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The map label for this gene is rnjA [H]

Identifier: 20807702

GI number: 20807702

Start: 1252767

End: 1254431

Strand: Direct

Name: rnjA [H]

Synonym: TTE1253

Alternate gene names: 20807702

Gene position: 1252767-1254431 (Clockwise)

Preceding gene: 20807701

Following gene: 20807703

Centisome position: 46.58

GC content: 43.24

Gene sequence:

>1665_bases
TTGGCGCACAAGGCAAAACTGAAGATAATTCCTTTGGGCGGATTAAATGAAATTGGCAAAAACATGACTGTATTCGAGTA
TGGAAATGATATCATAGTTGTAGACTGTGGCCTCGCTTTCCCTGATGATGAGATGTTAGGAATTGACCTTGTCATTCCCG
ATATTACTTATTTATTGAAAAACAGGGAAAAAGTTAAAGCAATTGTGCTCACCCATGGCCACGAGGACCACATAGGGGCT
CTGCCCTACGTGTTGAAGCAGCTCAATGTTCCAATTTATGGTACCAGACTTACAATTGGGTTGGTTGAGTACAAATTAAA
AGAGCACGGACTTTTGAGAGACAGTAAGCTAATCACTGTAAAACCCAGAGAGACAGTTGAGATCGGCCAGTTTAAAGTAG
AGTTTATAAGGACTTCCCACAGCATTGCAGATTCAGCAGCTTTGGCTATTCACACGCCTGTAGGTACGGTTTTTCACTCA
GGGGATTTCAAGATCGATTTTACGCCTATAGACGGGGAAGTGCCGGATTTGCACCGGTTTGCACAATTGGGAGAAAAGGG
CGTACTGGTGATGCTGTGTGACAGCACGAACATTGAAAGGCCGGGCTATACGATGTCTGAAAGAACAGTAGGGGAGACTT
TTGATAATCTTTTCAGAAAGGCTGAGCAGAGGATAATTGTAGCCACTTTTGCTTCAAATATTCACAGGGTTCAGCAGATA
ATAAATTCCGCACAGAAGTACGGAAGGAAAGTGGCCATATCAGGAAGAAGCATGGTAAATGTTGTGAATGTAGCCATGGA
GCTTGGATATCTGACAGTGCCAGAAGGGCTTTTGATAGATTTGGATGAGGCGAATAAACTTCCCCACAACAAAGTAGTGA
TAATCACCACAGGAAGTCAAGGTGAACCGATGTCGGCACTTACCAGAATGGCCTCTTCTGAACACAAAAAAGTGGAGATT
GTCCCTGGAGACACTGTCATAATCTCGGCTTCTCCAATTCCGGGAAATGAAAGATTGATCTCAAGAGTTATAAATCAGCT
TTTCAAAAAGGGTGCCAATGTGATATATGAAGCTTTAGCAGATATACACGTTTCTGGACATGCATGCCAGGAAGAGATCA
AACTTTTGCACACCCTTATAAAGCCGAAATTTTTCATACCTGTTCACGGCGAGTACAGGCACCTGGTGCAGCACGCAAAA
CTTGCTGAAAGCCTTGGAATGCCGCCGGAGAACATCTTTGTAGTGGACAACGGTACAGTGCTGGAATTTACGAAAGATTC
AGGTAGAATTGCAGGTACAGTCACAGCCGGTAAGGTATTGGTGGACGGATTGGGAGTTGGAGATGTGGGCAATATAGTCC
TGCGGGACAGAAAGCACCTTGCCCAGGATGGCCTGTTAGTTGTGGTTGTCACGATTTCCAAAGAGACTGGAGCGGTGATA
GCAGGGCCAGATATTATTTCACGCGGATTTGTGTATGTGAGAGAGTCTGAAGATTTGATGGAGGAGTCCAAGAACATCGT
ACGAGAAGTCCTTGCAAAATGTGAAAAAGAAGAAATCAACGAGTGGGCTACTATAAAATCCATGATAAAGGATAATTTAA
GCAATTTCCTCTATGAGAAAACTAAAAGGAATCCAATGATACTGCCTATTATAATGGAAATTTAA

Upstream 100 bases:

>100_bases
GAAATAAAGTATAATTTATATTAACTGGTGTAAGGTACGGGTCTATTTTTATTTAAAGGGGAGAGGGGTAAAAAAATATC
TAACGAAAGGAGAAAGGTAT

Downstream 100 bases:

>100_bases
CACAAAGAATGGAGAGAGGAAAAATGGGTAAAATTGATGTAAAATACATTGCGAAAGCGGGAGTTATTGCAGCAATTTAT
TTTGCAGTGACTTTTTTGCT

Product: metallo-beta-lactamase superfamily hydrolase

Products: NA

Alternate protein names: RNase J1 [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MAHKAKLKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLKNREKVKAIVLTHGHEDHIGA
LPYVLKQLNVPIYGTRLTIGLVEYKLKEHGLLRDSKLITVKPRETVEIGQFKVEFIRTSHSIADSAALAIHTPVGTVFHS
GDFKIDFTPIDGEVPDLHRFAQLGEKGVLVMLCDSTNIERPGYTMSERTVGETFDNLFRKAEQRIIVATFASNIHRVQQI
INSAQKYGRKVAISGRSMVNVVNVAMELGYLTVPEGLLIDLDEANKLPHNKVVIITTGSQGEPMSALTRMASSEHKKVEI
VPGDTVIISASPIPGNERLISRVINQLFKKGANVIYEALADIHVSGHACQEEIKLLHTLIKPKFFIPVHGEYRHLVQHAK
LAESLGMPPENIFVVDNGTVLEFTKDSGRIAGTVTAGKVLVDGLGVGDVGNIVLRDRKHLAQDGLLVVVVTISKETGAVI
AGPDIISRGFVYVRESEDLMEESKNIVREVLAKCEKEEINEWATIKSMIKDNLSNFLYEKTKRNPMILPIIMEI

Sequences:

>Translated_554_residues
MAHKAKLKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLKNREKVKAIVLTHGHEDHIGA
LPYVLKQLNVPIYGTRLTIGLVEYKLKEHGLLRDSKLITVKPRETVEIGQFKVEFIRTSHSIADSAALAIHTPVGTVFHS
GDFKIDFTPIDGEVPDLHRFAQLGEKGVLVMLCDSTNIERPGYTMSERTVGETFDNLFRKAEQRIIVATFASNIHRVQQI
INSAQKYGRKVAISGRSMVNVVNVAMELGYLTVPEGLLIDLDEANKLPHNKVVIITTGSQGEPMSALTRMASSEHKKVEI
VPGDTVIISASPIPGNERLISRVINQLFKKGANVIYEALADIHVSGHACQEEIKLLHTLIKPKFFIPVHGEYRHLVQHAK
LAESLGMPPENIFVVDNGTVLEFTKDSGRIAGTVTAGKVLVDGLGVGDVGNIVLRDRKHLAQDGLLVVVVTISKETGAVI
AGPDIISRGFVYVRESEDLMEESKNIVREVLAKCEKEEINEWATIKSMIKDNLSNFLYEKTKRNPMILPIIMEI
>Mature_553_residues
AHKAKLKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLKNREKVKAIVLTHGHEDHIGAL
PYVLKQLNVPIYGTRLTIGLVEYKLKEHGLLRDSKLITVKPRETVEIGQFKVEFIRTSHSIADSAALAIHTPVGTVFHSG
DFKIDFTPIDGEVPDLHRFAQLGEKGVLVMLCDSTNIERPGYTMSERTVGETFDNLFRKAEQRIIVATFASNIHRVQQII
NSAQKYGRKVAISGRSMVNVVNVAMELGYLTVPEGLLIDLDEANKLPHNKVVIITTGSQGEPMSALTRMASSEHKKVEIV
PGDTVIISASPIPGNERLISRVINQLFKKGANVIYEALADIHVSGHACQEEIKLLHTLIKPKFFIPVHGEYRHLVQHAKL
AESLGMPPENIFVVDNGTVLEFTKDSGRIAGTVTAGKVLVDGLGVGDVGNIVLRDRKHLAQDGLLVVVVTISKETGAVIA
GPDIISRGFVYVRESEDLMEESKNIVREVLAKCEKEEINEWATIKSMIKDNLSNFLYEKTKRNPMILPIIMEI

Specific function: Cleaves the 5'-leader sequence of certain mRNAs. May play a role in maturation and stability of specific mRNAs. Is also required for the maturation of the 16S rRNA. Acts preferentially on 16S rRNA precursors after association of the 30S and 50S ribosomal

COG id: COG0595

COG function: function code R; Predicted hydrolase of the metallo-beta-lactamase superfamily

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR011108
- InterPro:   IPR004613
- InterPro:   IPR001587 [H]

Pfam domain/function: PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 61214; Mature: 61083

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01292 UPF0036

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHKAKLKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLK
CCCCCEEEEEECCCHHHHCCCCEEEEECCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHC
NREKVKAIVLTHGHEDHIGALPYVLKQLNVPIYGTRLTIGLVEYKLKEHGLLRDSKLITV
CCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEEEEHHHHHHHHCCCCCCCEEEEE
KPRETVEIGQFKVEFIRTSHSIADSAALAIHTPVGTVFHSGDFKIDFTPIDGEVPDLHRF
CCCCCEECCCEEEEEEECCHHHCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCHHHHH
AQLGEKGVLVMLCDSTNIERPGYTMSERTVGETFDNLFRKAEQRIIVATFASNIHRVQQI
HHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHH
INSAQKYGRKVAISGRSMVNVVNVAMELGYLTVPEGLLIDLDEANKLPHNKVVIITTGSQ
HHHHHHCCCEEEECCCHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCCEEEEEECCC
GEPMSALTRMASSEHKKVEIVPGDTVIISASPIPGNERLISRVINQLFKKGANVIYEALA
CCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DIHVSGHACQEEIKLLHTLIKPKFFIPVHGEYRHLVQHAKLAESLGMPPENIFVVDNGTV
HHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
LEFTKDSGRIAGTVTAGKVLVDGLGVGDVGNIVLRDRKHLAQDGLLVVVVTISKETGAVI
EEEECCCCCEEEEEEECEEEEECCCCCCCCCEEECCCHHHCCCCEEEEEEEECCCCCCEE
AGPDIISRGFVYVRESEDLMEESKNIVREVLAKCEKEEINEWATIKSMIKDNLSNFLYEK
ECCHHHHCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKRNPMILPIIMEI
HCCCCEEEEEEEEC
>Mature Secondary Structure 
AHKAKLKIIPLGGLNEIGKNMTVFEYGNDIIVVDCGLAFPDDEMLGIDLVIPDITYLLK
CCCCEEEEEECCCHHHHCCCCEEEEECCEEEEEECCCCCCCCCEEEEEEEHHHHHHHHC
NREKVKAIVLTHGHEDHIGALPYVLKQLNVPIYGTRLTIGLVEYKLKEHGLLRDSKLITV
CCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEEEEHHHHHHHHCCCCCCCEEEEE
KPRETVEIGQFKVEFIRTSHSIADSAALAIHTPVGTVFHSGDFKIDFTPIDGEVPDLHRF
CCCCCEECCCEEEEEEECCHHHCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCHHHHH
AQLGEKGVLVMLCDSTNIERPGYTMSERTVGETFDNLFRKAEQRIIVATFASNIHRVQQI
HHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEHHHHHHHHHHHH
INSAQKYGRKVAISGRSMVNVVNVAMELGYLTVPEGLLIDLDEANKLPHNKVVIITTGSQ
HHHHHHCCCEEEECCCHHHHHHHHHHHCCEEECCCCEEEEECCCCCCCCCCEEEEEECCC
GEPMSALTRMASSEHKKVEIVPGDTVIISASPIPGNERLISRVINQLFKKGANVIYEALA
CCCHHHHHHHHCCCCCEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DIHVSGHACQEEIKLLHTLIKPKFFIPVHGEYRHLVQHAKLAESLGMPPENIFVVDNGTV
HHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEECCEE
LEFTKDSGRIAGTVTAGKVLVDGLGVGDVGNIVLRDRKHLAQDGLLVVVVTISKETGAVI
EEEECCCCCEEEEEEECEEEEECCCCCCCCCEEECCCHHHCCCCEEEEEEEECCCCCCEE
AGPDIISRGFVYVRESEDLMEESKNIVREVLAKCEKEEINEWATIKSMIKDNLSNFLYEK
ECCHHHHCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TKRNPMILPIIMEI
HCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]