Click here to switch to the map view.

The map label for this gene is HolA [H]

Identifier: 20807423

GI number: 20807423

Start: 944719

End: 945735

Strand: Direct

Name: HolA [H]

Synonym: TTE0942

Alternate gene names: 20807423

Gene position: 944719-945735 (Clockwise)

Preceding gene: 20807422

Following gene: 20807425

Centisome position: 35.13

GC content: 37.46

Gene sequence:

>1017_bases
ATGAACTATAGGGAATTTGTAGAAAGCATAAAAAAGGGACAGATAGCTCCTTTATACCTTTTTTACGGAGAAGAGAGATT
TTTGCTTTTAGATGCTGTTAAGAGGTTGAAGGCAAGGCTCTTGGTGCCAGAGTTTGAGGATATGAATTACATTGTAATTG
AGAGGGAAAATCCGGAGGAATACGTAGAAGCCATCATTGAGAATTGCGAGACTCTCCCTTTTTTTTCAAATTATAAAATT
GTAGTGGTGAAAAATGAAGAAGAACAGCTTTCCAAGATAGGTGATAAAGAGTTAAAAAGGCTTACTGATTATTTTAAAAA
CAGGGTGCTAGGAAATACTAGTCTTGTTGTTGTAGTTGTAAGTGGTGAAAAAATAGATTCGAGAAAAAAATTGTACAAGT
TTATGGAAAAAGAAGCTGCTGTGGTGGAGTTTAAAAAGCTCACTCCGGAAGAGGCAGTTAATTATGCCGGCTATTTCTTA
AAAAAACACGGTAAAAAGGCTGCAAAAAAGGATGTAGAATCTCTTGTGAAAAACATAGGAACTGACCTTTACTCAATTGT
GAACGAGCTGGAGAAAGTGATAGCCTATTCAGAAGGGGAAACGCTTGATTTGGAGGAAGCAAGAGAGGTGCTTTCAGTTA
CTCTCCAGCAGAACGTGTTTCACCTTGTGAATGCAATAGGGATGAAAAAAGAGAAAGAGGCTTATAGAGCTCTTTATGCG
CTTCTTTCAAAAGGGGAAGTGCCGCTTATAATCTTAACGATGATTGCAAGGCAGATAAGGCTTATTGCAAAGTTGAAATC
TCTAGAAGGAAAGGCTTTCGATAAAAAGTCTATAGCCAGTTACTTAGGCATTCCTTTCTTTGCTGTAGATGATATCGTAA
GGCAGAGCAAGCTTTTTACAAGAGAAGATTTGTATAAGGCGTACAAAGAGTGTTTGAGGTGCGACATAGCATTAAAAAGC
GGAACAGAGCCTTCATTTGCGCTGGAAAATCTCATAAAAAAATTATGCAAGCAATAA

Upstream 100 bases:

>100_bases
AGAGAGGAAAGTTGTACAGGACAGATGAAAATGGTGCTGTAATTGTAAGGACAGATGGAGTAAAGGCTCGCATATACCCC
TTTTTAAAAGGAGTGAAAGA

Downstream 100 bases:

>100_bases
AAAAGCGTACTTTGAAGGTACGCTTTATTCATTGCTTGCAGATTTTAGCAGAGCGTTAAATTTTGCATAAAGCTTCGATT
TTTTCCTGGCAGCAGTGTTT

Product: DNA polymerase III delta subunit

Products: diphosphate; DNAn+1

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MNYREFVESIKKGQIAPLYLFYGEERFLLLDAVKRLKARLLVPEFEDMNYIVIERENPEEYVEAIIENCETLPFFSNYKI
VVVKNEEEQLSKIGDKELKRLTDYFKNRVLGNTSLVVVVVSGEKIDSRKKLYKFMEKEAAVVEFKKLTPEEAVNYAGYFL
KKHGKKAAKKDVESLVKNIGTDLYSIVNELEKVIAYSEGETLDLEEAREVLSVTLQQNVFHLVNAIGMKKEKEAYRALYA
LLSKGEVPLIILTMIARQIRLIAKLKSLEGKAFDKKSIASYLGIPFFAVDDIVRQSKLFTREDLYKAYKECLRCDIALKS
GTEPSFALENLIKKLCKQ

Sequences:

>Translated_338_residues
MNYREFVESIKKGQIAPLYLFYGEERFLLLDAVKRLKARLLVPEFEDMNYIVIERENPEEYVEAIIENCETLPFFSNYKI
VVVKNEEEQLSKIGDKELKRLTDYFKNRVLGNTSLVVVVVSGEKIDSRKKLYKFMEKEAAVVEFKKLTPEEAVNYAGYFL
KKHGKKAAKKDVESLVKNIGTDLYSIVNELEKVIAYSEGETLDLEEAREVLSVTLQQNVFHLVNAIGMKKEKEAYRALYA
LLSKGEVPLIILTMIARQIRLIAKLKSLEGKAFDKKSIASYLGIPFFAVDDIVRQSKLFTREDLYKAYKECLRCDIALKS
GTEPSFALENLIKKLCKQ
>Mature_338_residues
MNYREFVESIKKGQIAPLYLFYGEERFLLLDAVKRLKARLLVPEFEDMNYIVIERENPEEYVEAIIENCETLPFFSNYKI
VVVKNEEEQLSKIGDKELKRLTDYFKNRVLGNTSLVVVVVSGEKIDSRKKLYKFMEKEAAVVEFKKLTPEEAVNYAGYFL
KKHGKKAAKKDVESLVKNIGTDLYSIVNELEKVIAYSEGETLDLEEAREVLSVTLQQNVFHLVNAIGMKKEKEAYRALYA
LLSKGEVPLIILTMIARQIRLIAKLKSLEGKAFDKKSIASYLGIPFFAVDDIVRQSKLFTREDLYKAYKECLRCDIALKS
GTEPSFALENLIKKLCKQ

Specific function: Unknown

COG id: COG1466

COG function: function code L; DNA polymerase III, delta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008921
- InterPro:   IPR010372
- InterPro:   IPR005790 [H]

Pfam domain/function: PF06144 DNA_pol3_delta [H]

EC number: 2.7.7.7

Molecular weight: Translated: 38905; Mature: 38905

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYREFVESIKKGQIAPLYLFYGEERFLLLDAVKRLKARLLVPEFEDMNYIVIERENPEE
CCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHH
YVEAIIENCETLPFFSNYKIVVVKNEEEQLSKIGDKELKRLTDYFKNRVLGNTSLVVVVV
HHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEE
SGEKIDSRKKLYKFMEKEAAVVEFKKLTPEEAVNYAGYFLKKHGKKAAKKDVESLVKNIG
ECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
TDLYSIVNELEKVIAYSEGETLDLEEAREVLSVTLQQNVFHLVNAIGMKKEKEAYRALYA
HHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLSKGEVPLIILTMIARQIRLIAKLKSLEGKAFDKKSIASYLGIPFFAVDDIVRQSKLFT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
REDLYKAYKECLRCDIALKSGTEPSFALENLIKKLCKQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNYREFVESIKKGQIAPLYLFYGEERFLLLDAVKRLKARLLVPEFEDMNYIVIERENPEE
CCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHH
YVEAIIENCETLPFFSNYKIVVVKNEEEQLSKIGDKELKRLTDYFKNRVLGNTSLVVVVV
HHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEEE
SGEKIDSRKKLYKFMEKEAAVVEFKKLTPEEAVNYAGYFLKKHGKKAAKKDVESLVKNIG
ECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHC
TDLYSIVNELEKVIAYSEGETLDLEEAREVLSVTLQQNVFHLVNAIGMKKEKEAYRALYA
HHHHHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLSKGEVPLIILTMIARQIRLIAKLKSLEGKAFDKKSIASYLGIPFFAVDDIVRQSKLFT
HHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
REDLYKAYKECLRCDIALKSGTEPSFALENLIKKLCKQ
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxynucleoside triphosphate; DNAn

Specific reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]