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The map label for this gene is LepB [H]

Identifier: 20806565

GI number: 20806565

Start: 27991

End: 28521

Strand: Direct

Name: LepB [H]

Synonym: TTE0024

Alternate gene names: 20806565

Gene position: 27991-28521 (Clockwise)

Preceding gene: 20806563

Following gene: 20806566

Centisome position: 1.04

GC content: 36.91

Gene sequence:

>531_bases
ATGAGCAAAAATATAGGAAAAGAGATATTAAGCTGGATATTTACTATACTTCTCGCTTTCGCAATTGCCCTTTTCATTAG
GACTTATGTGTTTGAGCTGGTGGATGTCCCTACGGGTTCAATGATGGACACAATACACATAAACGACAAATTCATTGTGA
ACAAATTTATATACAGATTTGAACCTGTCAAAAGAGGAGACATTGTAGTATTTCGTTTTCCTGACAATCCAAAAGTTAAT
TTTGTGAAAAGAGTGATAGGAATAGGAGGAGATGTCATAGAAATAAAAGATGGAAAACTCATAAGAAACGGAAAGGTTGT
AAATGAGCCTTATGTAAAAGAACCCATGAAAGGAAATTTTGGCCCTTATGTGGTGCCTCCAGGCCACTATTTTATGTTGG
GAGACAATCGGAACGAATCTATGGACAGCCGATTTTGGCAGCACAAATACGTATCAAAGGATCAAATTTTGGGCAAAGTA
GTATTTAGGATATGGCCTCCAAATAGAATTGGCAGTATGGAGGGAAAATGA

Upstream 100 bases:

>100_bases
TTATTATTGACAAATATTAGCAAAAATATACAAGGAAGATTAGAATTTATTTGAAGTTTATGCTATAATATCATTGTACT
TTCAAGTGAGGAGAGTCAGT

Downstream 100 bases:

>100_bases
GGGTTGAAAATACTTTAATAAAGTAGTATAATAATTTAAAAAGTGAATAACTTTAGGCGATGAAGGGACGAGTAGTAAGT
AAAGACTTTTAAGAGAGCTG

Product: Signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MSKNIGKEILSWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRFEPVKRGDIVVFRFPDNPKVN
FVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKV
VFRIWPPNRIGSMEGK

Sequences:

>Translated_176_residues
MSKNIGKEILSWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRFEPVKRGDIVVFRFPDNPKVN
FVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKV
VFRIWPPNRIGSMEGK
>Mature_175_residues
SKNIGKEILSWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRFEPVKRGDIVVFRFPDNPKVNF
VKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNFGPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKVV
FRIWPPNRIGSMEGK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=91, Percent_Identity=37.3626373626374, Blast_Score=71, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 20344; Mature: 20213

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNIGKEILSWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHC
EPVKRGDIVVFRFPDNPKVNFVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNF
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCEEEECCEECCCCCCCCCCCCCC
GPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKVVFRIWPPNRIGSMEGK
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCC
>Mature Secondary Structure 
SKNIGKEILSWIFTILLAFAIALFIRTYVFELVDVPTGSMMDTIHINDKFIVNKFIYRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHC
EPVKRGDIVVFRFPDNPKVNFVKRVIGIGGDVIEIKDGKLIRNGKVVNEPYVKEPMKGNF
CCCCCCCEEEEECCCCCCHHHHHHHHHCCCCEEEEECCEEEECCEECCCCCCCCCCCCCC
GPYVVPPGHYFMLGDNRNESMDSRFWQHKYVSKDQILGKVVFRIWPPNRIGSMEGK
CCEEECCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7865790 [H]