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The map label for this gene is FixB [H]

Identifier: 20807048

GI number: 20807048

Start: 553368

End: 554375

Strand: Direct

Name: FixB [H]

Synonym: TTE0547

Alternate gene names: 20807048

Gene position: 553368-554375 (Clockwise)

Preceding gene: 20807047

Following gene: 20807049

Centisome position: 20.58

GC content: 42.86

Gene sequence:

>1008_bases
ATGAGCGAATATAAAGATATATGGGTGTTTGTTGAGCAAAGAGAACAGAAACTCATGAATGTTTCTTTAGAGATATTGGG
AGAGGCTCGAAGACTTGCAGATAAAAAAGGTGTAAAGGCTTGTGCTGTTTTGGTAGGATATGAAGTAAAAGGGCTGGCAG
AGGAATTGATAAAATACGGTGCTGATGTAGTGTATGTCATAGATCATCCTCTTCTTAAAAACTACACCACGGATGCCTAC
ACAAAAGTCATATGTGACCTTGCGAATAGCTTAAAGCCAGAGGTTATTTTATACGGCGCTACCTATATAGGAAGGGATTT
GGCACCGAGAATTGCAGCGAGAATGCGCACAGGACTTACGGCAGACTGTACAGCACTTGATATAGATGAAAATGGCCTTC
TTTTGCAGATAAGGCCTGCATTTGGCGGAAATTTAATCGCTACAATAATTTGTCCCGAAAGAAGGCCCCAAATGGCAACA
ATAAGGCCTGGCGTTATGAAGAAAGCTTTGATGGATGAAGGGCGCAGGGGAGAAGTAATTGAAATAAAACCAGTGATAGA
AGAAAAAGATATAAGGACAGAGATTATCAGTATAATAAAAGAGGCAAGGCAAAAGGTAAATTTAGAAGAAGCAGATATTA
TTGTATCTGGAGGAAGGGGAGTAGGGGGACCGGAAGGATTTAAATTGATTGAAGAGCTGGCGGAAGTGCTGGGAGGGGTT
GTAGGTGCTTCCCGCGCTGCGGTGGAGGCGGGGTGGATTTCTTCTGACCATCAGGTAGGGCAGACAGGGAAAACTGTAAG
GCCCAAGCTTTACATAGCCTGTGGAATTAGCGGAGCTATACAGCATATTGCAGGAATGGGTGGTGCAAAGACCATAGTTG
CTATAAATAAAAATCCCGATGCTCCCATCTTTAAGATAGCCGATTACGGCATAGTCGGAGATTTATTTAAGGTAATACCG
GCCCTGATAGAAGAAATAAAAGAGGCCAAGAAAAAGGCGATGGCATAA

Upstream 100 bases:

>100_bases
AGAGAGCAGGAGAGATTTTTACAGGCAATGTAAAAGAATGTGTACAAAACCTCGTTCAGAGATTAGTTGAAAAACATCTT
ATATGAAGGAGGCTGGAAAA

Downstream 100 bases:

>100_bases
AATTTGCATGTAATAAAGTAGTAGTGACTTATGTATGTTTATCAAGAAGGGCGGCTGACCTTTTGGCAGCTGACTCTTTT
ACAATAAATTTCTAGGAGGG

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSEYKDIWVFVEQREQKLMNVSLEILGEARRLADKKGVKACAVLVGYEVKGLAEELIKYGADVVYVIDHPLLKNYTTDAY
TKVICDLANSLKPEVILYGATYIGRDLAPRIAARMRTGLTADCTALDIDENGLLLQIRPAFGGNLIATIICPERRPQMAT
IRPGVMKKALMDEGRRGEVIEIKPVIEEKDIRTEIISIIKEARQKVNLEEADIIVSGGRGVGGPEGFKLIEELAEVLGGV
VGASRAAVEAGWISSDHQVGQTGKTVRPKLYIACGISGAIQHIAGMGGAKTIVAINKNPDAPIFKIADYGIVGDLFKVIP
ALIEEIKEAKKKAMA

Sequences:

>Translated_335_residues
MSEYKDIWVFVEQREQKLMNVSLEILGEARRLADKKGVKACAVLVGYEVKGLAEELIKYGADVVYVIDHPLLKNYTTDAY
TKVICDLANSLKPEVILYGATYIGRDLAPRIAARMRTGLTADCTALDIDENGLLLQIRPAFGGNLIATIICPERRPQMAT
IRPGVMKKALMDEGRRGEVIEIKPVIEEKDIRTEIISIIKEARQKVNLEEADIIVSGGRGVGGPEGFKLIEELAEVLGGV
VGASRAAVEAGWISSDHQVGQTGKTVRPKLYIACGISGAIQHIAGMGGAKTIVAINKNPDAPIFKIADYGIVGDLFKVIP
ALIEEIKEAKKKAMA
>Mature_334_residues
SEYKDIWVFVEQREQKLMNVSLEILGEARRLADKKGVKACAVLVGYEVKGLAEELIKYGADVVYVIDHPLLKNYTTDAYT
KVICDLANSLKPEVILYGATYIGRDLAPRIAARMRTGLTADCTALDIDENGLLLQIRPAFGGNLIATIICPERRPQMATI
RPGVMKKALMDEGRRGEVIEIKPVIEEKDIRTEIISIIKEARQKVNLEEADIIVSGGRGVGGPEGFKLIEELAEVLGGVV
GASRAAVEAGWISSDHQVGQTGKTVRPKLYIACGISGAIQHIAGMGGAKTIVAINKNPDAPIFKIADYGIVGDLFKVIPA
LIEEIKEAKKKAMA

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=332, Percent_Identity=36.7469879518072, Blast_Score=191, Evalue=7e-49,
Organism=Homo sapiens, GI189181759, Length=286, Percent_Identity=39.5104895104895, Blast_Score=183, Evalue=2e-46,
Organism=Escherichia coli, GI1787990, Length=333, Percent_Identity=32.7327327327327, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786226, Length=332, Percent_Identity=30.1204819277108, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI87082157, Length=242, Percent_Identity=28.9256198347107, Blast_Score=86, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17506929, Length=326, Percent_Identity=37.4233128834356, Blast_Score=177, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6325261, Length=232, Percent_Identity=38.7931034482759, Blast_Score=155, Evalue=6e-39,
Organism=Drosophila melanogaster, GI17136898, Length=319, Percent_Identity=35.423197492163, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24652801, Length=319, Percent_Identity=35.423197492163, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 36351; Mature: 36220

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYKDIWVFVEQREQKLMNVSLEILGEARRLADKKGVKACAVLVGYEVKGLAEELIKYG
CCCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCC
ADVVYVIDHPLLKNYTTDAYTKVICDLANSLKPEVILYGATYIGRDLAPRIAARMRTGLT
CCEEEEECCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHCCCC
ADCTALDIDENGLLLQIRPAFGGNLIATIICPERRPQMATIRPGVMKKALMDEGRRGEVI
CCCEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCCEECCHHHHHHHHHCCCCCCCEE
EIKPVIEEKDIRTEIISIIKEARQKVNLEEADIIVSGGRGVGGPEGFKLIEELAEVLGGV
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
VGASRAAVEAGWISSDHQVGQTGKTVRPKLYIACGISGAIQHIAGMGGAKTIVAINKNPD
HCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCC
APIFKIADYGIVGDLFKVIPALIEEIKEAKKKAMA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEYKDIWVFVEQREQKLMNVSLEILGEARRLADKKGVKACAVLVGYEVKGLAEELIKYG
CCCCHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHCC
ADVVYVIDHPLLKNYTTDAYTKVICDLANSLKPEVILYGATYIGRDLAPRIAARMRTGLT
CCEEEEECCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHCCCC
ADCTALDIDENGLLLQIRPAFGGNLIATIICPERRPQMATIRPGVMKKALMDEGRRGEVI
CCCEEEEECCCCEEEEEECCCCCCEEEEEECCCCCCCCEECCHHHHHHHHHCCCCCCCEE
EIKPVIEEKDIRTEIISIIKEARQKVNLEEADIIVSGGRGVGGPEGFKLIEELAEVLGGV
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
VGASRAAVEAGWISSDHQVGQTGKTVRPKLYIACGISGAIQHIAGMGGAKTIVAINKNPD
HCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCEEEEEEECCCC
APIFKIADYGIVGDLFKVIPALIEEIKEAKKKAMA
CCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA