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The map label for this gene is yicI [C]

Identifier: 20806548

GI number: 20806548

Start: 4653

End: 6908

Strand: Direct

Name: yicI [C]

Synonym: TTE0006

Alternate gene names: 20806548

Gene position: 4653-6908 (Clockwise)

Preceding gene: 20806547

Following gene: 20806552

Centisome position: 0.17

GC content: 36.75

Gene sequence:

>2256_bases
ATGCTTCAAAGAACTGTTGAGGGAATTGTAGTTAGATCCGAAGGCAAAAAATTAGAGTTGAGAGTGATAACAGACAAGAT
AGTCAACATTTTTGTCACTGACAAGGAAGAAAAGAGAAGAGATACAATTGCCATAGAAAAGAAAAAATATGACATTCCTG
ATTTCAATGTAGAGGAAAGCAAAGACAAGGTGCTTGTACTTACAAAAGACCTCAAAGTAGAAATAGATAAAAAAACATTT
TTTATCACCTTTAAAGATAAAGATGGCGATGTGATTAATGAAGATTACGGGGAAGGTGTAAAGTTAGGCGACTCAGAGGT
TAGGTGTTATAAGAAGCTTAGAGAAGACCATTTTTACGGCTTTGGCGAAAAAGCTGGTTATCTTGATAAAAAAGGTGAAA
AGTTTGAAATGTGGAATACTGACGAATTTATGACTCACAATCAAACTACCAAGCTTTTGTATGAGTCATATCCCTTTTTT
ATAGGAATGAATAAAAAGCATACGTATGGAATTTTTTTAGACAACAGCTTCAGAAGCTTTTTTAACATGGGAGAAGAAAG
CGAAGAGTACTATTATTTTGGGGCATATGGAGGGCAGATGAATTATTACTTCATTTACGGAAATGACATAAAAGAGGTAG
TAGAAAATTATACATATTTGACTGGAAGGATTGAACTTCCTCCTTTGTGGGCTTTAGGAAACCAGCAGAGCAGATACAGC
TATACTCCTCAGGAGAAAGTGCTTGAAGTAGCTAAGACTTTCAGAGAAAAAGACATACCTTGTGATGTGATCTATTTAGA
CATAGACTATATGGAAGGGTATAGGGTTTTTACCTGGAACAAGGGTACTTTTAAAAATTATAAGGAAATGCTGAAAAATC
TAAAGAGCATGGGATTTAAAGTAGTTACAATTGTTGACCCGGGAGTTAAAAGAGATTATGAGTATTTTGTTTATAGAGAA
GGGATTGAAAATGATTATTTTGTCAAGGATAAGTATGGCATTACATATGTAGGAAAAGTGTGGCCTGGAGAGGCTTGCTT
CCCAGATTTCCTGCAGGATAAGGTGAGGAAATGGTGGGGAGAAAAGATTGCTAATTTTGTAAGAGATGGAATCGATGGGA
TATGGAATGACATGAACGAACCAGCTGTTTTTGAAACTCCTACAAAAACTATGCCGGAAGATAATATCCATATTCTAGAT
GGGGAGAAAATAAGCCACAGAGAAGCTCACAATGTATATGCTAACTACATGGCTCTTGCGACTAAAGAAGGCCTTTTAAA
GGAAAGAACTAATGAAAGGCCCTTTATCCTCACAAGAGCAGCATTTGCTGGAATACAGAGATATGCTGCCATGTGGACAG
GAGATAATAGAAGCCTTTATGAGCACCTCCTCATGATGATGCCTATGCTTATGAACGTAGGTCTGTCTGGACAACCGTTT
GCGGGAGCTGACGTAGGAGGGTTTGAGGGAGATTGCAGTGAAGAGCTTTTCATAAGGTGGATAGAAGCTGCTGTTTTTAC
TCCTTTTTTAAGAGTTCACTCTGCTATAGGGACGAAAGACCAAGAGCCGTGGTCTTTTGGAAAAAAGGCAGAGGATATTG
CTAGAAAATTTATAAAAATAAGGTATGAGCTTTTGCCCTACATTTATGATTTGTTTTATGAAGCCTCGAAGAAGGGCTAT
CCTGTAATGAGACCTCTAGTTTTTGAGTATCAGGAGGATGAGAATACTCACAAAATTTATGACGAATTTATGCTTGGGCA
AAATTTACTCATAGCTCCAGTATATCTCCCCTCCAAAGATAGAAGGGAAGTGTACTTGCCTTCAGGTATTTGGTATGACT
ATTTTATGGGAGAGAGGTACGAAGGGGGAAATTATTATTTAGTAGAAGCTCCCATCGATACAATTCCTGTTTTTGTAAAA
GAAGGAGCTATAATTGTAAAACAAAAGCCCCTTTCATATGTGGAAGAAGATAGAATAGAGGAGAAGGTGGTTGAGATATA
TAGGGGAAATAGAGGAAGATATGTTCACTACGAGGATGATGGAAAAACCTTTGATTACAAGAAAGGAGTGTATAACCTCT
TTGAGATAGAGTTTGAATACTTCGATGGAGAAATTGATATAAAATTCGATAAAGTGCACTTTGGGTATGAGGATGGAGCA
AAAAAGTATAGATTTGTACTAAAGAATTTTGATGAGGTGAAAAAAGTCAAAATAAATGGAGAAGAAGTAGAAGAGTATGA
GATTGTAGTGAAATAG

Upstream 100 bases:

>100_bases
TGACTGAAAGGGATAAAAAAAGTATCATTTATCTATCTCCTATCTCAGCTGTAACGCTGATAAAAAGAGCTCACAAAATA
TTCGAATGAGGAGGCTTAAG

Downstream 100 bases:

>100_bases
GCTGCATAAAGGCAGCTTATTGGCTTGTTGACAAAGTTCCCCTTATTTAAGTGGCATTTTGTGTTAATGCTCCAGAGTTG
CAAAGCGACTAAACTAAAGC

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 751; Mature: 751

Protein sequence:

>751_residues
MLQRTVEGIVVRSEGKKLELRVITDKIVNIFVTDKEEKRRDTIAIEKKKYDIPDFNVEESKDKVLVLTKDLKVEIDKKTF
FITFKDKDGDVINEDYGEGVKLGDSEVRCYKKLREDHFYGFGEKAGYLDKKGEKFEMWNTDEFMTHNQTTKLLYESYPFF
IGMNKKHTYGIFLDNSFRSFFNMGEESEEYYYFGAYGGQMNYYFIYGNDIKEVVENYTYLTGRIELPPLWALGNQQSRYS
YTPQEKVLEVAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKGTFKNYKEMLKNLKSMGFKVVTIVDPGVKRDYEYFVYRE
GIENDYFVKDKYGITYVGKVWPGEACFPDFLQDKVRKWWGEKIANFVRDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKISHREAHNVYANYMALATKEGLLKERTNERPFILTRAAFAGIQRYAAMWTGDNRSLYEHLLMMMPMLMNVGLSGQPF
AGADVGGFEGDCSEELFIRWIEAAVFTPFLRVHSAIGTKDQEPWSFGKKAEDIARKFIKIRYELLPYIYDLFYEASKKGY
PVMRPLVFEYQEDENTHKIYDEFMLGQNLLIAPVYLPSKDRREVYLPSGIWYDYFMGERYEGGNYYLVEAPIDTIPVFVK
EGAIIVKQKPLSYVEEDRIEEKVVEIYRGNRGRYVHYEDDGKTFDYKKGVYNLFEIEFEYFDGEIDIKFDKVHFGYEDGA
KKYRFVLKNFDEVKKVKINGEEVEEYEIVVK

Sequences:

>Translated_751_residues
MLQRTVEGIVVRSEGKKLELRVITDKIVNIFVTDKEEKRRDTIAIEKKKYDIPDFNVEESKDKVLVLTKDLKVEIDKKTF
FITFKDKDGDVINEDYGEGVKLGDSEVRCYKKLREDHFYGFGEKAGYLDKKGEKFEMWNTDEFMTHNQTTKLLYESYPFF
IGMNKKHTYGIFLDNSFRSFFNMGEESEEYYYFGAYGGQMNYYFIYGNDIKEVVENYTYLTGRIELPPLWALGNQQSRYS
YTPQEKVLEVAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKGTFKNYKEMLKNLKSMGFKVVTIVDPGVKRDYEYFVYRE
GIENDYFVKDKYGITYVGKVWPGEACFPDFLQDKVRKWWGEKIANFVRDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKISHREAHNVYANYMALATKEGLLKERTNERPFILTRAAFAGIQRYAAMWTGDNRSLYEHLLMMMPMLMNVGLSGQPF
AGADVGGFEGDCSEELFIRWIEAAVFTPFLRVHSAIGTKDQEPWSFGKKAEDIARKFIKIRYELLPYIYDLFYEASKKGY
PVMRPLVFEYQEDENTHKIYDEFMLGQNLLIAPVYLPSKDRREVYLPSGIWYDYFMGERYEGGNYYLVEAPIDTIPVFVK
EGAIIVKQKPLSYVEEDRIEEKVVEIYRGNRGRYVHYEDDGKTFDYKKGVYNLFEIEFEYFDGEIDIKFDKVHFGYEDGA
KKYRFVLKNFDEVKKVKINGEEVEEYEIVVK
>Mature_751_residues
MLQRTVEGIVVRSEGKKLELRVITDKIVNIFVTDKEEKRRDTIAIEKKKYDIPDFNVEESKDKVLVLTKDLKVEIDKKTF
FITFKDKDGDVINEDYGEGVKLGDSEVRCYKKLREDHFYGFGEKAGYLDKKGEKFEMWNTDEFMTHNQTTKLLYESYPFF
IGMNKKHTYGIFLDNSFRSFFNMGEESEEYYYFGAYGGQMNYYFIYGNDIKEVVENYTYLTGRIELPPLWALGNQQSRYS
YTPQEKVLEVAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKGTFKNYKEMLKNLKSMGFKVVTIVDPGVKRDYEYFVYRE
GIENDYFVKDKYGITYVGKVWPGEACFPDFLQDKVRKWWGEKIANFVRDGIDGIWNDMNEPAVFETPTKTMPEDNIHILD
GEKISHREAHNVYANYMALATKEGLLKERTNERPFILTRAAFAGIQRYAAMWTGDNRSLYEHLLMMMPMLMNVGLSGQPF
AGADVGGFEGDCSEELFIRWIEAAVFTPFLRVHSAIGTKDQEPWSFGKKAEDIARKFIKIRYELLPYIYDLFYEASKKGY
PVMRPLVFEYQEDENTHKIYDEFMLGQNLLIAPVYLPSKDRREVYLPSGIWYDYFMGERYEGGNYYLVEAPIDTIPVFVK
EGAIIVKQKPLSYVEEDRIEEKVVEIYRGNRGRYVHYEDDGKTFDYKKGVYNLFEIEFEYFDGEIDIKFDKVHFGYEDGA
KKYRFVLKNFDEVKKVKINGEEVEEYEIVVK

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI66346737, Length=605, Percent_Identity=36.198347107438, Blast_Score=386, Evalue=1e-107,
Organism=Homo sapiens, GI88900491, Length=610, Percent_Identity=35.7377049180328, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI38202257, Length=610, Percent_Identity=35.7377049180328, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI119393895, Length=697, Percent_Identity=30.12912482066, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI119393893, Length=697, Percent_Identity=30.12912482066, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI119393891, Length=697, Percent_Identity=30.12912482066, Blast_Score=326, Evalue=5e-89,
Organism=Homo sapiens, GI221316699, Length=702, Percent_Identity=31.0541310541311, Blast_Score=311, Evalue=2e-84,
Organism=Homo sapiens, GI157364974, Length=759, Percent_Identity=29.7760210803689, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI310115361, Length=607, Percent_Identity=27.3476112026359, Blast_Score=236, Evalue=4e-62,
Organism=Homo sapiens, GI153791946, Length=463, Percent_Identity=26.3498920086393, Blast_Score=133, Evalue=7e-31,
Organism=Escherichia coli, GI2367256, Length=536, Percent_Identity=26.6791044776119, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI2367323, Length=570, Percent_Identity=26.140350877193, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71991189, Length=634, Percent_Identity=35.4889589905363, Blast_Score=379, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17560798, Length=624, Percent_Identity=33.1730769230769, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17560800, Length=624, Percent_Identity=33.1730769230769, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI71985706, Length=646, Percent_Identity=28.328173374613, Blast_Score=241, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI32563849, Length=691, Percent_Identity=28.0752532561505, Blast_Score=229, Evalue=4e-60,
Organism=Saccharomyces cerevisiae, GI6319706, Length=617, Percent_Identity=33.387358184765, Blast_Score=325, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24643749, Length=590, Percent_Identity=34.2372881355932, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24643753, Length=590, Percent_Identity=34.2372881355932, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24643751, Length=590, Percent_Identity=34.2372881355932, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24643746, Length=590, Percent_Identity=34.2372881355932, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI21357605, Length=590, Percent_Identity=34.2372881355932, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24650054, Length=388, Percent_Identity=28.3505154639175, Blast_Score=149, Evalue=9e-36,
Organism=Drosophila melanogaster, GI28571438, Length=399, Percent_Identity=22.8070175438596, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI28571440, Length=398, Percent_Identity=22.6130653266332, Blast_Score=73, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 88570; Mature: 88570

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQRTVEGIVVRSEGKKLELRVITDKIVNIFVTDKEEKRRDTIAIEKKKYDIPDFNVEES
CCCCCCCEEEEECCCCEEEEEEEEEEEEEEEEECCHHHCCCCEEEEECCCCCCCCCCCCC
KDKVLVLTKDLKVEIDKKTFFITFKDKDGDVINEDYGEGVKLGDSEVRCYKKLREDHFYG
CCCEEEEEECCEEEEECEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FGEKAGYLDKKGEKFEMWNTDEFMTHNQTTKLLYESYPFFIGMNKKHTYGIFLDNSFRSF
CCCCCCCCCCCCCEEEECCCHHHHCCCCHHHHHHCCCCEEEECCCCEEEEEEEECCHHHH
FNMGEESEEYYYFGAYGGQMNYYFIYGNDIKEVVENYTYLTGRIELPPLWALGNQQSRYS
HCCCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHCCEEEEEEEECCCEEECCCCCCCCC
YTPQEKVLEVAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKGTFKNYKEMLKNLKSMGFK
CCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCEE
VVTIVDPGVKRDYEYFVYREGIENDYFVKDKYGITYVGKVWPGEACFPDFLQDKVRKWWG
EEEEECCCCCCCCEEEEEECCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
EKIANFVRDGIDGIWNDMNEPAVFETPTKTMPEDNIHILDGEKISHREAHNVYANYMALA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TKEGLLKERTNERPFILTRAAFAGIQRYAAMWTGDNRSLYEHLLMMMPMLMNVGLSGQPF
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
AGADVGGFEGDCSEELFIRWIEAAVFTPFLRVHSAIGTKDQEPWSFGKKAEDIARKFIKI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RYELLPYIYDLFYEASKKGYPVMRPLVFEYQEDENTHKIYDEFMLGQNLLIAPVYLPSKD
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCC
RREVYLPSGIWYDYFMGERYEGGNYYLVEAPIDTIPVFVKEGAIIVKQKPLSYVEEDRIE
CCEEECCCCCEEEHHCCCEEECCCEEEEECCCCCCCEEEECCEEEEECCCCHHHHHHHHH
EKVVEIYRGNRGRYVHYEDDGKTFDYKKGVYNLFEIEFEYFDGEIDIKFDKVHFGYEDGA
HHHHHHHCCCCCCEEEECCCCCEECHHCCCEEEEEEEEEEECCEEEEEEEEEEECCCCCH
KKYRFVLKNFDEVKKVKINGEEVEEYEIVVK
HHHHHHHHCCCCCEEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MLQRTVEGIVVRSEGKKLELRVITDKIVNIFVTDKEEKRRDTIAIEKKKYDIPDFNVEES
CCCCCCCEEEEECCCCEEEEEEEEEEEEEEEEECCHHHCCCCEEEEECCCCCCCCCCCCC
KDKVLVLTKDLKVEIDKKTFFITFKDKDGDVINEDYGEGVKLGDSEVRCYKKLREDHFYG
CCCEEEEEECCEEEEECEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
FGEKAGYLDKKGEKFEMWNTDEFMTHNQTTKLLYESYPFFIGMNKKHTYGIFLDNSFRSF
CCCCCCCCCCCCCEEEECCCHHHHCCCCHHHHHHCCCCEEEECCCCEEEEEEEECCHHHH
FNMGEESEEYYYFGAYGGQMNYYFIYGNDIKEVVENYTYLTGRIELPPLWALGNQQSRYS
HCCCCCCCCEEEEEEECCCEEEEEEECCCHHHHHHCCEEEEEEEECCCEEECCCCCCCCC
YTPQEKVLEVAKTFREKDIPCDVIYLDIDYMEGYRVFTWNKGTFKNYKEMLKNLKSMGFK
CCCHHHHHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHCCEE
VVTIVDPGVKRDYEYFVYREGIENDYFVKDKYGITYVGKVWPGEACFPDFLQDKVRKWWG
EEEEECCCCCCCCEEEEEECCCCCCEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
EKIANFVRDGIDGIWNDMNEPAVFETPTKTMPEDNIHILDGEKISHREAHNVYANYMALA
HHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHH
TKEGLLKERTNERPFILTRAAFAGIQRYAAMWTGDNRSLYEHLLMMMPMLMNVGLSGQPF
HHHHHHHHCCCCCCEEEEHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHHCCCCCCCC
AGADVGGFEGDCSEELFIRWIEAAVFTPFLRVHSAIGTKDQEPWSFGKKAEDIARKFIKI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
RYELLPYIYDLFYEASKKGYPVMRPLVFEYQEDENTHKIYDEFMLGQNLLIAPVYLPSKD
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEEECCCCC
RREVYLPSGIWYDYFMGERYEGGNYYLVEAPIDTIPVFVKEGAIIVKQKPLSYVEEDRIE
CCEEECCCCCEEEHHCCCEEECCCEEEEECCCCCCCEEEECCEEEEECCCCHHHHHHHHH
EKVVEIYRGNRGRYVHYEDDGKTFDYKKGVYNLFEIEFEYFDGEIDIKFDKVHFGYEDGA
HHHHHHHCCCCCCEEEECCCCCEECHHCCCEEEEEEEEEEECCEEEEEEEEEEECCCCCH
KKYRFVLKNFDEVKKVKINGEEVEEYEIVVK
HHHHHHHHCCCCCEEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]