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The map label for this gene is PurR7 [H]

Identifier: 20807285

GI number: 20807285

Start: 800966

End: 801979

Strand: Direct

Name: PurR7 [H]

Synonym: TTE0803

Alternate gene names: 20807285

Gene position: 800966-801979 (Clockwise)

Preceding gene: 20807284

Following gene: 20807286

Centisome position: 29.78

GC content: 38.07

Gene sequence:

>1014_bases
ATGGCGACAATAGATGATGTAGCAAAATTAGCAGGGGTTTCAATTGCAACAGTATCGAGGGTATTCAACAACAGTCCCTG
GGTAAGTGAAAAAACTAGGGAAAAAGTTTTAAAAGCAGCAGAAGAGCTGGGGTATAAGCCCAGCATGCCAGCGAGAAGCC
TGGCGATGAAAAAGACAAATACTATTGGTTTGATTGTGCCAGATATATCAAACCCTTATTATGCAGAGGTTGTGAGGGGT
ATCGAAGACGTTTGCAATATTTACAAGTATAACATTATACTTTGCAACGCAGATAATAAAAGAGAAAAAGAGTTTCAATA
TATAGATATGTTGAAAAACAGGTGGGTAGATGGCGTAATATTTCACTGCGATTATTTTTCAGAGGAGCATTACGAGGTTT
TTAAAAACAGTAATTTAAAAGTGGTCTTGGCAGGCAGGACTACAAAATTTGATGTCCCTTATGTTGGAATTGACAATTTT
AAAGCGGCTTATGATGCGGTAAATTACTTAATTTCACTTGGCCATAAAAGGATAGGTATTATTCACGGACCTTTAGATGA
TATGAAGGAAACTATTGATAGTGTAGACAGGCTTAACGGCTATAAACAAGCTCTCATCGACAACGGTTTGCCGATTTATG
ATGAACTTGTGAAGGAGGCAAACTTCAAGTATAAAGGCGGATATAGCGCTGCTATGGAAATGCTAAAGGGAAATGTTAGG
CCTACTGCTATTTTTGCAATAAGCGATATCATGGCTATGGGGGCTATAAATGCTGTGTTTGATAAAGGGCTTTCCTGCCC
GGAGGATGTTTCTGTAATTGGATTTGACAATATTGATTTGTCGGAAGCTACAAGGCCTCCGCTTACGACTGTATCTCAGC
CGATGTATGAGATAGGAGCTATTGCAGCAAGGATGCTTATAAAAATTATAAATGGTGAGAATTTGGAGAGTTCTCAAGTT
ATATTGAAACACAAATTGGTTTTGAGAAATTCTGTAATTCCTTTAAGGAGTTGA

Upstream 100 bases:

>100_bases
AAGGGGAATAATTTTTTATAAATTCCTCTTGAAATTTTGTGAAGATGATAATATAATATAACTGTAAGCGGTTACAGTAA
ATCTGGAAAAGGGTGTTAAG

Downstream 100 bases:

>100_bases
ATTTCTTTTATTTTTAAAACTGTAAGCGCTTTCAATATCAAGCATATCAAATGAGTTAAGAAGGAAAGGAGTAGTAATGA
ATGACTGTGACTGAATTTGT

Product: transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MATIDDVAKLAGVSIATVSRVFNNSPWVSEKTREKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRG
IEDVCNIYKYNIILCNADNKREKEFQYIDMLKNRWVDGVIFHCDYFSEEHYEVFKNSNLKVVLAGRTTKFDVPYVGIDNF
KAAYDAVNYLISLGHKRIGIIHGPLDDMKETIDSVDRLNGYKQALIDNGLPIYDELVKEANFKYKGGYSAAMEMLKGNVR
PTAIFAISDIMAMGAINAVFDKGLSCPEDVSVIGFDNIDLSEATRPPLTTVSQPMYEIGAIAARMLIKIINGENLESSQV
ILKHKLVLRNSVIPLRS

Sequences:

>Translated_337_residues
MATIDDVAKLAGVSIATVSRVFNNSPWVSEKTREKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRG
IEDVCNIYKYNIILCNADNKREKEFQYIDMLKNRWVDGVIFHCDYFSEEHYEVFKNSNLKVVLAGRTTKFDVPYVGIDNF
KAAYDAVNYLISLGHKRIGIIHGPLDDMKETIDSVDRLNGYKQALIDNGLPIYDELVKEANFKYKGGYSAAMEMLKGNVR
PTAIFAISDIMAMGAINAVFDKGLSCPEDVSVIGFDNIDLSEATRPPLTTVSQPMYEIGAIAARMLIKIINGENLESSQV
ILKHKLVLRNSVIPLRS
>Mature_336_residues
ATIDDVAKLAGVSIATVSRVFNNSPWVSEKTREKVLKAAEELGYKPSMPARSLAMKKTNTIGLIVPDISNPYYAEVVRGI
EDVCNIYKYNIILCNADNKREKEFQYIDMLKNRWVDGVIFHCDYFSEEHYEVFKNSNLKVVLAGRTTKFDVPYVGIDNFK
AAYDAVNYLISLGHKRIGIIHGPLDDMKETIDSVDRLNGYKQALIDNGLPIYDELVKEANFKYKGGYSAAMEMLKGNVRP
TAIFAISDIMAMGAINAVFDKGLSCPEDVSVIGFDNIDLSEATRPPLTTVSQPMYEIGAIAARMLIKIINGENLESSQVI
LKHKLVLRNSVIPLRS

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=37.9518072289157, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=36.9369369369369, Blast_Score=214, Evalue=5e-57,
Organism=Escherichia coli, GI1787948, Length=342, Percent_Identity=37.4269005847953, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1788474, Length=336, Percent_Identity=33.6309523809524, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789202, Length=333, Percent_Identity=34.8348348348348, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=31.9526627218935, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=30.188679245283, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI48994940, Length=318, Percent_Identity=29.2452830188679, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787906, Length=337, Percent_Identity=29.9703264094956, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786540, Length=335, Percent_Identity=28.0597014925373, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1790715, Length=333, Percent_Identity=26.1261261261261, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789456, Length=314, Percent_Identity=28.6624203821656, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1786268, Length=303, Percent_Identity=25.7425742574257, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790689, Length=325, Percent_Identity=25.8461538461538, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37619; Mature: 37488

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIDDVAKLAGVSIATVSRVFNNSPWVSEKTREKVLKAAEELGYKPSMPARSLAMKKTN
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLIVPDISNPYYAEVVRGIEDVCNIYKYNIILCNADNKREKEFQYIDMLKNRWVDGVI
EEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FHCDYFSEEHYEVFKNSNLKVVLAGRTTKFDVPYVGIDNFKAAYDAVNYLISLGHKRIGI
EEEECCCHHHHHHHCCCCEEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHCCCEEEE
IHGPLDDMKETIDSVDRLNGYKQALIDNGLPIYDELVKEANFKYKGGYSAAMEMLKGNVR
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
PTAIFAISDIMAMGAINAVFDKGLSCPEDVSVIGFDNIDLSEATRPPLTTVSQPMYEIGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
IAARMLIKIINGENLESSQVILKHKLVLRNSVIPLRS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATIDDVAKLAGVSIATVSRVFNNSPWVSEKTREKVLKAAEELGYKPSMPARSLAMKKTN
CCHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
TIGLIVPDISNPYYAEVVRGIEDVCNIYKYNIILCNADNKREKEFQYIDMLKNRWVDGVI
EEEEEECCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEE
FHCDYFSEEHYEVFKNSNLKVVLAGRTTKFDVPYVGIDNFKAAYDAVNYLISLGHKRIGI
EEEECCCHHHHHHHCCCCEEEEEECCCEEECCCEECCCCHHHHHHHHHHHHHHCCCEEEE
IHGPLDDMKETIDSVDRLNGYKQALIDNGLPIYDELVKEANFKYKGGYSAAMEMLKGNVR
EECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
PTAIFAISDIMAMGAINAVFDKGLSCPEDVSVIGFDNIDLSEATRPPLTTVSQPMYEIGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
IAARMLIKIINGENLESSQVILKHKLVLRNSVIPLRS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]