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The map label for this gene is zupT [H]

Identifier: 20806673

GI number: 20806673

Start: 142946

End: 143665

Strand: Direct

Name: zupT [H]

Synonym: TTE0144

Alternate gene names: 20806673

Gene position: 142946-143665 (Clockwise)

Preceding gene: 20806672

Following gene: 20806674

Centisome position: 5.32

GC content: 42.64

Gene sequence:

>720_bases
ATGTCAAATTTTGAGATATTGATGATAGGGGCTTTTGCAGGAGTAGCGGGGACAGGGCTGGGAGGGGTTTTTGCTTATTT
TTTTAAAAATCCAAACCCCAAATTTTTTAGTGGAATAATGGGGATTACAGCGGGACTCATGCTTTCTGTAGTGATGTTTG
ACCTGTTGCCCCATTCTTTTGAGATATCGGGGATGCCTGTAGGTGTCATTGGAGTCATTATCGGTGCTTTTCTTATTTCT
CTTTTTGATTCCCATATAGAAAAGACAAAATTTAATAAAGGATTTATTAGAGAAGGCTTGCTTCTAGGGATTGCAATAGC
TTTGCACAATTTTCCGGAAGGGCTTGCCGTAGGGTCTGGATTTATGGTATCTTCTTCTTTGGGCATTGATATTGCTTTGG
TGATTGCGCTACACGATTTCCCAGAAGGGGTAGCGGTGGCGGTGCCCCTTTCTGCAGGAGGGGTTTCCCCCTGCAAAGTT
TTGTTGTATACCTTTCTGACGGGGTTGCCGACTGCCCTTGGCACTTTTATAGGTATTTTGAGCGGTGGCATATCCAATAC
TTTTATTGGACTTAATCTTGCTCTGGCAGGAGGAGCGATGCTTTATGTGACCTGCGGTGAGATAATACCTGAGGCTAGGG
ATATTTACAGGGGGAAAATTTCTATTTTGGGGATGATATTGGGGGTCATAGGTGGTATAATAATAACAAGATATTTGTAA

Upstream 100 bases:

>100_bases
GTCCTCCTACCGTCGAGCGAGTTTTTTATTTTGCATAACTTTATGAGAAGTTTAATAAAGTAAAATTGAGATTGTTTCAT
AAATTCAAGGGGATGTTTTT

Downstream 100 bases:

>100_bases
ATCCTTATTTTGCGAGGAGTGCCTTTGATGACAAAGGTAATAAAAATTGACAAAGATAATCCCGAAATTGAGCTTATAGA
TTACGCTGCAGAGGTTATAA

Product: divalent heavy-metal cations transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSNFEILMIGAFAGVAGTGLGGVFAYFFKNPNPKFFSGIMGITAGLMLSVVMFDLLPHSFEISGMPVGVIGVIIGAFLIS
LFDSHIEKTKFNKGFIREGLLLGIAIALHNFPEGLAVGSGFMVSSSLGIDIALVIALHDFPEGVAVAVPLSAGGVSPCKV
LLYTFLTGLPTALGTFIGILSGGISNTFIGLNLALAGGAMLYVTCGEIIPEARDIYRGKISILGMILGVIGGIIITRYL

Sequences:

>Translated_239_residues
MSNFEILMIGAFAGVAGTGLGGVFAYFFKNPNPKFFSGIMGITAGLMLSVVMFDLLPHSFEISGMPVGVIGVIIGAFLIS
LFDSHIEKTKFNKGFIREGLLLGIAIALHNFPEGLAVGSGFMVSSSLGIDIALVIALHDFPEGVAVAVPLSAGGVSPCKV
LLYTFLTGLPTALGTFIGILSGGISNTFIGLNLALAGGAMLYVTCGEIIPEARDIYRGKISILGMILGVIGGIIITRYL
>Mature_238_residues
SNFEILMIGAFAGVAGTGLGGVFAYFFKNPNPKFFSGIMGITAGLMLSVVMFDLLPHSFEISGMPVGVIGVIIGAFLISL
FDSHIEKTKFNKGFIREGLLLGIAIALHNFPEGLAVGSGFMVSSSLGIDIALVIALHDFPEGVAVAVPLSAGGVSPCKVL
LYTFLTGLPTALGTFIGILSGGISNTFIGLNLALAGGAMLYVTCGEIIPEARDIYRGKISILGMILGVIGGIIITRYL

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577418, Length=141, Percent_Identity=36.8794326241135, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI229577422, Length=141, Percent_Identity=36.8794326241135, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI205830407, Length=123, Percent_Identity=32.520325203252, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI24586665, Length=123, Percent_Identity=32.520325203252, Blast_Score=64, Evalue=1e-10,
Organism=Homo sapiens, GI205830403, Length=123, Percent_Identity=32.520325203252, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1789419, Length=225, Percent_Identity=32.8888888888889, Blast_Score=78, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17507805, Length=150, Percent_Identity=36.6666666666667, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24652846, Length=136, Percent_Identity=36.0294117647059, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 24807; Mature: 24676

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFEILMIGAFAGVAGTGLGGVFAYFFKNPNPKFFSGIMGITAGLMLSVVMFDLLPHSF
CCCCEEEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
EISGMPVGVIGVIIGAFLISLFDSHIEKTKFNKGFIREGLLLGIAIALHNFPEGLAVGSG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FMVSSSLGIDIALVIALHDFPEGVAVAVPLSAGGVSPCKVLLYTFLTGLPTALGTFIGIL
EEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGGISNTFIGLNLALAGGAMLYVTCGEIIPEARDIYRGKISILGMILGVIGGIIITRYL
HCCCCHHEEEEEEEECCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNFEILMIGAFAGVAGTGLGGVFAYFFKNPNPKFFSGIMGITAGLMLSVVMFDLLPHSF
CCCEEEEEEEHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
EISGMPVGVIGVIIGAFLISLFDSHIEKTKFNKGFIREGLLLGIAIALHNFPEGLAVGSG
EECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
FMVSSSLGIDIALVIALHDFPEGVAVAVPLSAGGVSPCKVLLYTFLTGLPTALGTFIGIL
EEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SGGISNTFIGLNLALAGGAMLYVTCGEIIPEARDIYRGKISILGMILGVIGGIIITRYL
HCCCCHHEEEEEEEECCCEEEEEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA