Click here to switch to the map view.

The map label for this gene is MltE2 [H]

Identifier: 20807364

GI number: 20807364

Start: 895418

End: 895975

Strand: Reverse

Name: MltE2 [H]

Synonym: TTE0883

Alternate gene names: 20807364

Gene position: 895975-895418 (Counterclockwise)

Preceding gene: 20807406

Following gene: 20807352

Centisome position: 33.31

GC content: 34.05

Gene sequence:

>558_bases
TTGTCGAATTATAAAAGTGAGGTGAAAAAAATTATGATTGACAGCGTAATAAACAGCATAATTGAGGAAAAATTTAAGGA
AATACAGAGTAGACTCCCAGCCAATGTAAAAATATTTAGCACATCCTTAAATTTTCAAGAAATATTAAATAGCGAAATAG
AGAATATCAATCAAAAGGATTCTCCCTCTGAAATTGAAAAACTAATACGAGAAGCCAGTCAAAAATATGGAGTAGACGCA
AACCTCATAAGGTCAGTCATAAAAGCCGAATCCAACTTCAATCAGTTTGCTGTATCCCCTAAAGGAGCAATGGGTTTGAT
GCAGCTCATGCCATCCACGGCAAAGGAATTAAATGTAAAAAATCCTTTCGACCCTTCTCAAAACATAGACGGAGGAGTGA
GATACCTAAAAAATTTACTAGATACATATAAAGATGTAAGATTGGCTCTTGCTGCTTACAATGCAGGTCCTCAAGCTGTA
GAAAAATACCAAGGCATTCCCCCTTACCCTGAAACTATAAATTACATAAACAAAATTTTAAATGACTTGTATAAATAA

Upstream 100 bases:

>100_bases
TACACCTATATTATACTATACTTTTTCTAAAAATCCTTTAAAAATTTTTTCTAGGCCTTTTTTACTATTTTGCTCACAAA
AAAGAGGTATTTGAAATTTT

Downstream 100 bases:

>100_bases
AAGGGAGCCAAAAGGCTCCATTTCTATTTTTGTTTTGCACTTTTGTACCTCTGCTGGGAATCCAAAATTTTCTTTCTTAT
TCTTATGCTCTGAGGCGTAA

Product: lytic murein transglycosylase

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSNYKSEVKKIMIDSVINSIIEEKFKEIQSRLPANVKIFSTSLNFQEILNSEIENINQKDSPSEIEKLIREASQKYGVDA
NLIRSVIKAESNFNQFAVSPKGAMGLMQLMPSTAKELNVKNPFDPSQNIDGGVRYLKNLLDTYKDVRLALAAYNAGPQAV
EKYQGIPPYPETINYINKILNDLYK

Sequences:

>Translated_185_residues
MSNYKSEVKKIMIDSVINSIIEEKFKEIQSRLPANVKIFSTSLNFQEILNSEIENINQKDSPSEIEKLIREASQKYGVDA
NLIRSVIKAESNFNQFAVSPKGAMGLMQLMPSTAKELNVKNPFDPSQNIDGGVRYLKNLLDTYKDVRLALAAYNAGPQAV
EKYQGIPPYPETINYINKILNDLYK
>Mature_184_residues
SNYKSEVKKIMIDSVINSIIEEKFKEIQSRLPANVKIFSTSLNFQEILNSEIENINQKDSPSEIEKLIREASQKYGVDAN
LIRSVIKAESNFNQFAVSPKGAMGLMQLMPSTAKELNVKNPFDPSQNIDGGVRYLKNLLDTYKDVRLALAAYNAGPQAVE
KYQGIPPYPETINYINKILNDLYK

Specific function: Murein-Degrading Enzyme. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division (By Similarity). [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082191, Length=112, Percent_Identity=37.5, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 20909; Mature: 20778

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYKSEVKKIMIDSVINSIIEEKFKEIQSRLPANVKIFSTSLNFQEILNSEIENINQKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCC
SPSEIEKLIREASQKYGVDANLIRSVIKAESNFNQFAVSPKGAMGLMQLMPSTAKELNVK
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NPFDPSQNIDGGVRYLKNLLDTYKDVRLALAAYNAGPQAVEKYQGIPPYPETINYINKIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
NDLYK
HHHCC
>Mature Secondary Structure 
SNYKSEVKKIMIDSVINSIIEEKFKEIQSRLPANVKIFSTSLNFQEILNSEIENINQKD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCC
SPSEIEKLIREASQKYGVDANLIRSVIKAESNFNQFAVSPKGAMGLMQLMPSTAKELNVK
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
NPFDPSQNIDGGVRYLKNLLDTYKDVRLALAAYNAGPQAVEKYQGIPPYPETINYINKIL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHH
NDLYK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]