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The map label for this gene is SpeB [H]

Identifier: 20807782

GI number: 20807782

Start: 1319639

End: 1320520

Strand: Direct

Name: SpeB [H]

Synonym: TTE1335

Alternate gene names: 20807782

Gene position: 1319639-1320520 (Clockwise)

Preceding gene: 20807781

Following gene: 20807783

Centisome position: 49.07

GC content: 37.64

Gene sequence:

>882_bases
TTGATGAGGTGTAAAATGGGAGAGAGAGTAAATTTCATAGATACAGGAAAGTTTTTAACCGCTACTAAGGAATATGAGGA
GGCAGACATTGTCTTGGTAGGGGTACCTATGGATTACAGCGTCAGCTTTAAGCCTGGTACCCGCTTTGGTCCTTCTTCTA
TAAGGCAGGCCTCCTATGGGCTTGAAACTTACAGCGTTTACCTTGACAGGCGCTTAGAAGACAAAAAAATATGTGATTTG
GGAGATTTGGTGCTGCCTTATGGAAATATAGAGAAAAGCTTGAGATTAATTGAGGAAGTTGCTGAAAAAATAGTCAAAGA
TGGAAAAAAGGGCATTTTCTTAGGCGGAGAGCATTTGATTACTTATGGGATTTTAAAAAGTTATATAAAAAAATACGGAG
ATAAGTTGGCTATTTTACACTTTGACGCTCACACAGACCTAAGAGAAGAATTTTTTGATGAGCCCTATTCCCACGCTACT
GTATTAAGAAAAGTATGGGAACTAAGCCCTAAAGTTAAAATATATCACTTTGGCATAAGGTCTGGAGAAAAAGAGGAGTT
TGAATTTGCCGAAAAAAATACAAATATGTTTTTGTATGAGGTGGTAGAACCTCTAAAAAATGTGATGAAGGAGATAAAAG
AAAATTTTATATACATAACCTTTGATATAGACGTATTAGATCCTGCTTTTGCACCAGGGACTGGAACGCCAGAACCCGGT
GGGATAACGGCAAAAGAGGCCTTAGAAGCCATCCACCTTTTAAAAGATTTTAATGTGATAGGGATGGATTTAGTAGAAGT
ATCTCCTCCTTATGACGTCGCAGGTATTACATCTATACTTGCGGCAAAACTTGTAAGAGAAGCTATTCTCTCTTTCTTTT
AA

Upstream 100 bases:

>100_bases
GAAGTCGATATAAATTCTATACCTAGAATTCAAACCAAGTATTATACACCGGAAATCCATAAGGCGGCTTTTGTGCTTCC
TAAATTTGTAAAAGATATTT

Downstream 100 bases:

>100_bases
GTTTGGGGCCAAAAAGGCCTTTTTTTATTTTGACTTTTTTAGTATAATATATTAGGAGGAGGTATTAATATGAGCAATAA
AGTTAAAATAACAGAAACAG

Product: arginase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MMRCKMGERVNFIDTGKFLTATKEYEEADIVLVGVPMDYSVSFKPGTRFGPSSIRQASYGLETYSVYLDRRLEDKKICDL
GDLVLPYGNIEKSLRLIEEVAEKIVKDGKKGIFLGGEHLITYGILKSYIKKYGDKLAILHFDAHTDLREEFFDEPYSHAT
VLRKVWELSPKVKIYHFGIRSGEKEEFEFAEKNTNMFLYEVVEPLKNVMKEIKENFIYITFDIDVLDPAFAPGTGTPEPG
GITAKEALEAIHLLKDFNVIGMDLVEVSPPYDVAGITSILAAKLVREAILSFF

Sequences:

>Translated_293_residues
MMRCKMGERVNFIDTGKFLTATKEYEEADIVLVGVPMDYSVSFKPGTRFGPSSIRQASYGLETYSVYLDRRLEDKKICDL
GDLVLPYGNIEKSLRLIEEVAEKIVKDGKKGIFLGGEHLITYGILKSYIKKYGDKLAILHFDAHTDLREEFFDEPYSHAT
VLRKVWELSPKVKIYHFGIRSGEKEEFEFAEKNTNMFLYEVVEPLKNVMKEIKENFIYITFDIDVLDPAFAPGTGTPEPG
GITAKEALEAIHLLKDFNVIGMDLVEVSPPYDVAGITSILAAKLVREAILSFF
>Mature_293_residues
MMRCKMGERVNFIDTGKFLTATKEYEEADIVLVGVPMDYSVSFKPGTRFGPSSIRQASYGLETYSVYLDRRLEDKKICDL
GDLVLPYGNIEKSLRLIEEVAEKIVKDGKKGIFLGGEHLITYGILKSYIKKYGDKLAILHFDAHTDLREEFFDEPYSHAT
VLRKVWELSPKVKIYHFGIRSGEKEEFEFAEKNTNMFLYEVVEPLKNVMKEIKENFIYITFDIDVLDPAFAPGTGTPEPG
GITAKEALEAIHLLKDFNVIGMDLVEVSPPYDVAGITSILAAKLVREAILSFF

Specific function: Catalyzes the formation of putrescine from agmatine [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=286, Percent_Identity=38.1118881118881, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI4502215, Length=307, Percent_Identity=25.7328990228013, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1789306, Length=262, Percent_Identity=35.8778625954198, Blast_Score=158, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6325146, Length=212, Percent_Identity=28.3018867924528, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24638886, Length=298, Percent_Identity=25.1677852348993, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 33206; Mature: 33206

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRCKMGERVNFIDTGKFLTATKEYEEADIVLVGVPMDYSVSFKPGTRFGPSSIRQASYG
CCCCCCCCCCCEEECCCEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHCC
LETYSVYLDRRLEDKKICDLGDLVLPYGNIEKSLRLIEEVAEKIVKDGKKGIFLGGEHLI
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHH
TYGILKSYIKKYGDKLAILHFDAHTDLREEFFDEPYSHATVLRKVWELSPKVKIYHFGIR
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCC
SGEKEEFEFAEKNTNMFLYEVVEPLKNVMKEIKENFIYITFDIDVLDPAFAPGTGTPEPG
CCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCC
GITAKEALEAIHLLKDFNVIGMDLVEVSPPYDVAGITSILAAKLVREAILSFF
CCCHHHHHHHHHHHHCCCEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMRCKMGERVNFIDTGKFLTATKEYEEADIVLVGVPMDYSVSFKPGTRFGPSSIRQASYG
CCCCCCCCCCCEEECCCEEEECCCCCCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHCC
LETYSVYLDRRLEDKKICDLGDLVLPYGNIEKSLRLIEEVAEKIVKDGKKGIFLGGEHLI
CHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCHHHH
TYGILKSYIKKYGDKLAILHFDAHTDLREEFFDEPYSHATVLRKVWELSPKVKIYHFGIR
HHHHHHHHHHHHCCEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCC
SGEKEEFEFAEKNTNMFLYEVVEPLKNVMKEIKENFIYITFDIDVLDPAFAPGTGTPEPG
CCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCCC
GITAKEALEAIHLLKDFNVIGMDLVEVSPPYDVAGITSILAAKLVREAILSFF
CCCHHHHHHHHHHHHCCCEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]