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The map label for this gene is Fur2 [H]

Identifier: 20806879

GI number: 20806879

Start: 391132

End: 391548

Strand: Reverse

Name: Fur2 [H]

Synonym: TTE0366

Alternate gene names: 20806879

Gene position: 391548-391132 (Counterclockwise)

Preceding gene: 20806896

Following gene: 20806878

Centisome position: 14.56

GC content: 35.49

Gene sequence:

>417_bases
GTGCAGAAAGAGGAAGCTTTAAAAAAATTAAAAGCACATAATTACAAGCTTACGCCTCAGAGAGAATTAATACTTGACAT
AATGCTTTCCAACCAGGGCTATTTGTCTGTAAAAGATGTGTACGAAAAAGTAAGAGAAGTCTTCCCTCAGGTGAGCATTG
ACACTGTGTACAGGACTTTAAGCCTTTTAAAGAACTTGAATATTTTAAATGAGGCGATAATTGGAAATAATATTATGTAC
GTGGCAAAAAAACACCTGCACAATCACACAATGAGGTGTTTAAAATGCGGCAGAGTATTTGAAATGGAAATATGCCCTCT
TGAGCTTTTGATAGACCAGATAAAGGATTTTGAAGTCGTAGACCACAAAATAGAAATTGTAGGATACTGTAAAGAATGCA
GGTCAAATCCAAACTGA

Upstream 100 bases:

>100_bases
CTGAAATTTCAATAAGAATCTGGATATTGACATACCTTTTAAATCGTAATATAATCTTAATTAAGAAAATTTTCTTATTT
AATAAAAGGTTGTGATTAAA

Downstream 100 bases:

>100_bases
GAAATGGAGGCTTTCAAATATGAAAAAACTAGTAATGGCTTTAGTCTTAGCTTCAATGATTTTTACACTGGTTTCTTGCA
GCACCACTGCTAATTCATCT

Product: Fe2+/Zn2+ uptake regulation proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MQKEEALKKLKAHNYKLTPQRELILDIMLSNQGYLSVKDVYEKVREVFPQVSIDTVYRTLSLLKNLNILNEAIIGNNIMY
VAKKHLHNHTMRCLKCGRVFEMEICPLELLIDQIKDFEVVDHKIEIVGYCKECRSNPN

Sequences:

>Translated_138_residues
MQKEEALKKLKAHNYKLTPQRELILDIMLSNQGYLSVKDVYEKVREVFPQVSIDTVYRTLSLLKNLNILNEAIIGNNIMY
VAKKHLHNHTMRCLKCGRVFEMEICPLELLIDQIKDFEVVDHKIEIVGYCKECRSNPN
>Mature_138_residues
MQKEEALKKLKAHNYKLTPQRELILDIMLSNQGYLSVKDVYEKVREVFPQVSIDTVYRTLSLLKNLNILNEAIIGNNIMY
VAKKHLHNHTMRCLKCGRVFEMEICPLELLIDQIKDFEVVDHKIEIVGYCKECRSNPN

Specific function: Required for the zinc-specific repression of two operons implicated in zinc uptake, yciC and ycdHIyceA. Also represses the expression of rpmE2, the gene for ribosomal protein L31B, which is expressed only after the end of exponential growth [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16162; Mature: 16162

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEEALKKLKAHNYKLTPQRELILDIMLSNQGYLSVKDVYEKVREVFPQVSIDTVYRTL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHH
SLLKNLNILNEAIIGNNIMYVAKKHLHNHTMRCLKCGRVFEMEICPLELLIDQIKDFEVV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCHHHH
DHKIEIVGYCKECRSNPN
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQKEEALKKLKAHNYKLTPQRELILDIMLSNQGYLSVKDVYEKVREVFPQVSIDTVYRTL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCHHHHHHHH
SLLKNLNILNEAIIGNNIMYVAKKHLHNHTMRCLKCGRVFEMEICPLELLIDQIKDFEVV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHCHHHH
DHKIEIVGYCKECRSNPN
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 9811636 [H]