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The map label for this gene is gcp

Identifier: 203284662

GI number: 203284662

Start: 825860

End: 826876

Strand: Reverse

Name: gcp

Synonym: BDU_773

Alternate gene names: 203284662

Gene position: 826876-825860 (Counterclockwise)

Preceding gene: 203284663

Following gene: 203284661

Centisome position: 88.75

GC content: 30.88

Gene sequence:

>1017_bases
ATGAAGGTACTTGGAATAGAAAGCTCATGTGATGATTGTTGTGCAGCTATAGTAGAAAATGGCAACACAATTTTAAGCAA
TATCAAACTTAGTCAAAAAGAACATAAAAAATATTATGGAATAGTACCAGAAATTGCCTCAAGACTACATACAGAATTTA
TTATGTATGTTTGTCAACAAGCCATAATAAGTGCTCAAATAAATATATCTGAAATAGATTTAATAGCAGTTACATCTCAA
CCTGGGCTTATTGGCTCTTTAATTGTTGGTGTAAACTTTGCCAAAGGACTGTCCATTGCCCTCAAAAAACCTCTAATTTG
TATTGATCACATTCTAGGACATCTTTATGCACCCTTGCTGAATCACACAATAGAATATCCATTTCTATCATTAGTATTAA
GTGGAGGTCACACAATACTTGCCAAACAAAATAATTTTGATGATATTGAAATACTTGGAAGAACACTCGATGATGCTTGT
GGAGAAGCATTTGACAAAATAGCAAAACATTATAAGATGGGATTTCCTGGTGGCCCAAATATAGAAAAATTGGCTATAGA
CGGAAATCAATATGCATTTAATTTTCCAATTACAATTTTTGACAAAAAAGAAAATAGATATGACTTCTCATATTCGGGCC
TCAAAACAGCATGCATACATCAACTTGAAAAATTTAAAAACAACAATGCCCAAATAACAAATAACAATATTGCTGCCAGT
TTTCAAAGAGCAGCTTTTGAAAATTTAATAATTCCAATAAAAAGAGCAATAAAGGATACTAACATAAAAAAATTAATAAT
ATCTGGAGGAGTAGCAAGCAACCTTTATTTAAGAGAAAAAATTAAAAACCTTGAAATAGAAACATACTATCCCCCAATCG
ACCTTTGTACAGACAACGCAGCAATGATTGCAGGAATTGGATATCTTATGTATTTAAAATATGGAGCAAGTTCCATTGAA
ACTAATGCAAACTCAAGAATAGAAAATTATAAATATACAAAAGGAGTAAAATTATGA

Upstream 100 bases:

>100_bases
TCAAAAAACACCCTTAAAATACTTCAACAAGAATCAGAAAACTTAAAGAAAGAATTTGTATTTAAAAATTTAATAAACCT
TTATCAAAGAGAGGAAAACA

Downstream 100 bases:

>100_bases
AACGAGTATTAGCCATGCATGATATTTCAACCATAGGTAAAGCATCACTTACAATATGCATACCAGTAATATCATCATTT
AATATTCAAGTTTGTCCACT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQAIISAQINISEIDLIAVTSQ
PGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLLNHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDAC
GEAFDKIAKHYKMGFPGGPNIEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAAS
FQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNAAMIAGIGYLMYLKYGASSIE
TNANSRIENYKYTKGVKL

Sequences:

>Translated_338_residues
MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQAIISAQINISEIDLIAVTSQ
PGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLLNHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDAC
GEAFDKIAKHYKMGFPGGPNIEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAAS
FQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNAAMIAGIGYLMYLKYGASSIE
TNANSRIENYKYTKGVKL
>Mature_338_residues
MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQAIISAQINISEIDLIAVTSQ
PGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLLNHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDAC
GEAFDKIAKHYKMGFPGGPNIEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAAS
FQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNAAMIAGIGYLMYLKYGASSIE
TNANSRIENYKYTKGVKL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=335, Percent_Identity=37.0149253731343, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI8923380, Length=317, Percent_Identity=26.813880126183, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789445, Length=324, Percent_Identity=39.8148148148148, Blast_Score=235, Evalue=4e-63,
Organism=Caenorhabditis elegans, GI17557464, Length=340, Percent_Identity=29.7058823529412, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71995670, Length=318, Percent_Identity=31.1320754716981, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=347, Percent_Identity=34.5821325648415, Blast_Score=169, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6322891, Length=303, Percent_Identity=27.7227722772277, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI20129063, Length=355, Percent_Identity=33.8028169014084, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI21357207, Length=324, Percent_Identity=27.1604938271605, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_BORDL (B5RMW0)

Other databases:

- EMBL:   CP000976
- RefSeq:   YP_002222402.1
- MEROPS:   M22.001
- EnsemblBacteria:   EBBORT00000001481
- GeneID:   6917999
- GenomeReviews:   CP000976_GR
- KEGG:   bdu:BDU_773
- GeneTree:   EBGT00050000006822
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37497; Mature: 37497

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQ
CEEECCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIISAQINISEIDLIAVTSQPGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLL
HHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
NHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDACGEAFDKIAKHYKMGFPGGPN
HHCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAAS
CEEEEECCCEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHH
FQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNA
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEECCCHHCCCCCH
AMIAGIGYLMYLKYGASSIETNANSRIENYKYTKGVKL
HHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVLGIESSCDDCCAAIVENGNTILSNIKLSQKEHKKYYGIVPEIASRLHTEFIMYVCQQ
CEEECCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
AIISAQINISEIDLIAVTSQPGLIGSLIVGVNFAKGLSIALKKPLICIDHILGHLYAPLL
HHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHH
NHTIEYPFLSLVLSGGHTILAKQNNFDDIEILGRTLDDACGEAFDKIAKHYKMGFPGGPN
HHCCCCHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEKLAIDGNQYAFNFPITIFDKKENRYDFSYSGLKTACIHQLEKFKNNNAQITNNNIAAS
CEEEEECCCEEEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHH
FQRAAFENLIIPIKRAIKDTNIKKLIISGGVASNLYLREKIKNLEIETYYPPIDLCTDNA
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCEEEEECCCHHCCCCCH
AMIAGIGYLMYLKYGASSIETNANSRIENYKYTKGVKL
HHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA