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The map label for this gene is Fur3 [H]

Identifier: 20807701

GI number: 20807701

Start: 1252243

End: 1252680

Strand: Direct

Name: Fur3 [H]

Synonym: TTE1252

Alternate gene names: 20807701

Gene position: 1252243-1252680 (Clockwise)

Preceding gene: 20807700

Following gene: 20807702

Centisome position: 46.56

GC content: 37.67

Gene sequence:

>438_bases
GTGAATGAATTTGATAAACTTAAGGAAAAATTGAAAGAGAAGGGTTTTAAGTTGACTACGCAGCGGCGGGTAATTCTGGA
CGTGATAATGGAAAATAAAAATAAACATCTGTCTTCAGAAGAGATATACGACCTTGTTAAGCGGAAGTATCCTGAGATAG
GCTTGGCTACAGTTTACAGGACTCTACAGCTTTTTGAGGAACTGGGACTTGTATATAAATTGAATTTTGATGAGGGACGG
AACAGGTATGAGCTTTACCAGGAAGATGCTCATCAGCACCATCACCTGATATGTTTAAAGTGCGGAAATGTCATAGAAAT
GGAAGGAGATTTGCTGGAAGACTTGGAGAAGCTGATTGAGAAGACGAAGAATTTTGAAATTGTTGACCACAACGTGAAAT
TCTACGGTTATTGCAGTAATTGTAGAAATAAAGTATAA

Upstream 100 bases:

>100_bases
ACGGCGAATAATAGTTGATATTTTTTGAGAAAAACTTGTTGACAATTGAAAATGAATATCATAAACTATTTGTAGTTGAA
ATAATTTGGTGGTGAAAAAA

Downstream 100 bases:

>100_bases
TTTATATTAACTGGTGTAAGGTACGGGTCTATTTTTATTTAAAGGGGAGAGGGGTAAAAAAATATCTAACGAAAGGAGAA
AGGTATTTGGCGCACAAGGC

Product: Fe2+/Zn2+ uptake regulation proteins

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MNEFDKLKEKLKEKGFKLTTQRRVILDVIMENKNKHLSSEEIYDLVKRKYPEIGLATVYRTLQLFEELGLVYKLNFDEGR
NRYELYQEDAHQHHHLICLKCGNVIEMEGDLLEDLEKLIEKTKNFEIVDHNVKFYGYCSNCRNKV

Sequences:

>Translated_145_residues
MNEFDKLKEKLKEKGFKLTTQRRVILDVIMENKNKHLSSEEIYDLVKRKYPEIGLATVYRTLQLFEELGLVYKLNFDEGR
NRYELYQEDAHQHHHLICLKCGNVIEMEGDLLEDLEKLIEKTKNFEIVDHNVKFYGYCSNCRNKV
>Mature_145_residues
MNEFDKLKEKLKEKGFKLTTQRRVILDVIMENKNKHLSSEEIYDLVKRKYPEIGLATVYRTLQLFEELGLVYKLNFDEGR
NRYELYQEDAHQHHHLICLKCGNVIEMEGDLLEDLEKLIEKTKNFEIVDHNVKFYGYCSNCRNKV

Specific function: Iron uptake repressor. Acts on the transcription of ferri-siderophore uptake genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=134, Percent_Identity=41.044776119403, Blast_Score=105, Evalue=9e-25,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 17359; Mature: 17359

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFDKLKEKLKEKGFKLTTQRRVILDVIMENKNKHLSSEEIYDLVKRKYPEIGLATVYR
CCHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
TLQLFEELGLVYKLNFDEGRNRYELYQEDAHQHHHLICLKCGNVIEMEGDLLEDLEKLIE
HHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCEEEECCHHHHHHHHHHH
KTKNFEIVDHNVKFYGYCSNCRNKV
HCCCCEEEECCEEEEEEECCCCCCC
>Mature Secondary Structure
MNEFDKLKEKLKEKGFKLTTQRRVILDVIMENKNKHLSSEEIYDLVKRKYPEIGLATVYR
CCHHHHHHHHHHHCCCEECHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHH
TLQLFEELGLVYKLNFDEGRNRYELYQEDAHQHHHLICLKCGNVIEMEGDLLEDLEKLIE
HHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCCCEEEEECCCEEEECCHHHHHHHHHHH
KTKNFEIVDHNVKFYGYCSNCRNKV
HCCCCEEEECCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9701813 [H]