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The map label for this gene is xerC

Identifier: 20807810

GI number: 20807810

Start: 1345336

End: 1346397

Strand: Direct

Name: xerC

Synonym: TTE1363

Alternate gene names: 20807810

Gene position: 1345336-1346397 (Clockwise)

Preceding gene: 20807809

Following gene: 20807812

Centisome position: 50.02

GC content: 35.4

Gene sequence:

>1062_bases
GTGCTTGATTTTTCCTTGTTTGTGTGGTACCATAGATTATGTAATTATACGAAATATCTATTTCGTATAATTAGATTTTG
GACTATAAAAAGAAAGGAGCTTTCATTTATGGAGGCTTTAAAGTATCCCCCTATATTGGAAGAGTTTCTGAACTACTTCT
CCACTGTAAAAGCCAGGTCACCTAATACTATAAAGGCTTACGCTTATGACCTTATTTTATTTTTCCGCTTTTTAAAGAAA
AGGCGCGGAAAAGTAAGCGATGATATTCCCTTTGATGAAATAGACATTTCTGACGTTGATATTGACCTTATAGAGTCTGT
TGATTTAAACGACCTTTATGCCTATCTTTCTTTTGTGACAAATGAAAGGTCTAATACTCCCCCTGCTCGCGCAAGAAAAG
TTGCAAGTCTAAGGTCTTTTTACAATTACCTTTACAGAAAAGCAAAAGTCATAAGTAAAAATCCTACACAGGAATTAGAA
TCTCCTAAACTTTCAGTAAGGCATCCTATTTATCTGACCTTAGAAGAAAGCAAAAAGCTTTTAAACTCTATAGATGGTCC
TTTTAAGGAAAGAGATTACGCTATTATAACTCTTTTTCTAAACTGTGGTTTAAGGGTTTCAGAGCTTGTAAATATAAATC
TTGATGATATAAAAGAAGACAAATTGACTGTCATAGGAAAAGGAAATAAGCAGCGGACTATCTACCTAAATGAGGCTTGT
ATAAAGGCTATAAGCGATTACCTCAAAGTAAGGCCCAAAGAAGGCGTGAAAGACAAAAAGGCCCTGTTTTTGAGTAAAAG
ACTGAAGAGGATAAGCGTAAAAACTGTTCAATACTTGGTTAAAAAGCATTTAAAACATGCTAATTTAGAAGGCAAGAAAT
ACTCTGCTCACAAACTTCGCCACACAGCAGCTACTTTAATGTACAGGTACGGAAACGTAGATATACGTACATTGCAAAAG
CTTTTGGGGCATTCTAACGTTTCAACCACGCAGATTTACACACATGTGGACGACTCACAGCTTAGAGAGGCTGTGAATAA
AAACCCCTTATCTCAAGAATAA

Upstream 100 bases:

>100_bases
GATAATGAGTACAACAACTTGTGCGACAGACTGGCCACAGAACAAATAAAAAAACACATAAAAGAGAATCCCTAAGTTTT
GGGATTCTCTTTTAGTTTTT

Downstream 100 bases:

>100_bases
ATTCTGCTGAGAGCTATGGATATGGCCAATTTAACTTGAGGATAACTCAAGCCTCCCTGTACATAGGCAGTATAAGGCTC
TCTTATAGGCGCATCGGCGC

Product: site-specific tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLDFSLFVWYHRLCNYTKYLFRIIRFWTIKRKELSFMEALKYPPILEEFLNYFSTVKARSPNTIKAYAYDLILFFRFLKK
RRGKVSDDIPFDEIDISDVDIDLIESVDLNDLYAYLSFVTNERSNTPPARARKVASLRSFYNYLYRKAKVISKNPTQELE
SPKLSVRHPIYLTLEESKKLLNSIDGPFKERDYAIITLFLNCGLRVSELVNINLDDIKEDKLTVIGKGNKQRTIYLNEAC
IKAISDYLKVRPKEGVKDKKALFLSKRLKRISVKTVQYLVKKHLKHANLEGKKYSAHKLRHTAATLMYRYGNVDIRTLQK
LLGHSNVSTTQIYTHVDDSQLREAVNKNPLSQE

Sequences:

>Translated_353_residues
MLDFSLFVWYHRLCNYTKYLFRIIRFWTIKRKELSFMEALKYPPILEEFLNYFSTVKARSPNTIKAYAYDLILFFRFLKK
RRGKVSDDIPFDEIDISDVDIDLIESVDLNDLYAYLSFVTNERSNTPPARARKVASLRSFYNYLYRKAKVISKNPTQELE
SPKLSVRHPIYLTLEESKKLLNSIDGPFKERDYAIITLFLNCGLRVSELVNINLDDIKEDKLTVIGKGNKQRTIYLNEAC
IKAISDYLKVRPKEGVKDKKALFLSKRLKRISVKTVQYLVKKHLKHANLEGKKYSAHKLRHTAATLMYRYGNVDIRTLQK
LLGHSNVSTTQIYTHVDDSQLREAVNKNPLSQE
>Mature_353_residues
MLDFSLFVWYHRLCNYTKYLFRIIRFWTIKRKELSFMEALKYPPILEEFLNYFSTVKARSPNTIKAYAYDLILFFRFLKK
RRGKVSDDIPFDEIDISDVDIDLIESVDLNDLYAYLSFVTNERSNTPPARARKVASLRSFYNYLYRKAKVISKNPTQELE
SPKLSVRHPIYLTLEESKKLLNSIDGPFKERDYAIITLFLNCGLRVSELVNINLDDIKEDKLTVIGKGNKQRTIYLNEAC
IKAISDYLKVRPKEGVKDKKALFLSKRLKRISVKTVQYLVKKHLKHANLEGKKYSAHKLRHTAATLMYRYGNVDIRTLQK
LLGHSNVSTTQIYTHVDDSQLREAVNKNPLSQE

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=305, Percent_Identity=34.0983606557377, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790244, Length=302, Percent_Identity=30.1324503311258, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_THETN (Q8RA66)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622981.1
- ProteinModelPortal:   Q8RA66
- SMR:   Q8RA66
- GeneID:   997778
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1363
- NMPDR:   fig|273068.3.peg.122
- HOGENOM:   HBG727654
- OMA:   TLFLNCG
- ProtClustDB:   PRK00236
- BioCyc:   TTEN273068:TTE1363-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 41372; Mature: 41372

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: ACT_SITE 205-205 ACT_SITE 227-227 ACT_SITE 297-297 ACT_SITE 300-300 ACT_SITE 324-324 ACT_SITE 333-333

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDFSLFVWYHRLCNYTKYLFRIIRFWTIKRKELSFMEALKYPPILEEFLNYFSTVKARS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PNTIKAYAYDLILFFRFLKKRRGKVSDDIPFDEIDISDVDIDLIESVDLNDLYAYLSFVT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
NERSNTPPARARKVASLRSFYNYLYRKAKVISKNPTQELESPKLSVRHPIYLTLEESKKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECCCEEEEEHHHHHH
LNSIDGPFKERDYAIITLFLNCGLRVSELVNINLDDIKEDKLTVIGKGNKQRTIYLNEAC
HHHCCCCCCCCCCEEEEEEHHCCCCHHHHEECCHHHCCCCCEEEEECCCCCEEEEECHHH
IKAISDYLKVRPKEGVKDKKALFLSKRLKRISVKTVQYLVKKHLKHANLEGKKYSAHKLR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
HTAATLMYRYGNVDIRTLQKLLGHSNVSTTQIYTHVDDSQLREAVNKNPLSQE
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLDFSLFVWYHRLCNYTKYLFRIIRFWTIKRKELSFMEALKYPPILEEFLNYFSTVKARS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCC
PNTIKAYAYDLILFFRFLKKRRGKVSDDIPFDEIDISDVDIDLIESVDLNDLYAYLSFVT
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHH
NERSNTPPARARKVASLRSFYNYLYRKAKVISKNPTQELESPKLSVRHPIYLTLEESKKL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECCCEEEEEHHHHHH
LNSIDGPFKERDYAIITLFLNCGLRVSELVNINLDDIKEDKLTVIGKGNKQRTIYLNEAC
HHHCCCCCCCCCCEEEEEEHHCCCCHHHHEECCHHHCCCCCEEEEECCCCCEEEEECHHH
IKAISDYLKVRPKEGVKDKKALFLSKRLKRISVKTVQYLVKKHLKHANLEGKKYSAHKLR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
HTAATLMYRYGNVDIRTLQKLLGHSNVSTTQIYTHVDDSQLREAVNKNPLSQE
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336