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The map label for this gene is AraH [H]

Identifier: 20806731

GI number: 20806731

Start: 211364

End: 212320

Strand: Direct

Name: AraH [H]

Synonym: TTE0205

Alternate gene names: 20806731

Gene position: 211364-212320 (Clockwise)

Preceding gene: 20806730

Following gene: 20806732

Centisome position: 7.86

GC content: 35.11

Gene sequence:

>957_bases
TTGAAGCTACCGAACGAAAAAGCAATGAAAATAAATATTGGTGAGTTGCTTTTAAAAGCGAAATCTTTAATAGGTTTATT
GGGATTAATTATCGCGTTTTCAATATTATCTCCACGTTTTTTGGATTACTATAACCTTACAAATGTATTAAGACAAACCT
CTCTAAATGCAATAATGGCTGTAGGGATGACATTTGTGATATTGACAGGTGGGATAGACCTATCTGTGGGTTCTATATTG
GCGTTTTCAAGTGCAGTTACAGCCGGTATGTTGAAAGATGGTATGCCCCTAATCATAGCTTTATTGGCGGGATTGATAAT
AGGTACTGGTTTAGGATTGTTTAATGGTTTTGTTATAATCAGGTGGAATATTCCTCCATTTATTGCTACATTTGCTATGA
TGACAATAGCAAGAGGGCTTACGCTTGTGTATACTAATGGCCAACCAATAACTGGCTTAGGAAAAGCTTTCGGATATATC
GGCAATGGGTATGTTGGTTCCATTCCTGTTCCAATAATTATCACAATTCTCGTTTTTGTAATAGGATACTATATTTTAAA
AAACAACAGATTAGGAAGATATGTATATGCAACCGGAGGAAATTTACAAGCTGCTAAACTGGCAGGAATTAATACTAATA
AAATAATTCTATTTGTATATGCTTTAAGTGGTTTTTTAGCAGCAGTAAGTGGCTTAATAATTACTTCAAGATTAAACTCA
GCTGCCCCAACAGCTGGACAAGGTGCAGAGCTTGATGCAATAGCTGCTGTTGTACTAGGAGGTACAAGTTTATCTGGGGG
CGAAGGTGGAATAATTGGGACTTTGATAGGTGCTTTAATAATAGGTGTGTTGAACAATGGTCTGAATTTGCTTAACGTTT
CACCTTTTTATCAATATATTGTAAAAGGTGTAGTAATATTACTTGCTATAGCTTTAGACAAAAAAGAAAGTGAGTAA

Upstream 100 bases:

>100_bases
AGAATTATAGTAATGCATGAAGGGAAAATAACAGGAGAAATTTCTCGCGAAGAAGCTACAGAAGAAAAAGTTATGTTAAA
AGCTGTAGGAGGGGAATAAA

Downstream 100 bases:

>100_bases
ATGAGAAAAGGGGGGATGTTTGGAAATTTAGAGTTTTTATTAGAGTTTTGGATAGTTTATATTAAAAAATTAAAGGGGTG
GAGAGATTTATGAGAAAATC

Product: ribose/xylose/arabinose/galactoside ABC-type transporter permease

Products: ADP; phosphate; ribose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKLPNEKAMKINIGELLLKAKSLIGLLGLIIAFSILSPRFLDYYNLTNVLRQTSLNAIMAVGMTFVILTGGIDLSVGSIL
AFSSAVTAGMLKDGMPLIIALLAGLIIGTGLGLFNGFVIIRWNIPPFIATFAMMTIARGLTLVYTNGQPITGLGKAFGYI
GNGYVGSIPVPIIITILVFVIGYYILKNNRLGRYVYATGGNLQAAKLAGINTNKIILFVYALSGFLAAVSGLIITSRLNS
AAPTAGQGAELDAIAAVVLGGTSLSGGEGGIIGTLIGALIIGVLNNGLNLLNVSPFYQYIVKGVVILLAIALDKKESE

Sequences:

>Translated_318_residues
MKLPNEKAMKINIGELLLKAKSLIGLLGLIIAFSILSPRFLDYYNLTNVLRQTSLNAIMAVGMTFVILTGGIDLSVGSIL
AFSSAVTAGMLKDGMPLIIALLAGLIIGTGLGLFNGFVIIRWNIPPFIATFAMMTIARGLTLVYTNGQPITGLGKAFGYI
GNGYVGSIPVPIIITILVFVIGYYILKNNRLGRYVYATGGNLQAAKLAGINTNKIILFVYALSGFLAAVSGLIITSRLNS
AAPTAGQGAELDAIAAVVLGGTSLSGGEGGIIGTLIGALIIGVLNNGLNLLNVSPFYQYIVKGVVILLAIALDKKESE
>Mature_318_residues
MKLPNEKAMKINIGELLLKAKSLIGLLGLIIAFSILSPRFLDYYNLTNVLRQTSLNAIMAVGMTFVILTGGIDLSVGSIL
AFSSAVTAGMLKDGMPLIIALLAGLIIGTGLGLFNGFVIIRWNIPPFIATFAMMTIARGLTLVYTNGQPITGLGKAFGYI
GNGYVGSIPVPIIITILVFVIGYYILKNNRLGRYVYATGGNLQAAKLAGINTNKIILFVYALSGFLAAVSGLIITSRLNS
AAPTAGQGAELDAIAAVVLGGTSLSGGEGGIIGTLIGALIIGVLNNGLNLLNVSPFYQYIVKGVVILLAIALDKKESE

Specific function: Part of the binding-protein-dependent transport system for ribose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790191, Length=305, Percent_Identity=54.7540983606557, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1788896, Length=326, Percent_Identity=37.1165644171779, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1790524, Length=297, Percent_Identity=41.4141414141414, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI145693152, Length=290, Percent_Identity=36.8965517241379, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI145693214, Length=249, Percent_Identity=40.1606425702811, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082395, Length=286, Percent_Identity=37.4125874125874, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1789992, Length=139, Percent_Identity=48.2014388489209, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788471, Length=297, Percent_Identity=37.037037037037, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787793, Length=280, Percent_Identity=32.5, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1787794, Length=292, Percent_Identity=32.1917808219178, Blast_Score=104, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 33181; Mature: 33181

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPNEKAMKINIGELLLKAKSLIGLLGLIIAFSILSPRFLDYYNLTNVLRQTSLNAIMA
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VGMTFVILTGGIDLSVGSILAFSSAVTAGMLKDGMPLIIALLAGLIIGTGLGLFNGFVII
HHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEE
RWNIPPFIATFAMMTIARGLTLVYTNGQPITGLGKAFGYIGNGYVGSIPVPIIITILVFV
EECCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IGYYILKNNRLGRYVYATGGNLQAAKLAGINTNKIILFVYALSGFLAAVSGLIITSRLNS
HHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCC
AAPTAGQGAELDAIAAVVLGGTSLSGGEGGIIGTLIGALIIGVLNNGLNLLNVSPFYQYI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHH
VKGVVILLAIALDKKESE
HHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLPNEKAMKINIGELLLKAKSLIGLLGLIIAFSILSPRFLDYYNLTNVLRQTSLNAIMA
CCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VGMTFVILTGGIDLSVGSILAFSSAVTAGMLKDGMPLIIALLAGLIIGTGLGLFNGFVII
HHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEE
RWNIPPFIATFAMMTIARGLTLVYTNGQPITGLGKAFGYIGNGYVGSIPVPIIITILVFV
EECCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
IGYYILKNNRLGRYVYATGGNLQAAKLAGINTNKIILFVYALSGFLAAVSGLIITSRLNS
HHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCHHEEHHHHHHHHHHHHHHHHHHHHCCC
AAPTAGQGAELDAIAAVVLGGTSLSGGEGGIIGTLIGALIIGVLNNGLNLLNVSPFYQYI
CCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHH
VKGVVILLAIALDKKESE
HHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ribose [Periplasm]; H2O [C]

Specific reaction: ATP + ribose [Periplasm] + H2O = ADP + phosphate + ribose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]