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The map label for this gene is XerC [C]

Identifier: 20807762

GI number: 20807762

Start: 1303737

End: 1304609

Strand: Direct

Name: XerC [C]

Synonym: TTE1313

Alternate gene names: 20807762

Gene position: 1303737-1304609 (Clockwise)

Preceding gene: 20807761

Following gene: 20807763

Centisome position: 48.48

GC content: 35.85

Gene sequence:

>873_bases
ATGGCTGAAAGCGTGGTTGGGGAGTTTTTGGAGTTTTTAAAGAAAAATAAAAGGCTATCTAAAAATACATTAGAGTCCTA
TTCCAGAGATGTAGAACAATTTTTAACTTACATGAATGAACATGGGATAAATTTTTGTTCTGCTAAAAAGTCCACCATTG
TAAATTACCTTTATTTTCTAAAACAGCAGGGAAAATCCCAGGCTACCATATCTAGAGCTCTTTCTTCAATAAAAGCTTTT
TATCACTATTTGTTTGCTAAGAAAAAAATTGAGGAAGACCCCTCTTATGGTATAAATGCCCCCAAAGTAGAAAAAAAGGA
GCCTGTTACCTTGACAGTAGAACAAGTAGATATGCTTTTATCTTTTGATTTTGGTAAAGATGAGAAAGGGTTGAGAGATA
AAGCGTTGATAGAATTGATGTACGCTTCCGGCCTTAAAGTCTCTGAAGTGATATCTTTGAAGATAGAGGATGTAAATTTG
GCCAGTGGCTACATTGTAGTGCGCTCTGGAAAAGAAAGGGTTATTCCTATAGGTTCTTACGCAGTTGCTGCACTTCAGGA
ATATATTGAAAAAGGAAGAAAACCCAGAAAAGGAGAAAAAGCCCTTTTTCTCAATTTGAGAGGGAAAAGGCTTACAAGGC
AGGGATGTTGGAAGATAATAAAAGAATACGCTGACAAAATAAGTCCGGGTTTGCCTTTAACTCCAAACATTTTGAGAAAA
TCTTTTGCCCAGCACATGCTTCAAAATGGAGCGGATTTAAAGACTGTCCAAGAGATGCTGGGATATGAAGTAAATTTTGG
AAATAATTTACTTTCTCTGGTTTCGCGGTCAAAAATGAAAGAAGTTTACAATAAATTTCATCCAAGAGCTTGA

Upstream 100 bases:

>100_bases
TCTTCCTATTTTTTCGCTGTAGAAAAGAAGGAAATTGACGATTTATGTTGAATATTTATAATTAATGAACTTATATAGAA
AATTGTAGGGGTAAAAGGGT

Downstream 100 bases:

>100_bases
AAAGGCATAAAATTCACCCTCCGGTACACAATATAAAATAGCAACGAAGGAGGGTGAATTTTTATGTCAAAAAAGTTTTT
AGCATTATTGATAAGCACAT

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MAESVVGEFLEFLKKNKRLSKNTLESYSRDVEQFLTYMNEHGINFCSAKKSTIVNYLYFLKQQGKSQATISRALSSIKAF
YHYLFAKKKIEEDPSYGINAPKVEKKEPVTLTVEQVDMLLSFDFGKDEKGLRDKALIELMYASGLKVSEVISLKIEDVNL
ASGYIVVRSGKERVIPIGSYAVAALQEYIEKGRKPRKGEKALFLNLRGKRLTRQGCWKIIKEYADKISPGLPLTPNILRK
SFAQHMLQNGADLKTVQEMLGYEVNFGNNLLSLVSRSKMKEVYNKFHPRA

Sequences:

>Translated_290_residues
MAESVVGEFLEFLKKNKRLSKNTLESYSRDVEQFLTYMNEHGINFCSAKKSTIVNYLYFLKQQGKSQATISRALSSIKAF
YHYLFAKKKIEEDPSYGINAPKVEKKEPVTLTVEQVDMLLSFDFGKDEKGLRDKALIELMYASGLKVSEVISLKIEDVNL
ASGYIVVRSGKERVIPIGSYAVAALQEYIEKGRKPRKGEKALFLNLRGKRLTRQGCWKIIKEYADKISPGLPLTPNILRK
SFAQHMLQNGADLKTVQEMLGYEVNFGNNLLSLVSRSKMKEVYNKFHPRA
>Mature_289_residues
AESVVGEFLEFLKKNKRLSKNTLESYSRDVEQFLTYMNEHGINFCSAKKSTIVNYLYFLKQQGKSQATISRALSSIKAFY
HYLFAKKKIEEDPSYGINAPKVEKKEPVTLTVEQVDMLLSFDFGKDEKGLRDKALIELMYASGLKVSEVISLKIEDVNLA
SGYIVVRSGKERVIPIGSYAVAALQEYIEKGRKPRKGEKALFLNLRGKRLTRQGCWKIIKEYADKISPGLPLTPNILRKS
FAQHMLQNGADLKTVQEMLGYEVNFGNNLLSLVSRSKMKEVYNKFHPRA

Specific function: Potential site-specific tyrosine recombinase, which may act by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregatio

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=32.7645051194539, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1790244, Length=288, Percent_Identity=30.5555555555556, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790768, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERDL_THETN (Q8RAB1)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622933.1
- ProteinModelPortal:   Q8RAB1
- SMR:   Q8RAB1
- GeneID:   997695
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE1313
- NMPDR:   fig|273068.3.peg.1253
- HOGENOM:   HBG727654
- OMA:   DTQARSV
- ProtClustDB:   CLSK901165
- BioCyc:   TTEN273068:TTE1313-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01807
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10
- TIGRFAMs:   TIGR02225

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 33026; Mature: 32895

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESVVGEFLEFLKKNKRLSKNTLESYSRDVEQFLTYMNEHGINFCSAKKSTIVNYLYFL
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KQQGKSQATISRALSSIKAFYHYLFAKKKIEEDPSYGINAPKVEKKEPVTLTVEQVDMLL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
SFDFGKDEKGLRDKALIELMYASGLKVSEVISLKIEDVNLASGYIVVRSGKERVIPIGSY
HCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHEEEEECEEEECCEEEEECCCCCEEECHHH
AVAALQEYIEKGRKPRKGEKALFLNLRGKRLTRQGCWKIIKEYADKISPGLPLTPNILRK
HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SFAQHMLQNGADLKTVQEMLGYEVNFGNNLLSLVSRSKMKEVYNKFHPRA
HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AESVVGEFLEFLKKNKRLSKNTLESYSRDVEQFLTYMNEHGINFCSAKKSTIVNYLYFL
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
KQQGKSQATISRALSSIKAFYHYLFAKKKIEEDPSYGINAPKVEKKEPVTLTVEQVDMLL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEHHHHHHHH
SFDFGKDEKGLRDKALIELMYASGLKVSEVISLKIEDVNLASGYIVVRSGKERVIPIGSY
HCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHEEEEECEEEECCEEEEECCCCCEEECHHH
AVAALQEYIEKGRKPRKGEKALFLNLRGKRLTRQGCWKIIKEYADKISPGLPLTPNILRK
HHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
SFAQHMLQNGADLKTVQEMLGYEVNFGNNLLSLVSRSKMKEVYNKFHPRA
HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336