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The map label for this gene is secD [H]

Identifier: 20807644

GI number: 20807644

Start: 1184732

End: 1185964

Strand: Direct

Name: secD [H]

Synonym: TTE1188

Alternate gene names: 20807644

Gene position: 1184732-1185964 (Clockwise)

Preceding gene: 20807643

Following gene: 20807645

Centisome position: 44.05

GC content: 41.77

Gene sequence:

>1233_bases
ATGAGAAGTCGAGGCTTTATTAAATTTTTTTCTGTAATTTTGGTCTCAGCTTTAGTAGCGTATGTGGCTTTCTTTGGGAT
CAAAGCAGGGAATTTTTCTATTTCTCCAATTCAAGACCACATAAGGTTGGGACTTGATTTAAGAGGTGGAGTGTACGTAC
TGGAAGAAGCGCAGGGCAATGTCACACAGGATGCCATAAACAAGGCTATTGCGGTAATAAGAAATAGAGTAGACGCTTTG
GGTGTGACTCAGCCTGTCATTGCTCAACAAGGTTCCAACAGAATTCGCGTGGAGCTTCCAGGTATGAAAGATCCGGACAA
GGCTATAGAGATTATAGGTAAAACGGCGCAACTTAAATTTGTGGGTCCTGACGGAAAGGTCATCTTGACAGGGGCGAATG
TAAAAGATTCAAAGGCAGTTTACGCCCAAACCTCAACTGGACAGCAGCCACAAGTCACTCTTGTTTTGGATGCGGAAGGA
ACGAAAAAATTTGCTGAGGCAACTCAAAAATTTTTAGGGCAGCCTATTGCTATCTTATTAGACGACAAAGTAATTTCTGC
TCCAGTGGTAAGGGATGTTATAACTACTGGAAATGCGGTGATTACTGGTCTTAAGGACTTCCAAGAAGCCTCTGAACTGG
CTACTTTGATTAGGGCAGGGTCTTTGCCTGTCACTTTAAAGCCTATAGCCTATAGTTCTGTCGGTGCGACTCTTGGACCT
AGTGCTTTAAAAGCTAGTGTAGAGGCAGGTATATATGGAACATTATTAGTAATGCTTTTTATGATGGCTTTTTACAGGTT
GCCCGGTTTCATAGCCGATTTGGCTCTTCTCATATATATACTCATAAACTTTATAATATACGCTATCTTCAATGTAACAT
TGGACCTTCCAGGAATTGCTGGATTCTTGCTTTCAATAGGTATGGCTGTTGATACCAACATCTTAATTTTTGAAAGGTTC
AAAGAAGAGCTGTGGGCAGGGAAGACCATAAGGCCTGCACTGGATGCAGGATTTGCAAAGGCTATGAGAGCAGTAATTGA
TGCGAATGTCACCACTATAATCGGCGCGATCATCCTCTTTTACTTGGGTTCAGGAAACGTAAAAGGTTTTGCTCTGACTC
TTTTAATAGGTGTGTCTTCCAGCTTATTTACTGCTATAACTGTGACAAGATTCTTACTGCACGCGCTCCTTGAGATGGAC
CTTACAAGAAATGTCAAATTCTATGGAGCATAG

Upstream 100 bases:

>100_bases
AATTAGCAAAATTGCATTTTTCTGAGTTTGGGCAATTGACCGTTTACAATAAAAGTAATATAATAGAAAATAGTTAGTCA
AACGACAAAGGAGGATTTAG

Downstream 100 bases:

>100_bases
GAGGGAATTAGATTGAATGGTCACAGATTTCACATAGATGTCATTGGCAAGACAAAAATTTGGTTTACCATTTCGGGTAT
AATGATACTGATCGGCATAA

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRSRGFIKFFSVILVSALVAYVAFFGIKAGNFSISPIQDHIRLGLDLRGGVYVLEEAQGNVTQDAINKAIAVIRNRVDAL
GVTQPVIAQQGSNRIRVELPGMKDPDKAIEIIGKTAQLKFVGPDGKVILTGANVKDSKAVYAQTSTGQQPQVTLVLDAEG
TKKFAEATQKFLGQPIAILLDDKVISAPVVRDVITTGNAVITGLKDFQEASELATLIRAGSLPVTLKPIAYSSVGATLGP
SALKASVEAGIYGTLLVMLFMMAFYRLPGFIADLALLIYILINFIIYAIFNVTLDLPGIAGFLLSIGMAVDTNILIFERF
KEELWAGKTIRPALDAGFAKAMRAVIDANVTTIIGAIILFYLGSGNVKGFALTLLIGVSSSLFTAITVTRFLLHALLEMD
LTRNVKFYGA

Sequences:

>Translated_410_residues
MRSRGFIKFFSVILVSALVAYVAFFGIKAGNFSISPIQDHIRLGLDLRGGVYVLEEAQGNVTQDAINKAIAVIRNRVDAL
GVTQPVIAQQGSNRIRVELPGMKDPDKAIEIIGKTAQLKFVGPDGKVILTGANVKDSKAVYAQTSTGQQPQVTLVLDAEG
TKKFAEATQKFLGQPIAILLDDKVISAPVVRDVITTGNAVITGLKDFQEASELATLIRAGSLPVTLKPIAYSSVGATLGP
SALKASVEAGIYGTLLVMLFMMAFYRLPGFIADLALLIYILINFIIYAIFNVTLDLPGIAGFLLSIGMAVDTNILIFERF
KEELWAGKTIRPALDAGFAKAMRAVIDANVTTIIGAIILFYLGSGNVKGFALTLLIGVSSSLFTAITVTRFLLHALLEMD
LTRNVKFYGA
>Mature_410_residues
MRSRGFIKFFSVILVSALVAYVAFFGIKAGNFSISPIQDHIRLGLDLRGGVYVLEEAQGNVTQDAINKAIAVIRNRVDAL
GVTQPVIAQQGSNRIRVELPGMKDPDKAIEIIGKTAQLKFVGPDGKVILTGANVKDSKAVYAQTSTGQQPQVTLVLDAEG
TKKFAEATQKFLGQPIAILLDDKVISAPVVRDVITTGNAVITGLKDFQEASELATLIRAGSLPVTLKPIAYSSVGATLGP
SALKASVEAGIYGTLLVMLFMMAFYRLPGFIADLALLIYILINFIIYAIFNVTLDLPGIAGFLLSIGMAVDTNILIFERF
KEELWAGKTIRPALDAGFAKAMRAVIDANVTTIIGAIILFYLGSGNVKGFALTLLIGVSSSLFTAITVTRFLLHALLEMD
LTRNVKFYGA

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=384, Percent_Identity=36.4583333333333, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 43932; Mature: 43932

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSRGFIKFFSVILVSALVAYVAFFGIKAGNFSISPIQDHIRLGLDLRGGVYVLEEAQGN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEECCCEEEEECCCCC
VTQDAINKAIAVIRNRVDALGVTQPVIAQQGSNRIRVELPGMKDPDKAIEIIGKTAQLKF
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEE
VGPDGKVILTGANVKDSKAVYAQTSTGQQPQVTLVLDAEGTKKFAEATQKFLGQPIAILL
ECCCCCEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
DDKVISAPVVRDVITTGNAVITGLKDFQEASELATLIRAGSLPVTLKPIAYSSVGATLGP
CCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCCCCCH
SALKASVEAGIYGTLLVMLFMMAFYRLPGFIADLALLIYILINFIIYAIFNVTLDLPGIA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GFLLSIGMAVDTNILIFERFKEELWAGKTIRPALDAGFAKAMRAVIDANVTTIIGAIILF
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YLGSGNVKGFALTLLIGVSSSLFTAITVTRFLLHALLEMDLTRNVKFYGA
HHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MRSRGFIKFFSVILVSALVAYVAFFGIKAGNFSISPIQDHIRLGLDLRGGVYVLEEAQGN
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCEEECCCEEEEECCCCC
VTQDAINKAIAVIRNRVDALGVTQPVIAQQGSNRIRVELPGMKDPDKAIEIIGKTAQLKF
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCEEEEE
VGPDGKVILTGANVKDSKAVYAQTSTGQQPQVTLVLDAEGTKKFAEATQKFLGQPIAILL
ECCCCCEEEECCCCCCCCEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEE
DDKVISAPVVRDVITTGNAVITGLKDFQEASELATLIRAGSLPVTLKPIAYSSVGATLGP
CCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHCCCCCEEECCCEECCCCCCCCH
SALKASVEAGIYGTLLVMLFMMAFYRLPGFIADLALLIYILINFIIYAIFNVTLDLPGIA
HHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
GFLLSIGMAVDTNILIFERFKEELWAGKTIRPALDAGFAKAMRAVIDANVTTIIGAIILF
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
YLGSGNVKGFALTLLIGVSSSLFTAITVTRFLLHALLEMDLTRNVKFYGA
HHCCCCCCCEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]