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The map label for this gene is Sua5 [H]

Identifier: 20806674

GI number: 20806674

Start: 143690

End: 144757

Strand: Direct

Name: Sua5 [H]

Synonym: TTE0145

Alternate gene names: 20806674

Gene position: 143690-144757 (Clockwise)

Preceding gene: 20806673

Following gene: 20806675

Centisome position: 5.34

GC content: 41.1

Gene sequence:

>1068_bases
TTGATGACAAAGGTAATAAAAATTGACAAAGATAATCCCGAAATTGAGCTTATAGATTACGCTGCAGAGGTTATAAAAAA
AGGAGGGCTTGTGGCTTTTCCCACAGAGACAGTCTACGGGATAGGTGCAAATTCTTTTGACGAAGAAGCTGTAAAAAGGA
TTTTTATTGCAAAGGGAAGGCCCCAGGACAATCCTTTGATTTTACACATAGCTTTGATGGATCAGGTTTATGAACTGGCG
GCAGAGTTTCCTGAAAAGGCCAAAAAGCTTGCTCATAGATTCTGGCCAGGTCCTCTTACTGTCGTTTTAAAAAAATCTGA
TAAAGTACCGTATGTAAACACTGCTGGCATGAATACTGTTGCCATAAGAATGCCTTCAAATCCAATAGCTCATCTTCTCA
TAAAGAGGGCAGGAGTCCCCATATCTGCTCCCAGCGCCAATGTGTCTGGAAAGCCTAGTCCTACAGATGCTTCTCACGTC
ATTGAGGACCTTTACGGCAAAGTGGACGTCATAATAGATGGAGGAAAGTGTGACGTGGGGTTGGAATCGACTGTGGTGGA
CCTTACTGAGGAAGTACCGGTTATTTTAAGGCCTGGGGCAGTTACTTTAGAGATGTTAAAAGAGGTATTGGGGGAAGTAA
AATTAGACCCTTCTCTTTTGACAAGGCCGGATGAGAATATAAAGCCTAAATCTCCCGGAATGAAGTACAAGCATTATTCT
CCCAAGGCTGAAGTTTACATTGTAAAAGGACCTCTTGATAAAGTTGTAAAAAAGATTCAGCAATTGGCAAAAAATCAATT
GAAAAATGGCAAAAAAGTTGGTATAATGGCGACAGTGCAAACTTCGACACAATATAAAGAGGGAGAGATAATTGTCGTCG
GTGATAGAGACAAACCAGAGACCATTGCGAAAAATTTGTTTGAGACTTTACGAGAGTTCGACAGAAGAGGAGTAGAAGTG
GTATTTGCTGAAAGCTTCAATTATGATGACATTGGACTTGCCATAATGAACAGGTTGGAAAAAGCTGCGGGGTATAAGGA
AATAAAGGCTGAAGGGGAGTTGACATGA

Upstream 100 bases:

>100_bases
TTACAGGGGGAAAATTTCTATTTTGGGGATGATATTGGGGGTCATAGGTGGTATAATAATAACAAGATATTTGTAAATCC
TTATTTTGCGAGGAGTGCCT

Downstream 100 bases:

>100_bases
GAGTTTTATTTGTGTGTACAGGGAATACCTGTAGAAGCCCTATGGCTGAAGGGATTTTTAATGCTAAGTCAAAAGCTTTG
GGCAAGGATTGGGAAGCAAA

Product: putative translation factor (Sua5)

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MMTKVIKIDKDNPEIELIDYAAEVIKKGGLVAFPTETVYGIGANSFDEEAVKRIFIAKGRPQDNPLILHIALMDQVYELA
AEFPEKAKKLAHRFWPGPLTVVLKKSDKVPYVNTAGMNTVAIRMPSNPIAHLLIKRAGVPISAPSANVSGKPSPTDASHV
IEDLYGKVDVIIDGGKCDVGLESTVVDLTEEVPVILRPGAVTLEMLKEVLGEVKLDPSLLTRPDENIKPKSPGMKYKHYS
PKAEVYIVKGPLDKVVKKIQQLAKNQLKNGKKVGIMATVQTSTQYKEGEIIVVGDRDKPETIAKNLFETLREFDRRGVEV
VFAESFNYDDIGLAIMNRLEKAAGYKEIKAEGELT

Sequences:

>Translated_355_residues
MMTKVIKIDKDNPEIELIDYAAEVIKKGGLVAFPTETVYGIGANSFDEEAVKRIFIAKGRPQDNPLILHIALMDQVYELA
AEFPEKAKKLAHRFWPGPLTVVLKKSDKVPYVNTAGMNTVAIRMPSNPIAHLLIKRAGVPISAPSANVSGKPSPTDASHV
IEDLYGKVDVIIDGGKCDVGLESTVVDLTEEVPVILRPGAVTLEMLKEVLGEVKLDPSLLTRPDENIKPKSPGMKYKHYS
PKAEVYIVKGPLDKVVKKIQQLAKNQLKNGKKVGIMATVQTSTQYKEGEIIVVGDRDKPETIAKNLFETLREFDRRGVEV
VFAESFNYDDIGLAIMNRLEKAAGYKEIKAEGELT
>Mature_355_residues
MMTKVIKIDKDNPEIELIDYAAEVIKKGGLVAFPTETVYGIGANSFDEEAVKRIFIAKGRPQDNPLILHIALMDQVYELA
AEFPEKAKKLAHRFWPGPLTVVLKKSDKVPYVNTAGMNTVAIRMPSNPIAHLLIKRAGVPISAPSANVSGKPSPTDASHV
IEDLYGKVDVIIDGGKCDVGLESTVVDLTEEVPVILRPGAVTLEMLKEVLGEVKLDPSLLTRPDENIKPKSPGMKYKHYS
PKAEVYIVKGPLDKVVKKIQQLAKNQLKNGKKVGIMATVQTSTQYKEGEIIVVGDRDKPETIAKNLFETLREFDRRGVEV
VFAESFNYDDIGLAIMNRLEKAAGYKEIKAEGELT

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=205, Percent_Identity=29.7560975609756, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081864, Length=203, Percent_Identity=32.0197044334975, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI2367210, Length=145, Percent_Identity=31.0344827586207, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537239, Length=219, Percent_Identity=32.8767123287671, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI193205175, Length=136, Percent_Identity=34.5588235294118, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=385, Percent_Identity=36.3636363636364, Blast_Score=215, Evalue=9e-57,
Organism=Drosophila melanogaster, GI78707274, Length=202, Percent_Identity=26.7326732673267, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 39088; Mature: 39088

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTKVIKIDKDNPEIELIDYAAEVIKKGGLVAFPTETVYGIGANSFDEEAVKRIFIAKGR
CCCEEEEEECCCCCEEEHHHHHHHHHCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCC
PQDNPLILHIALMDQVYELAAEFPEKAKKLAHRFWPGPLTVVLKKSDKVPYVNTAGMNTV
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCEE
AIRMPSNPIAHLLIKRAGVPISAPSANVSGKPSPTDASHVIEDLYGKVDVIIDGGKCDVG
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCC
LESTVVDLTEEVPVILRPGAVTLEMLKEVLGEVKLDPSLLTRPDENIKPKSPGMKYKHYS
CCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEECC
PKAEVYIVKGPLDKVVKKIQQLAKNQLKNGKKVGIMATVQTSTQYKEGEIIVVGDRDKPE
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEECCCCCHH
TIAKNLFETLREFDRRGVEVVFAESFNYDDIGLAIMNRLEKAAGYKEIKAEGELT
HHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCC
>Mature Secondary Structure
MMTKVIKIDKDNPEIELIDYAAEVIKKGGLVAFPTETVYGIGANSFDEEAVKRIFIAKGR
CCCEEEEEECCCCCEEEHHHHHHHHHCCCEEEECCCEEEECCCCCCHHHHHHHHHHCCCC
PQDNPLILHIALMDQVYELAAEFPEKAKKLAHRFWPGPLTVVLKKSDKVPYVNTAGMNTV
CCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCEE
AIRMPSNPIAHLLIKRAGVPISAPSANVSGKPSPTDASHVIEDLYGKVDVIIDGGKCDVG
EEECCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCC
LESTVVDLTEEVPVILRPGAVTLEMLKEVLGEVKLDPSLLTRPDENIKPKSPGMKYKHYS
CCHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCEEECC
PKAEVYIVKGPLDKVVKKIQQLAKNQLKNGKKVGIMATVQTSTQYKEGEIIVVGDRDKPE
CCCEEEEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCEEEECCCCCHH
TIAKNLFETLREFDRRGVEVVFAESFNYDDIGLAIMNRLEKAAGYKEIKAEGELT
HHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]