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The map label for this gene is TatD [H]

Identifier: 20806640

GI number: 20806640

Start: 113540

End: 114310

Strand: Direct

Name: TatD [H]

Synonym: TTE0111

Alternate gene names: 20806640

Gene position: 113540-114310 (Clockwise)

Preceding gene: 20806639

Following gene: 20806641

Centisome position: 4.22

GC content: 36.84

Gene sequence:

>771_bases
TTGCTTATAGACTCTCACGCTCATCTTGAGGATGAGAAATACAATGAAGACAGGGAAAAAGTGATTGAGGAGTGCAAAAA
GGACCTCACATTTTTAATAAATGTGGGGTCCAATATATTGACTTCTAAAAAGACCATTGAACTTGCCCACAAATACGATT
TTATATACGCAACTGTGGGCATTCACCCTCATGATGCAGAAAGAGAAAAAGACAAAATAGAGGAAATAGAGAAGTTGGCT
CTTGAGGATAAAGTGGTGGCTATAGGAGAAATTGGCTTGGATTATTATTACGGTGACCCTCCTAAAGAATTTCAAATTGA
GGCTTTTGTGAAGCAGATAAGGCTCGCAAAAAAGCTTAAACTTCCCATTGTAATTCACGACAGAGTCGCCCATGAGGATA
TCTTAAAAATACTGAAAAAAGAATGGACACAGGATTTAAAAGGGGTATTTCACAGTTATTCTGGTAGTGTCGAGATGATA
AAAGAAGTGATAAGTATGAATTTTTACATCTCTCTTTCAGGAACTGTCACTTTCAAAAACGCTAAAAAAGTTAGGGAGGT
TGCAAAAGAAGTTCCTCTTGAATGGCTTTTGATTGAGACAGATAGTCCCTATTTGACTCCTGAGCCCTACAGAGGTAAGA
GAAACAAGCCCACATATGTTAAATTTGTAGCACAAAAAATTGCTGAAATAAAAGGTATAAGTTTTGAAGAAGTTTGTGAA
ACAACCTCGCAAAATGCCATAAAGCTTTTCAATTTGCCCTCCTGTTTTTGA

Upstream 100 bases:

>100_bases
CAGGGGATGCTATTGGCGGCCACTAATGAAGGGAAAATGGCGCTGTTGACGGTAGACAAAGACATAGAAAGCGGTTCTAA
AATAAGCTGAGGTGATAAAA

Downstream 100 bases:

>100_bases
TAGGTATCAAAAGTGTGAAAATTGCGTATAATAATTACATAACTGAAAAATTGTGTATAAAAATTTGACAAATTAATTTA
ATTGCATTAAAATTACTTAC

Product: Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MLIDSHAHLEDEKYNEDREKVIEECKKDLTFLINVGSNILTSKKTIELAHKYDFIYATVGIHPHDAEREKDKIEEIEKLA
LEDKVVAIGEIGLDYYYGDPPKEFQIEAFVKQIRLAKKLKLPIVIHDRVAHEDILKILKKEWTQDLKGVFHSYSGSVEMI
KEVISMNFYISLSGTVTFKNAKKVREVAKEVPLEWLLIETDSPYLTPEPYRGKRNKPTYVKFVAQKIAEIKGISFEEVCE
TTSQNAIKLFNLPSCF

Sequences:

>Translated_256_residues
MLIDSHAHLEDEKYNEDREKVIEECKKDLTFLINVGSNILTSKKTIELAHKYDFIYATVGIHPHDAEREKDKIEEIEKLA
LEDKVVAIGEIGLDYYYGDPPKEFQIEAFVKQIRLAKKLKLPIVIHDRVAHEDILKILKKEWTQDLKGVFHSYSGSVEMI
KEVISMNFYISLSGTVTFKNAKKVREVAKEVPLEWLLIETDSPYLTPEPYRGKRNKPTYVKFVAQKIAEIKGISFEEVCE
TTSQNAIKLFNLPSCF
>Mature_256_residues
MLIDSHAHLEDEKYNEDREKVIEECKKDLTFLINVGSNILTSKKTIELAHKYDFIYATVGIHPHDAEREKDKIEEIEKLA
LEDKVVAIGEIGLDYYYGDPPKEFQIEAFVKQIRLAKKLKLPIVIHDRVAHEDILKILKKEWTQDLKGVFHSYSGSVEMI
KEVISMNFYISLSGTVTFKNAKKVREVAKEVPLEWLLIETDSPYLTPEPYRGKRNKPTYVKFVAQKIAEIKGISFEEVCE
TTSQNAIKLFNLPSCF

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=264, Percent_Identity=31.4393939393939, Blast_Score=128, Evalue=4e-30,
Organism=Homo sapiens, GI110349734, Length=264, Percent_Identity=31.4393939393939, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI226061853, Length=270, Percent_Identity=31.8518518518519, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI226061614, Length=255, Percent_Identity=30.1960784313725, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI225903439, Length=246, Percent_Identity=31.3008130081301, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI14042943, Length=250, Percent_Identity=31.6, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI225903424, Length=161, Percent_Identity=37.2670807453416, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=28.5087719298246, Blast_Score=91, Evalue=8e-19,
Organism=Escherichia coli, GI1787342, Length=258, Percent_Identity=37.5968992248062, Blast_Score=195, Evalue=3e-51,
Organism=Escherichia coli, GI48994985, Length=261, Percent_Identity=34.0996168582375, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI87082439, Length=264, Percent_Identity=31.4393939393939, Blast_Score=141, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17559024, Length=280, Percent_Identity=32.1428571428571, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=28.1368821292776, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17543026, Length=220, Percent_Identity=32.2727272727273, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17565396, Length=219, Percent_Identity=32.4200913242009, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648690, Length=287, Percent_Identity=32.0557491289199, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24586117, Length=246, Percent_Identity=30.0813008130081, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221330018, Length=279, Percent_Identity=28.673835125448, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29565; Mature: 29565

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHAHLEDEKYNEDREKVIEECKKDLTFLINVGSNILTSKKTIELAHKYDFIYATVG
CEECCCCCCCCHHCCCHHHHHHHHHHHHHEEEEECCCCHHCCHHHHHHHHHHEEEEEEEC
IHPHDAEREKDKIEEIEKLALEDKVVAIGEIGLDYYYGDPPKEFQIEAFVKQIRLAKKLK
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHC
LPIVIHDRVAHEDILKILKKEWTQDLKGVFHSYSGSVEMIKEVISMNFYISLSGTVTFKN
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEECEEEECC
AKKVREVAKEVPLEWLLIETDSPYLTPEPYRGKRNKPTYVKFVAQKIAEIKGISFEEVCE
HHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
TTSQNAIKLFNLPSCF
HCCCCCEEEECCCCCC
>Mature Secondary Structure
MLIDSHAHLEDEKYNEDREKVIEECKKDLTFLINVGSNILTSKKTIELAHKYDFIYATVG
CEECCCCCCCCHHCCCHHHHHHHHHHHHHEEEEECCCCHHCCHHHHHHHHHHEEEEEEEC
IHPHDAEREKDKIEEIEKLALEDKVVAIGEIGLDYYYGDPPKEFQIEAFVKQIRLAKKLK
CCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHC
LPIVIHDRVAHEDILKILKKEWTQDLKGVFHSYSGSVEMIKEVISMNFYISLSGTVTFKN
CCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEEECEEEECC
AKKVREVAKEVPLEWLLIETDSPYLTPEPYRGKRNKPTYVKFVAQKIAEIKGISFEEVCE
HHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
TTSQNAIKLFNLPSCF
HCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]