Click here to switch to the map view.

The map label for this gene is yugK [H]

Identifier: 20806830

GI number: 20806830

Start: 327970

End: 329142

Strand: Direct

Name: yugK [H]

Synonym: TTE0313

Alternate gene names: 20806830

Gene position: 327970-329142 (Clockwise)

Preceding gene: 20806829

Following gene: 20806831

Centisome position: 12.19

GC content: 39.39

Gene sequence:

>1173_bases
ATGAAAGACTTTATTTTTTCAAGTCCTACAAAGATTATCTTTGGAAAAGGGACAGAAGAGCAAGTTGGGAAAGAAGTAAA
AAATTATAGCAACAAAGTATTGTTATGCTATGGTGGAGGAAGCATAAAGAAATACGGATTGTACGATAAAGTCGTAAAGG
CTTTAAAAGAAGAGGGAGTTGAATTTGTAGAGCTATCAGGGGTAAAGCCTAATCCTAGACTTGGCCTTGTACAGGAAGGG
ATAAAATTAGTTAGAGAAAACAATATCAACTTTATTTTAGCTGTTGGCGGGGGAAGTGTTATTGACACTGCAAAGGCTAT
CGCAATGGGAGTGCCTTATGAAGGGAATGTTTGGGACTTTTTTGAAGGAAAAGCAGAATTGAAAGAAGCTCTTCCTGTGG
GAGTGATTCTTACCATTCCAGCAACAGGCAGTGAGGCAAGTGATGCTACAGTTATCACAAATGAAGATGGGTGGTATAAG
ATAGGTTTCCACCATGAACTTTTGAGGCCTAAGTTTGCAATTATGAACCCAGAGCTTACATACACTCTTCCGCCGTATCA
GACTGCCTGTGGTGTTGCTGACATTATGGCACATATAATGGAGAGGTATTTTGTGAATGAAGAAGGAGTTGAGCTGACTG
ATAGACTCTGCGAGGCTACATTAAAGACTGTGATAAATAATGCCCGCATTGTTTTAAAAGACCCTGCTAATTACAATGCG
AGGGCGCAGATTATGTGGGCCGGCACAATTGCTCACAATGACCTTCTTAACACTGGAAGAGGAAGAGGAGATTGGGCATC
ACATAGAATTGAGCATGAACTAAGCGCTATTTACGACATTGCTCATGGAGCAGGCCTTGCTATTGTATTTCCTGCATGGA
TGAAGTATGTTTATAAAAATAACATTAATAGATTTGTTCAGTTTGCTGTAAAAGTTTGGGACGTTGATTTGCCGTACGAA
AACTTAGAAGAAATTGCCCTGGAAGGGATTAGAAGAACAGAAGAATTTTTTAAAGAGATTGGACTTCCAGTTAGATTGAA
AGAGGCAGGCATTTCGGACGATAGGTTTGAAGAGATGGCTGACAAGTGTACAAAGGGAGGAACCAGGACAATAGGAGATT
TTGTTAAACTTAATAAAGAAGATATAATAAAAATTTACGAGTTGGCGAGGTAA

Upstream 100 bases:

>100_bases
TATTTGAAAAAGGTAAAAAGAGCTCAAATTTAGTGAAAAAATGAGATTTTTCAAGCTTGATTGAGCTAATTACAAAATAT
TGAGATAGGGAGTGGTCTTG

Downstream 100 bases:

>100_bases
AAGTCAGTATTTTTAGCTGACTTTTCTTTTTTGTTACAATTTGGACATAAAAAAGTGATATAATTTATGATATAATCAAT
ATGATTGGATAAACCATAAT

Product: oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKDFIFSSPTKIIFGKGTEEQVGKEVKNYSNKVLLCYGGGSIKKYGLYDKVVKALKEEGVEFVELSGVKPNPRLGLVQEG
IKLVRENNINFILAVGGGSVIDTAKAIAMGVPYEGNVWDFFEGKAELKEALPVGVILTIPATGSEASDATVITNEDGWYK
IGFHHELLRPKFAIMNPELTYTLPPYQTACGVADIMAHIMERYFVNEEGVELTDRLCEATLKTVINNARIVLKDPANYNA
RAQIMWAGTIAHNDLLNTGRGRGDWASHRIEHELSAIYDIAHGAGLAIVFPAWMKYVYKNNINRFVQFAVKVWDVDLPYE
NLEEIALEGIRRTEEFFKEIGLPVRLKEAGISDDRFEEMADKCTKGGTRTIGDFVKLNKEDIIKIYELAR

Sequences:

>Translated_390_residues
MKDFIFSSPTKIIFGKGTEEQVGKEVKNYSNKVLLCYGGGSIKKYGLYDKVVKALKEEGVEFVELSGVKPNPRLGLVQEG
IKLVRENNINFILAVGGGSVIDTAKAIAMGVPYEGNVWDFFEGKAELKEALPVGVILTIPATGSEASDATVITNEDGWYK
IGFHHELLRPKFAIMNPELTYTLPPYQTACGVADIMAHIMERYFVNEEGVELTDRLCEATLKTVINNARIVLKDPANYNA
RAQIMWAGTIAHNDLLNTGRGRGDWASHRIEHELSAIYDIAHGAGLAIVFPAWMKYVYKNNINRFVQFAVKVWDVDLPYE
NLEEIALEGIRRTEEFFKEIGLPVRLKEAGISDDRFEEMADKCTKGGTRTIGDFVKLNKEDIIKIYELAR
>Mature_390_residues
MKDFIFSSPTKIIFGKGTEEQVGKEVKNYSNKVLLCYGGGSIKKYGLYDKVVKALKEEGVEFVELSGVKPNPRLGLVQEG
IKLVRENNINFILAVGGGSVIDTAKAIAMGVPYEGNVWDFFEGKAELKEALPVGVILTIPATGSEASDATVITNEDGWYK
IGFHHELLRPKFAIMNPELTYTLPPYQTACGVADIMAHIMERYFVNEEGVELTDRLCEATLKTVINNARIVLKDPANYNA
RAQIMWAGTIAHNDLLNTGRGRGDWASHRIEHELSAIYDIAHGAGLAIVFPAWMKYVYKNNINRFVQFAVKVWDVDLPYE
NLEEIALEGIRRTEEFFKEIGLPVRLKEAGISDDRFEEMADKCTKGGTRTIGDFVKLNKEDIIKIYELAR

Specific function: Unknown

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789386, Length=393, Percent_Identity=36.8956743002545, Blast_Score=268, Evalue=4e-73,
Organism=Escherichia coli, GI48994951, Length=389, Percent_Identity=24.9357326478149, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789163, Length=386, Percent_Identity=25.1295336787565, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87082107, Length=392, Percent_Identity=23.2142857142857, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787493, Length=408, Percent_Identity=26.2254901960784, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=408, Percent_Identity=21.8137254901961, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321181, Length=385, Percent_Identity=27.012987012987, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43606; Mature: 43606

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDFIFSSPTKIIFGKGTEEQVGKEVKNYSNKVLLCYGGGSIKKYGLYDKVVKALKEEGV
CCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
EFVELSGVKPNPRLGLVQEGIKLVRENNINFILAVGGGSVIDTAKAIAMGVPYEGNVWDF
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEHH
FEGKAELKEALPVGVILTIPATGSEASDATVITNEDGWYKIGFHHELLRPKFAIMNPELT
HCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEECCCHHHHCCEEEEECCCEE
YTLPPYQTACGVADIMAHIMERYFVNEEGVELTDRLCEATLKTVINNARIVLKDPANYNA
EECCCHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
RAQIMWAGTIAHNDLLNTGRGRGDWASHRIEHELSAIYDIAHGAGLAIVFPAWMKYVYKN
EEEEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
NINRFVQFAVKVWDVDLPYENLEEIALEGIRRTEEFFKEIGLPVRLKEAGISDDRFEEMA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
DKCTKGGTRTIGDFVKLNKEDIIKIYELAR
HHHHCCCCCHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure
MKDFIFSSPTKIIFGKGTEEQVGKEVKNYSNKVLLCYGGGSIKKYGLYDKVVKALKEEGV
CCCCCCCCCCEEEEECCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCC
EFVELSGVKPNPRLGLVQEGIKLVRENNINFILAVGGGSVIDTAKAIAMGVPYEGNVWDF
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCEEHH
FEGKAELKEALPVGVILTIPATGSEASDATVITNEDGWYKIGFHHELLRPKFAIMNPELT
HCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCEEEECCCHHHHCCEEEEECCCEE
YTLPPYQTACGVADIMAHIMERYFVNEEGVELTDRLCEATLKTVINNARIVLKDPANYNA
EECCCHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
RAQIMWAGTIAHNDLLNTGRGRGDWASHRIEHELSAIYDIAHGAGLAIVFPAWMKYVYKN
EEEEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHH
NINRFVQFAVKVWDVDLPYENLEEIALEGIRRTEEFFKEIGLPVRLKEAGISDDRFEEMA
HHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
DKCTKGGTRTIGDFVKLNKEDIIKIYELAR
HHHHCCCCCHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]