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The map label for this gene is cpsG [H]

Identifier: 203284736

GI number: 203284736

Start: 911199

End: 912908

Strand: Reverse

Name: cpsG [H]

Synonym: BDU_848

Alternate gene names: 203284736

Gene position: 912908-911199 (Counterclockwise)

Preceding gene: 203284740

Following gene: 203284735

Centisome position: 97.99

GC content: 26.9

Gene sequence:

>1710_bases
ATGAAAAATAATAAACTTCAAAAAAAATTAAAACAATATATACAATTTGAAAAAAACAATTTTTTTAAAGATGAAGCTAT
CAAATTGCTTAAAGAAAATAATGAAACAGAAATATACAATAGATTTCACAAAGAACTAGAATTTGGTACTGCTGGCATGA
GAGGTATAATTGGGGCTGGATCATGCTATATTAATACATACAACATCGCCAAAGCAAGTCAAGGAATTGCCAACTATATC
CTTACAATAACACAAAATCCTAAAATCGCAATAAGTTATGACTCAAGACATTTTTCAAAAGAATTTGCATACGAAGCTGC
GGAAATTTTTGCCTCAAATGGGATTAAAGTTTACATATATAAAAATTTAAGAACAACTCCACAATTATCCTACACAGTTA
GAAAATTAAACTGCGATCTTGGAATAATGATAACAGCAAGTCATAATACAAAAGAATACAACGGATATAAAGTATACTGG
AAAGGAGGTGCTCAAATAATAGATCCACATGATGCAAAAATAATATCGGAAATACAAAAAGTATCTAATATCAAACATAC
ATTAATAAAAAGAGAAGGAATAAATAAAAGAATAATAATTGAACTTAAAAATGAAATTGATATTAAATACATACAAAAAA
TAAATGACGAATTTCCTAATTTCAATCAAAAAAGTAAAACTACAAATTTACGAATCGCATATACTCCTTTGCATGGAACA
GGAGGAACAATAATAAAGAAATTATTTAAAGGTAGCAAAGTAGAACTTTTAACAGAACAAACACAAATAAATCCTGATCC
AGAATTTCCTACAGTCAAATATCCCAATCCTGAAGAACATACAACCATGTCTAGAGTAATAGAACTTGCAAAGAAAACAA
ACTGTGATATTGCATTTGCAACAGATCCAGATGCTGATCGATTGGGTATTGCTTTCAAAGAAAACAGAAAATGGAAAATT
TTAAATGGAAATCAAATTGCATGCATCTTAATGCACTATTTACTATCTAGAGAAAACAACCCCAAAAACACCTTTATAAT
AGCCTCTTTTGTCACAACCCCAATGTTAGATAAAATAGCTCAAAAATTCAACACAACATTATATAGAACATATACAGGAT
TTAAATGGATAGGAAACTTAATAGATAAGATACAAAAAAAAGAACCAAACAAAAAATTTATTTTTGGATGTGAAGAAAGC
CATGGATACCTAATTGGCACTGGAACTAGAGATAAAGATGCATTTTCAGCCATAAAAGGATTTTGTGATTTAATGTTTAC
ACTAAAAAAAAACCAAATCACAATAAATCAATATCTACAAACAATGTACAAAGAATTTGGATATTACGAAGATTTTACAA
TTAATAAAATCTTTAAAGAAACTAATGGTGATTTTTTAAGAGAAAAATTAATGTTACAATTTAGAAACAATATTACAAAA
GAATTTGCAGGTCTTTTCATAATTAAAAAATTAGATTATAAAACACTAAAAGAAATCGATATGCATGGAAACATATATAC
AATAAAAGGCTATACACACACCACAAATGCAATAAAATTCTTATTAGAAAATAAAATCGAAATAACAATTAGGCCATCTG
GCACGGAAGCAAAAATTAAATTTTATATATCCATATATTCAAGATACGAACAAAAAAATAGTATTTTTGATATAATGAAC
AAAATAAAGATGGAGATAGAAAAATATTAA

Upstream 100 bases:

>100_bases
AAAGATTATAAATCAAATATAATAATCAACTCTACAGTTATATTTTATTATTTTATAATTTAATTATAAATTCTCAAATA
ACAAAATAAAGGAAAATAAT

Downstream 100 bases:

>100_bases
TATAACAGACAAATTAATGAACCTAGTTGAAATATCGTCAAGAGAAGTAGCTAGAAAAAATAAAAATAGAGAAGTCTCAA
GTTGGCATTTATTAATGTCT

Product: phosphomannomutase

Products: NA

Alternate protein names: PGM; Alpha-phosphoglucomutase; Glucose phosphomutase [H]

Number of amino acids: Translated: 569; Mature: 569

Protein sequence:

>569_residues
MKNNKLQKKLKQYIQFEKNNFFKDEAIKLLKENNETEIYNRFHKELEFGTAGMRGIIGAGSCYINTYNIAKASQGIANYI
LTITQNPKIAISYDSRHFSKEFAYEAAEIFASNGIKVYIYKNLRTTPQLSYTVRKLNCDLGIMITASHNTKEYNGYKVYW
KGGAQIIDPHDAKIISEIQKVSNIKHTLIKREGINKRIIIELKNEIDIKYIQKINDEFPNFNQKSKTTNLRIAYTPLHGT
GGTIIKKLFKGSKVELLTEQTQINPDPEFPTVKYPNPEEHTTMSRVIELAKKTNCDIAFATDPDADRLGIAFKENRKWKI
LNGNQIACILMHYLLSRENNPKNTFIIASFVTTPMLDKIAQKFNTTLYRTYTGFKWIGNLIDKIQKKEPNKKFIFGCEES
HGYLIGTGTRDKDAFSAIKGFCDLMFTLKKNQITINQYLQTMYKEFGYYEDFTINKIFKETNGDFLREKLMLQFRNNITK
EFAGLFIIKKLDYKTLKEIDMHGNIYTIKGYTHTTNAIKFLLENKIEITIRPSGTEAKIKFYISIYSRYEQKNSIFDIMN
KIKMEIEKY

Sequences:

>Translated_569_residues
MKNNKLQKKLKQYIQFEKNNFFKDEAIKLLKENNETEIYNRFHKELEFGTAGMRGIIGAGSCYINTYNIAKASQGIANYI
LTITQNPKIAISYDSRHFSKEFAYEAAEIFASNGIKVYIYKNLRTTPQLSYTVRKLNCDLGIMITASHNTKEYNGYKVYW
KGGAQIIDPHDAKIISEIQKVSNIKHTLIKREGINKRIIIELKNEIDIKYIQKINDEFPNFNQKSKTTNLRIAYTPLHGT
GGTIIKKLFKGSKVELLTEQTQINPDPEFPTVKYPNPEEHTTMSRVIELAKKTNCDIAFATDPDADRLGIAFKENRKWKI
LNGNQIACILMHYLLSRENNPKNTFIIASFVTTPMLDKIAQKFNTTLYRTYTGFKWIGNLIDKIQKKEPNKKFIFGCEES
HGYLIGTGTRDKDAFSAIKGFCDLMFTLKKNQITINQYLQTMYKEFGYYEDFTINKIFKETNGDFLREKLMLQFRNNITK
EFAGLFIIKKLDYKTLKEIDMHGNIYTIKGYTHTTNAIKFLLENKIEITIRPSGTEAKIKFYISIYSRYEQKNSIFDIMN
KIKMEIEKY
>Mature_569_residues
MKNNKLQKKLKQYIQFEKNNFFKDEAIKLLKENNETEIYNRFHKELEFGTAGMRGIIGAGSCYINTYNIAKASQGIANYI
LTITQNPKIAISYDSRHFSKEFAYEAAEIFASNGIKVYIYKNLRTTPQLSYTVRKLNCDLGIMITASHNTKEYNGYKVYW
KGGAQIIDPHDAKIISEIQKVSNIKHTLIKREGINKRIIIELKNEIDIKYIQKINDEFPNFNQKSKTTNLRIAYTPLHGT
GGTIIKKLFKGSKVELLTEQTQINPDPEFPTVKYPNPEEHTTMSRVIELAKKTNCDIAFATDPDADRLGIAFKENRKWKI
LNGNQIACILMHYLLSRENNPKNTFIIASFVTTPMLDKIAQKFNTTLYRTYTGFKWIGNLIDKIQKKEPNKKFIFGCEES
HGYLIGTGTRDKDAFSAIKGFCDLMFTLKKNQITINQYLQTMYKEFGYYEDFTINKIFKETNGDFLREKLMLQFRNNITK
EFAGLFIIKKLDYKTLKEIDMHGNIYTIKGYTHTTNAIKFLLENKIEITIRPSGTEAKIKFYISIYSRYEQKNSIFDIMN
KIKMEIEKY

Specific function: Catalyzes the interconversion between glucose-6- phosphate and alpha-glucose-1-phosphate. This is the first step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI31377548, Length=596, Percent_Identity=32.2147651006711, Blast_Score=273, Evalue=3e-73,
Organism=Homo sapiens, GI63055049, Length=589, Percent_Identity=32.258064516129, Blast_Score=269, Evalue=6e-72,
Organism=Escherichia coli, GI1786904, Length=550, Percent_Identity=22.1818181818182, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993870, Length=569, Percent_Identity=29.1739894551845, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI71993878, Length=328, Percent_Identity=33.2317073170732, Blast_Score=189, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323934, Length=611, Percent_Identity=29.9509001636661, Blast_Score=227, Evalue=4e-60,
Organism=Drosophila melanogaster, GI20129809, Length=576, Percent_Identity=28.4722222222222, Blast_Score=254, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24651977, Length=467, Percent_Identity=30.406852248394, Blast_Score=240, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24653722, Length=587, Percent_Identity=25.5536626916525, Blast_Score=214, Evalue=1e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 66191; Mature: 66191

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNKLQKKLKQYIQFEKNNFFKDEAIKLLKENNETEIYNRFHKELEFGTAGMRGIIGAG
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEECC
SCYINTYNIAKASQGIANYILTITQNPKIAISYDSRHFSKEFAYEAAEIFASNGIKVYIY
EEEEEEEEHHHHHCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEE
KNLRTTPQLSYTVRKLNCDLGIMITASHNTKEYNGYKVYWKGGAQIIDPHDAKIISEIQK
ECCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHH
VSNIKHTLIKREGINKRIIIELKNEIDIKYIQKINDEFPNFNQKSKTTNLRIAYTPLHGT
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
GGTIIKKLFKGSKVELLTEQTQINPDPEFPTVKYPNPEEHTTMSRVIELAKKTNCDIAFA
CHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
TDPDADRLGIAFKENRKWKILNGNQIACILMHYLLSRENNPKNTFIIASFVTTPMLDKIA
CCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
QKFNTTLYRTYTGFKWIGNLIDKIQKKEPNKKFIFGCEESHGYLIGTGTRDKDAFSAIKG
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCHHHHHHHHH
FCDLMFTLKKNQITINQYLQTMYKEFGYYEDFTINKIFKETNGDFLREKLMLQFRNNITK
HHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EFAGLFIIKKLDYKTLKEIDMHGNIYTIKGYTHTTNAIKFLLENKIEITIRPSGTEAKIK
HHHHEEEEEECCHHHHHHHHCCCCEEEEECCEEHHHHHHHHCCCCEEEEEECCCCCEEEE
FYISIYSRYEQKNSIFDIMNKIKMEIEKY
EEEEEHHHHHHCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNNKLQKKLKQYIQFEKNNFFKDEAIKLLKENNETEIYNRFHKELEFGTAGMRGIIGAG
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCEECC
SCYINTYNIAKASQGIANYILTITQNPKIAISYDSRHFSKEFAYEAAEIFASNGIKVYIY
EEEEEEEEHHHHHCCCEEEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEE
KNLRTTPQLSYTVRKLNCDLGIMITASHNTKEYNGYKVYWKGGAQIIDPHDAKIISEIQK
ECCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCCEEEEECCCCEEECCCHHHHHHHHHH
VSNIKHTLIKREGINKRIIIELKNEIDIKYIQKINDEFPNFNQKSKTTNLRIAYTPLHGT
HHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
GGTIIKKLFKGSKVELLTEQTQINPDPEFPTVKYPNPEEHTTMSRVIELAKKTNCDIAFA
CHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
TDPDADRLGIAFKENRKWKILNGNQIACILMHYLLSRENNPKNTFIIASFVTTPMLDKIA
CCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHH
QKFNTTLYRTYTGFKWIGNLIDKIQKKEPNKKFIFGCEESHGYLIGTGTRDKDAFSAIKG
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCHHHHHHHHH
FCDLMFTLKKNQITINQYLQTMYKEFGYYEDFTINKIFKETNGDFLREKLMLQFRNNITK
HHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EFAGLFIIKKLDYKTLKEIDMHGNIYTIKGYTHTTNAIKFLLENKIEITIRPSGTEAKIK
HHHHEEEEEECCHHHHHHHHCCCCEEEEECCEEHHHHHHHHCCCCEEEEEECCCCCEEEE
FYISIYSRYEQKNSIFDIMNKIKMEIEKY
EEEEEHHHHHHCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 2127799 [H]