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The map label for this gene is XylB [H]

Identifier: 20808346

GI number: 20808346

Start: 1887967

End: 1889451

Strand: Reverse

Name: XylB [H]

Synonym: TTE1942

Alternate gene names: 20808346

Gene position: 1889451-1887967 (Counterclockwise)

Preceding gene: 20808347

Following gene: 20808345

Centisome position: 70.25

GC content: 37.31

Gene sequence:

>1485_bases
ATGGAAAAAGATTTGATTCTTTCTGTTGACATAGGGACGACAAACTTAAAAGCAGGTGTGGTGGACGAAAAAGGAAATAT
TTTAAGCTTGTACAGGAAGGAAACGCCTATTGAAAGAGACAACGAAGGAAAAGCAGAGCACGACCCAGATACCCTTTTTA
ACGCTTTTGTAGAAGCAGCAGGGGAGGCGGCAAAAGGCTTTGAAGATAGGATTTCCTTAATCGTTCCTTCTTCTTATATG
TTTGGCTTAATTCCCATAGATGACAAATTAAATCCTTTAATGGGCATTATGACACTTCTGGATTTGAGGGCGAGAGAAAC
CTATGAGGAACTTTTAGAAAGAATTGATGTAAAGGAGGTTTACAGAAGGACAGGCTTTACTCCAACTTTTCATGCCCCTT
TGTTTAAAATTTACTGGTTAAAAAAGAAAAGAAGTGATATATTTAATAAAACAAGGTTTTTCTTGAGCTCTAAAGATTTT
ATACTTTTAAAACTTTTAGGAGAACCTTTTACAGAGCCCAGCCTTTCTTCTGCAACTGCTTATATGAATGTAAATACACT
TGAATGGGATGACTATGTGCTTGATATTTTAGGGGTTTCTAAAGAAAAACTTCCTCCCATCATGCCTTCAGATAAAATTT
TGGCCGATTTGCCCGAACAATCTAAAAAGCTTTTGGGACTAACAAAAGATGTGAAAGTACTTACAGGAGTTTACGATGGA
GGAGCGGTGGGAATAGGAATTGGGGCTTTTGAGGAAGAAGTTGGTGCGATAAACATAGGGACTACTGGAATGTTCAGAGT
AGCCTATCCTGAACCTGTTTTTGACAAAGAAGAGGCTATGAGGCTTCAAACTTATTATTTATCTTCGGGTAAATGGTTCA
TTGGGGCTGCTATAAACAATGCAGGAGTTGTACTAAAATGGCTTAGAGACAATATTTTTAACATGCCCTATGAAGAATTA
ACTCATGAGGCTTCAAAAGAAGATTCTTCAAATCTCTTTTTCCTGCCCTACTTGACAGGTGAAAGGGACAAAGAAATAGG
AAATATTGCATCAGGAGTGTTTTTTGGATTAAAGAATATTCACACAAAGGGTCATATGATAAGAGCGGCTATGGAAGGAG
TAGCCTTTTCCCTGCGCATGATTTATGAGGCGTTGAAGGACAATAATATAAAGATAAGAGAAATTAGGGCAGGAGGAGGA
GCGACAAATTCACCATTCTGGATGGAAATTTTTGCATCGACACTGGGGCTGCCTATTAAAGTCTCTAAAGTAGAAGAACC
TGCTCTTGTTGGCTCCGCTATTCTAGGATACTATGTTCTTGGAAGATACAAAGATTTATCTGAAGCTACGAAGGAAATGG
TTAGTGTAGAAAATGTTTATATGCCAGACGAAAAAGAGATCAATTATTATGAAAAGAAATTTCAATTTTTCAAAAAATTA
TCTCGAGAGCTCAAAAGCCTATTCGAAGCTCACAGCAAATTATAA

Upstream 100 bases:

>100_bases
TAAAAGGCATGGGAGATAAAGTTGTTTCAGATGCAGAAAAAGTCCTACGAGGCGAAATACCCGATGGGGTTGTAAATAAA
GAGGTGCTGGAGGGGGAGAA

Downstream 100 bases:

>100_bases
AACAGGAGGTATTAAAAATGAATGAAATAGGGCTGATTGGCTTAGCAGTTATGGGTCAAAATTTAGCTTTAAACATTGCC
AGGAAAGGTTATTCCGTATC

Product: sugar (pentulose and hexulose) kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MEKDLILSVDIGTTNLKAGVVDEKGNILSLYRKETPIERDNEGKAEHDPDTLFNAFVEAAGEAAKGFEDRISLIVPSSYM
FGLIPIDDKLNPLMGIMTLLDLRARETYEELLERIDVKEVYRRTGFTPTFHAPLFKIYWLKKKRSDIFNKTRFFLSSKDF
ILLKLLGEPFTEPSLSSATAYMNVNTLEWDDYVLDILGVSKEKLPPIMPSDKILADLPEQSKKLLGLTKDVKVLTGVYDG
GAVGIGIGAFEEEVGAINIGTTGMFRVAYPEPVFDKEEAMRLQTYYLSSGKWFIGAAINNAGVVLKWLRDNIFNMPYEEL
THEASKEDSSNLFFLPYLTGERDKEIGNIASGVFFGLKNIHTKGHMIRAAMEGVAFSLRMIYEALKDNNIKIREIRAGGG
ATNSPFWMEIFASTLGLPIKVSKVEEPALVGSAILGYYVLGRYKDLSEATKEMVSVENVYMPDEKEINYYEKKFQFFKKL
SRELKSLFEAHSKL

Sequences:

>Translated_494_residues
MEKDLILSVDIGTTNLKAGVVDEKGNILSLYRKETPIERDNEGKAEHDPDTLFNAFVEAAGEAAKGFEDRISLIVPSSYM
FGLIPIDDKLNPLMGIMTLLDLRARETYEELLERIDVKEVYRRTGFTPTFHAPLFKIYWLKKKRSDIFNKTRFFLSSKDF
ILLKLLGEPFTEPSLSSATAYMNVNTLEWDDYVLDILGVSKEKLPPIMPSDKILADLPEQSKKLLGLTKDVKVLTGVYDG
GAVGIGIGAFEEEVGAINIGTTGMFRVAYPEPVFDKEEAMRLQTYYLSSGKWFIGAAINNAGVVLKWLRDNIFNMPYEEL
THEASKEDSSNLFFLPYLTGERDKEIGNIASGVFFGLKNIHTKGHMIRAAMEGVAFSLRMIYEALKDNNIKIREIRAGGG
ATNSPFWMEIFASTLGLPIKVSKVEEPALVGSAILGYYVLGRYKDLSEATKEMVSVENVYMPDEKEINYYEKKFQFFKKL
SRELKSLFEAHSKL
>Mature_494_residues
MEKDLILSVDIGTTNLKAGVVDEKGNILSLYRKETPIERDNEGKAEHDPDTLFNAFVEAAGEAAKGFEDRISLIVPSSYM
FGLIPIDDKLNPLMGIMTLLDLRARETYEELLERIDVKEVYRRTGFTPTFHAPLFKIYWLKKKRSDIFNKTRFFLSSKDF
ILLKLLGEPFTEPSLSSATAYMNVNTLEWDDYVLDILGVSKEKLPPIMPSDKILADLPEQSKKLLGLTKDVKVLTGVYDG
GAVGIGIGAFEEEVGAINIGTTGMFRVAYPEPVFDKEEAMRLQTYYLSSGKWFIGAAINNAGVVLKWLRDNIFNMPYEEL
THEASKEDSSNLFFLPYLTGERDKEIGNIASGVFFGLKNIHTKGHMIRAAMEGVAFSLRMIYEALKDNNIKIREIRAGGG
ATNSPFWMEIFASTLGLPIKVSKVEEPALVGSAILGYYVLGRYKDLSEATKEMVSVENVYMPDEKEINYYEKKFQFFKKL
SRELKSLFEAHSKL

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=444, Percent_Identity=25, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI4504007, Length=444, Percent_Identity=25, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI189409120, Length=444, Percent_Identity=25, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI41393575, Length=443, Percent_Identity=25.2821670428894, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI164663828, Length=544, Percent_Identity=22.0588235294118, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI88196792, Length=515, Percent_Identity=22.7184466019417, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI164663830, Length=117, Percent_Identity=31.6239316239316, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=25.1012145748988, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789987, Length=493, Percent_Identity=24.3407707910751, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787789, Length=493, Percent_Identity=23.1237322515213, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1790361, Length=512, Percent_Identity=23.6328125, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789168, Length=468, Percent_Identity=21.7948717948718, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789138, Length=522, Percent_Identity=20.8812260536398, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71986140, Length=516, Percent_Identity=23.2558139534884, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71986147, Length=293, Percent_Identity=25.938566552901, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17535599, Length=455, Percent_Identity=22.6373626373626, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24655555, Length=461, Percent_Identity=23.2104121475054, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655560, Length=461, Percent_Identity=23.2104121475054, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655570, Length=461, Percent_Identity=23.2104121475054, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655574, Length=461, Percent_Identity=23.2104121475054, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655565, Length=461, Percent_Identity=23.2104121475054, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17864214, Length=528, Percent_Identity=24.6212121212121, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24654573, Length=432, Percent_Identity=25.2314814814815, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24656367, Length=532, Percent_Identity=22.5563909774436, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21357867, Length=548, Percent_Identity=22.4452554744526, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24656372, Length=346, Percent_Identity=23.9884393063584, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 55712; Mature: 55712

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKDLILSVDIGTTNLKAGVVDEKGNILSLYRKETPIERDNEGKAEHDPDTLFNAFVEAA
CCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GEAAKGFEDRISLIVPSSYMFGLIPIDDKLNPLMGIMTLLDLRARETYEELLERIDVKEV
CHHHCCHHHCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YRRTGFTPTFHAPLFKIYWLKKKRSDIFNKTRFFLSSKDFILLKLLGEPFTEPSLSSATA
HHHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEE
YMNVNTLEWDDYVLDILGVSKEKLPPIMPSDKILADLPEQSKKLLGLTKDVKVLTGVYDG
EEEEEEECHHHHHHHHHCCCHHHCCCCCCCCHHHHCCCHHHHHHHCCCCCHHHEEEECCC
GAVGIGIGAFEEEVGAINIGTTGMFRVAYPEPVFDKEEAMRLQTYYLSSGKWFIGAAINN
CEEEEECCCHHHCCCEEEECCCCEEEEECCCCCCCHHHHHEEEEEEECCCCEEEEEEECC
AGVVLKWLRDNIFNMPYEELTHEASKEDSSNLFFLPYLTGERDKEIGNIASGVFFGLKNI
CCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
HTKGHMIRAAMEGVAFSLRMIYEALKDNNIKIREIRAGGGATNSPFWMEIFASTLGLPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEE
VSKVEEPALVGSAILGYYVLGRYKDLSEATKEMVSVENVYMPDEKEINYYEKKFQFFKKL
ECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
SRELKSLFEAHSKL
HHHHHHHHHHHHCC
>Mature Secondary Structure
MEKDLILSVDIGTTNLKAGVVDEKGNILSLYRKETPIERDNEGKAEHDPDTLFNAFVEAA
CCCCEEEEEECCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GEAAKGFEDRISLIVPSSYMFGLIPIDDKLNPLMGIMTLLDLRARETYEELLERIDVKEV
CHHHCCHHHCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
YRRTGFTPTFHAPLFKIYWLKKKRSDIFNKTRFFLSSKDFILLKLLGEPFTEPSLSSATA
HHHCCCCCCCCCCHHHEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCEE
YMNVNTLEWDDYVLDILGVSKEKLPPIMPSDKILADLPEQSKKLLGLTKDVKVLTGVYDG
EEEEEEECHHHHHHHHHCCCHHHCCCCCCCCHHHHCCCHHHHHHHCCCCCHHHEEEECCC
GAVGIGIGAFEEEVGAINIGTTGMFRVAYPEPVFDKEEAMRLQTYYLSSGKWFIGAAINN
CEEEEECCCHHHCCCEEEECCCCEEEEECCCCCCCHHHHHEEEEEEECCCCEEEEEEECC
AGVVLKWLRDNIFNMPYEELTHEASKEDSSNLFFLPYLTGERDKEIGNIASGVFFGLKNI
CCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHC
HTKGHMIRAAMEGVAFSLRMIYEALKDNNIKIREIRAGGGATNSPFWMEIFASTLGLPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCEE
VSKVEEPALVGSAILGYYVLGRYKDLSEATKEMVSVENVYMPDEKEINYYEKKFQFFKKL
ECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
SRELKSLFEAHSKL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]