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The map label for this gene is Hit [C]

Identifier: 20807444

GI number: 20807444

Start: 968364

End: 968708

Strand: Direct

Name: Hit [C]

Synonym: TTE0963

Alternate gene names: 20807444

Gene position: 968364-968708 (Clockwise)

Preceding gene: 20807443

Following gene: 161760533

Centisome position: 36.01

GC content: 38.84

Gene sequence:

>345_bases
GTGTCGGAATGCATTTTCTGCAAAATAGTAAACAAAGAAGTTCCTTCTAATATAGTGTATGAGGATGATTTAGTTGTAGC
TTTCCGCGATATAAATCCCCAAGCTCCTGTACATATTCTAATCGTGCCAAAAGAACATATACCAACCCTTTTAGATGTTA
CTGAGGAGAACAAGCACCTGATATCTCGTGCTTACATGGTAGCAAAGGAAATAGCAAAAAAAGAGGGTATTGACGAAAAA
GGCTATAGAATTGTGACAAATTGTGGTAAAGATGGCGGACAGACAGTCTATCACCTTCATTTTCACCTTTTAGGTGGAAG
GTTTATGACTTGGCCTCCAGGGTAA

Upstream 100 bases:

>100_bases
TTGCCTGTTAGAGTAAAGGAAATAAAAAATGATTTATTGATAGGAGAAATTGAAGGAATTTATTAAGATGTGTAGAATAT
AAAAAGAGGAGGTGAAAAAG

Downstream 100 bases:

>100_bases
AATTATTGACACTTCGTGGATTTAGGAGTATAATAAAGTGAGAATTTTCAAGCTCTTAGTCACAGCAACAATTGCAGCTT
GCCTCGAGCAGTTTATTTGG

Product: diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase

Products: NA

Alternate protein names: ORF 1 [H]

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MSECIFCKIVNKEVPSNIVYEDDLVVAFRDINPQAPVHILIVPKEHIPTLLDVTEENKHLISRAYMVAKEIAKKEGIDEK
GYRIVTNCGKDGGQTVYHLHFHLLGGRFMTWPPG

Sequences:

>Translated_114_residues
MSECIFCKIVNKEVPSNIVYEDDLVVAFRDINPQAPVHILIVPKEHIPTLLDVTEENKHLISRAYMVAKEIAKKEGIDEK
GYRIVTNCGKDGGQTVYHLHFHLLGGRFMTWPPG
>Mature_113_residues
SECIFCKIVNKEVPSNIVYEDDLVVAFRDINPQAPVHILIVPKEHIPTLLDVTEENKHLISRAYMVAKEIAKKEGIDEKG
YRIVTNCGKDGGQTVYHLHFHLLGGRFMTWPPG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=113, Percent_Identity=49.5575221238938, Blast_Score=128, Evalue=8e-31,
Organism=Homo sapiens, GI4885413, Length=113, Percent_Identity=48.6725663716814, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1787346, Length=105, Percent_Identity=58.0952380952381, Blast_Score=121, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17506713, Length=113, Percent_Identity=46.0176991150442, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320078, Length=117, Percent_Identity=38.4615384615385, Blast_Score=77, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28574010, Length=112, Percent_Identity=46.4285714285714, Blast_Score=115, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24581222, Length=112, Percent_Identity=46.4285714285714, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12928; Mature: 12797

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSECIFCKIVNKEVPSNIVYEDDLVVAFRDINPQAPVHILIVPKEHIPTLLDVTEENKHL
CCCEEEEEEECCCCCCCEEECCCEEEEEECCCCCCCEEEEEECHHHCCCEEECCCCHHHH
ISRAYMVAKEIAKKEGIDEKGYRIVTNCGKDGGQTVYHLHFHLLGGRFMTWPPG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCEEEECCCC
>Mature Secondary Structure 
SECIFCKIVNKEVPSNIVYEDDLVVAFRDINPQAPVHILIVPKEHIPTLLDVTEENKHL
CCEEEEEEECCCCCCCEEECCCEEEEEECCCCCCCEEEEEECHHHCCCEEECCCCHHHH
ISRAYMVAKEIAKKEGIDEKGYRIVTNCGKDGGQTVYHLHFHLLGGRFMTWPPG
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2108129; 1472710 [H]