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The map label for this gene is pheT

Identifier: 20808114

GI number: 20808114

Start: 1638569

End: 1640953

Strand: Reverse

Name: pheT

Synonym: TTE1688

Alternate gene names: 20808114

Gene position: 1640953-1638569 (Counterclockwise)

Preceding gene: 20808115

Following gene: 20808113

Centisome position: 61.01

GC content: 41.84

Gene sequence:

>2385_bases
ATGTTAGTGTCTCTTTCTTGGTTGAAAGAATTTGTAGATATAGATGAAGACGCTAAGACAATAGCCGAAGGGTTGACCAT
GTCTGGTTCGAAAGTGGAAGGCATAAAAAGTTACGGGGAAGAAATTTCCAATGTAGTTGTAGGGCAGATTGTATCTTTGG
AAAAACATCCTAATGCAGATAAATTGTGGGTTGGGATTGTGGACATTGGAAGTGAAAAATTGCAGATTGTCACAGGGGCA
GAAAATATAAAGGTAGGGGCCTATATACCGGTAGCATTGCACGGTGCTACTCTTCCGGGTGGAGTGAAGATAAAAAGAAG
CAAATTAAGAGGAGTAGAGTCTGAGGGCATGATGTGTTCTGCGGAAGAGCTGGGGCTTGATGAGAGCCTGCTGCCTGAGT
ATCAGAGAAACGGGATATTCATCCTGCCTCCACTTCCTCTTGGGATGGACATAAATGAGGCATTGCAGCTTAAAGATGAT
GTTTTAGAATTTGAGATAACGCCAAATCGCCCCGACTGTCTATCTGTAGTTGGAATTGCGAGAGAGACTGCGGCAACTTT
CAGAAAATCTTTCAGAATGCCAGAAATCAGAGTTACAGAAGTGGAGGAGCCCAATCCTGCCAGAGTGACTATAGAGGCGC
CGGACCTTTGCTACAGGTACGTTGCGAGGGTCGTGAAAAATGTCAAAATAGGTCCTTCCCCCATCTGGATGCAGGTAAGG
CTGTTGAAGGCAGGTATAAGGCCTATAAACAACGTAGTAGATGTGACTAACTATGTGATGCTGGAGCTGGGACAGCCTCT
GCACGCTTTTGATTTGGACAAAGTAAAGAATAAACACATAATTGTGAGAAGGGCAAGAGACGGAGAAAAATTGGTTACTC
TAGACGGGAAAGAGAGGATTTTAGATAGTTCAATGCTTGTGATAGCGGACGAAGAAAAGGCAATAGGCCTTGCAGGAGTA
ATGGGAGGAGAGAACACAGAAATAACGGATTCCACAGTGAATATACTCATAGAGAGTGCCAATTTCAAAGGCAGCAATAT
AAGGCATACCTCCAAAAAGCTGGGTCTTAGAAGCGAGGCTTCAGCGAGGTTTGAAAAAGGGCTAGACCCAGAAATTACAG
TTCTTGCCTGTGAGAGAGCAGCCCAGCTCATGGAAAAGTACTGCGGTGGAGAGGTATTAAAAGGAATTGTGGATGAATAT
CCGAAGCCAATGGAAAGAACAGTATTGACTGTAAGGCCTGATAGGATAAATAAATTTTTGGGCACAAATTTAGCTACCTC
TGAAATGATTGAGATCTTAAGGTCTTTAGAATTTGAAGTAGTTGAAAAAGGAGAAGAGCTTGAAATAAAAGTTCCTCACT
TCAGAAAAGATGTGACTATGGAGGCAGATATTGCAGAAGAAATAGCTAGGCTTTATGGTTACAACAATATTGAAGATAGT
CTTATGAAAAATGCTCAGACCACTTTAGGTTCTCTTACAAAAGAGCAGCAGCTGGAAGAAAAGGCGAGAGAAGTACTGCT
GGCTTGTGGACTAAATGAGATTGTCACAATGTCATTTATGGGAGAGAGGGATTTAGACAGAATAAATGTTCCTAAAGACA
GTGTTTTGAGGAAAGCTGTCAAGATAATAAATCCCCTTGGCGAAGAGCAAAGCCTTATGAGGACTACACTTTTGCCTTTT
ATGCTAAATGTGGCTTATACCAATTACAGCAGAAAAGTGGGGGAATTTAGGGCTTTTGAAATCTCAAGGGTATTTTTACC
AAAAGAACTGCCTTTGAAGGAACTGCCTGAAGAGGTAAAGACTATTTCTCTGGGAATGTACGGCAAGGAAGTGGACTTTT
ACACCATAAAAGGAGTAATTGAAGAACTGCTTGAAGTGATGGGGATTGTTGATGTAGAATATGTGAGGGCAGAGGAACCT
TCTTATCATCCTGGAAGGTCAGCAAAAATACTCTTTAAAGAAGAAGTATTGGGTGTCTTTGGAGAAGTTCATCCGGATGT
TTTGGAAAATTATGACTTGCCCGTGAGAGTGTATGCGGGGGAGTTGAATTTGGATAAAATCATAAAATTTGCTAATGTAG
ATAAAAAGTACACCCCGCTTCCCAAATACCCTGCAGTTGAAAGGGATATCGCAGTGGTCGTAGATAAGGATTTGTTTGTG
GCTGAAGTTGAAAAAGTAATAAAAGAGACCGGCAGAGGGTTTGTAGAAAAAACTGCCCTGTTTGATGTTTACAAAGGACC
CAACATCCCTGAAGGAAAGAAGAGCGTCGCCTTTTCCATCTGGTACAGGTCTTATGAGAAAACCTTGACCGATGAAGAAG
TCAATGAAGTCCATGCTAGGATAGTTAAGGCTTTAGAGGAAAAATTGGGGGCTAAATTGAGGTAA

Upstream 100 bases:

>100_bases
GAATAGACAGGATAGCGATGTTAAAATATGGGATAGAAGATTTGAGATTGTTATTTGAAAACGACATGAGATTTATAGAA
CAATTTTAAGGGGTGAGCTT

Downstream 100 bases:

>100_bases
AAAAGAAGGAAAATTGCTTTTTATGTAGAAATAAATAGAATAACAAAGGATTAAGGGGATGTTTCTGTGGAGTTAAACAG
GGTTAGTGTAACGATTAATG

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MLVSLSWLKEFVDIDEDAKTIAEGLTMSGSKVEGIKSYGEEISNVVVGQIVSLEKHPNADKLWVGIVDIGSEKLQIVTGA
ENIKVGAYIPVALHGATLPGGVKIKRSKLRGVESEGMMCSAEELGLDESLLPEYQRNGIFILPPLPLGMDINEALQLKDD
VLEFEITPNRPDCLSVVGIARETAATFRKSFRMPEIRVTEVEEPNPARVTIEAPDLCYRYVARVVKNVKIGPSPIWMQVR
LLKAGIRPINNVVDVTNYVMLELGQPLHAFDLDKVKNKHIIVRRARDGEKLVTLDGKERILDSSMLVIADEEKAIGLAGV
MGGENTEITDSTVNILIESANFKGSNIRHTSKKLGLRSEASARFEKGLDPEITVLACERAAQLMEKYCGGEVLKGIVDEY
PKPMERTVLTVRPDRINKFLGTNLATSEMIEILRSLEFEVVEKGEELEIKVPHFRKDVTMEADIAEEIARLYGYNNIEDS
LMKNAQTTLGSLTKEQQLEEKAREVLLACGLNEIVTMSFMGERDLDRINVPKDSVLRKAVKIINPLGEEQSLMRTTLLPF
MLNVAYTNYSRKVGEFRAFEISRVFLPKELPLKELPEEVKTISLGMYGKEVDFYTIKGVIEELLEVMGIVDVEYVRAEEP
SYHPGRSAKILFKEEVLGVFGEVHPDVLENYDLPVRVYAGELNLDKIIKFANVDKKYTPLPKYPAVERDIAVVVDKDLFV
AEVEKVIKETGRGFVEKTALFDVYKGPNIPEGKKSVAFSIWYRSYEKTLTDEEVNEVHARIVKALEEKLGAKLR

Sequences:

>Translated_794_residues
MLVSLSWLKEFVDIDEDAKTIAEGLTMSGSKVEGIKSYGEEISNVVVGQIVSLEKHPNADKLWVGIVDIGSEKLQIVTGA
ENIKVGAYIPVALHGATLPGGVKIKRSKLRGVESEGMMCSAEELGLDESLLPEYQRNGIFILPPLPLGMDINEALQLKDD
VLEFEITPNRPDCLSVVGIARETAATFRKSFRMPEIRVTEVEEPNPARVTIEAPDLCYRYVARVVKNVKIGPSPIWMQVR
LLKAGIRPINNVVDVTNYVMLELGQPLHAFDLDKVKNKHIIVRRARDGEKLVTLDGKERILDSSMLVIADEEKAIGLAGV
MGGENTEITDSTVNILIESANFKGSNIRHTSKKLGLRSEASARFEKGLDPEITVLACERAAQLMEKYCGGEVLKGIVDEY
PKPMERTVLTVRPDRINKFLGTNLATSEMIEILRSLEFEVVEKGEELEIKVPHFRKDVTMEADIAEEIARLYGYNNIEDS
LMKNAQTTLGSLTKEQQLEEKAREVLLACGLNEIVTMSFMGERDLDRINVPKDSVLRKAVKIINPLGEEQSLMRTTLLPF
MLNVAYTNYSRKVGEFRAFEISRVFLPKELPLKELPEEVKTISLGMYGKEVDFYTIKGVIEELLEVMGIVDVEYVRAEEP
SYHPGRSAKILFKEEVLGVFGEVHPDVLENYDLPVRVYAGELNLDKIIKFANVDKKYTPLPKYPAVERDIAVVVDKDLFV
AEVEKVIKETGRGFVEKTALFDVYKGPNIPEGKKSVAFSIWYRSYEKTLTDEEVNEVHARIVKALEEKLGAKLR
>Mature_794_residues
MLVSLSWLKEFVDIDEDAKTIAEGLTMSGSKVEGIKSYGEEISNVVVGQIVSLEKHPNADKLWVGIVDIGSEKLQIVTGA
ENIKVGAYIPVALHGATLPGGVKIKRSKLRGVESEGMMCSAEELGLDESLLPEYQRNGIFILPPLPLGMDINEALQLKDD
VLEFEITPNRPDCLSVVGIARETAATFRKSFRMPEIRVTEVEEPNPARVTIEAPDLCYRYVARVVKNVKIGPSPIWMQVR
LLKAGIRPINNVVDVTNYVMLELGQPLHAFDLDKVKNKHIIVRRARDGEKLVTLDGKERILDSSMLVIADEEKAIGLAGV
MGGENTEITDSTVNILIESANFKGSNIRHTSKKLGLRSEASARFEKGLDPEITVLACERAAQLMEKYCGGEVLKGIVDEY
PKPMERTVLTVRPDRINKFLGTNLATSEMIEILRSLEFEVVEKGEELEIKVPHFRKDVTMEADIAEEIARLYGYNNIEDS
LMKNAQTTLGSLTKEQQLEEKAREVLLACGLNEIVTMSFMGERDLDRINVPKDSVLRKAVKIINPLGEEQSLMRTTLLPF
MLNVAYTNYSRKVGEFRAFEISRVFLPKELPLKELPEEVKTISLGMYGKEVDFYTIKGVIEELLEVMGIVDVEYVRAEEP
SYHPGRSAKILFKEEVLGVFGEVHPDVLENYDLPVRVYAGELNLDKIIKFANVDKKYTPLPKYPAVERDIAVVVDKDLFV
AEVEKVIKETGRGFVEKTALFDVYKGPNIPEGKKSVAFSIWYRSYEKTLTDEEVNEVHARIVKALEEKLGAKLR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain

Homologues:

Organism=Homo sapiens, GI124028525, Length=380, Percent_Identity=28.1578947368421, Blast_Score=113, Evalue=7e-25,
Organism=Escherichia coli, GI1788006, Length=810, Percent_Identity=37.5308641975309, Blast_Score=488, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI17533403, Length=577, Percent_Identity=22.8769497400347, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355211, Length=399, Percent_Identity=27.5689223057644, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFB_THETN (Q8R9C7)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_623285.1
- ProteinModelPortal:   Q8R9C7
- GeneID:   996395
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1688
- NMPDR:   fig|273068.3.peg.1669
- HOGENOM:   HBG399638
- OMA:   ADKLRVC
- ProtClustDB:   PRK00629
- BioCyc:   TTEN273068:TTE1688-MONOMER
- BRENDA:   6.1.1.20
- GO:   GO:0005737
- HAMAP:   MF_00283
- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547
- Gene3D:   G3DSA:3.50.40.10
- Gene3D:   G3DSA:3.30.56.20
- Gene3D:   G3DSA:3.30.70.380
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00873
- SMART:   SM00874
- SMART:   SM00896
- TIGRFAMs:   TIGR00472

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind; SSF56037 B3_4; SSF54991 Fdx_AntiC_bd; SSF50249 Nucleic_acid_OB; SSF46955 Putativ_DNA_bind

EC number: =6.1.1.20

Molecular weight: Translated: 88956; Mature: 88956

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS51483 B5; PS51447 FDX_ACB; PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSLSWLKEFVDIDEDAKTIAEGLTMSGSKVEGIKSYGEEISNVVVGQIVSLEKHPNAD
CEEEHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLWVGIVDIGSEKLQIVTGAENIKVGAYIPVALHGATLPGGVKIKRSKLRGVESEGMMCS
EEEEEEEECCCCEEEEEECCCCEEEEEEEEEEEECCCCCCCCEEEHHHHCCCCCCCCEEC
AEELGLDESLLPEYQRNGIFILPPLPLGMDINEALQLKDDVLEFEITPNRPDCLSVVGIA
HHHCCCCHHHCCHHHCCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RETAATFRKSFRMPEIRVTEVEEPNPARVTIEAPDLCYRYVARVVKNVKIGPSPIWMQVR
HHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLKAGIRPINNVVDVTNYVMLELGQPLHAFDLDKVKNKHIIVRRARDGEKLVTLDGKERI
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCEEEEECCHHHH
LDSSMLVIADEEKAIGLAGVMGGENTEITDSTVNILIESANFKGSNIRHTSKKLGLRSEA
HCCCEEEEECCCCCEEEEEEECCCCCEECCCEEEEEEECCCCCCCCCCCHHHHCCCCCHH
SARFEKGLDPEITVLACERAAQLMEKYCGGEVLKGIVDEYPKPMERTVLTVRPDRINKFL
HHHHHCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEEEECHHHHHHHH
GTNLATSEMIEILRSLEFEVVEKGEELEIKVPHFRKDVTMEADIAEEIARLYGYNNIEDS
CCCCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
LMKNAQTTLGSLTKEQQLEEKAREVLLACGLNEIVTMSFMGERDLDRINVPKDSVLRKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHCCCCCCCCCCCCHHHHHHHHH
KIINPLGEEQSLMRTTLLPFMLNVAYTNYSRKVGEFRAFEISRVFLPKELPLKELPEEVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCEEEEEEEEEECCCCCCHHHCHHHHH
TISLGMYGKEVDFYTIKGVIEELLEVMGIVDVEYVRAEEPSYHPGRSAKILFKEEVLGVF
EEEECCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHH
GEVHPDVLENYDLPVRVYAGELNLDKIIKFANVDKKYTPLPKYPAVERDIAVVVDKDLFV
HCCCHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHH
AEVEKVIKETGRGFVEKTALFDVYKGPNIPEGKKSVAFSIWYRSYEKTLTDEEVNEVHAR
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHEEEEEHHHHHHHHCCHHHHHHHHHH
IVKALEEKLGAKLR
HHHHHHHHHCCCCC
>Mature Secondary Structure
MLVSLSWLKEFVDIDEDAKTIAEGLTMSGSKVEGIKSYGEEISNVVVGQIVSLEKHPNAD
CEEEHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KLWVGIVDIGSEKLQIVTGAENIKVGAYIPVALHGATLPGGVKIKRSKLRGVESEGMMCS
EEEEEEEECCCCEEEEEECCCCEEEEEEEEEEEECCCCCCCCEEEHHHHCCCCCCCCEEC
AEELGLDESLLPEYQRNGIFILPPLPLGMDINEALQLKDDVLEFEITPNRPDCLSVVGIA
HHHCCCCHHHCCHHHCCCEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHH
RETAATFRKSFRMPEIRVTEVEEPNPARVTIEAPDLCYRYVARVVKNVKIGPSPIWMQVR
HHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHHCCCCCCCCHHHHHH
LLKAGIRPINNVVDVTNYVMLELGQPLHAFDLDKVKNKHIIVRRARDGEKLVTLDGKERI
HHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEEEECCCCCEEEEECCHHHH
LDSSMLVIADEEKAIGLAGVMGGENTEITDSTVNILIESANFKGSNIRHTSKKLGLRSEA
HCCCEEEEECCCCCEEEEEEECCCCCEECCCEEEEEEECCCCCCCCCCCHHHHCCCCCHH
SARFEKGLDPEITVLACERAAQLMEKYCGGEVLKGIVDEYPKPMERTVLTVRPDRINKFL
HHHHHCCCCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHEEEEECHHHHHHHH
GTNLATSEMIEILRSLEFEVVEKGEELEIKVPHFRKDVTMEADIAEEIARLYGYNNIEDS
CCCCCHHHHHHHHHHCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCHHHH
LMKNAQTTLGSLTKEQQLEEKAREVLLACGLNEIVTMSFMGERDLDRINVPKDSVLRKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEHHCCCCCCCCCCCCHHHHHHHHH
KIINPLGEEQSLMRTTLLPFMLNVAYTNYSRKVGEFRAFEISRVFLPKELPLKELPEEVK
HHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCEEEEEEEEEECCCCCCHHHCHHHHH
TISLGMYGKEVDFYTIKGVIEELLEVMGIVDVEYVRAEEPSYHPGRSAKILFKEEVLGVF
EEEECCCCCCCCCEEHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHH
GEVHPDVLENYDLPVRVYAGELNLDKIIKFANVDKKYTPLPKYPAVERDIAVVVDKDLFV
HCCCHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHH
AEVEKVIKETGRGFVEKTALFDVYKGPNIPEGKKSVAFSIWYRSYEKTLTDEEVNEVHAR
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHEEEEEHHHHHHHHCCHHHHHHHHHH
IVKALEEKLGAKLR
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336