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The map label for this gene is Lgt

Identifier: 20808163

GI number: 20808163

Start: 1687726

End: 1688499

Strand: Reverse

Name: Lgt

Synonym: TTE1744

Alternate gene names: 20808163

Gene position: 1688499-1687726 (Counterclockwise)

Preceding gene: 20808165

Following gene: 20808162

Centisome position: 62.78

GC content: 40.31

Gene sequence:

>774_bases
ATGGACATTCCTTCATTGAGCCCATATGCTTTTAAATTCGGACCTATTGCCGTTCACTGGTATGGAATTTTTATGGCTAT
TTCTATTGCGGTAGGAGGATACTACCTTTATAAGCAGGCGACGAAATTGAATTACGATGAGGATTTTTTGTTAAACCTTT
TAATGATAGTTGTGATATTTGGGGTTATTGGAGCAAGACTCATGTTTGTGCTTGCCAACTATCCTGAGTGGTTTGTTAAA
GACCCTGTACAGGTTTTTAAAATTTACGAAGGTGGGCTTTCATGGCATGGTGCAGTACTTGGCGGCTTTTTGGCAGGTCT
TTATTATTGCCGAAAAAAGGGAGTTAGAATAAATCCTCTGGAAGATTTCGCTGTAGTTGGGCTGGCTTTGGGAAATATGC
TGGTGAGAGTGGGCAACATATTTAACCATGAGGTTTTGGGAAGGCCGACAGAGTTTTTCTTCGGCAGATGGCCAGCCCAG
CTCGTTGGTGTAGCTATAGGAGCTTTTCTTCTCATAAGGTATTTTTACGTGCAGAAAAAGCACATGCCTGACGGTTATCA
GTTTTGGTCTTTTATCTTTTATTACCAGCTTTTAAGAGGAGTGTTTGAGGAGACTGTAAAAGACGTACCTCTTGTGTGGC
CTGTATATTTAAATGAAGAATGGGGTATTGGATTGTTTACTATGACGCAGGTGGCTACTCCATTTATATTAATACTGGCT
TACTGGATGATTAAAAGAGTTTTGAATGACCCTAACAGGCAGTATTACGATTGA

Upstream 100 bases:

>100_bases
ATATACTAGAAAACTTTGAAAAAATCAATCCTCTTGACATGCTGTTGAAATGCTGTAAAATGGTATTATACAATGAAAAT
CGAAGTTGGAGGTAGCGATA

Downstream 100 bases:

>100_bases
GTTTTTGTTTTTGATAGGTTTTATGGTAAAATTATATTGACAAAATTTTTACAAGGGAGTTGTAGCTATGGAAAAGCAAA
AGGTTTTTGAAAGGTTGATT

Product: prolipoprotein diacylglyceryl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDIPSLSPYAFKFGPIAVHWYGIFMAISIAVGGYYLYKQATKLNYDEDFLLNLLMIVVIFGVIGARLMFVLANYPEWFVK
DPVQVFKIYEGGLSWHGAVLGGFLAGLYYCRKKGVRINPLEDFAVVGLALGNMLVRVGNIFNHEVLGRPTEFFFGRWPAQ
LVGVAIGAFLLIRYFYVQKKHMPDGYQFWSFIFYYQLLRGVFEETVKDVPLVWPVYLNEEWGIGLFTMTQVATPFILILA
YWMIKRVLNDPNRQYYD

Sequences:

>Translated_257_residues
MDIPSLSPYAFKFGPIAVHWYGIFMAISIAVGGYYLYKQATKLNYDEDFLLNLLMIVVIFGVIGARLMFVLANYPEWFVK
DPVQVFKIYEGGLSWHGAVLGGFLAGLYYCRKKGVRINPLEDFAVVGLALGNMLVRVGNIFNHEVLGRPTEFFFGRWPAQ
LVGVAIGAFLLIRYFYVQKKHMPDGYQFWSFIFYYQLLRGVFEETVKDVPLVWPVYLNEEWGIGLFTMTQVATPFILILA
YWMIKRVLNDPNRQYYD
>Mature_257_residues
MDIPSLSPYAFKFGPIAVHWYGIFMAISIAVGGYYLYKQATKLNYDEDFLLNLLMIVVIFGVIGARLMFVLANYPEWFVK
DPVQVFKIYEGGLSWHGAVLGGFLAGLYYCRKKGVRINPLEDFAVVGLALGNMLVRVGNIFNHEVLGRPTEFFFGRWPAQ
LVGVAIGAFLLIRYFYVQKKHMPDGYQFWSFIFYYQLLRGVFEETVKDVPLVWPVYLNEEWGIGLFTMTQVATPFILILA
YWMIKRVLNDPNRQYYD

Specific function: Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins

COG id: COG0682

COG function: function code M; Prolipoprotein diacylglyceryltransferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lgt family

Homologues:

Organism=Escherichia coli, GI1789192, Length=151, Percent_Identity=27.1523178807947, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LGT_THETN (Q8R980)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623334.1
- GeneID:   996756
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1744
- NMPDR:   fig|273068.3.peg.1718
- HOGENOM:   HBG563090
- OMA:   NFMNAEL
- ProtClustDB:   PRK00052
- BioCyc:   TTEN273068:TTE1744-MONOMER
- HAMAP:   MF_01147
- InterPro:   IPR001640

Pfam domain/function: PF01790 LGT

EC number: 2.4.99.- [C]

Molecular weight: Translated: 29719; Mature: 29719

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS01311 LGT

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xeb91cc4)-; HASH(0xef22b84)-; HASH(0xf044e74)-; HASH(0xd0fcaa0)-; HASH(0xeac3e94)-; HASH(0xeb13268)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHCCCCCCCCH
>Mature Secondary Structure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HHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11997336