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The map label for this gene is PgsA2 [H]

Identifier: 20807823

GI number: 20807823

Start: 1359028

End: 1359564

Strand: Reverse

Name: PgsA2 [H]

Synonym: TTE1376

Alternate gene names: 20807823

Gene position: 1359564-1359028 (Counterclockwise)

Preceding gene: 20807824

Following gene: 20807822

Centisome position: 50.55

GC content: 36.5

Gene sequence:

>537_bases
ATGAACCTAGCTAATAAACTGACTATGTCGCGACTTTTTTTAATACCCGTCTTTATGGTATTTATGCTGGTAAAAATTCC
GTATGGAGATTTCATAGCTGCTTCTATTTTTGCCATTGGGGCTTTAACTGACAAGTTGGACGGGTATATTGCAAGAAAAT
ATAAACAAATAACAAACTTTGGCAAATTTATGGACCCTTTGGTTGACAAAATAATGGTCACTTCTGCTCTAATTGCCTTA
GTTCAGATGGGAAGGATTGAAAGCTGGATAGTCATAGTCATAATTGCAAGAGAGTTTCTAATCACTGGCATAAGGACAGT
CGCTGCAGACAAAGGAATTGTAATAGCAGCAAGTAACTACGGAAAATACAAGACGACTTCTCAGATGATTGCAGTTATCG
CTTTGATGCTGAACAATTATCCTTTTAGCCTTGTCAACTTCCCATTTGACAAGATAATGGTGTATATAGCGCTAATTTTG
ACAATTTACTCGGGTGTGGACTACATTGTAAAATCAAAAGACCTTTTTAAGGATTGA

Upstream 100 bases:

>100_bases
GTCTTGTATATGTGAGAAGCGACAAAAAACTCTTTCCAGGCGATTTTGTTACAGTAACAGTAGTAGATGCGTTTGAATAC
GACCTTGTGGGGGAATATTG

Downstream 100 bases:

>100_bases
AAAAGAGGTGTTTGTATGAGAGGAGAAATAATTTCTGTAGGCACAGAGCTTTTATTAGGGCAAATTGTAAATACAAATGC
CAAGTATCTATCTGAAAGAC

Product: phosphatidylglycerophosphate synthase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MNLANKLTMSRLFLIPVFMVFMLVKIPYGDFIAASIFAIGALTDKLDGYIARKYKQITNFGKFMDPLVDKIMVTSALIAL
VQMGRIESWIVIVIIAREFLITGIRTVAADKGIVIAASNYGKYKTTSQMIAVIALMLNNYPFSLVNFPFDKIMVYIALIL
TIYSGVDYIVKSKDLFKD

Sequences:

>Translated_178_residues
MNLANKLTMSRLFLIPVFMVFMLVKIPYGDFIAASIFAIGALTDKLDGYIARKYKQITNFGKFMDPLVDKIMVTSALIAL
VQMGRIESWIVIVIIAREFLITGIRTVAADKGIVIAASNYGKYKTTSQMIAVIALMLNNYPFSLVNFPFDKIMVYIALIL
TIYSGVDYIVKSKDLFKD
>Mature_178_residues
MNLANKLTMSRLFLIPVFMVFMLVKIPYGDFIAASIFAIGALTDKLDGYIARKYKQITNFGKFMDPLVDKIMVTSALIAL
VQMGRIESWIVIVIIAREFLITGIRTVAADKGIVIAASNYGKYKTTSQMIAVIALMLNNYPFSLVNFPFDKIMVYIALIL
TIYSGVDYIVKSKDLFKD

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=178, Percent_Identity=33.7078651685393, Blast_Score=104, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24650130, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650126, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24650128, Length=200, Percent_Identity=25.5, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19988; Mature: 19988

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLANKLTMSRLFLIPVFMVFMLVKIPYGDFIAASIFAIGALTDKLDGYIARKYKQITNF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFMDPLVDKIMVTSALIALVQMGRIESWIVIVIIAREFLITGIRTVAADKGIVIAASNY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GKYKTTSQMIAVIALMLNNYPFSLVNFPFDKIMVYIALILTIYSGVDYIVKSKDLFKD
CCHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHCCHHHCCC
>Mature Secondary Structure
MNLANKLTMSRLFLIPVFMVFMLVKIPYGDFIAASIFAIGALTDKLDGYIARKYKQITNF
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKFMDPLVDKIMVTSALIALVQMGRIESWIVIVIIAREFLITGIRTVAADKGIVIAASNY
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
GKYKTTSQMIAVIALMLNNYPFSLVNFPFDKIMVYIALILTIYSGVDYIVKSKDLFKD
CCHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHCHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]