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The map label for this gene is AvtA2 [C]

Identifier: 20807661

GI number: 20807661

Start: 1206019

End: 1207206

Strand: Direct

Name: AvtA2 [C]

Synonym: TTE1206

Alternate gene names: 20807661

Gene position: 1206019-1207206 (Clockwise)

Preceding gene: 20807660

Following gene: 20807662

Centisome position: 44.84

GC content: 36.7

Gene sequence:

>1188_bases
ATGAATCTCTCGCAGAATGCTCTTCAAATAACCCCTTCTATGACTTTAGAAATAACGGCAAAGGCGAGACAGTTAAAGGC
AGAGGGAGTTGATGTCATAGACTTTGGAGTGGGTGAACCTGATTTTGATACTCCTGACTATATAAAAGAGGCTGCAATTG
AAGCGATAAAGAAAGGCTATACCAAGTATACGCCTGCTTCGGGAATACTTGAACTAAAAAAGGCTATATGTGAAAAACTG
AAAAGAGAAAATGGTCTTTTTTATGAACCAGAGCAGATTGTAGTTTCTAATGGGGCTAAACATTCTATATATAACGCACT
TTCTGCAATATTAAACCCGGGAGATGAAGTTATCATACCTGTACCTTATTGGCTAAGTTATCCTGAAATGGTAAGGCTCG
CTTATGGTAAACCAGTGTTTGTTCAAACAAAGGAAGAAAATAATTTCAAAATTACAGCTGAAGAACTCACGGCCGCCATA
AACCCGAAAACGAAAGCTCTAATATTAAACAGCCCGAACAATCCCACAGGAGCTGTTTATACAAGAAAGGAGCTACAAGA
TATTGCTGAAGTGGTAGAAGAAACAGGAATATTTGTGATTTCTGATGAGGTATATGAAAAATTGATTTATGAAGGAGAAC
ATGTCAGTATAGCTTCATTGGGTGAAAAAATTAAAGAACTTACGATAGTGGTAAATGGCATGTCCAAAGCTTATGCAATG
ACGGGATGGAGGATAGGTTATACTGCATCTTCTTTAGACGTTGCGAAAGTTATGGCTAATATTCAAAGCCATACTACTTC
AAATCCCAATTCTATTGCTCAATATGCCAGCGTCACAGCATTGACTGGAGATGGAGTGGCAATAAAAAGAATGGTAGAAG
AATTTAACAAAAGAAGGCTTTACGCTGTAGAAAGAATAAGTAAGATGAAAGGCTTAAAAGCAGTTAGACCACAAGGAGCT
TTTTACGTCTTTGTGAACATTGAAGAATATGTAGGCAAAAAAGTAAATGGTAGAAAAATAAAAGGGTCTTTAGATTTTGC
TACCCTTCTCATTGAAGAGGCAAATGTAGCTGTAGTTCCTGCCTTACCTTTTGGTATGGATAATTATATAAGAATCTCAT
ACGCAACCTCTATGGAAAACATAGAAAAAGGACTTGACAGAATTGAAAACTTCTTGAATAAGATTTAG

Upstream 100 bases:

>100_bases
GAATATAAGGTTGATATGAGAACAGCTGCTTATATGATTGCTATAAAGAGAATATATGAAGCGATGAAAGTAAGAGGATG
GATATAGAGGAGGTAGAAAA

Downstream 100 bases:

>100_bases
AACTTTTAAGTAGGAGGAGTTGATAAAGGTGAAATTTGACGGGGTAAGACCCACCCGCGTAGAAGTATATCTAGATGCAA
TAACACATAACTTCAGAGAA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MNLSQNALQITPSMTLEITAKARQLKAEGVDVIDFGVGEPDFDTPDYIKEAAIEAIKKGYTKYTPASGILELKKAICEKL
KRENGLFYEPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVQTKEENNFKITAEELTAAI
NPKTKALILNSPNNPTGAVYTRKELQDIAEVVEETGIFVISDEVYEKLIYEGEHVSIASLGEKIKELTIVVNGMSKAYAM
TGWRIGYTASSLDVAKVMANIQSHTTSNPNSIAQYASVTALTGDGVAIKRMVEEFNKRRLYAVERISKMKGLKAVRPQGA
FYVFVNIEEYVGKKVNGRKIKGSLDFATLLIEEANVAVVPALPFGMDNYIRISYATSMENIEKGLDRIENFLNKI

Sequences:

>Translated_395_residues
MNLSQNALQITPSMTLEITAKARQLKAEGVDVIDFGVGEPDFDTPDYIKEAAIEAIKKGYTKYTPASGILELKKAICEKL
KRENGLFYEPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVQTKEENNFKITAEELTAAI
NPKTKALILNSPNNPTGAVYTRKELQDIAEVVEETGIFVISDEVYEKLIYEGEHVSIASLGEKIKELTIVVNGMSKAYAM
TGWRIGYTASSLDVAKVMANIQSHTTSNPNSIAQYASVTALTGDGVAIKRMVEEFNKRRLYAVERISKMKGLKAVRPQGA
FYVFVNIEEYVGKKVNGRKIKGSLDFATLLIEEANVAVVPALPFGMDNYIRISYATSMENIEKGLDRIENFLNKI
>Mature_395_residues
MNLSQNALQITPSMTLEITAKARQLKAEGVDVIDFGVGEPDFDTPDYIKEAAIEAIKKGYTKYTPASGILELKKAICEKL
KRENGLFYEPEQIVVSNGAKHSIYNALSAILNPGDEVIIPVPYWLSYPEMVRLAYGKPVFVQTKEENNFKITAEELTAAI
NPKTKALILNSPNNPTGAVYTRKELQDIAEVVEETGIFVISDEVYEKLIYEGEHVSIASLGEKIKELTIVVNGMSKAYAM
TGWRIGYTASSLDVAKVMANIQSHTTSNPNSIAQYASVTALTGDGVAIKRMVEEFNKRRLYAVERISKMKGLKAVRPQGA
FYVFVNIEEYVGKKVNGRKIKGSLDFATLLIEEANVAVVPALPFGMDNYIRISYATSMENIEKGLDRIENFLNKI

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=378, Percent_Identity=26.7195767195767, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI169881279, Length=378, Percent_Identity=26.7195767195767, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI56713254, Length=324, Percent_Identity=32.7160493827161, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI56713256, Length=324, Percent_Identity=32.7160493827161, Blast_Score=155, Evalue=8e-38,
Organism=Homo sapiens, GI169881281, Length=375, Percent_Identity=23.7333333333333, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4507369, Length=384, Percent_Identity=23.1770833333333, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI187936925, Length=396, Percent_Identity=26.5151515151515, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI14211921, Length=396, Percent_Identity=26.5151515151515, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI215599424, Length=397, Percent_Identity=21.1586901763224, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI19263340, Length=397, Percent_Identity=21.1586901763224, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI149944424, Length=270, Percent_Identity=26.6666666666667, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=396, Percent_Identity=28.5353535353535, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786816, Length=391, Percent_Identity=25.5754475703325, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1788722, Length=386, Percent_Identity=26.4248704663212, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787909, Length=384, Percent_Identity=22.3958333333333, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787710, Length=245, Percent_Identity=24.4897959183673, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=26.9129287598945, Blast_Score=134, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=425, Percent_Identity=25.4117647058824, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI71994476, Length=425, Percent_Identity=25.4117647058824, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17567369, Length=407, Percent_Identity=25.7985257985258, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71981209, Length=368, Percent_Identity=23.6413043478261, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981215, Length=203, Percent_Identity=25.615763546798, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=395, Percent_Identity=27.5949367088608, Blast_Score=132, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6323118, Length=389, Percent_Identity=23.3933161953728, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=338, Percent_Identity=21.301775147929, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573069, Length=419, Percent_Identity=26.491646778043, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24646114, Length=419, Percent_Identity=26.491646778043, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573067, Length=419, Percent_Identity=26.491646778043, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28573065, Length=419, Percent_Identity=26.491646778043, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI18859735, Length=387, Percent_Identity=23.7726098191214, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641770, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641760, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641768, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641766, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24641764, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI45551451, Length=377, Percent_Identity=26.525198938992, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43755; Mature: 43755

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00105 AA_TRANSFER_CLASS_1 ; PS01319 RBFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSQNALQITPSMTLEITAKARQLKAEGVDVIDFGVGEPDFDTPDYIKEAAIEAIKKGY
CCCCCCCEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTPASGILELKKAICEKLKRENGLFYEPEQIVVSNGAKHSIYNALSAILNPGDEVIIP
CCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
VPYWLSYPEMVRLAYGKPVFVQTKEENNFKITAEELTAAINPKTKALILNSPNNPTGAVY
CHHHCCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCCCEE
TRKELQDIAEVVEETGIFVISDEVYEKLIYEGEHVSIASLGEKIKELTIVVNGMSKAYAM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCEEHHHHHHHHHEEEEEEECCCHHHEE
TGWRIGYTASSLDVAKVMANIQSHTTSNPNSIAQYASVTALTGDGVAIKRMVEEFNKRRL
CCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHH
YAVERISKMKGLKAVRPQGAFYVFVNIEEYVGKKVNGRKIKGSLDFATLLIEEANVAVVP
HHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCCCEEECCCCEEEEEEECCCEEEEE
ALPFGMDNYIRISYATSMENIEKGLDRIENFLNKI
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLSQNALQITPSMTLEITAKARQLKAEGVDVIDFGVGEPDFDTPDYIKEAAIEAIKKGY
CCCCCCCEEECCCEEEEEEHHHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCC
TKYTPASGILELKKAICEKLKRENGLFYEPEQIVVSNGAKHSIYNALSAILNPGDEVIIP
CCCCCCHHHHHHHHHHHHHHHHCCCCEECCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
VPYWLSYPEMVRLAYGKPVFVQTKEENNFKITAEELTAAINPKTKALILNSPNNPTGAVY
CHHHCCCHHHHHHHCCCEEEEEECCCCCEEEEHHHHHHHCCCCCEEEEEECCCCCCCCEE
TRKELQDIAEVVEETGIFVISDEVYEKLIYEGEHVSIASLGEKIKELTIVVNGMSKAYAM
EHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCCCEEHHHHHHHHHEEEEEEECCCHHHEE
TGWRIGYTASSLDVAKVMANIQSHTTSNPNSIAQYASVTALTGDGVAIKRMVEEFNKRRL
CCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHH
YAVERISKMKGLKAVRPQGAFYVFVNIEEYVGKKVNGRKIKGSLDFATLLIEEANVAVVP
HHHHHHHHHCCCCCCCCCCCEEEEEEEHHHHCCCCCCCEEECCCCEEEEEEECCCEEEEE
ALPFGMDNYIRISYATSMENIEKGLDRIENFLNKI
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1990006; 2155199 [H]