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The map label for this gene is 20808519

Identifier: 20808519

GI number: 20808519

Start: 2044615

End: 2045547

Strand: Direct

Name: 20808519

Synonym: TTE2129

Alternate gene names: NA

Gene position: 2044615-2045547 (Clockwise)

Preceding gene: 20808517

Following gene: 20808520

Centisome position: 76.02

GC content: 36.76

Gene sequence:

>933_bases
ATGTTTGTAGATTTTCACTGCGATACCCTGTACAGGCTGGTAGATAAAGGAACTGATTTCTTTGAAAGGACAGAAGAGAG
GCATGTAGATTTCCCCAGAATGAAGGAGGGAAAAGTGCATCTTCAAGTTTTTGCAGTGTTTGTAGACCCTAAATTTATGA
GAAAGAATGCAGCTACAATGGCTTTAAAACTAATTGATAAAATGCATGAAATAATAGATAAAAGCAGCGAAATTGAATTG
GTACTAAGAGGAGAGGATATTGACAGAATAAAAAGCGAAGGAAAAATTGGAGCTTTGCTCTCAATTGAAGGGGGAGAAGC
CTTAGAAGGAGAAATCGCTTTACTAAGAATATTTTACAAATTGGGAGTAAGAGCTATCACTTTGACCTGGAGTTTAAGAA
ATGACTTAGGGGATGGAGTCGAGGGAGTTCCTGATGCTGGGCTCACATCTTTTGGAAAGCAAGTAGTAAAAGAAATGAAC
CGGCTTGGTATGATAGTAGACGTATCCCATCTCAATGAAAAAGGCTTTTGGGATGTTATAGAAATAAGCGAAAAACCAGT
AATAGCTTCCCATTCAAACGCTAAAGCTTTGTGCTCCCACAGGAGAAATCTGACAGATGAGCAGATAAAAGCAATCGCTC
AAAAGGGAGGAGTAATTGGTATAAATTTCGCTCCTCAATTTTTAAAAGATGACAAAAGAGCAACGATAGAAGATGTATTA
AATCACATAGATTACATGGTGGACTTAGTTGGAGAAGACTACGTAGGATTTGGATCTGACTTTGATGGCATAAGTTCCAC
ACCAGAGGGGTTAGAAGATATATCAAAATTCCCGAAAATTGTAGAAGGGCTTATAAAAAGAGGATATACACAGGAACAAA
TTGATAAAATCACTCACAAAAATTTTGAAAACCTCATAAAAAAGATTTTATAA

Upstream 100 bases:

>100_bases
TATTACAGGATAATTAATTTTTAATTAATGAACTCAAATTCTGAAAATCTTTCTCAGTGTGATACAATCATATTGAGAAG
AATTTGAGGAGGGGATAAAA

Downstream 100 bases:

>100_bases
AACAAAAAGTGCCCCGATCACCGGGGCTTTATATGTTAAAGGGGGAGTCATTGGTTTAACCAAGTATACATTATACATAG
GTTTTTTAAAAAAAGCAAGA

Product: Zn-dependent dipeptidase

Products: NA

Alternate protein names: ORF X [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFVDFHCDTLYRLVDKGTDFFERTEERHVDFPRMKEGKVHLQVFAVFVDPKFMRKNAATMALKLIDKMHEIIDKSSEIEL
VLRGEDIDRIKSEGKIGALLSIEGGEALEGEIALLRIFYKLGVRAITLTWSLRNDLGDGVEGVPDAGLTSFGKQVVKEMN
RLGMIVDVSHLNEKGFWDVIEISEKPVIASHSNAKALCSHRRNLTDEQIKAIAQKGGVIGINFAPQFLKDDKRATIEDVL
NHIDYMVDLVGEDYVGFGSDFDGISSTPEGLEDISKFPKIVEGLIKRGYTQEQIDKITHKNFENLIKKIL

Sequences:

>Translated_310_residues
MFVDFHCDTLYRLVDKGTDFFERTEERHVDFPRMKEGKVHLQVFAVFVDPKFMRKNAATMALKLIDKMHEIIDKSSEIEL
VLRGEDIDRIKSEGKIGALLSIEGGEALEGEIALLRIFYKLGVRAITLTWSLRNDLGDGVEGVPDAGLTSFGKQVVKEMN
RLGMIVDVSHLNEKGFWDVIEISEKPVIASHSNAKALCSHRRNLTDEQIKAIAQKGGVIGINFAPQFLKDDKRATIEDVL
NHIDYMVDLVGEDYVGFGSDFDGISSTPEGLEDISKFPKIVEGLIKRGYTQEQIDKITHKNFENLIKKIL
>Mature_310_residues
MFVDFHCDTLYRLVDKGTDFFERTEERHVDFPRMKEGKVHLQVFAVFVDPKFMRKNAATMALKLIDKMHEIIDKSSEIEL
VLRGEDIDRIKSEGKIGALLSIEGGEALEGEIALLRIFYKLGVRAITLTWSLRNDLGDGVEGVPDAGLTSFGKQVVKEMN
RLGMIVDVSHLNEKGFWDVIEISEKPVIASHSNAKALCSHRRNLTDEQIKAIAQKGGVIGINFAPQFLKDDKRATIEDVL
NHIDYMVDLVGEDYVGFGSDFDGISSTPEGLEDISKFPKIVEGLIKRGYTQEQIDKITHKNFENLIKKIL

Specific function: Unknown

COG id: COG2355

COG function: function code E; Zn-dependent dipeptidase, microsomal dipeptidase homolog

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M19 family [H]

Homologues:

Organism=Homo sapiens, GI189458885, Length=308, Percent_Identity=31.8181818181818, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI4758190, Length=308, Percent_Identity=31.8181818181818, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI11641269, Length=283, Percent_Identity=31.8021201413428, Blast_Score=187, Evalue=9e-48,
Organism=Homo sapiens, GI193211608, Length=283, Percent_Identity=31.4487632508834, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI193211610, Length=283, Percent_Identity=31.8021201413428, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI221475880, Length=296, Percent_Identity=34.1216216216216, Blast_Score=211, Evalue=4e-55,
Organism=Drosophila melanogaster, GI281362638, Length=297, Percent_Identity=34.3434343434343, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI281362636, Length=297, Percent_Identity=34.3434343434343, Blast_Score=199, Evalue=2e-51,
Organism=Drosophila melanogaster, GI161083233, Length=293, Percent_Identity=31.740614334471, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356391, Length=230, Percent_Identity=25.6521739130435, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008257 [H]

Pfam domain/function: PF01244 Peptidase_M19 [H]

EC number: NA

Molecular weight: Translated: 34940; Mature: 34940

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00869 RENAL_DIPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDFHCDTLYRLVDKGTDFFERTEERHVDFPRMKEGKVHLQVFAVFVDPKFMRKNAATM
CEEECHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHH
ALKLIDKMHEIIDKSSEIELVLRGEDIDRIKSEGKIGALLSIEGGEALEGEIALLRIFYK
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHH
LGVRAITLTWSLRNDLGDGVEGVPDAGLTSFGKQVVKEMNRLGMIVDVSHLNEKGFWDVI
HCCEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHCCCCCCEEEE
EISEKPVIASHSNAKALCSHRRNLTDEQIKAIAQKGGVIGINFAPQFLKDDKRATIEDVL
EECCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHH
NHIDYMVDLVGEDYVGFGSDFDGISSTPEGLEDISKFPKIVEGLIKRGYTQEQIDKITHK
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NFENLIKKIL
HHHHHHHHHC
>Mature Secondary Structure
MFVDFHCDTLYRLVDKGTDFFERTEERHVDFPRMKEGKVHLQVFAVFVDPKFMRKNAATM
CEEECHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECHHHHHHHHHHH
ALKLIDKMHEIIDKSSEIELVLRGEDIDRIKSEGKIGALLSIEGGEALEGEIALLRIFYK
HHHHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHH
LGVRAITLTWSLRNDLGDGVEGVPDAGLTSFGKQVVKEMNRLGMIVDVSHLNEKGFWDVI
HCCEEEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHCCCCCCEEEE
EISEKPVIASHSNAKALCSHRRNLTDEQIKAIAQKGGVIGINFAPQFLKDDKRATIEDVL
EECCCCEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHCCCCCHHHHHHH
NHIDYMVDLVGEDYVGFGSDFDGISSTPEGLEDISKFPKIVEGLIKRGYTQEQIDKITHK
HHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
NFENLIKKIL
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1313537 [H]