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The map label for this gene is secA [H]

Identifier: 20807023

GI number: 20807023

Start: 528297

End: 531002

Strand: Direct

Name: secA [H]

Synonym: TTE0522

Alternate gene names: 20807023

Gene position: 528297-531002 (Clockwise)

Preceding gene: 20807022

Following gene: 20807024

Centisome position: 19.64

GC content: 40.76

Gene sequence:

>2706_bases
GTGATAAAAATGTTGGGCTTAGTTGAAAAAATATTTGGCAGTTACAGTGAAAGAGAAGTAAGGAGACTGGAGCCAATTGC
GGAGAAAGTTTTGTCATATGAAGACCAGATGGCAAGGCTTACTGATGCGGAGTTAAGGGCGAAGACAGATGAGTTTAAAA
ATAGATTGAAAAACGGTGAAACCCTTGATGATATACTTCCTGAAGCTTTTGCAGTTGTGAGAGAGGCTGCCTGGAGAACA
TTAAAGATGAAGCACTTCAAGGTACAGATAATAGGTGGCATTGTCCTTCACCAGGGGCGTATTGCCGAGATGAAGACTGG
TGAAGGTAAGACATTGGTGGCTACTCTGCCCGCATATCTTAATGCTTTGGAAGGAAAAGGAGTTCACATTGTAACTGTCA
ATGACTACTTGGCTAAAAGAGATAGAGATTGGATGGGGAAGATATACGAATTTTTGGGGTTAAGTGTGGGAGTAATACTT
CACGACATGGGACCTGCAGAGAGAAAGAAAGCCTATGCAGCTGATATAACCTATGGTACAAACAATGAATTTGGCTTTGA
CTACTTGAGAGACAACATGGTCATATACAAAGAAGATATGGTTCAAAGAGAGCTCAATTATGCCATAATAGACGAGGTAG
ACAGCATACTGATAGATGAAGCCAGAACTCCTCTCATAATCTCTGGAGTGGGCGAAAAATCCACAGATATGTACAAATTA
GCTGACAGGTTTGTAAGGACTTTGAAAAAAGATGAAGACTATGTAGTTGATGAGAAGGCGAAGGCTGTAAGTTTAACTGA
AAAAGGAGTTGCCAAGGCAGAGAAATTTTTTGGGATAAAAAATTTAGCAGATATTGAGAACATGGAGATTTCTCACCACA
TTCAGCAGGCATTGAAAGCTCATGCGATAATGAAGAGGGACAGAGATTATGTTGTAAAAGACGGTCAGGTCATAATAGTA
GATGAATTTACAGGAAGGCTCATGTTTGGAAGAAGATATAGCGAAGGTTTGCACCAGGCTATTGAGGCTAAAGAGGGAGT
AAAAGTTGAAAGGGAAAGTAAAACCCTTGCTACTATAACTTTACAAAATTATTTCAGGATGTACAAAAAATTAGCCGGTA
TGACAGGTACTGCTCAGACAGAAGAGCAGGAATTCAGAGACATATACGGATTGGATGTTGTAGTGATTCCCACTCACAAG
CCCATGATAAGAATAGACCACCCTGATGTAATATACAAAACAGAAGAGGCAAAATTCAGAGCAGTGGTTGAAGACATTGT
GGAAAGGCATAAAAAGGGTCAGCCTGTTCTTGTGGGTACTGTTTCTATTGAAAAATCTGAAAAATTAAGCGCAATGCTGA
AAAAAAGAGGAATACCCCATCAGGTTTTAAATGCCAAGTACCATGAAAAGGAAGCAGAGATAATAGCGCAGGCTGGTAGA
AAAGGAGCAGTCACAATTGCTACAAACATGGCAGGACGTGGTACAGATATTCTCTTAGGCGGAAATCCTGAGTTTATTGC
AAAGAGAAAAATGCTGGAGGAAGGCTATTCCAAAGAGATTATAAATGAGGCGGCAGGGTACGGTCCCGTGTCCAGTGAAG
AAGTGAGAAAAGCCCGCGAAAGGTATTTTGAGCTTTTGGAAGAAGCCAAGAAGGAGACGGAGAAAGAGCACGAAGAAGTC
GTAAAACTTGGCGGTTTGTACGTTATAGGTACAGAAAGGCATGAAGCGAGAAGAATTGACAATCAGTTGAGAGGCCGTGC
TGGCCGTCAGGGAGATCCGGGAGAATCAAGATTTTACATCTCTTTAGAAGACGACCTTATGAGGTTATTTGGTTCAGAGA
GGGTAAAAAACCTGATGGACAGTTTAGGGATTGATGATGACCAGCCAATAGAGCACAAAATTCTTACAAAGCAGATTGAG
CAGGCGCAGAAAAAAGTAGAAGGCATAAACTTTGACATAAGAAAGCATCTCCTCCAGTACGACGATGTTATGAACAAACA
AAGAGAAATCATATACGCTCAGAGGAGAAAGGTTTTGGAAGGGGAAAACCTCAAGGATTCTATCCTTGAGATGGTAAGAA
GCATAATAGAAAGATATGTAGAAATTTATACGGCAGGTAGCAAATATCCTGAAGAATGGGATATAAAGGGGCTTTTGGAT
CACTTATATGAGATGTTCCTTGAAAAAGACAGCGTTGTAATAGATGTGGATCTAGATAGGCTTGACAAAGAGGTTCTGAC
TGACATAATATATGAAGAGGCGGTAAGGCAGTACGAGAGAAAAGAAGCCGAAATTGGCCCTGAGCAGATGAGAGAAATTG
AAAGAATAGTATTACTGAGGGTTGTTGATACTAAGTGGATGGACCACATAGATGAAATGGACCAATTGCGCCAGGGCATA
GGATTGAGAGCTTACGGGCAGGTAGATCCTTTGATTGAGTATAAAAAGATAGCTTTTGACATGTTTGAGGATTTGATACA
CAGTATCCAAGAGGATACAGTCAAATTCTTATACAGGATTCAGGTGAACAAAGACAACAAGCTCAAGAGAGAGCAGGTTG
CAAAGCCAGTTTCTACTAATATAAACGGCGAAGGAGATAATAAAAAACAGCCTGTAGTGAAAGAGAAGAAAGTGGGCAGA
AATGACCCGTGCCCCTGTGGAAGCGGCAAGAAATACAAAAAATGCTGCGGAGCTAATGTAAAATAA

Upstream 100 bases:

>100_bases
TGTGAAGATAGTGTAAAATATTATTTAAAAGGGCTGTTTTTTATTGTCATCCACTTCCTGTAGTGATATAATATATACTT
GATTAACGATACCTTAGAAG

Downstream 100 bases:

>100_bases
AGGGAAAAGGAGAGGATGAGAATTGCTGCAGGATTACAGGGCAGAAGTTGAGCAAATGCTTCATGAGATAAAAGAAATGG
GTGTTTCTCTTTGACGTGGA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 901; Mature: 901

Protein sequence:

>901_residues
MIKMLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGETLDDILPEAFAVVREAAWRT
LKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVIL
HDMGPAERKKAYAADITYGTNNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKL
ADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKAHAIMKRDRDYVVKDGQVIIV
DEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATITLQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHK
PMIRIDHPDVIYKTEEAKFRAVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGR
KGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARERYFELLEEAKKETEKEHEEV
VKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYISLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIE
QAQKKVEGINFDIRKHLLQYDDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLD
HLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLRVVDTKWMDHIDEMDQLRQGI
GLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRIQVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGR
NDPCPCGSGKKYKKCCGANVK

Sequences:

>Translated_901_residues
MIKMLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGETLDDILPEAFAVVREAAWRT
LKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVIL
HDMGPAERKKAYAADITYGTNNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKL
ADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKAHAIMKRDRDYVVKDGQVIIV
DEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATITLQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHK
PMIRIDHPDVIYKTEEAKFRAVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGR
KGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARERYFELLEEAKKETEKEHEEV
VKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYISLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIE
QAQKKVEGINFDIRKHLLQYDDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLD
HLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLRVVDTKWMDHIDEMDQLRQGI
GLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRIQVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGR
NDPCPCGSGKKYKKCCGANVK
>Mature_901_residues
MIKMLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGETLDDILPEAFAVVREAAWRT
LKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYLNALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVIL
HDMGPAERKKAYAADITYGTNNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKL
ADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKAHAIMKRDRDYVVKDGQVIIV
DEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATITLQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHK
PMIRIDHPDVIYKTEEAKFRAVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGR
KGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARERYFELLEEAKKETEKEHEEV
VKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYISLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIE
QAQKKVEGINFDIRKHLLQYDDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLD
HLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLRVVDTKWMDHIDEMDQLRQGI
GLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRIQVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGR
NDPCPCGSGKKYKKCCGANVK

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family [H]

Homologues:

Organism=Escherichia coli, GI1786287, Length=935, Percent_Identity=49.3048128342246, Blast_Score=879, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116 [H]

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW [H]

EC number: NA

Molecular weight: Translated: 103458; Mature: 103458

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS01312 SECA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKMLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGE
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLDDILPEAFAVVREAAWRTLKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYL
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHEECCCEEEECCCCCCEEEEEHHHHH
NALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVILHDMGPAERKKAYAADITYGT
HHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHCCHHHHHEECCCCHHHHHHEEEEEEECC
NNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKL
CCCCCHHHHHCCEEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHH
ADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKA
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHH
HAIMKRDRDYVVKDGQVIIVDEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATIT
HHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEH
LQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHKPMIRIDHPDVIYKTEEAKFR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCEEEECCCCEEEECCHHHHH
AVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGR
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCC
KGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARE
CCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
RYFELLEEAKKETEKEHEEVVKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIEQAQKKVEGINFDIRKHLLQY
EEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLR
HHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVDTKWMDHIDEMDQLRQGIGLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRI
HHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
QVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGRNDPCPCGSGKKYKKCCGANV
EECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCCCC
K
C
>Mature Secondary Structure
MIKMLGLVEKIFGSYSEREVRRLEPIAEKVLSYEDQMARLTDAELRAKTDEFKNRLKNGE
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TLDDILPEAFAVVREAAWRTLKMKHFKVQIIGGIVLHQGRIAEMKTGEGKTLVATLPAYL
CHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHHHEECCCEEEECCCCCCEEEEEHHHHH
NALEGKGVHIVTVNDYLAKRDRDWMGKIYEFLGLSVGVILHDMGPAERKKAYAADITYGT
HHHCCCCEEEEEECHHHHHCCHHHHHHHHHHHCCHHHHHEECCCCHHHHHHEEEEEEECC
NNEFGFDYLRDNMVIYKEDMVQRELNYAIIDEVDSILIDEARTPLIISGVGEKSTDMYKL
CCCCCHHHHHCCEEEEHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHH
ADRFVRTLKKDEDYVVDEKAKAVSLTEKGVAKAEKFFGIKNLADIENMEISHHIQQALKA
HHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHH
HAIMKRDRDYVVKDGQVIIVDEFTGRLMFGRRYSEGLHQAIEAKEGVKVERESKTLATIT
HHHHHCCCCEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEH
LQNYFRMYKKLAGMTGTAQTEEQEFRDIYGLDVVVIPTHKPMIRIDHPDVIYKTEEAKFR
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEECCCCCEEEECCCCEEEECCHHHHH
AVVEDIVERHKKGQPVLVGTVSIEKSEKLSAMLKKRGIPHQVLNAKYHEKEAEIIAQAGR
HHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCC
KGAVTIATNMAGRGTDILLGGNPEFIAKRKMLEEGYSKEIINEAAGYGPVSSEEVRKARE
CCEEEEEECCCCCCCEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHH
RYFELLEEAKKETEKEHEEVVKLGGLYVIGTERHEARRIDNQLRGRAGRQGDPGESRFYI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEE
SLEDDLMRLFGSERVKNLMDSLGIDDDQPIEHKILTKQIEQAQKKVEGINFDIRKHLLQY
EEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
DDVMNKQREIIYAQRRKVLEGENLKDSILEMVRSIIERYVEIYTAGSKYPEEWDIKGLLD
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
HLYEMFLEKDSVVIDVDLDRLDKEVLTDIIYEEAVRQYERKEAEIGPEQMREIERIVLLR
HHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
VVDTKWMDHIDEMDQLRQGIGLRAYGQVDPLIEYKKIAFDMFEDLIHSIQEDTVKFLYRI
HHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEE
QVNKDNKLKREQVAKPVSTNINGEGDNKKQPVVKEKKVGRNDPCPCGSGKKYKKCCGANV
EECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]