGCTTTAAAAAGTTAATTTTGGGGGAATAATATTTTTAGCATAAAAACTGC
GATGTAGGAGGAGTTGACGG

Product: tRNA and rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: 16S rRNA m5C1407 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmF [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKVPVKEEFLKRMKELLKEEYEAFLKEYEKKPQKGLRVNTLKIDVENFKKIAPFEIEPIPWCPTGFYYEKEEKAGNHLYH
VLGLYYIQEPTAMAVVEVLDPKPGEKILDVSAAPGGKTTHIASKIGDEGLIVANEIDRKRIRALEENVARMGIRNIVLLN
ERPERLIQAFEGYFDKIVVDAPCSGEGMFRKDPAARRIWSLNNVLSCSITQRNILRSVAPLLKRGGVLVYSTCTFSPEEN
EGVIKKFLEENPEFEVVESELSHFFDKGHPEWVDGPKELEKCMRLWPHKVRGEGHFIAKLKKNGEDVNVNFKRKVEKKKH
QKELELFYQFADKYLDLDLEILNLQVDNNFVYHVPLDLPELKGIRIYRHGWLMGELKKNRFEPSHWLAMGLKPSQIKRVL
ELDKFQREKYLNGETFELDEEDGWILFTAENFPAGWGRVAKGVVKNYFPKWLRDIEVWEE

Sequences:

>Translated_460_residues
MKVPVKEEFLKRMKELLKEEYEAFLKEYEKKPQKGLRVNTLKIDVENFKKIAPFEIEPIPWCPTGFYYEKEEKAGNHLYH
VLGLYYIQEPTAMAVVEVLDPKPGEKILDVSAAPGGKTTHIASKIGDEGLIVANEIDRKRIRALEENVARMGIRNIVLLN
ERPERLIQAFEGYFDKIVVDAPCSGEGMFRKDPAARRIWSLNNVLSCSITQRNILRSVAPLLKRGGVLVYSTCTFSPEEN
EGVIKKFLEENPEFEVVESELSHFFDKGHPEWVDGPKELEKCMRLWPHKVRGEGHFIAKLKKNGEDVNVNFKRKVEKKKH
QKELELFYQFADKYLDLDLEILNLQVDNNFVYHVPLDLPELKGIRIYRHGWLMGELKKNRFEPSHWLAMGLKPSQIKRVL
ELDKFQREKYLNGETFELDEEDGWILFTAENFPAGWGRVAKGVVKNYFPKWLRDIEVWEE
>Mature_460_residues
MKVPVKEEFLKRMKELLKEEYEAFLKEYEKKPQKGLRVNTLKIDVENFKKIAPFEIEPIPWCPTGFYYEKEEKAGNHLYH
VLGLYYIQEPTAMAVVEVLDPKPGEKILDVSAAPGGKTTHIASKIGDEGLIVANEIDRKRIRALEENVARMGIRNIVLLN
ERPERLIQAFEGYFDKIVVDAPCSGEGMFRKDPAARRIWSLNNVLSCSITQRNILRSVAPLLKRGGVLVYSTCTFSPEEN
EGVIKKFLEENPEFEVVESELSHFFDKGHPEWVDGPKELEKCMRLWPHKVRGEGHFIAKLKKNGEDVNVNFKRKVEKKKH
QKELELFYQFADKYLDLDLEILNLQVDNNFVYHVPLDLPELKGIRIYRHGWLMGELKKNRFEPSHWLAMGLKPSQIKRVL
ELDKFQREKYLNGETFELDEEDGWILFTAENFPAGWGRVAKGVVKNYFPKWLRDIEVWEE

Specific function: Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=285, Percent_Identity=31.9298245614035, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI76150623, Length=285, Percent_Identity=31.9298245614035, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI32698918, Length=170, Percent_Identity=39.4117647058824, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI39995082, Length=269, Percent_Identity=30.4832713754647, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI301336155, Length=269, Percent_Identity=30.4832713754647, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI8922322, Length=254, Percent_Identity=27.1653543307087, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI270288818, Length=254, Percent_Identity=27.1653543307087, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI23199998, Length=254, Percent_Identity=27.1653543307087, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI270288816, Length=254, Percent_Identity=27.1653543307087, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI11545785, Length=228, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081985, Length=308, Percent_Identity=36.3636363636364, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI2367212, Length=299, Percent_Identity=30.4347826086957, Blast_Score=129, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI17536757, Length=279, Percent_Identity=33.3333333333333, Blast_Score=138, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI25143471, Length=181, Percent_Identity=32.5966850828729, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324268, Length=286, Percent_Identity=30.4195804195804, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6319447, Length=324, Percent_Identity=28.3950617283951, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI22024126, Length=305, Percent_Identity=31.1475409836066, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI21355201, Length=333, Percent_Identity=27.027027027027, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668781, Length=251, Percent_Identity=31.0756972111554, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356513, Length=251, Percent_Identity=31.0756972111554, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI19920494, Length=163, Percent_Identity=31.9018404907975, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356579, Length=188, Percent_Identity=29.2553191489362, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: =2.1.1.178 [H]

Molecular weight: Translated: 53665; Mature: 53665

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00268 CECROPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVPVKEEFLKRMKELLKEEYEAFLKEYEKKPQKGLRVNTLKIDVENFKKIAPFEIEPIP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCEECCCCC
WCPTGFYYEKEEKAGNHLYHVLGLYYIQEPTAMAVVEVLDPKPGEKILDVSAAPGGKTTH
CCCCCCEECCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
IASKIGDEGLIVANEIDRKRIRALEENVARMGIRNIVLLNERPERLIQAFEGYFDKIVVD
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEE
APCSGEGMFRKDPAARRIWSLNNVLSCSITQRNILRSVAPLLKRGGVLVYSTCTFSPEEN
CCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCCC
EGVIKKFLEENPEFEVVESELSHFFDKGHPEWVDGPKELEKCMRLWPHKVRGEGHFIAKL
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEE
KKNGEDVNVNFKRKVEKKKHQKELELFYQFADKYLDLDLEILNLQVDNNFVYHVPLDLPE
ECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECCCCCC
LKGIRIYRHGWLMGELKKNRFEPSHWLAMGLKPSQIKRVLELDKFQREKYLNGETFELDE
CCCEEEEECCCEEHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECC
EDGWILFTAENFPAGWGRVAKGVVKNYFPKWLRDIEVWEE
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVPVKEEFLKRMKELLKEEYEAFLKEYEKKPQKGLRVNTLKIDVENFKKIAPFEIEPIP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHHCCCCCEECCCCC
WCPTGFYYEKEEKAGNHLYHVLGLYYIQEPTAMAVVEVLDPKPGEKILDVSAAPGGKTTH
CCCCCCEECCHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCHHH
IASKIGDEGLIVANEIDRKRIRALEENVARMGIRNIVLLNERPERLIQAFEGYFDKIVVD
HHHHCCCCCEEEECHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHEEEEE
APCSGEGMFRKDPAARRIWSLNNVLSCSITQRNILRSVAPLLKRGGVLVYSTCTFSPEEN
CCCCCCCCCCCCHHHHHHHHHCCEEEEECHHHHHHHHHHHHHHHCCEEEEEEEECCCCCC
EGVIKKFLEENPEFEVVESELSHFFDKGHPEWVDGPKELEKCMRLWPHKVRGEGHFIAKL
CHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHHCCCCEEEEEE
KKNGEDVNVNFKRKVEKKKHQKELELFYQFADKYLDLDLEILNLQVDNNFVYHVPLDLPE
ECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECCCCCC
LKGIRIYRHGWLMGELKKNRFEPSHWLAMGLKPSQIKRVLELDKFQREKYLNGETFELDE
CCCEEEEECCCEEHHHHHCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEECC
EDGWILFTAENFPAGWGRVAKGVVKNYFPKWLRDIEVWEE
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA