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The map label for this gene is KamA2 [H]

Identifier: 20807659

GI number: 20807659

Start: 1203424

End: 1204683

Strand: Direct

Name: KamA2 [H]

Synonym: TTE1204

Alternate gene names: 20807659

Gene position: 1203424-1204683 (Clockwise)

Preceding gene: 20807658

Following gene: 20807660

Centisome position: 44.75

GC content: 38.1

Gene sequence:

>1260_bases
ATGAGCAGCACGGGTTCACTCACAGTGGAGGAAAAAAGGAAAATAGCACTCCAAAGAGCGGAAGAGTTAAAAAAGAAGAT
AGAGCCATACTTGAGAGCATCTGAAAAAATAGAGACGGGCTTTAAGTTATCAGAAAAATTTAGAGAAAACAAGGAGAAAA
TTAAAAACTTATTTGGAGCAACAGAAGAGGAATGGAATGATTGGCGATGGCAGATAAGAAATCGTATAAGTGATGTTGAA
ACTCTCAAAAAGATTGTAAACCTTTCTGAGGAGGAAATTGAAAACATAAAGAGGGTAAGTACTCGCTACAGATGGGCAAT
TTCACCATACTATGCTTCTTTAATGGATCCGGATAATCCTTTCTGTCCTATTCGAATGAGAGCTATCCCAAGTATTAAGG
AACTTACAGATAAATATGGAGTTCCAGACCCGATGGCAGAAGAATATACTTCTCCCGCTCCTTTAATAACACGTCGTTAT
CCTGATCGACTGATTATAAACGTAACAAATCAATGTGGCATGTTCTGTAGACATTGTCAGAGGAGACGCAACATAGGAGA
AGTGGATTATCCTGCAAAACACGAAGACATAGAAGCGGCATTAGAATATATTCGAAATAATCCAGAAATTAGAGATGTGC
TGATAACAGGGGGAGACCCTCTCACTCTTGAGGATGAAAAAATCGACTGGATTTTGTCAGAATTAGATAAAATTCCACAT
GTAGAAATAAAACGAATAGGGACGGCTGCCCCAGTGACTTTTCCACAGAGAATTACCGATGAATTATGCAAGATTTTAAC
AAAACATCTGCCTCTGTACATTAATACCCAGTTTAATCATCCAAAAGAAGTTACTGAAGAAGCAAAAGAGGCTTGCTTTA
AATTAGCAAGAGCTGGGGTGGCATTAGGAAATCAAGCAGTGCTTTTAAAAGGGATAAATAATGACCCTCATGTTATGAAA
AAGTTAAACCACGAATTACTTAGAATTATGGTTAAACCTTACTACATTTTCCATGCGAAATCTGTTCAAGGGACTACCCA
TTTTGTTACTACAGTTCAAGATGGATTAGAGATTATGGAACAACTTCGCGGTTATACTTCAGGGCTTGCCATTCCGTGGT
ATATAATCAATGCACCTGAAGGGCATGGGAAGACTCCTATTGTGCCTCAGTATCTCCTTATGGTTGGGAAAGAATATGTT
CTTATAAGAAATTGGGAAGGAAAAGTTTTTGAATATCCGAATGGCTTCCCTGACGATTAA

Upstream 100 bases:

>100_bases
GTTATTAAATGTTGGAGTGTATGTAAAATTTATTTTACAAGAGAGTTCACAGAGTTCAGATATCGTTTGCAAGTTTTGTA
AAGGAAGGAGGTGCAAATTT

Downstream 100 bases:

>100_bases
ATTTTTATAGGGGTAAGGGGAAGAAATGTAACATTTTCCCTTACCCCGAAAAATAAAAAATTATGAGGAGGAATGTAAGA
ATGGCAGTTAATCCTTTAAA

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSSTGSLTVEEKRKIALQRAEELKKKIEPYLRASEKIETGFKLSEKFRENKEKIKNLFGATEEEWNDWRWQIRNRISDVE
TLKKIVNLSEEEIENIKRVSTRYRWAISPYYASLMDPDNPFCPIRMRAIPSIKELTDKYGVPDPMAEEYTSPAPLITRRY
PDRLIINVTNQCGMFCRHCQRRRNIGEVDYPAKHEDIEAALEYIRNNPEIRDVLITGGDPLTLEDEKIDWILSELDKIPH
VEIKRIGTAAPVTFPQRITDELCKILTKHLPLYINTQFNHPKEVTEEAKEACFKLARAGVALGNQAVLLKGINNDPHVMK
KLNHELLRIMVKPYYIFHAKSVQGTTHFVTTVQDGLEIMEQLRGYTSGLAIPWYIINAPEGHGKTPIVPQYLLMVGKEYV
LIRNWEGKVFEYPNGFPDD

Sequences:

>Translated_419_residues
MSSTGSLTVEEKRKIALQRAEELKKKIEPYLRASEKIETGFKLSEKFRENKEKIKNLFGATEEEWNDWRWQIRNRISDVE
TLKKIVNLSEEEIENIKRVSTRYRWAISPYYASLMDPDNPFCPIRMRAIPSIKELTDKYGVPDPMAEEYTSPAPLITRRY
PDRLIINVTNQCGMFCRHCQRRRNIGEVDYPAKHEDIEAALEYIRNNPEIRDVLITGGDPLTLEDEKIDWILSELDKIPH
VEIKRIGTAAPVTFPQRITDELCKILTKHLPLYINTQFNHPKEVTEEAKEACFKLARAGVALGNQAVLLKGINNDPHVMK
KLNHELLRIMVKPYYIFHAKSVQGTTHFVTTVQDGLEIMEQLRGYTSGLAIPWYIINAPEGHGKTPIVPQYLLMVGKEYV
LIRNWEGKVFEYPNGFPDD
>Mature_418_residues
SSTGSLTVEEKRKIALQRAEELKKKIEPYLRASEKIETGFKLSEKFRENKEKIKNLFGATEEEWNDWRWQIRNRISDVET
LKKIVNLSEEEIENIKRVSTRYRWAISPYYASLMDPDNPFCPIRMRAIPSIKELTDKYGVPDPMAEEYTSPAPLITRRYP
DRLIINVTNQCGMFCRHCQRRRNIGEVDYPAKHEDIEAALEYIRNNPEIRDVLITGGDPLTLEDEKIDWILSELDKIPHV
EIKRIGTAAPVTFPQRITDELCKILTKHLPLYINTQFNHPKEVTEEAKEACFKLARAGVALGNQAVLLKGINNDPHVMKK
LNHELLRIMVKPYYIFHAKSVQGTTHFVTTVQDGLEIMEQLRGYTSGLAIPWYIINAPEGHGKTPIVPQYLLMVGKEYVL
IRNWEGKVFEYPNGFPDD

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=308, Percent_Identity=29.5454545454545, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR006638
- InterPro:   IPR022459 [H]

Pfam domain/function: NA

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 48524; Mature: 48393

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTGSLTVEEKRKIALQRAEELKKKIEPYLRASEKIETGFKLSEKFRENKEKIKNLFGA
CCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
TEEEWNDWRWQIRNRISDVETLKKIVNLSEEEIENIKRVSTRYRWAISPYYASLMDPDNP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECHHHHHHCCCCCC
FCPIRMRAIPSIKELTDKYGVPDPMAEEYTSPAPLITRRYPDRLIINVTNQCGMFCRHCQ
CCCEEHHCCCCHHHHHHHCCCCCCCHHHCCCCCCCHHHCCCCEEEEEECHHHHHHHHHHH
RRRNIGEVDYPAKHEDIEAALEYIRNNPEIRDVLITGGDPLTLEDEKIDWILSELDKIPH
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEECHHHHHHHHHHHHCCCC
VEIKRIGTAAPVTFPQRITDELCKILTKHLPLYINTQFNHPKEVTEEAKEACFKLARAGV
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ALGNQAVLLKGINNDPHVMKKLNHELLRIMVKPYYIFHAKSVQGTTHFVTTVQDGLEIME
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QLRGYTSGLAIPWYIINAPEGHGKTPIVPQYLLMVGKEYVLIRNWEGKVFEYPNGFPDD
HHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
SSTGSLTVEEKRKIALQRAEELKKKIEPYLRASEKIETGFKLSEKFRENKEKIKNLFGA
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
TEEEWNDWRWQIRNRISDVETLKKIVNLSEEEIENIKRVSTRYRWAISPYYASLMDPDNP
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEECHHHHHHCCCCCC
FCPIRMRAIPSIKELTDKYGVPDPMAEEYTSPAPLITRRYPDRLIINVTNQCGMFCRHCQ
CCCEEHHCCCCHHHHHHHCCCCCCCHHHCCCCCCCHHHCCCCEEEEEECHHHHHHHHHHH
RRRNIGEVDYPAKHEDIEAALEYIRNNPEIRDVLITGGDPLTLEDEKIDWILSELDKIPH
HHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEECHHHHHHHHHHHHCCCC
VEIKRIGTAAPVTFPQRITDELCKILTKHLPLYINTQFNHPKEVTEEAKEACFKLARAGV
CCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
ALGNQAVLLKGINNDPHVMKKLNHELLRIMVKPYYIFHAKSVQGTTHFVTTVQDGLEIME
HCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHH
QLRGYTSGLAIPWYIINAPEGHGKTPIVPQYLLMVGKEYVLIRNWEGKVFEYPNGFPDD
HHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9734814; 9384377; 10839984 [H]