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The map label for this gene is MhpC3 [C]

Identifier: 20807469

GI number: 20807469

Start: 993574

End: 994164

Strand: Direct

Name: MhpC3 [C]

Synonym: TTE0989

Alternate gene names: 20807469

Gene position: 993574-994164 (Clockwise)

Preceding gene: 20807468

Following gene: 20807470

Centisome position: 36.94

GC content: 34.69

Gene sequence:

>591_bases
GTGTTGATAAAAGGAGAATATGTTGATATAAAAGGCAGTAAGATTCATTATTTAGAATTAGGAAGAGATGACACACAAGA
CCTTGTAATGCTACTCCACGGCAAAAGATATACTGCTTACGATTGGGTGAATTCAGGAATAGCTGAGAATTTGGCTAATA
AAGGATTTAAAGTCATATGCTTAGAATTGCCCGGGTATGGGGCTTCAGAAGAGAGCGAACTTGAAAAAGAAGAAGTGCTG
TTTGAATTCGCAAGTAAATTAAATTTAGCCCCCTTTCATTTGGTAGGTCCTTCTTTTAGTGGTGAAATATCATTGCGATT
TGCACTCAAACACAGTAATATGCTGAAAAGTCTGACGGTAGTAGATAGTATAAACGTGGACCTCTACAAGGAGAGATTAA
AAGACATAAAAGTAAAAACTTTGATTGTGTGGGGAAAGCAAGATAATATTGCTCCTTATGAGTTTGCAGAGATGTTAAAA
GAAAATATTCCTGGAAGTTCTCTATATGTATTTGAAGATTCAGGTCATACTTGTTATTTTGACAATGCAAAGAAATTTTC
TAAGGTGTTGGGAGATTTTTTTAGAGAATAA

Upstream 100 bases:

>100_bases
GAGAATTTATTTCATTGGGGATTGTAAAGAAGTAGCATCTGCGGTAGAGGCTATAAGGGAAGGGGCAGAAGTTTCACTTT
TTATATGAGAGGTGAGACTA

Downstream 100 bases:

>100_bases
AGGGATACCGTTAAAGGTATCTCTTTTTTTATAGTTGACAAATGCGAAAAATACTGTATAATGTATACAGAACATCCCAC
AACAGTAGGGGAGTATTTTG

Product: alpha/beta superfamily hydrolase/acyltransferase

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: Abhydrolase; Alpha/Beta Hydrolase Fold Protein; Alpha/Beta Fold Family Hydrolase; Carboxylesterase; 2-Hydroxy-6-Oxo-6-Phenylhexa-2 4-Dienoate Hydrolase; Alpha/Beta Hydrolase Fold; Hydrolase Or Acyltransferase; Alpha/Beta Superfamily Hydrolase/Acyltransferase

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MLIKGEYVDIKGSKIHYLELGRDDTQDLVMLLHGKRYTAYDWVNSGIAENLANKGFKVICLELPGYGASEESELEKEEVL
FEFASKLNLAPFHLVGPSFSGEISLRFALKHSNMLKSLTVVDSINVDLYKERLKDIKVKTLIVWGKQDNIAPYEFAEMLK
ENIPGSSLYVFEDSGHTCYFDNAKKFSKVLGDFFRE

Sequences:

>Translated_196_residues
MLIKGEYVDIKGSKIHYLELGRDDTQDLVMLLHGKRYTAYDWVNSGIAENLANKGFKVICLELPGYGASEESELEKEEVL
FEFASKLNLAPFHLVGPSFSGEISLRFALKHSNMLKSLTVVDSINVDLYKERLKDIKVKTLIVWGKQDNIAPYEFAEMLK
ENIPGSSLYVFEDSGHTCYFDNAKKFSKVLGDFFRE
>Mature_196_residues
MLIKGEYVDIKGSKIHYLELGRDDTQDLVMLLHGKRYTAYDWVNSGIAENLANKGFKVICLELPGYGASEESELEKEEVL
FEFASKLNLAPFHLVGPSFSGEISLRFALKHSNMLKSLTVVDSINVDLYKERLKDIKVKTLIVWGKQDNIAPYEFAEMLK
ENIPGSSLYVFEDSGHTCYFDNAKKFSKVLGDFFRE

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI226443152, Length=198, Percent_Identity=29.2929292929293, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI14249382, Length=198, Percent_Identity=29.2929292929293, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI226437571, Length=172, Percent_Identity=30.2325581395349, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17543658, Length=178, Percent_Identity=25.8426966292135, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.7.1.- [C]

Molecular weight: Translated: 22303; Mature: 22303

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKGEYVDIKGSKIHYLELGRDDTQDLVMLLHGKRYTAYDWVNSGIAENLANKGFKVIC
CEECCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEE
LELPGYGASEESELEKEEVLFEFASKLNLAPFHLVGPSFSGEISLRFALKHSNMLKSLTV
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHH
VDSINVDLYKERLKDIKVKTLIVWGKQDNIAPYEFAEMLKENIPGSSLYVFEDSGHTCYF
HHCCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEE
DNAKKFSKVLGDFFRE
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLIKGEYVDIKGSKIHYLELGRDDTQDLVMLLHGKRYTAYDWVNSGIAENLANKGFKVIC
CEECCEEEEECCCEEEEEECCCCCHHHHHHHHCCCCCEEHHHHHHHHHHHHHCCCEEEEE
LELPGYGASEESELEKEEVLFEFASKLNLAPFHLVGPSFSGEISLRFALKHSNMLKSLTV
EECCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEEECCCCHHHHHHH
VDSINVDLYKERLKDIKVKTLIVWGKQDNIAPYEFAEMLKENIPGSSLYVFEDSGHTCYF
HHCCCHHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCEEEE
DNAKKFSKVLGDFFRE
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA