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The map label for this gene is HsdS [C]

Identifier: 20807979

GI number: 20807979

Start: 1504205

End: 1505401

Strand: Reverse

Name: HsdS [C]

Synonym: TTE1545

Alternate gene names: 20807979

Gene position: 1505401-1504205 (Counterclockwise)

Preceding gene: 20807980

Following gene: 20807978

Centisome position: 55.97

GC content: 50.96

Gene sequence:

>1197_bases
GTGACAGAGGGACCGTACAAGCTTCCCCCCGGCTGGCGCTGGGTGAGGTTGGGGGAGGTGTGTCTTCCTACCGAAAGGCG
GGATCCTACCAAGAACCCTTCAACCTACTTTGTATATGTGGACATTTCTGCTATAGACAGCACTGTAGGCAAGATAGTGT
CGCCAAAGGAGATATTAGGGCAGCATGCACCTAGCCGGGCACGTAAGGTAATCCGAAGCGGTGACGTAATTTTTGCTACC
ACGCGTCCTTATCTCAAAAATATTGCTTTGGTGCCTCCGGATTTGGACGGACAAATTTGCTCAACAGGCTTTTGCGTGAT
CCGTGCAAATCGAGAATTTGCTGAACCAGAGTTTTTATTTCACTTGTGCCGTTCCGATTTCATAACCAACCAGCTTACTG
CTAGTAAAATGCGCGGAACTAGTTACCCGGCGGTAACTGACAACGATGTTTACAATACCCTCATTCCCCTCCCGCCCCTG
GAGGAGCAGCGGCGCATCGTGGCGAAGGTTGAAGCTCTGATGGAGCGGGTGCGTGAGGTGCGCCGCCTGCGAGCTGAAGC
TCAGAAAGATACAGAGCTTCTTATGCAGACGGCTTTGGCCGAAGTCTTTCCCCACCCCGGCGCCGATCTCCCTCCCGGCT
GGCGCTGGGTAAGGTTGGGTGAGGTATGTGATATTATTATGGGACAATCTCCACCGAGTTCTACTTACAATTTTGAAGGT
AATGGACTTCCTTTCTTTCAGGGAAAAGCCGACTTTGGAGATTTACATCCCACACCTCGTATATGGTGTTCTGCGCCTCA
AAAAGTGGCACGGCCAGGTGATGTTTTAATAAGCGTACGTGCTCCAGTAGGTTCTACCAATGTTGCCAACTTGGCTTGTT
GTATTGGGCGCGGTTTAGCAGCTCTCCGACCCCGTGATTCTCTGGAACGCTTCTGGCTTCTGTACTACCTTCACTACCTC
GAACCTGAACTTTCTAAAATGGGGGCCGGTTCGACTTTCAATGCAATTACCAAGAAAGACCTTCAAAATGTCTTTATCCC
CCTCCCACCCCTTGAAGAGCAGCGACGCATTGTAGCTTACCTTGACCAGATTCAGCAGCAGGTGGCAGCTCTCAAGCGAG
CCCAGGCAGAAACTGAAGCCGAACTTAAGCGCCTGGAGCAGGCAATTTTAGATAAAGCCTTTCGAGGTGATCTATGA

Upstream 100 bases:

>100_bases
TTTTGACCCGCGGTATACATGGCACTTATGTTTATTGTGAAGACGAGGCAACTGCTCGGTTTTTGCGCGAGATAGCGTCT
TCGAAAGGGGGTAGATCCCT

Downstream 100 bases:

>100_bases
TGGATAATTTAAATCAACCTTGCCAACCATTCCAATTTGATGGTTCTCGCCAGAGAAAAATATTTTAAGGATTTGGACTA
TTATAGACTATAGAAGAAGT

Product: restriction endonuclease S subunits

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTEGPYKLPPGWRWVRLGEVCLPTERRDPTKNPSTYFVYVDISAIDSTVGKIVSPKEILGQHAPSRARKVIRSGDVIFAT
TRPYLKNIALVPPDLDGQICSTGFCVIRANREFAEPEFLFHLCRSDFITNQLTASKMRGTSYPAVTDNDVYNTLIPLPPL
EEQRRIVAKVEALMERVREVRRLRAEAQKDTELLMQTALAEVFPHPGADLPPGWRWVRLGEVCDIIMGQSPPSSTYNFEG
NGLPFFQGKADFGDLHPTPRIWCSAPQKVARPGDVLISVRAPVGSTNVANLACCIGRGLAALRPRDSLERFWLLYYLHYL
EPELSKMGAGSTFNAITKKDLQNVFIPLPPLEEQRRIVAYLDQIQQQVAALKRAQAETEAELKRLEQAILDKAFRGDL

Sequences:

>Translated_398_residues
MTEGPYKLPPGWRWVRLGEVCLPTERRDPTKNPSTYFVYVDISAIDSTVGKIVSPKEILGQHAPSRARKVIRSGDVIFAT
TRPYLKNIALVPPDLDGQICSTGFCVIRANREFAEPEFLFHLCRSDFITNQLTASKMRGTSYPAVTDNDVYNTLIPLPPL
EEQRRIVAKVEALMERVREVRRLRAEAQKDTELLMQTALAEVFPHPGADLPPGWRWVRLGEVCDIIMGQSPPSSTYNFEG
NGLPFFQGKADFGDLHPTPRIWCSAPQKVARPGDVLISVRAPVGSTNVANLACCIGRGLAALRPRDSLERFWLLYYLHYL
EPELSKMGAGSTFNAITKKDLQNVFIPLPPLEEQRRIVAYLDQIQQQVAALKRAQAETEAELKRLEQAILDKAFRGDL
>Mature_397_residues
TEGPYKLPPGWRWVRLGEVCLPTERRDPTKNPSTYFVYVDISAIDSTVGKIVSPKEILGQHAPSRARKVIRSGDVIFATT
RPYLKNIALVPPDLDGQICSTGFCVIRANREFAEPEFLFHLCRSDFITNQLTASKMRGTSYPAVTDNDVYNTLIPLPPLE
EQRRIVAKVEALMERVREVRRLRAEAQKDTELLMQTALAEVFPHPGADLPPGWRWVRLGEVCDIIMGQSPPSSTYNFEGN
GLPFFQGKADFGDLHPTPRIWCSAPQKVARPGDVLISVRAPVGSTNVANLACCIGRGLAALRPRDSLERFWLLYYLHYLE
PELSKMGAGSTFNAITKKDLQNVFIPLPPLEEQRRIVAYLDQIQQQVAALKRAQAETEAELKRLEQAILDKAFRGDL

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To M.jannaschii MJ0130 and MJ1218 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 44697; Mature: 44566

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGPYKLPPGWRWVRLGEVCLPTERRDPTKNPSTYFVYVDISAIDSTVGKIVSPKEILG
CCCCCCCCCCCCEEEEECCEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHH
QHAPSRARKVIRSGDVIFATTRPYLKNIALVPPDLDGQICSTGFCVIRANREFAEPEFLF
CCCCHHHHHHHHCCCEEEEECCHHHHCCEECCCCCCCCEECCCEEEEECCCCCCCHHHHH
HLCRSDFITNQLTASKMRGTSYPAVTDNDVYNTLIPLPPLEEQRRIVAKVEALMERVREV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRLRAEAQKDTELLMQTALAEVFPHPGADLPPGWRWVRLGEVCDIIMGQSPPSSTYNFEG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCC
NGLPFFQGKADFGDLHPTPRIWCSAPQKVARPGDVLISVRAPVGSTNVANLACCIGRGLA
CCCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCHH
ALRPRDSLERFWLLYYLHYLEPELSKMGAGSTFNAITKKDLQNVFIPLPPLEEQRRIVAY
HCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LDQIQQQVAALKRAQAETEAELKRLEQAILDKAFRGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TEGPYKLPPGWRWVRLGEVCLPTERRDPTKNPSTYFVYVDISAIDSTVGKIVSPKEILG
CCCCCCCCCCCEEEEECCEECCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCHHHHH
QHAPSRARKVIRSGDVIFATTRPYLKNIALVPPDLDGQICSTGFCVIRANREFAEPEFLF
CCCCHHHHHHHHCCCEEEEECCHHHHCCEECCCCCCCCEECCCEEEEECCCCCCCHHHHH
HLCRSDFITNQLTASKMRGTSYPAVTDNDVYNTLIPLPPLEEQRRIVAKVEALMERVREV
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
RRLRAEAQKDTELLMQTALAEVFPHPGADLPPGWRWVRLGEVCDIIMGQSPPSSTYNFEG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCC
NGLPFFQGKADFGDLHPTPRIWCSAPQKVARPGDVLISVRAPVGSTNVANLACCIGRGLA
CCCCCCCCCCCCCCCCCCCCEEECCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCHH
ALRPRDSLERFWLLYYLHYLEPELSKMGAGSTFNAITKKDLQNVFIPLPPLEEQRRIVAY
HCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LDQIQQQVAALKRAQAETEAELKRLEQAILDKAFRGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]