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The map label for this gene is HflC [C]

Identifier: 20806896

GI number: 20806896

Start: 407007

End: 407786

Strand: Reverse

Name: HflC [C]

Synonym: TTE0384

Alternate gene names: 20806896

Gene position: 407786-407007 (Counterclockwise)

Preceding gene: 20806897

Following gene: 20806879

Centisome position: 15.16

GC content: 40.0

Gene sequence:

>780_bases
ATGAAAGTGATTGAAAGTCTAGCTTTTCTTTTTACTCTGGCAATCATACTGATAAGTCTAATTTCTGCATCCATTAGAAT
AGTGCAGGAGTATGAAAGAGGTGTAATTTTCCGTTTAGGACGCTACGTGGGAGTCAGAGGACCTGGAATATTCTTCTTAA
TTCCAATAATTGAAAGAATGCAAAAGGTCGACTTGAGAGTCGTTACAATGGAAGTTCCTACTCAAGAAGCAATTACTAAG
GATAACGTGACAATAAAAGTCAACGCCGTAGTATATTTCAGAGTGGTAGATCCTGCAAATGCAGTTATAAAGGTTTTAGA
CCATATAAGGGCAACATCCCAATTGGCACAGACCACCTTAAGAAGCGTACTGGGACAGTCTGATTTAGATGAGCTTTTGT
CTCACAGAGATGAGATAAATAAAAGGTTAAGAGAAATAATTGACGAAGGAACAGAGCCATGGGGAGTCAAAGTCAATTTA
GTTGAAATAAGAGATGTAGAATTGCCTCAGAGCATGCAAAGGGCCATGGCAGCACAGGCAGAAGCAGAAAGAGAACGCCG
AGCAAAAATAATAAGTGCTGACGGTGAATATCAAGCTGCAGCAAAACTTGCGGATGCTGCCAGAATAATTTCTTCTGAAC
CTGCTGCTCTCCAGCTAAGATACCTTCAAACCTTAAGAGAAATAGCTAACGACAGGTCAAATATTGTCATATTCCCATTT
TCACTGGACGTATTGCAGCAATTCTTCCCGCAAGCACAGAAGAAGGAAAAAGATGAGTAA

Upstream 100 bases:

>100_bases
CAGGCAGTCTCAAAAGAGCCTATTAAAAAGGGAGAGAAAGTTGTAATTATAGGAGTGGAAGGTCTTACTCTAAAAGTACA
AAAAGTAAAAGAGGGAGGTA

Downstream 100 bases:

>100_bases
ATTTTAAAAAAAGAACTGTCCCTTTAAATATTAGGGACAGTTCTTTCTTTTATTAGTCTCTCTAACTCCTCTACATTTCT
TGGCATCTTATTTCCTTTTA

Product: membrane protease subunit stomatin/prohibitin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKVIESLAFLFTLAIILISLISASIRIVQEYERGVIFRLGRYVGVRGPGIFFLIPIIERMQKVDLRVVTMEVPTQEAITK
DNVTIKVNAVVYFRVVDPANAVIKVLDHIRATSQLAQTTLRSVLGQSDLDELLSHRDEINKRLREIIDEGTEPWGVKVNL
VEIRDVELPQSMQRAMAAQAEAERERRAKIISADGEYQAAAKLADAARIISSEPAALQLRYLQTLREIANDRSNIVIFPF
SLDVLQQFFPQAQKKEKDE

Sequences:

>Translated_259_residues
MKVIESLAFLFTLAIILISLISASIRIVQEYERGVIFRLGRYVGVRGPGIFFLIPIIERMQKVDLRVVTMEVPTQEAITK
DNVTIKVNAVVYFRVVDPANAVIKVLDHIRATSQLAQTTLRSVLGQSDLDELLSHRDEINKRLREIIDEGTEPWGVKVNL
VEIRDVELPQSMQRAMAAQAEAERERRAKIISADGEYQAAAKLADAARIISSEPAALQLRYLQTLREIANDRSNIVIFPF
SLDVLQQFFPQAQKKEKDE
>Mature_259_residues
MKVIESLAFLFTLAIILISLISASIRIVQEYERGVIFRLGRYVGVRGPGIFFLIPIIERMQKVDLRVVTMEVPTQEAITK
DNVTIKVNAVVYFRVVDPANAVIKVLDHIRATSQLAQTTLRSVLGQSDLDELLSHRDEINKRLREIIDEGTEPWGVKVNL
VEIRDVELPQSMQRAMAAQAEAERERRAKIISADGEYQAAAKLADAARIISSEPAALQLRYLQTLREIANDRSNIVIFPF
SLDVLQQFFPQAQKKEKDE

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI38016911, Length=246, Percent_Identity=48.3739837398374, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI21686995, Length=246, Percent_Identity=44.3089430894309, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI221316744, Length=246, Percent_Identity=44.3089430894309, Blast_Score=203, Evalue=1e-52,
Organism=Homo sapiens, GI7657615, Length=252, Percent_Identity=37.3015873015873, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI7305503, Length=190, Percent_Identity=35.7894736842105, Blast_Score=133, Evalue=2e-31,
Organism=Homo sapiens, GI20149563, Length=161, Percent_Identity=36.6459627329193, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1786697, Length=194, Percent_Identity=38.1443298969072, Blast_Score=148, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI193209764, Length=259, Percent_Identity=49.034749034749, Blast_Score=239, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17569499, Length=256, Percent_Identity=51.953125, Blast_Score=239, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17569493, Length=243, Percent_Identity=50.6172839506173, Blast_Score=238, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI25153583, Length=251, Percent_Identity=50.996015936255, Blast_Score=234, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI71987612, Length=257, Percent_Identity=50.1945525291829, Blast_Score=234, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI71987621, Length=257, Percent_Identity=50.1945525291829, Blast_Score=233, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17570459, Length=243, Percent_Identity=48.559670781893, Blast_Score=231, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17570161, Length=252, Percent_Identity=46.4285714285714, Blast_Score=211, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI193210507, Length=252, Percent_Identity=46.4285714285714, Blast_Score=211, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI17569497, Length=246, Percent_Identity=43.4959349593496, Blast_Score=207, Evalue=4e-54,
Organism=Caenorhabditis elegans, GI71989948, Length=234, Percent_Identity=47.4358974358974, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI32566490, Length=231, Percent_Identity=52.3809523809524, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71989955, Length=179, Percent_Identity=51.9553072625698, Blast_Score=168, Evalue=3e-42,
Organism=Caenorhabditis elegans, GI32564147, Length=196, Percent_Identity=38.265306122449, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71989963, Length=118, Percent_Identity=51.6949152542373, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17542664, Length=168, Percent_Identity=30.952380952381, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45556022, Length=254, Percent_Identity=48.0314960629921, Blast_Score=230, Evalue=8e-61,
Organism=Drosophila melanogaster, GI18860517, Length=251, Percent_Identity=49.402390438247, Blast_Score=229, Evalue=1e-60,
Organism=Drosophila melanogaster, GI62484448, Length=248, Percent_Identity=46.3709677419355, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24657857, Length=248, Percent_Identity=46.3709677419355, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI62484274, Length=248, Percent_Identity=46.3709677419355, Blast_Score=206, Evalue=1e-53,
Organism=Drosophila melanogaster, GI281365664, Length=248, Percent_Identity=46.3709677419355, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI28573263, Length=247, Percent_Identity=41.7004048582996, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI21356845, Length=250, Percent_Identity=39.6, Blast_Score=194, Evalue=7e-50,
Organism=Drosophila melanogaster, GI281361633, Length=246, Percent_Identity=39.0243902439024, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281361631, Length=246, Percent_Identity=39.0243902439024, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI281361635, Length=185, Percent_Identity=39.4594594594595, Blast_Score=143, Evalue=9e-35,
Organism=Drosophila melanogaster, GI45550506, Length=197, Percent_Identity=36.5482233502538, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 29297; Mature: 29297

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIESLAFLFTLAIILISLISASIRIVQEYERGVIFRLGRYVGVRGPGIFFLIPIIERM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QKVDLRVVTMEVPTQEAITKDNVTIKVNAVVYFRVVDPANAVIKVLDHIRATSQLAQTTL
HHCCEEEEEEECCCHHHHCCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RSVLGQSDLDELLSHRDEINKRLREIIDEGTEPWGVKVNLVEIRDVELPQSMQRAMAAQA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHH
EAERERRAKIISADGEYQAAAKLADAARIISSEPAALQLRYLQTLREIANDRSNIVIFPF
HHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
SLDVLQQFFPQAQKKEKDE
CHHHHHHHHCHHHHCCCCC
>Mature Secondary Structure
MKVIESLAFLFTLAIILISLISASIRIVQEYERGVIFRLGRYVGVRGPGIFFLIPIIERM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QKVDLRVVTMEVPTQEAITKDNVTIKVNAVVYFRVVDPANAVIKVLDHIRATSQLAQTTL
HHCCEEEEEEECCCHHHHCCCCEEEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
RSVLGQSDLDELLSHRDEINKRLREIIDEGTEPWGVKVNLVEIRDVELPQSMQRAMAAQA
HHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHH
EAERERRAKIISADGEYQAAAKLADAARIISSEPAALQLRYLQTLREIANDRSNIVIFPF
HHHHHHHHHEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEC
SLDVLQQFFPQAQKKEKDE
CHHHHHHHHCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]