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The map label for this gene is PitA [H]

Identifier: 20806846

GI number: 20806846

Start: 346859

End: 347857

Strand: Direct

Name: PitA [H]

Synonym: TTE0329

Alternate gene names: 20806846

Gene position: 346859-347857 (Clockwise)

Preceding gene: 20806844

Following gene: 20806847

Centisome position: 12.9

GC content: 34.93

Gene sequence:

>999_bases
ATGGCTCTTTACACGCTTACAATTGCAGTAATATTTTTATACATCTTTATTACAGGCTTTCATGACGAGGGAAATTTAAT
AGCTACCATCGTATGTTCAAGGTCTATAGAGGCGAAAAAAGCTTTAATTATAGCTTCTGTTGCTCAGTTTTTAGGACCTT
TGATTGTTACCACGGCAGTTAGCACTACTATTGCAAAGGATATTATAAAATATTCTTACCTTCTTAACAGCGGTGAAAAT
ATATCATTGTTGATACTTTCTGGTATCTTGGGAGCTGCTTTGTGGAATTTTATAACATGGTACTATGCTATTCCTTCTAG
CTCTTCGCATGCTTTAATTGGAGGTATATTGGGGCCTTTTGCAATAGAGTACGGTTTTCATTCTATCAATTTTTACGGAA
TAATGACAAAAGTTATAATACCTCTATTTTTTTCTCCTGTAATAGGCTTTGCTGCTGGATATATAATTACATTAATTTTC
TGGAAATTATTGAAAAATGCGCAACCTTCTGTGAATAGTTTTCTTAAAAAACTTCAATACGGTACGATGTTTTTATTGAA
TATAGGGCAAAGTGCAAACGATGCTCAAAAAGGAATGGGTTTGATTGTAATTTTAATGATGATAAAGGGAAACACTCATA
ATTTTGAAGTTCCCTTTTTTATAAAATATATAGCAGCTTTTATGATATCCTTTGGTCTTTTATTTGGTGGATTTAGAATG
ATAAAAAGTGTGGGCGGAAGGATATACAGAGTAAGACCTTTTCACTCTTTTAATGCTCAGCTTTCATCTCTTTTGGTAGT
GACTGCTGCTACTTTGGTTGGAGCGCCTATAAGTGGCACACAGCTTGTGAACTCTTCCATTTTGGGCGTTGGAGCAAGGG
AGAGGCCTAGCGCAGTAAGATGGCAGTTTGCAAAAGCCATATTTGCCGCCTGGATTACCACAATACCAGCTTCTTTTATA
TTTTCTTCCATCATTTATATGGTTGCTAAATTATTGTAA

Upstream 100 bases:

>100_bases
AACAGATGAGATATTGAAGAAAATCTGGGATACAGTTATAATTGTAATATAATTAAAAACCTCAAATCTGTTATAATACT
AAAGACTTGAGGTGAAAAAT

Downstream 100 bases:

>100_bases
GAGGTGATGAAGGTGAATGTATTTAAATGGCTTTTTACTGAAAGTGTTGATTTCTACAAACTGTTGCAGGAGCAGTCTAA
ACTTACACTGCAGGGAGTAA

Product: phosphate/sulphate permeases

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MALYTLTIAVIFLYIFITGFHDEGNLIATIVCSRSIEAKKALIIASVAQFLGPLIVTTAVSTTIAKDIIKYSYLLNSGEN
ISLLILSGILGAALWNFITWYYAIPSSSSHALIGGILGPFAIEYGFHSINFYGIMTKVIIPLFFSPVIGFAAGYIITLIF
WKLLKNAQPSVNSFLKKLQYGTMFLLNIGQSANDAQKGMGLIVILMMIKGNTHNFEVPFFIKYIAAFMISFGLLFGGFRM
IKSVGGRIYRVRPFHSFNAQLSSLLVVTAATLVGAPISGTQLVNSSILGVGARERPSAVRWQFAKAIFAAWITTIPASFI
FSSIIYMVAKLL

Sequences:

>Translated_332_residues
MALYTLTIAVIFLYIFITGFHDEGNLIATIVCSRSIEAKKALIIASVAQFLGPLIVTTAVSTTIAKDIIKYSYLLNSGEN
ISLLILSGILGAALWNFITWYYAIPSSSSHALIGGILGPFAIEYGFHSINFYGIMTKVIIPLFFSPVIGFAAGYIITLIF
WKLLKNAQPSVNSFLKKLQYGTMFLLNIGQSANDAQKGMGLIVILMMIKGNTHNFEVPFFIKYIAAFMISFGLLFGGFRM
IKSVGGRIYRVRPFHSFNAQLSSLLVVTAATLVGAPISGTQLVNSSILGVGARERPSAVRWQFAKAIFAAWITTIPASFI
FSSIIYMVAKLL
>Mature_331_residues
ALYTLTIAVIFLYIFITGFHDEGNLIATIVCSRSIEAKKALIIASVAQFLGPLIVTTAVSTTIAKDIIKYSYLLNSGENI
SLLILSGILGAALWNFITWYYAIPSSSSHALIGGILGPFAIEYGFHSINFYGIMTKVIIPLFFSPVIGFAAGYIITLIFW
KLLKNAQPSVNSFLKKLQYGTMFLLNIGQSANDAQKGMGLIVILMMIKGNTHNFEVPFFIKYIAAFMISFGLLFGGFRMI
KSVGGRIYRVRPFHSFNAQLSSLLVVTAATLVGAPISGTQLVNSSILGVGARERPSAVRWQFAKAIFAAWITTIPASFIF
SSIIYMVAKLL

Specific function: Low-affinity inorganic phosphate transport (Probable) [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Homo sapiens, GI5803173, Length=151, Percent_Identity=28.476821192053, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI31543630, Length=164, Percent_Identity=28.0487804878049, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1789907, Length=218, Percent_Identity=33.0275229357798, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1789360, Length=220, Percent_Identity=30, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17539280, Length=175, Percent_Identity=25.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25146401, Length=169, Percent_Identity=24.2603550295858, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 36277; Mature: 36145

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALYTLTIAVIFLYIFITGFHDEGNLIATIVCSRSIEAKKALIIASVAQFLGPLIVTTAV
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
STTIAKDIIKYSYLLNSGENISLLILSGILGAALWNFITWYYAIPSSSSHALIGGILGPF
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AIEYGFHSINFYGIMTKVIIPLFFSPVIGFAAGYIITLIFWKLLKNAQPSVNSFLKKLQY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GTMFLLNIGQSANDAQKGMGLIVILMMIKGNTHNFEVPFFIKYIAAFMISFGLLFGGFRM
CCEEEEECCCCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKSVGGRIYRVRPFHSFNAQLSSLLVVTAATLVGAPISGTQLVNSSILGVGARERPSAVR
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCCCHHHH
WQFAKAIFAAWITTIPASFIFSSIIYMVAKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ALYTLTIAVIFLYIFITGFHDEGNLIATIVCSRSIEAKKALIIASVAQFLGPLIVTTAV
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
STTIAKDIIKYSYLLNSGENISLLILSGILGAALWNFITWYYAIPSSSSHALIGGILGPF
HHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
AIEYGFHSINFYGIMTKVIIPLFFSPVIGFAAGYIITLIFWKLLKNAQPSVNSFLKKLQY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
GTMFLLNIGQSANDAQKGMGLIVILMMIKGNTHNFEVPFFIKYIAAFMISFGLLFGGFRM
CCEEEEECCCCCCHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IKSVGGRIYRVRPFHSFNAQLSSLLVVTAATLVGAPISGTQLVNSSILGVGARERPSAVR
HHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCCCHHHH
WQFAKAIFAAWITTIPASFIFSSIIYMVAKLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9696772; 11481430 [H]