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The map label for this gene is ProP2 [H]

Identifier: 20807234

GI number: 20807234

Start: 750974

End: 752368

Strand: Reverse

Name: ProP2 [H]

Synonym: TTE0749

Alternate gene names: 20807234

Gene position: 752368-750974 (Counterclockwise)

Preceding gene: 20807239

Following gene: 20807233

Centisome position: 27.97

GC content: 38.06

Gene sequence:

>1395_bases
ATGGCACAAAAACAATACAACAAATGGATTATACTATCTGCAGTAGTCATAGGAAGCATAATGGGCCCAATTGATGGAAG
TGTTGTAAATCTTGCAATGCCCGAATTCACAAAAATTTTTCACACAAACATAACTACAGTAAGCTGGGTTTCCATGATAT
ATCTCCTTGTTGTAAGCAGTTTAATGATGACATTTGGAAGGCTTGGAGACATACTAGGTTACAAAAAATTATATGAATAT
GGCCTTTTGACATTTTCTATCTCTTCTTTAATACTGAGTCTTTCTGCAAACATATATATGCTGATAATAATGAGAGCTAT
TCAAGCAGTAGGCGCAGCTATGCTCATGTCAATGTCTTCTGCAATAATCACCTCTGTATTTCCACCAAATGAAAGGGGTA
AGGCATTAGGCATTAACGCCATGGCAATTTCAATAGGCCTTGCAATTGGACCTACTCTGGGAGGTTTTCTCTTAAAATAT
TTGGGTTGGCCTTCTATATTTTACATAAACGTACCTATTGGTGTAATTGGCTACATTTGGGCCCATACAGTTGTACCTGA
AAACAAAGGAGTGCCAGAAAAATTTGACCCATATGGTTCCACCTACTTTTTTATGTTTTTAGCAAGCCTTTTGCTTTTTA
TATCAGAAGGTGGAACATGGGGCTGGTATTCAGTGCCAAGCATTTTTTCTTTCGCAGCTTTTTTAGTATTTCTCATACTC
TTCATCCGTACAGAAAACAAGGTTGAATTCCCTATGTTTGATTTCTCACTTTTTAAAATAAGGTCTTTCACCTTTGGAAT
CACAAGTACCCTTTTAAACTTTATGGCCCAGTACACGATGACCTTTTTAACCCCTTTTCTTCTGAAACATCTGGGCTACT
CTACTGAAAAAGCAGGCATAATTATGACCTCCTTCCCTGCAATGATGTTTATTGTAGCTCCTTTAAGCGGAATTCTAGCC
GATATGTATGGAGCCCAAATCCTCTCAACTATCGGCGCATTAATTTCGGCTCTGGCTCTCTTTTTAATGGCTACTCTCAC
AGAAAAATCGTCCATGTTTGATATCATGTGGCGTCTTGCTATATTTGGAATAGGAAATGCCATTTTCCAAACTCCTAACA
ACAGCGCGGTAATGGGAAGCACTCCTAAAAATAGACTAGGTATAGCTTCTGCCTCCCTTGCCACGATGAGAAATGTAGGA
ATGGTAATTGGAATCGCTGTAGCCGGTGCAATTTTCACCAACAGGTTAAAAGCCTATCAAGCTTTTAACTTGCCCTATAA
CATTTCATTTATGAGGGCAATTAAAGAAGCATACATAGTTGCAGGAATTTTTTCTGTAATCTGCGCCTTTACTTCTCTTG
TCAGAGACAATATCAAAATACAAAGAAAGGATTGA

Upstream 100 bases:

>100_bases
CTTTAAATTCCCCTATAATTATAGTTTACAATGCCTTTTTTTTCAACATTTATCTTTTGCCAAACTTTGTGATATAATTT
ATTTCGATGGAGGGGTACAA

Downstream 100 bases:

>100_bases
TTTTTATGGAAGTGACTTTGGCTATTGTAAAGCCGGATGGAGTAAAGAGGGGTCTTATAGGGGAAATACTGAAAAGATAT
GAAAACAAGGGGTTAAGGCT

Product: major facilitator superfamily permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MAQKQYNKWIILSAVVIGSIMGPIDGSVVNLAMPEFTKIFHTNITTVSWVSMIYLLVVSSLMMTFGRLGDILGYKKLYEY
GLLTFSISSLILSLSANIYMLIIMRAIQAVGAAMLMSMSSAIITSVFPPNERGKALGINAMAISIGLAIGPTLGGFLLKY
LGWPSIFYINVPIGVIGYIWAHTVVPENKGVPEKFDPYGSTYFFMFLASLLLFISEGGTWGWYSVPSIFSFAAFLVFLIL
FIRTENKVEFPMFDFSLFKIRSFTFGITSTLLNFMAQYTMTFLTPFLLKHLGYSTEKAGIIMTSFPAMMFIVAPLSGILA
DMYGAQILSTIGALISALALFLMATLTEKSSMFDIMWRLAIFGIGNAIFQTPNNSAVMGSTPKNRLGIASASLATMRNVG
MVIGIAVAGAIFTNRLKAYQAFNLPYNISFMRAIKEAYIVAGIFSVICAFTSLVRDNIKIQRKD

Sequences:

>Translated_464_residues
MAQKQYNKWIILSAVVIGSIMGPIDGSVVNLAMPEFTKIFHTNITTVSWVSMIYLLVVSSLMMTFGRLGDILGYKKLYEY
GLLTFSISSLILSLSANIYMLIIMRAIQAVGAAMLMSMSSAIITSVFPPNERGKALGINAMAISIGLAIGPTLGGFLLKY
LGWPSIFYINVPIGVIGYIWAHTVVPENKGVPEKFDPYGSTYFFMFLASLLLFISEGGTWGWYSVPSIFSFAAFLVFLIL
FIRTENKVEFPMFDFSLFKIRSFTFGITSTLLNFMAQYTMTFLTPFLLKHLGYSTEKAGIIMTSFPAMMFIVAPLSGILA
DMYGAQILSTIGALISALALFLMATLTEKSSMFDIMWRLAIFGIGNAIFQTPNNSAVMGSTPKNRLGIASASLATMRNVG
MVIGIAVAGAIFTNRLKAYQAFNLPYNISFMRAIKEAYIVAGIFSVICAFTSLVRDNIKIQRKD
>Mature_463_residues
AQKQYNKWIILSAVVIGSIMGPIDGSVVNLAMPEFTKIFHTNITTVSWVSMIYLLVVSSLMMTFGRLGDILGYKKLYEYG
LLTFSISSLILSLSANIYMLIIMRAIQAVGAAMLMSMSSAIITSVFPPNERGKALGINAMAISIGLAIGPTLGGFLLKYL
GWPSIFYINVPIGVIGYIWAHTVVPENKGVPEKFDPYGSTYFFMFLASLLLFISEGGTWGWYSVPSIFSFAAFLVFLILF
IRTENKVEFPMFDFSLFKIRSFTFGITSTLLNFMAQYTMTFLTPFLLKHLGYSTEKAGIIMTSFPAMMFIVAPLSGILAD
MYGAQILSTIGALISALALFLMATLTEKSSMFDIMWRLAIFGIGNAIFQTPNNSAVMGSTPKNRLGIASASLATMRNVGM
VIGIAVAGAIFTNRLKAYQAFNLPYNISFMRAIKEAYIVAGIFSVICAFTSLVRDNIKIQRKD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=400, Percent_Identity=31.5, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1790195, Length=462, Percent_Identity=25.7575757575758, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789042, Length=413, Percent_Identity=26.3922518159806, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788710, Length=418, Percent_Identity=25.5980861244019, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1788392, Length=304, Percent_Identity=26.6447368421053, Blast_Score=89, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6325455, Length=142, Percent_Identity=35.2112676056338, Blast_Score=77, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323735, Length=331, Percent_Identity=23.2628398791541, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=185, Percent_Identity=27.5675675675676, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319770, Length=142, Percent_Identity=30.9859154929577, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321663, Length=150, Percent_Identity=29.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324954, Length=233, Percent_Identity=26.6094420600858, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 51027; Mature: 50895

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQKQYNKWIILSAVVIGSIMGPIDGSVVNLAMPEFTKIFHTNITTVSWVSMIYLLVVSS
CCCCHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LMMTFGRLGDILGYKKLYEYGLLTFSISSLILSLSANIYMLIIMRAIQAVGAAMLMSMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AIITSVFPPNERGKALGINAMAISIGLAIGPTLGGFLLKYLGWPSIFYINVPIGVIGYIW
HHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AHTVVPENKGVPEKFDPYGSTYFFMFLASLLLFISEGGTWGWYSVPSIFSFAAFLVFLIL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FIRTENKVEFPMFDFSLFKIRSFTFGITSTLLNFMAQYTMTFLTPFLLKHLGYSTEKAGI
HHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IMTSFPAMMFIVAPLSGILADMYGAQILSTIGALISALALFLMATLTEKSSMFDIMWRLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGIGNAIFQTPNNSAVMGSTPKNRLGIASASLATMRNVGMVIGIAVAGAIFTNRLKAYQ
HHHCCHHHEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFNLPYNISFMRAIKEAYIVAGIFSVICAFTSLVRDNIKIQRKD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure 
AQKQYNKWIILSAVVIGSIMGPIDGSVVNLAMPEFTKIFHTNITTVSWVSMIYLLVVSS
CCCHHCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LMMTFGRLGDILGYKKLYEYGLLTFSISSLILSLSANIYMLIIMRAIQAVGAAMLMSMSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHH
AIITSVFPPNERGKALGINAMAISIGLAIGPTLGGFLLKYLGWPSIFYINVPIGVIGYIW
HHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHH
AHTVVPENKGVPEKFDPYGSTYFFMFLASLLLFISEGGTWGWYSVPSIFSFAAFLVFLIL
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FIRTENKVEFPMFDFSLFKIRSFTFGITSTLLNFMAQYTMTFLTPFLLKHLGYSTEKAGI
HHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IMTSFPAMMFIVAPLSGILADMYGAQILSTIGALISALALFLMATLTEKSSMFDIMWRLA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFGIGNAIFQTPNNSAVMGSTPKNRLGIASASLATMRNVGMVIGIAVAGAIFTNRLKAYQ
HHHCCHHHEECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFNLPYNISFMRAIKEAYIVAGIFSVICAFTSLVRDNIKIQRKD
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]