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The map label for this gene is frr [H]

Identifier: 20807853

GI number: 20807853

Start: 1389618

End: 1390172

Strand: Reverse

Name: frr [H]

Synonym: TTE1406

Alternate gene names: 20807853

Gene position: 1390172-1389618 (Counterclockwise)

Preceding gene: 20807854

Following gene: 20807852

Centisome position: 51.69

GC content: 40.72

Gene sequence:

>555_bases
ATGAGCGATTATTTGAAAGACAGTGAAGAGAGGATGAAGAAAACTTTAAACGTCTTAAAAAGCGAACTTGCGGCAATACG
TGCTGGAAGAGCGAATCCGGCCCTTTTAGACCGCATTACTGTGAATTACTACGGAACTCCTACTCCTTTAAACAGACTGG
CTACCATTACTGCGCCTGAGCCGAGGGTATTGGTAGTTCAACCGTGGGATGTATCTCAGATAGGAGAGATAGAAAAAGCC
ATACAGAAATCTGACCTAGGAATTAACCCTGTTTCTGACGGAAAAGTGCTAAGACTGGTCCTTCCAGAGCTTACAGAAGA
GAGAAGAAAAGAGCTTGTAAAGCTGGTCCACAAAAAAGCTGAAGAAGCCAGAATTGCTGTAAGGCAGATAAGAAGAGATG
CCAATGACCTTGTCAAAAAAATGGAAAAAGATGGAGAAATATCAGAAGACGAGAGAAAGAGAAGGGAAGAAGAAATTCAG
AAACTCACAGATAAATACATCAAGGAAATAGACAAAATGGTAGAGGCTAAAGAAAAGGAGATAATGGAAATTTGA

Upstream 100 bases:

>100_bases
AATAAAATCCCCATCATAGTGTTTGACCTGACCACATATGGAAACATTAAGAAAGTGGTAATGGGAAATGATATCGGTAC
GATTGTGAAGGAGGGTTAAC

Downstream 100 bases:

>100_bases
AGTATTACGACTTGATTGGAAGAGACCTTGAAGAGGTTCTTGATGCATTGTTCGGAAAAAAATGCAAAGTAGTAGAGACA
AAATCAATTTTCAGGTATGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPEPRVLVVQPWDVSQIGEIEKA
IQKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKAEEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQ
KLTDKYIKEIDKMVEAKEKEIMEI

Sequences:

>Translated_184_residues
MSDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPEPRVLVVQPWDVSQIGEIEKA
IQKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKAEEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQ
KLTDKYIKEIDKMVEAKEKEIMEI
>Mature_183_residues
SDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPEPRVLVVQPWDVSQIGEIEKAI
QKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKAEEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQK
LTDKYIKEIDKMVEAKEKEIMEI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=28.4916201117318, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=29.0540540540541, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=51.6304347826087, Blast_Score=188, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=26.5895953757225, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21230; Mature: 21099

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPE
CCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHEEEECCC
PRVLVVQPWDVSQIGEIEKAIQKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKA
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQKLTDKYIKEIDKMVEAKEKE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEI
HHCC
>Mature Secondary Structure 
SDYLKDSEERMKKTLNVLKSELAAIRAGRANPALLDRITVNYYGTPTPLNRLATITAPE
CCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHEEEECCC
PRVLVVQPWDVSQIGEIEKAIQKSDLGINPVSDGKVLRLVLPELTEERRKELVKLVHKKA
CCEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EEARIAVRQIRRDANDLVKKMEKDGEISEDERKRREEEIQKLTDKYIKEIDKMVEAKEKE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMEI
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA