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The map label for this gene is Wzb [H]

Identifier: 20807481

GI number: 20807481

Start: 1004519

End: 1004953

Strand: Reverse

Name: Wzb [H]

Synonym: TTE1001

Alternate gene names: 20807481

Gene position: 1004953-1004519 (Counterclockwise)

Preceding gene: 20807499

Following gene: 20807479

Centisome position: 37.37

GC content: 39.08

Gene sequence:

>435_bases
ATGGCAAAGAAGATTTTGTACTTTATATGCACTGGAAATTCCTGTAGAAGTCAGATGGCAGAAGGATTTGGCAAATTTTA
CGGTGGAGATGATTTTGAAGTATATAGTGGCGGTGTAGAAGCTCACGGATTAAACTCTAAAGCCGTCGAAGTCATGAAAG
AAATAGGTATCGACATAAGCAACCAAACTTCAGACTTAATAGACGAAAATATCCTCTTTAAAGCAGATTATGTTATAACG
CTGTGCGGAGATGCTAGAGACAAATGTCCTGCTCTGCCTCCTTCTGTAAAAAGCCTCCACTGGGAATTAGAAGACCCTGC
AAGAGCGGAAGGCACAGAAGAAGAGATAATGAACAAGTTTAGAGAAGTAAGGGACATAATAAAAGAAAAAGTCAAAGCCT
TAATAGAGGAGATAAGAGAAAAATCCCTGGCATAA

Upstream 100 bases:

>100_bases
CAAAACGCTTTAACATATTCTTAACAAAAAAATACATTGTTTTTCGATTGACAAGCTTTTATAATATAGCTAAGCAGGAA
TATGAGGAGGAGGAGTTACG

Downstream 100 bases:

>100_bases
AAAGCCAGGGATTTTTTACATAATTCCTGCTTCTTTGTGCCTTTTTACAATTTCCTCAGCAAGTGCATCAAGAGCTTTAA
AGTCTTCTTCTTTTGGATAG

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MAKKILYFICTGNSCRSQMAEGFGKFYGGDDFEVYSGGVEAHGLNSKAVEVMKEIGIDISNQTSDLIDENILFKADYVIT
LCGDARDKCPALPPSVKSLHWELEDPARAEGTEEEIMNKFREVRDIIKEKVKALIEEIREKSLA

Sequences:

>Translated_144_residues
MAKKILYFICTGNSCRSQMAEGFGKFYGGDDFEVYSGGVEAHGLNSKAVEVMKEIGIDISNQTSDLIDENILFKADYVIT
LCGDARDKCPALPPSVKSLHWELEDPARAEGTEEEIMNKFREVRDIIKEKVKALIEEIREKSLA
>Mature_143_residues
AKKILYFICTGNSCRSQMAEGFGKFYGGDDFEVYSGGVEAHGLNSKAVEVMKEIGIDISNQTSDLIDENILFKADYVITL
CGDARDKCPALPPSVKSLHWELEDPARAEGTEEEIMNKFREVRDIIKEKVKALIEEIREKSLA

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16110; Mature: 15978

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKILYFICTGNSCRSQMAEGFGKFYGGDDFEVYSGGVEAHGLNSKAVEVMKEIGIDIS
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCC
NQTSDLIDENILFKADYVITLCGDARDKCPALPPSVKSLHWELEDPARAEGTEEEIMNKF
CCHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCCHHHHEECCCCCCCCCCCHHHHHHHH
REVRDIIKEKVKALIEEIREKSLA
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKKILYFICTGNSCRSQMAEGFGKFYGGDDFEVYSGGVEAHGLNSKAVEVMKEIGIDIS
CCCEEEEEECCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCC
NQTSDLIDENILFKADYVITLCGDARDKCPALPPSVKSLHWELEDPARAEGTEEEIMNKF
CCHHHHHHCCCEEECCEEEEECCCCCCCCCCCCCCHHHHEECCCCCCCCCCCHHHHHHHH
REVRDIIKEKVKALIEEIREKSLA
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA