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The map label for this gene is 20807819

Identifier: 20807819

GI number: 20807819

Start: 1354462

End: 1356033

Strand: Reverse

Name: 20807819

Synonym: TTE1372

Alternate gene names: NA

Gene position: 1356033-1354462 (Counterclockwise)

Preceding gene: 20807820

Following gene: 20807818

Centisome position: 50.42

GC content: 41.16

Gene sequence:

>1572_bases
ATGAATCATCTACTAAGGAGGTGTAGGAGTATAAGCTATGTTGGATTGATAATCACAGCACTTATTGCAATACTAATCGG
CTTTCTAGCAGGTTTTCTGGCACGCAAAGTCATTGCAGAGTCTAAAATAAAAAGTGCCGAAAACCTGGCGCGGACTATTC
TAGAAAGCGCTAAGAAGGACGCTGAGAATAAAAAGAGAGAAGCCTTACTGGAAGCCAAAGAAGAAATTCACCGCTTAAGA
TCCGATTTTGAAAAAGAAGTAAGAGACAGAAGAGGAGAGCTCCAAAGACTTGAAAAAAGGCTTCTCCAAAAAGAAGAGAT
ACTTGAAAAAAGAGCCGAAAGTCTCGAACAAAAAGAAATCTTATTAGAACAAAAGCAAAAAGAAATTCAACAGCTAGAAG
AACAAATAACTCTGCTTCACAAAAAACAACTGGAGGAATTGGAAAGAATCTCCGGTCTTACTCAGGAAGAAGCGAAAAGT
ATACTGTTAGAAAGTGTACAGAAAGAAATACAGCATGACATGGCAGTAATGATTAAAGAAATGGAAAACAAAGCCAAAGA
AGAAGCAGACAGAAGAGCAAGAGAAATCGTGGGATTAGCTATACAGCGATGTGCCGCTGACCATGCGGCAGAAACAACTG
TTTCAGTAGTTACACTGCCCAACGATGAGATGAAAGGACGCATTATTGGAAGAGAAGGTAGAAACATAAGGACAATTGAA
ACTCTTACAGGAATTGACCTAATAATTGACGATACACCTGAGGCAGTAGTAATCTCTGGTTTTGACCCGATAAGAAGAGA
AATAGCGAGAATTGCCCTTGAGAAGTTGATTGAAGATGGCAGAATACACCCAGCAAGGATAGAGGAAATGGTAGAAAAAG
CCAAGAAGGAAGTAGACAACATGATAATAAAGGCTGGAGAAGAAGCGGCTTTTGAAGTAGGCGTACACGGATTGCACCCT
GAACTCATAAAACTTCTGGGAAGACTCAAATTCAGAACTAGCTATGGTCAAAATGTTCTCAAGCATTCCATAGAAGTTGC
TCATCTTGCTGGGCTTATGGCTTATGAATTAGGGGCAGATGCCTCAATTGCTAAAAGAGCAGGGCTTTTGCACGACATAG
GAAAGGCTGTAGACCATGAAGTGGAAGGCCCTCACGTGATGATAGGTGCAGAGCTTGCAAAAAGATATCACGAGTCTGAC
GCAGTGGTACATGCGATTATGGCTCATCACAATGATGTTGAGCCTCAAACGATTGAAGCAGTTCTGGTTCAGGCAGCTGA
TGCGATTTCGGCGGCCAGACCGGGTGCAAGGCGGGAGGCTTTAGAGGCTTATATAAAGAGGCTTGATAAGTTAGAGCAAA
TTGCTAATTCTTTTGAAGGCGTGGAAAAAGCTTATGCTATTCAGGCAGGAAGAGAAATAAGGATAATGGTAAAACCTGAG
GCTATAAGCGATGACGAACTTGTGATATTGGCTAGAAATATAAGCAAGAAGATTGAAGAAGAAGTGGAATATCCTGGACA
GATTAAAGTGACAGTCATAAGGGAGACGGTGGCTATTGATTATGCAAAATAA

Upstream 100 bases:

>100_bases
CAAAAATTAAAAAAATATCTCTATACCAATGGCTTTGAAATTGAAAATATTGAAAAGGCATTGAACTTGACATAATTTTG
TAAAGGGTCTAAAATAGAAT

Downstream 100 bases:

>100_bases
AGATTTTGAAAAAAAGCGTGCGTTTCGCACGCTTTAAAAGTTTATAAATTTGTGCAATAATAATTGGTAGGAGTTTTTCT
AAAAAATTTTACTCGGAGGT

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKDAENKKREALLEAKEEIHRLR
SDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEILLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKS
ILLESVQKEIQHDMAVMIKEMENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIE
TLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDNMIIKAGEEAAFEVGVHGLHP
ELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGADASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESD
AVVHAIMAHHNDVEPQTIEAVLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPE
AISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK

Sequences:

>Translated_523_residues
MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKDAENKKREALLEAKEEIHRLR
SDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEILLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKS
ILLESVQKEIQHDMAVMIKEMENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIE
TLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDNMIIKAGEEAAFEVGVHGLHP
ELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGADASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESD
AVVHAIMAHHNDVEPQTIEAVLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPE
AISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK
>Mature_523_residues
MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKDAENKKREALLEAKEEIHRLR
SDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEILLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKS
ILLESVQKEIQHDMAVMIKEMENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIE
TLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDNMIIKAGEEAAFEVGVHGLHP
ELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGADASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESD
AVVHAIMAHHNDVEPQTIEAVLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPE
AISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CNPD_THETN (Q8RA57)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622990.1
- ProteinModelPortal:   Q8RA57
- GeneID:   996718
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1372
- NMPDR:   fig|273068.3.peg.180
- HOGENOM:   HBG734610
- OMA:   HPGRIEE
- ProtClustDB:   PRK12704
- BioCyc:   TTEN273068:TTE1372-MONOMER
- HAMAP:   MF_00335
- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675
- SMART:   SM00471
- SMART:   SM00322
- TIGRFAMs:   TIGR00277
- TIGRFAMs:   TIGR03319

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1

EC number: =3.1.4.16

Molecular weight: Translated: 58898; Mature: 58898

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbb58ea8)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKD
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENKKREALLEAKEEIHRLRSDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKSILLESVQKEIQHDMAVMIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEECCCCCCEEEEH
TLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDN
HHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MIIKAGEEAAFEVGVHGLHPELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGAD
HHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESDAVVHAIMAHHNDVEPQTIEA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK
CCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCH
>Mature Secondary Structure
MNHLLRRCRSISYVGLIITALIAILIGFLAGFLARKVIAESKIKSAENLARTILESAKKD
CCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AENKKREALLEAKEEIHRLRSDFEKEVRDRRGELQRLEKRLLQKEEILEKRAESLEQKEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLEQKQKEIQQLEEQITLLHKKQLEELERISGLTQEEAKSILLESVQKEIQHDMAVMIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MENKAKEEADRRAREIVGLAIQRCAADHAAETTVSVVTLPNDEMKGRIIGREGRNIRTIE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEECCCCCCEEEEH
TLTGIDLIIDDTPEAVVISGFDPIRREIARIALEKLIEDGRIHPARIEEMVEKAKKEVDN
HHCCCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MIIKAGEEAAFEVGVHGLHPELIKLLGRLKFRTSYGQNVLKHSIEVAHLAGLMAYELGAD
HHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASIAKRAGLLHDIGKAVDHEVEGPHVMIGAELAKRYHESDAVVHAIMAHHNDVEPQTIEA
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VLVQAADAISAARPGARREALEAYIKRLDKLEQIANSFEGVEKAYAIQAGREIRIMVKPE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCC
AISDDELVILARNISKKIEEEVEYPGQIKVTVIRETVAIDYAK
CCCCCCEEEEHHHHHHHHHHHHCCCCCEEEEEEEHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336