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The map label for this gene is groES [H]

Identifier: 20807075

GI number: 20807075

Start: 580037

End: 580321

Strand: Direct

Name: groES [H]

Synonym: TTE0579

Alternate gene names: 20807075

Gene position: 580037-580321 (Clockwise)

Preceding gene: 20807074

Following gene: 20807076

Centisome position: 21.57

GC content: 42.46

Gene sequence:

>285_bases
ATGAGACTAAAGCCACTCGGAGACAGAGTAGTAGTTAAGGTTATTCAGTCTGAAGAAGTCACAAAAGGCGGAGTTATTCT
ACCGGGCACAGCTAAGGAGAAACCGCAACAAGGAGAAGTTGTGGCAGTAGGACCAGGTCAATACATAGATGGGAAAAGAG
TAGAGCCAGAAGTCAAAGTTGGCGATAGAGTGATTTTCTCCAAGTACGCTGGGACGGAAGTTAAATTGGATGGCGAAGAA
TATTTACTTTTAAGAGAGAGCGATATTCTAGCAATAATCGAATAA

Upstream 100 bases:

>100_bases
TCAGGTTTGATATGTTTTACCACTTAAATTAATATAGAGATTGGAATTAGCACTCATAGAAGTTGAGTGCTAACAAAGGA
AGGAGGAGGGATAAAGGTAT

Downstream 100 bases:

>100_bases
GGAGGTAGTGAAAATGGCAAAACAGATCAAATACGGTGAGGAAGCGCGCAAGGCTTTAGAAAGAGGAGTTAATGCTGTTG
CTAATACTGTGAAGGTAACA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MRLKPLGDRVVVKVIQSEEVTKGGVILPGTAKEKPQQGEVVAVGPGQYIDGKRVEPEVKVGDRVIFSKYAGTEVKLDGEE
YLLLRESDILAIIE

Sequences:

>Translated_94_residues
MRLKPLGDRVVVKVIQSEEVTKGGVILPGTAKEKPQQGEVVAVGPGQYIDGKRVEPEVKVGDRVIFSKYAGTEVKLDGEE
YLLLRESDILAIIE
>Mature_94_residues
MRLKPLGDRVVVKVIQSEEVTKGGVILPGTAKEKPQQGEVVAVGPGQYIDGKRVEPEVKVGDRVIFSKYAGTEVKLDGEE
YLLLRESDILAIIE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=90, Percent_Identity=46.6666666666667, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=47.9166666666667, Blast_Score=82, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=40.8602150537634, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=91, Percent_Identity=45.0549450549451, Blast_Score=72, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=44.0860215053763, Blast_Score=69, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=42.5531914893617, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10276; Mature: 10276

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKPLGDRVVVKVIQSEEVTKGGVILPGTAKEKPQQGEVVAVGPGQYIDGKRVEPEVKV
CCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDRVIFSKYAGTEVKLDGEEYLLLRESDILAIIE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MRLKPLGDRVVVKVIQSEEVTKGGVILPGTAKEKPQQGEVVAVGPGQYIDGKRVEPEVKV
CCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCC
GDRVIFSKYAGTEVKLDGEEYLLLRESDILAIIE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9795109; 7912671 [H]