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The map label for this gene is SdaA2 [H]

Identifier: 20807489

GI number: 20807489

Start: 1010627

End: 1011520

Strand: Direct

Name: SdaA2 [H]

Synonym: TTE1009

Alternate gene names: 20807489

Gene position: 1010627-1011520 (Clockwise)

Preceding gene: 20807488

Following gene: 20807490

Centisome position: 37.58

GC content: 42.39

Gene sequence:

>894_bases
ATGTATCAATTCAATTACGGATATGAACTTTTAGAGCTTACAAAAAAGTTCAATAAGCCTATATCGGAAATTGTAATGCT
GGCCGAACAGGAAAGAACAGGAGAGGACTTAGAAGTTATTTTTGAAAAAATGAAGAAAAATCTTCAGGTGATGAGAGAAG
CTATAAATAAAGGGTTAAATGAGGATATAAAGTCTGTGAGCGGTTTATCAGGAGGAGATGCCAAAAAGCTTTATGCGAGG
ATTGTGATTGGAAATACTTTGTCCTGTGAAACAATGGCAAAAGCTGCAGCTTCTGCTCTTGCCGTAACAGAGGTAAATGC
CTCAATGGGGAGGATCGTGGCTGCTCCTACAGCAGGCTCAAGTGGTGTGATACCAGGTGCTTTAATTACTGTTGCAAGGA
AATTTGGCAAGAGTGAAGATGACATGACAAAAGCGCTTTTTACAGCTTCAGGAATAGGAATTATAATAGCAAAAAATGCT
ACTTTAGCGGGAGCCGAAGGAGGGTGTCAAGCAGAAGTAGGGTCTGCCTCGGCTATGGCAGCAGGGGCTTTAGTGGAACT
CATGGGGGGAACCCCTGAGCAATGCTTGACAGCTGCTTCTTTTGCCATAATGAACTTATTGGGACTGGTATGCGATCCGG
TTGCCGGATTAGTAGAAATTCCCTGTGAGAAGAGAAATGCCTTAGGAGCTCTCAATGCAATGATATGTGCTGATTTTGCT
ATAGCGGGAATGGACAGTGTAATACCTTTTGACGAGGTTGTAGAAACTATGTACAGGGTAGGAAAGGCTATCCCAAGTGC
CTTAAGAGAAACAGCAGAAGGGGGGCTTGCCAAAACTCCAACAGCAATGAGACTTAAAAAAGAAATATTTGAAAAAGAAA
AGCGGGGGGATTAA

Upstream 100 bases:

>100_bases
GACCAGGAAATCCCTGAAAGAGCTAAAGAAGTGATTAAAAATATTGATGGAATTTTGAATGCCATAATTTTAAATCCTGT
GTAATGGAGGGCATGCTTTT

Downstream 100 bases:

>100_bases
ACATGGGAAATTTAAGAGAGAGAAGTGAAATAGATGAAAGATATAAATGGAGGTTGGAAGACATATATGAAAATGAAGAG
TTGTGGGAAGAAGACTACAG

Product: L-serine deaminase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MYQFNYGYELLELTKKFNKPISEIVMLAEQERTGEDLEVIFEKMKKNLQVMREAINKGLNEDIKSVSGLSGGDAKKLYAR
IVIGNTLSCETMAKAAASALAVTEVNASMGRIVAAPTAGSSGVIPGALITVARKFGKSEDDMTKALFTASGIGIIIAKNA
TLAGAEGGCQAEVGSASAMAAGALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVETMYRVGKAIPSALRETAEGGLAKTPTAMRLKKEIFEKEKRGD

Sequences:

>Translated_297_residues
MYQFNYGYELLELTKKFNKPISEIVMLAEQERTGEDLEVIFEKMKKNLQVMREAINKGLNEDIKSVSGLSGGDAKKLYAR
IVIGNTLSCETMAKAAASALAVTEVNASMGRIVAAPTAGSSGVIPGALITVARKFGKSEDDMTKALFTASGIGIIIAKNA
TLAGAEGGCQAEVGSASAMAAGALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVETMYRVGKAIPSALRETAEGGLAKTPTAMRLKKEIFEKEKRGD
>Mature_297_residues
MYQFNYGYELLELTKKFNKPISEIVMLAEQERTGEDLEVIFEKMKKNLQVMREAINKGLNEDIKSVSGLSGGDAKKLYAR
IVIGNTLSCETMAKAAASALAVTEVNASMGRIVAAPTAGSSGVIPGALITVARKFGKSEDDMTKALFTASGIGIIIAKNA
TLAGAEGGCQAEVGSASAMAAGALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
IAGMDSVIPFDEVVETMYRVGKAIPSALRETAEGGLAKTPTAMRLKKEIFEKEKRGD

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=289, Percent_Identity=37.0242214532872, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1788116, Length=287, Percent_Identity=36.2369337979094, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1789161, Length=182, Percent_Identity=45.6043956043956, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 31198; Mature: 31198

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYQFNYGYELLELTKKFNKPISEIVMLAEQERTGEDLEVIFEKMKKNLQVMREAINKGLN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
EDIKSVSGLSGGDAKKLYARIVIGNTLSCETMAKAAASALAVTEVNASMGRIVAAPTAGS
HHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SGVIPGALITVARKFGKSEDDMTKALFTASGIGIIIAKNATLAGAEGGCQAEVGSASAMA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCHHHHH
AGALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGMDSVIPFDEVVETMYRVGKAIPSALRETAEGGLAKTPTAMRLKKEIFEKEKRGD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MYQFNYGYELLELTKKFNKPISEIVMLAEQERTGEDLEVIFEKMKKNLQVMREAINKGLN
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
EDIKSVSGLSGGDAKKLYARIVIGNTLSCETMAKAAASALAVTEVNASMGRIVAAPTAGS
HHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
SGVIPGALITVARKFGKSEDDMTKALFTASGIGIIIAKNATLAGAEGGCQAEVGSASAMA
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCHHHHH
AGALVELMGGTPEQCLTAASFAIMNLLGLVCDPVAGLVEIPCEKRNALGALNAMICADFA
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
IAGMDSVIPFDEVVETMYRVGKAIPSALRETAEGGLAKTPTAMRLKKEIFEKEKRGD
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]