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The map label for this gene is DapD

Identifier: 20807312

GI number: 20807312

Start: 837196

End: 837921

Strand: Reverse

Name: DapD

Synonym: TTE0830

Alternate gene names: 20807312

Gene position: 837921-837196 (Counterclockwise)

Preceding gene: 20807313

Following gene: 20807308

Centisome position: 31.16

GC content: 39.67

Gene sequence:

>726_bases
ATGATAAACTTGAACACAAATGATAACCTGACGAACGCCTATGAAATTGCAAGATACATCAAAGAAGCAAAAAAATCCAC
TCCAGTAAAGGCATATGTACAGGGGAAGATCCAGGTAGAAGAAGAGGAAGGATTGAAAATATTTGGCTCTGAAGACTTTA
AAATACTCATTGGAGAATTAGAAGTTGTAGAAAAAGTCATAGAGCAAAACAAAGACAGAATAAAGTATTATCACTTGGAA
TATGACAGAAGAAACTCAGCAATACCACTTTTAGATATAACCCATCTGGATGCAAGAATAGAACCGGGAGCAATAATAAG
AGATAAAGTCAAAATAGGCAAAAACGCTGTGATAATGATGGGAGCAGTTATAAACATAGGAGCAGAAATCGGCGAAAACT
CAATGATAGATATGAACGCTGTGATAGGCGCAAGAGGTATCATAGGGAAAAACGTCCATGTTGGTGCAGGAGCTGTTATA
GCAGGAGTTCTAGAACCTCCAAGCAGTGTACCTGTTGTAATTGAAGACAATGTAATGATTGGGGCAAATGCTGTGATATT
GGAGGGCGTCAGAGTAGGCCGCGGCGCTGTGGTCGCAGCAGGCTCAGTGGTAATTGAAGATGTACCACCTAATACAGTGG
TGGCAGGTGTACCTGCTAAAATCGTCAAAGTAGTAGACGAAAAAACCAGGGAAAAAACAAAATTAATGGAAGACTTAAGA
GGTTAA

Upstream 100 bases:

>100_bases
AGTCAAGGGAAGTCTTTGGATATGGAGCTTTAAAAGCAGCTAAATTTTTAATAGGTCAAAAACCTGGCTTATATACAATG
GAAGACCTTGTAAAGAAAGG

Downstream 100 bases:

>100_bases
AACAAAACACCCGAGTTTTCGGGTGTTTTTTCTGACCTTTTTATTCTGTTTTTTGCAATTCTTTTTCCACTACCTCCATG
CGGGTTATAGATACTTCATA

Product: tetrahydrodipicolinate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MINLNTNDNLTNAYEIARYIKEAKKSTPVKAYVQGKIQVEEEEGLKIFGSEDFKILIGELEVVEKVIEQNKDRIKYYHLE
YDRRNSAIPLLDITHLDARIEPGAIIRDKVKIGKNAVIMMGAVINIGAEIGENSMIDMNAVIGARGIIGKNVHVGAGAVI
AGVLEPPSSVPVVIEDNVMIGANAVILEGVRVGRGAVVAAGSVVIEDVPPNTVVAGVPAKIVKVVDEKTREKTKLMEDLR
G

Sequences:

>Translated_241_residues
MINLNTNDNLTNAYEIARYIKEAKKSTPVKAYVQGKIQVEEEEGLKIFGSEDFKILIGELEVVEKVIEQNKDRIKYYHLE
YDRRNSAIPLLDITHLDARIEPGAIIRDKVKIGKNAVIMMGAVINIGAEIGENSMIDMNAVIGARGIIGKNVHVGAGAVI
AGVLEPPSSVPVVIEDNVMIGANAVILEGVRVGRGAVVAAGSVVIEDVPPNTVVAGVPAKIVKVVDEKTREKTKLMEDLR
G
>Mature_241_residues
MINLNTNDNLTNAYEIARYIKEAKKSTPVKAYVQGKIQVEEEEGLKIFGSEDFKILIGELEVVEKVIEQNKDRIKYYHLE
YDRRNSAIPLLDITHLDARIEPGAIIRDKVKIGKNAVIMMGAVINIGAEIGENSMIDMNAVIGARGIIGKNVHVGAGAVI
AGVLEPPSSVPVVIEDNVMIGANAVILEGVRVGRGAVVAAGSVVIEDVPPNTVVAGVPAKIVKVVDEKTREKTKLMEDLR
G

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=169, Percent_Identity=36.6863905325444, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1786537, Length=143, Percent_Identity=30.0699300699301, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790035, Length=106, Percent_Identity=39.622641509434, Blast_Score=64, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6322243, Length=116, Percent_Identity=38.7931034482759, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_THETN (Q8RBI7)

Other databases:

- EMBL:   AE008691
- RefSeq:   NP_622483.1
- HSSP:   P43886
- ProteinModelPortal:   Q8RBI7
- SMR:   Q8RBI7
- GeneID:   996959
- GenomeReviews:   AE008691_GR
- KEGG:   tte:TTE0830
- NMPDR:   fig|273068.3.peg.1080
- HOGENOM:   HBG704071
- OMA:   KNAVIMM
- ProtClustDB:   CLSK2754734
- BioCyc:   TTEN273068:TTE0830-MONOMER
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; PF00132 Hexapep; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 26028; Mature: 26028

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLNTNDNLTNAYEIARYIKEAKKSTPVKAYVQGKIQVEEEEGLKIFGSEDFKILIGEL
CEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEECCCCEEEEEHHH
EVVEKVIEQNKDRIKYYHLEYDRRNSAIPLLDITHLDARIEPGAIIRDKVKIGKNAVIMM
HHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEHHHHCCCCEEEEE
GAVINIGAEIGENSMIDMNAVIGARGIIGKNVHVGAGAVIAGVLEPPSSVPVVIEDNVMI
EHHEECCHHCCCCCEEEHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEECCEEE
GANAVILEGVRVGRGAVVAAGSVVIEDVPPNTVVAGVPAKIVKVVDEKTREKTKLMEDLR
CCCEEEEECEEECCCEEEEECEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHC
G
C
>Mature Secondary Structure
MINLNTNDNLTNAYEIARYIKEAKKSTPVKAYVQGKIQVEEEEGLKIFGSEDFKILIGEL
CEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCEEEECCCCEEEEEHHH
EVVEKVIEQNKDRIKYYHLEYDRRNSAIPLLDITHLDARIEPGAIIRDKVKIGKNAVIMM
HHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEHHHHCCCCEEEEE
GAVINIGAEIGENSMIDMNAVIGARGIIGKNVHVGAGAVIAGVLEPPSSVPVVIEDNVMI
EHHEECCHHCCCCCEEEHHHHHCCCCCCCCCEEECCCCEEEEECCCCCCCCEEEECCEEE
GANAVILEGVRVGRGAVVAAGSVVIEDVPPNTVVAGVPAKIVKVVDEKTREKTKLMEDLR
CCCEEEEECEEECCCEEEEECEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336