Click here to switch to the map view.

The map label for this gene is MesJ2 [H]

Identifier: 20807962

GI number: 20807962

Start: 1490304

End: 1491011

Strand: Reverse

Name: MesJ2 [H]

Synonym: TTE1527

Alternate gene names: 20807962

Gene position: 1491011-1490304 (Counterclockwise)

Preceding gene: 20807965

Following gene: 20807960

Centisome position: 55.44

GC content: 37.85

Gene sequence:

>708_bases
ATGCAGGAGATACTAGGCAAAATAAGAAGAGCGGTGCAGGACTTTGAGATGATACAGGAGGGAGATGCTATAGCTGTCGG
AGTGTCTGGAGGTAAAGACAGCATCACGCTTCTTTACGGATTACATCTTCTCAAAAGATTTTATCCAATAAAGTTCGAGG
TAATGGGACTCATGCTATCTTTAGGGTTTGAGAATTTCGACCCCACTCCTATAAAAAACTTCTGTGAAGAAAAGGGTATT
CCTTTTTTTGTTAAGCATACCGAAATAAAGAAAATCGTGTTTGACTACAGGAAAGAGAAAAATCCCTGCTCTTTATGCGC
AAATCTAAGGCGAGGTGCTCTGAATGACTTTGCAAAGGAGAAGGGTTGCAACAAAGTGGCTCTGGCACATCATTATGATG
ACTTGATAGTTACTTTTATGATGAATTTGTTTTACAATGGAAGACTTCACACTTTTGAACCTGTCACGTTTTTGGACAGG
TCTAAAATTACACTAATAAGGCCTTTGATTTATGTGAGAGAGAAGGAAGTGAGAAGTGCAGTGAAAAAAAACAACCTACC
TGTTGTGGAAAATCCGTGTCCTATGGCAGGGAATACTACTCGCCACTCAATTGAGAATTTGATTAGAAATTTAGAAAAAG
AAATCCCTGAATTGGACAAGAGAATTTTTACGGCCATAAAAAAAGATGTTTTTCAATTGAAAAATTGA

Upstream 100 bases:

>100_bases
CGGTTTTTGATAAGTTTTTTATACCACAGATGTCTTGATTTTGCAATTGTATATTGACATGGCAAAGAAAGCAGGATTAA
TATTTAGAGGGGTGATGAGT

Downstream 100 bases:

>100_bases
GTAAAAAAAAGCTTTGTGCAAAAATTGCGCAGGTTTTTAAGGATATTTCGACATAATTGAGATTTATTGGGGTTTATGGG
AGTTGAACCGATTTTTAAAA

Product: ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MQEILGKIRRAVQDFEMIQEGDAIAVGVSGGKDSITLLYGLHLLKRFYPIKFEVMGLMLSLGFENFDPTPIKNFCEEKGI
PFFVKHTEIKKIVFDYRKEKNPCSLCANLRRGALNDFAKEKGCNKVALAHHYDDLIVTFMMNLFYNGRLHTFEPVTFLDR
SKITLIRPLIYVREKEVRSAVKKNNLPVVENPCPMAGNTTRHSIENLIRNLEKEIPELDKRIFTAIKKDVFQLKN

Sequences:

>Translated_235_residues
MQEILGKIRRAVQDFEMIQEGDAIAVGVSGGKDSITLLYGLHLLKRFYPIKFEVMGLMLSLGFENFDPTPIKNFCEEKGI
PFFVKHTEIKKIVFDYRKEKNPCSLCANLRRGALNDFAKEKGCNKVALAHHYDDLIVTFMMNLFYNGRLHTFEPVTFLDR
SKITLIRPLIYVREKEVRSAVKKNNLPVVENPCPMAGNTTRHSIENLIRNLEKEIPELDKRIFTAIKKDVFQLKN
>Mature_235_residues
MQEILGKIRRAVQDFEMIQEGDAIAVGVSGGKDSITLLYGLHLLKRFYPIKFEVMGLMLSLGFENFDPTPIKNFCEEKGI
PFFVKHTEIKKIVFDYRKEKNPCSLCANLRRGALNDFAKEKGCNKVALAHHYDDLIVTFMMNLFYNGRLHTFEPVTFLDR
SKITLIRPLIYVREKEVRSAVKKNNLPVVENPCPMAGNTTRHSIENLIRNLEKEIPELDKRIFTAIKKDVFQLKN

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=224, Percent_Identity=34.8214285714286, Blast_Score=137, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI193211090, Length=234, Percent_Identity=29.9145299145299, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17540090, Length=220, Percent_Identity=25, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24651972, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 27123; Mature: 27123

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEILGKIRRAVQDFEMIQEGDAIAVGVSGGKDSITLLYGLHLLKRFYPIKFEVMGLMLS
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGFENFDPTPIKNFCEEKGIPFFVKHTEIKKIVFDYRKEKNPCSLCANLRRGALNDFAKE
HCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KGCNKVALAHHYDDLIVTFMMNLFYNGRLHTFEPVTFLDRSKITLIRPLIYVREKEVRSA
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
VKKNNLPVVENPCPMAGNTTRHSIENLIRNLEKEIPELDKRIFTAIKKDVFQLKN
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQEILGKIRRAVQDFEMIQEGDAIAVGVSGGKDSITLLYGLHLLKRFYPIKFEVMGLMLS
CHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGFENFDPTPIKNFCEEKGIPFFVKHTEIKKIVFDYRKEKNPCSLCANLRRGALNDFAKE
HCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
KGCNKVALAHHYDDLIVTFMMNLFYNGRLHTFEPVTFLDRSKITLIRPLIYVREKEVRSA
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHH
VKKNNLPVVENPCPMAGNTTRHSIENLIRNLEKEIPELDKRIFTAIKKDVFQLKN
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA