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The map label for this gene is FabH [H]

Identifier: 20807054

GI number: 20807054

Start: 559633

End: 560661

Strand: Direct

Name: FabH [H]

Synonym: TTE0553

Alternate gene names: 20807054

Gene position: 559633-560661 (Clockwise)

Preceding gene: 20807053

Following gene: 20807055

Centisome position: 20.81

GC content: 37.03

Gene sequence:

>1029_bases
ATGGGAAGAAAAAATGTTAATGTAGGAATTGTGGGAACAGGACTTTATATTCCTCAAACGTACATGACATCTGAAGATAT
AGCTAGAGAGACAGGAATACCCGAGGAGATTATAAGAACCAAATTTGGGATTATAAAGAAACCTATACCGGGACCGGAGG
ACCATACTTGCTATATGGGAATACAAGCGGCTAAAGATTGTCTTAAAAGGACTGGTGTCGATCCGAAGGAGATAGACCTT
ATTATATATATAGGCGAGGAACATAAGGAATATCTACTTTGGACCTCTGGTATCAAATTGCAGTATGAGATAGGTGCAGA
GAATGCGTGGGCTTTTGACATGGCTTTGAGATGTGGTACGGCAGTTGCTGCACTGAAGATAGCAAAAGATATGATGATTG
CAGATGACAATATCAACACTGTTTTAATTGCTGGTGGTTATAGAAATGTTGACTTTATTGACTATAAAAATCCCCGAGTA
TCTTTCATGTATGACCTTGCCGCAGGAGGAGGGGCAATTCTTCTTAAGAAAAATTATAATAGAAATATTGTACTTGAAGC
ATCAATTATAACAGATGGCTCCTTTTCTGAAGATGTTGCTGTTGTTGGTGGTGGAACAAAGTATCCAGTAAGTCATGAAA
TGATTGATAAAGGACTATATAAATTAGATGTGTTAAATCCGGAACATATGAGGAAAGGATTGGAAGAAAAATCGATGCCT
AATTTTTTACATGTGATTAAAGAATCTTTAAGAAAAAGTGGTTATACGCCTTCCGATATTGGCTATCTTGCGATACTTCA
CATGAAAAGGTCTGCTCATGAATTTATTTTAAATGAACTAGGTTTATCTCCTGATAAATCGATTTACTTAGAGAACTATG
GACATATGGGACAGATCGATCAAATACTTTCAACACATCTTGCCCTGGAAGAAGGGAAAATAAAAGATGGCGATGTAGTA
GTATGGGTAAGTGCGGGTATAGGATATGTATGGGATGCAATAACGATAAAATGGGGACCTATAGAGTAA

Upstream 100 bases:

>100_bases
TGTTTAGTAATGCAGGACACATGTTTTTTATAGAAAAAGCAGAAGAAGTGAATCGGAAAATTATAGAGTTCTTAACAAAA
CCTATAGGAGGAGATAAAAA

Downstream 100 bases:

>100_bases
ATTTTATAGCATAAATTTTACGGCAGGAGGTTTTGAAAATGGACTATAAAGAACTGTACAAGAGAAAACTAGTTTCGGTA
GAAGAAATTTTATCAAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MGRKNVNVGIVGTGLYIPQTYMTSEDIARETGIPEEIIRTKFGIIKKPIPGPEDHTCYMGIQAAKDCLKRTGVDPKEIDL
IIYIGEEHKEYLLWTSGIKLQYEIGAENAWAFDMALRCGTAVAALKIAKDMMIADDNINTVLIAGGYRNVDFIDYKNPRV
SFMYDLAAGGGAILLKKNYNRNIVLEASIITDGSFSEDVAVVGGGTKYPVSHEMIDKGLYKLDVLNPEHMRKGLEEKSMP
NFLHVIKESLRKSGYTPSDIGYLAILHMKRSAHEFILNELGLSPDKSIYLENYGHMGQIDQILSTHLALEEGKIKDGDVV
VWVSAGIGYVWDAITIKWGPIE

Sequences:

>Translated_342_residues
MGRKNVNVGIVGTGLYIPQTYMTSEDIARETGIPEEIIRTKFGIIKKPIPGPEDHTCYMGIQAAKDCLKRTGVDPKEIDL
IIYIGEEHKEYLLWTSGIKLQYEIGAENAWAFDMALRCGTAVAALKIAKDMMIADDNINTVLIAGGYRNVDFIDYKNPRV
SFMYDLAAGGGAILLKKNYNRNIVLEASIITDGSFSEDVAVVGGGTKYPVSHEMIDKGLYKLDVLNPEHMRKGLEEKSMP
NFLHVIKESLRKSGYTPSDIGYLAILHMKRSAHEFILNELGLSPDKSIYLENYGHMGQIDQILSTHLALEEGKIKDGDVV
VWVSAGIGYVWDAITIKWGPIE
>Mature_341_residues
GRKNVNVGIVGTGLYIPQTYMTSEDIARETGIPEEIIRTKFGIIKKPIPGPEDHTCYMGIQAAKDCLKRTGVDPKEIDLI
IYIGEEHKEYLLWTSGIKLQYEIGAENAWAFDMALRCGTAVAALKIAKDMMIADDNINTVLIAGGYRNVDFIDYKNPRVS
FMYDLAAGGGAILLKKNYNRNIVLEASIITDGSFSEDVAVVGGGTKYPVSHEMIDKGLYKLDVLNPEHMRKGLEEKSMPN
FLHVIKESLRKSGYTPSDIGYLAILHMKRSAHEFILNELGLSPDKSIYLENYGHMGQIDQILSTHLALEEGKIKDGDVVV
WVSAGIGYVWDAITIKWGPIE

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=339, Percent_Identity=22.1238938053097, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 37989; Mature: 37858

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRKNVNVGIVGTGLYIPQTYMTSEDIARETGIPEEIIRTKFGIIKKPIPGPEDHTCYMG
CCCCCEEEEEEECCEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
IQAAKDCLKRTGVDPKEIDLIIYIGEEHKEYLLWTSGIKLQYEIGAENAWAFDMALRCGT
HHHHHHHHHHCCCCHHHEEEEEEECCCCCEEEEEECCEEEEEEECCCCCEEEHHHHHHHH
AVAALKIAKDMMIADDNINTVLIAGGYRNVDFIDYKNPRVSFMYDLAAGGGAILLKKNYN
HHHHHHHHHHHEEECCCCCEEEEECCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCC
RNIVLEASIITDGSFSEDVAVVGGGTKYPVSHEMIDKGLYKLDVLNPEHMRKGLEEKSMP
CEEEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCHHHHHCCCHHCCCH
NFLHVIKESLRKSGYTPSDIGYLAILHMKRSAHEFILNELGLSPDKSIYLENYGHMGQID
HHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHH
QILSTHLALEEGKIKDGDVVVWVSAGIGYVWDAITIKWGPIE
HHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
GRKNVNVGIVGTGLYIPQTYMTSEDIARETGIPEEIIRTKFGIIKKPIPGPEDHTCYMG
CCCCEEEEEEECCEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEE
IQAAKDCLKRTGVDPKEIDLIIYIGEEHKEYLLWTSGIKLQYEIGAENAWAFDMALRCGT
HHHHHHHHHHCCCCHHHEEEEEEECCCCCEEEEEECCEEEEEEECCCCCEEEHHHHHHHH
AVAALKIAKDMMIADDNINTVLIAGGYRNVDFIDYKNPRVSFMYDLAAGGGAILLKKNYN
HHHHHHHHHHHEEECCCCCEEEEECCCCCCEEEECCCCCEEEEEEECCCCCEEEEEECCC
RNIVLEASIITDGSFSEDVAVVGGGTKYPVSHEMIDKGLYKLDVLNPEHMRKGLEEKSMP
CEEEEEEEEEECCCCCCCEEEEECCCCCCCCHHHHHCCCEEEECCCHHHHHCCCHHCCCH
NFLHVIKESLRKSGYTPSDIGYLAILHMKRSAHEFILNELGLSPDKSIYLENYGHMGQID
HHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHH
QILSTHLALEEGKIKDGDVVVWVSAGIGYVWDAITIKWGPIE
HHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA