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The map label for this gene is barA [H]

Identifier: 203284330

GI number: 203284330

Start: 443576

End: 448021

Strand: Reverse

Name: barA [H]

Synonym: BDU_414

Alternate gene names: 203284330

Gene position: 448021-443576 (Counterclockwise)

Preceding gene: 203284331

Following gene: 203284329

Centisome position: 48.09

GC content: 25.51

Gene sequence:

>4446_bases
ATGCGCAATTTGAAAATTTTTTTATTTGTACTTTTTTTTTCTTATATTAGTTTGTCAGCCAAACAAACTCTAAAATTTAA
GCTTGTAGATCAATATTATCCTTTATATTACAAAAATAAAGAAGGTAAGATGACTGGTATGATTTTTTATCTTCTTAACA
AATGGGCACAGGATCATCATTATGAAATTAGTGTAGAGGCCATTGATTATCTTGATCAAAGCAAAATAGAAGATGATGTG
GTTTATTTGGGATTAACATATAATTCTGATTTAAGTGAACATCTGTATTTTAAAAATGAAATTGGCAAATGTGTAACGGC
ATTGGTTTATAATTCAAAGGAAAATCAAAAAATTACAAATCCATCTCTTTCAAAAGAATTTCGTGTAGGAGTTGTAAAAA
ATAGCATATATAAAGATATTTTGAAGTTGCATGGTCATATTGATAATGTTTTTTCATTTTCAGATACACAACAGTTATTT
TCAGCATTAAGAGATAACAAAATTGATTTAATATATGGAAGTTACAAATCATTGTATTTTTTATGGCATATTTATTTTGA
TCCATCTTTTTTAAAAGTATTTAATTCTGACTATTTTTATAGTTTTGGCATACGGGTTGCTATTAGTAAAAAAGCTGTTA
ATGAACTGAAGAGTTTAGATATTGATCTCTTGAGTTATATGAAAGCTCTCTCTAAAAGCGAATATGCTTCTTTTAAGGAG
TTAGATTACTTATTTAATCTTGATGTTGGAATATATAATGATTATCCTCCTTTAAGTTTTATTAATTCTAAAGGTCAATT
ATCAGGAATTTTAGTTGATTTATGGAATGATCTCTCTAGAGAATATGCTTTTTCTTTAAAATTTGTAGGATTTCCAAAGG
AAAGTATTAAACTGAGTCTGGATGATAAAGATATATCTGTTTGGGGTGGTATTATTGAAGATAATAATATTTTGACTTCA
AAAATCTATAAAGTAACAGATCCAATATGTATGCTTGATTTTAATTTTTACTTAACGAATTCTAGAAATAGTGATAAAAT
CTTAAATTCACAAATTGTTGATTTTCACTTAAGTGGTATAAGGTTAGATAAAAATACAGACATAGTTAATAATTTTGCAG
ATATAATAAATAATTCATATGGTTTTATAGAAAATTCAATTACTACAAATTATCTATTGAGGTTGCATGGGTATAATAAT
ATATTAAAATTTAAAGATTTAAGTTTTAACGTGCAAAAACCTTTAATATTAGCTAGTAATATTCGCAAATTGCAGTTGTT
CTCGTATATGCTAGATGCATTAACATCAAATATCTTATTTGATACTTTATTAGAGATAGATAAAAATTGGTTTACTCAAA
ATGAGATTGAAGATTATCAAAGTAGTTGTTATAGCCATGTAAATAGCAGTAATTTTAATATTGAAGAAAAAATTTGGTTG
GAGCACAATAAAAAATTAAATCTTGCTGTTAAGAATTGGTATCCTGTTGATTATGTAAATTCTGGTCGTTATAAGGGAAT
AAATGAATGGTTAATTAAAAAGATAAAAAGATTAACAAATGTGGATTTTAATATTATTAATGTACGTGAGCGGGAACTCA
AAGATTTAATTAAGAATGGTCAAATAGATATTTTGTCTTCTAATTTGGATAGTGCAAATTTAGATTATTTTTTTAATATT
AAATCAGTTTCAGGAATTCCTTTATATATTTTTTCACAAAAAACTAATTTATTTATTCCCAAATCATCTGATCGTATAGC
AGTGCTTAACTTTTTATATTCTAATAAATTGGAAACCCAAATAGGAGCACAATTAGTACAAGTAGAGAGTTTTAAAGAGG
CTTTGGATTTGATATACAAGAGAGAAGTTGATGGAATTCTTAGTGATGAGTATACTGCTACTGTTAATTTTGAAGATTTA
AATGTTAGAGATCTTGAAAAAATTGTTAATGTGTCGGATTTATCATTTAATTTGAATATTGCTGTTTATAATCAAGATTA
TATTTTAAGAAGAATTATACAAAAAATTTTATTCCGAACAAATGTTAATAATAAATTATATTTTGATGATTGGGTATTTA
ATGTTCATGAAAGTTCTAAAGACATGAAATTAAAAAAATCTGGTATATTAGTCTTAGCGATTGTTTTTTTTGTTTTAACT
ATTTTAATGTTTTTCTTATTCAGATTATTGAAAGAAATAGGATTTAGAAAAAAAATGTATTCTTCTGTAATTAGTGAAAA
AAAAGTTATTGAAGATGCTATTGTTGCTAAGACTATTTTTTTAGCAAGTATGAGTCATGACATTCGTACTCCCATTAATG
GCATAATAGCAGCTACCGAACTTCTAGATAATACAGATCTTTTAGGTGTTCAAAAAGAATATGTGCAAATGATCAATTAT
TCATCTACTTCATTACTTTCTTTGATTGATGAAATATTGTATATCTCTAAAATAGATATGAATGGTATATATATTGAAAA
TAATGAAATAAATCTAGAATATGAGATTGAAGAAGTTGTAAAAAGTTTTCAGTCTCAAAGCGCAAAACATAATCTTGATT
TAATTTTTTATTCAAAATCAGATTTAAATAATTATTTGATAGGAGATAGGTCTAGACTTAAGAAAGTACTTATTAATTTG
ATAAGCAATGCTTTTAAGTTTACTAAGGAAGGAATCATAATTATAAACTATGAAATTATATGTACTAGAGAAGGTGATAA
TGGTGATAGAATTTTTACCATTGAATTTAAAGTAATTGATACTGGTAAAGGAATTAAAAAAGGAAATATACCCGTAATAT
TTGAATTATTCAAACAGGGAGATGACTTTGATGCAAAAGAATATGAAGGAACGGGACTTGGACTTGCAATATCTAGAAAG
CTTGTCAGTTTAATGGGTGGTCCTGGTATTACTGTTGAGAGTGAGGTGGGCAAAGGGACAACTTTTTCATTTATGTTGCC
TTTTGTTTTAGGTAATGAGATTAATGATAAAGAGAAAAGTAAATTTAAATTGATTAGGAATAAAAAGATTTTAACTTTAT
TTTCAAGTAATAAAGCTGTTGTCTTGTTAAATGAAATAAGTGAAATCCTTGATTATAAGGATAACGTACGTAATTTTTAT
TCTTATGAGGATGCTTATGAAGAATGTTCTAAATATCCTTATTATGATTTTATTTTTATAAATGTTGATAATGCGGATTT
ACAAAAGTGTTTAAAATTTGCTGAACGGCTTGAAAAATTAAATTTAGATGCAAAAATAGTATTTGTGTTCTATTATTTAA
AGAATGAAGAGATCATTGATTTTAAATACGAATATATTCAAAAACCTTTTAAAAGGTGGGATTTTTATTCTGATTGGATT
ATAAATGGTTCACTTGTAGATGCTCCATTAATTGATGATTCTGGAATTTTCAAGCTTAAGGATAATATTTGTATATTGAT
AGCCGAAGATAATGAGATTAATCAAAAAATTTTAAAAAATATTTTGATTGTTATAGGCGTTAGAGAAGATTCTATTGATA
TTGTGGATGATGGTTTTAAGGCCATTGATTATTTAAAAACCAATAGATATGATATTGCTTTTGTTGACATAAGAATGCCA
AAATGTGATGGATTTACAGTATCTGAAGAAATACGAAGATATGAAAAACAAAATAATTTAAATTCATGTGTGTTAATAGC
TGTTACTGCACATGCTTTAAGGGAATATAAAGATAGGTGTTTGGAGAGTGGAATGAATGATTATCTTGCAAAACCCATAC
ATATTAAGTCGATTAAATATATATTAAAAAAATATTTATATATTGATGAGGTTAAGAATAATAATATTATAGAATATAAA
AATTTCGATAAATTGGATGATTTGGATATTAATCGTGCTTTGCAAGATTTGGATATTTCGTATGACATGTACATTGATTT
ATGTAGAGGTTTTGTTGTCATGAGTGATAATATTATACGTGATTTGGATGAGGCATTTAATTTAAATAATGTGGTATTAA
TAAAAGAGTTGGCACATTCAATAGCAGGTGCTCTTGGTAATATGCGTAGTAATTTATTTGATGATTTTAAACAAATTGAA
AATGGTACAGATTCAATAGAGGAATTAAGAGTACTATATTCTAAAGCACGTCAAAATTTGATTATGCTTGTTAAAAATAT
AAGAGATCGGATATTAAATGTTGTTGATATTGATGATTATGAAAAATTAGAATTTCAAAGTAATAATGACTTTTTAATTA
TTATGCAAAAACTTTTAAATGAGATAGAAAATAGAAATCCAAAAGAATATAAAAAAATTCTTGAAACCCTTAAAAAATAT
CATTGGGATGATGATAATATTGTGTTATTTGATTCTCTTGTTGAATGTTTAAGGGTATATAATTTTAAGGAAAGTGTTAA
CATTATCAAACGTATGATGAGCCATAATAGAATAGGGAAATTGTGA

Upstream 100 bases:

>100_bases
GATGGTACTGCGAGTTCGCGGGAGAGTAAGTTATTGCCAGGGTTTTTTTCGTTTTATTGTACTGTTAGTGTTTATTTTAA
AACATGTAAGTAGCATAATT

Downstream 100 bases:

>100_bases
TGAAAGGTATAATTTTAGATAACTTTGATGAAATTGCGATTGAACCTCAAAAGTTATTACTTGTAGATGATACGCCTACA
AATTTAGATTTGTTACTAGA

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1481; Mature: 1481

Protein sequence:

>1481_residues
MRNLKIFLFVLFFSYISLSAKQTLKFKLVDQYYPLYYKNKEGKMTGMIFYLLNKWAQDHHYEISVEAIDYLDQSKIEDDV
VYLGLTYNSDLSEHLYFKNEIGKCVTALVYNSKENQKITNPSLSKEFRVGVVKNSIYKDILKLHGHIDNVFSFSDTQQLF
SALRDNKIDLIYGSYKSLYFLWHIYFDPSFLKVFNSDYFYSFGIRVAISKKAVNELKSLDIDLLSYMKALSKSEYASFKE
LDYLFNLDVGIYNDYPPLSFINSKGQLSGILVDLWNDLSREYAFSLKFVGFPKESIKLSLDDKDISVWGGIIEDNNILTS
KIYKVTDPICMLDFNFYLTNSRNSDKILNSQIVDFHLSGIRLDKNTDIVNNFADIINNSYGFIENSITTNYLLRLHGYNN
ILKFKDLSFNVQKPLILASNIRKLQLFSYMLDALTSNILFDTLLEIDKNWFTQNEIEDYQSSCYSHVNSSNFNIEEKIWL
EHNKKLNLAVKNWYPVDYVNSGRYKGINEWLIKKIKRLTNVDFNIINVRERELKDLIKNGQIDILSSNLDSANLDYFFNI
KSVSGIPLYIFSQKTNLFIPKSSDRIAVLNFLYSNKLETQIGAQLVQVESFKEALDLIYKREVDGILSDEYTATVNFEDL
NVRDLEKIVNVSDLSFNLNIAVYNQDYILRRIIQKILFRTNVNNKLYFDDWVFNVHESSKDMKLKKSGILVLAIVFFVLT
ILMFFLFRLLKEIGFRKKMYSSVISEKKVIEDAIVAKTIFLASMSHDIRTPINGIIAATELLDNTDLLGVQKEYVQMINY
SSTSLLSLIDEILYISKIDMNGIYIENNEINLEYEIEEVVKSFQSQSAKHNLDLIFYSKSDLNNYLIGDRSRLKKVLINL
ISNAFKFTKEGIIIINYEIICTREGDNGDRIFTIEFKVIDTGKGIKKGNIPVIFELFKQGDDFDAKEYEGTGLGLAISRK
LVSLMGGPGITVESEVGKGTTFSFMLPFVLGNEINDKEKSKFKLIRNKKILTLFSSNKAVVLLNEISEILDYKDNVRNFY
SYEDAYEECSKYPYYDFIFINVDNADLQKCLKFAERLEKLNLDAKIVFVFYYLKNEEIIDFKYEYIQKPFKRWDFYSDWI
INGSLVDAPLIDDSGIFKLKDNICILIAEDNEINQKILKNILIVIGVREDSIDIVDDGFKAIDYLKTNRYDIAFVDIRMP
KCDGFTVSEEIRRYEKQNNLNSCVLIAVTAHALREYKDRCLESGMNDYLAKPIHIKSIKYILKKYLYIDEVKNNNIIEYK
NFDKLDDLDINRALQDLDISYDMYIDLCRGFVVMSDNIIRDLDEAFNLNNVVLIKELAHSIAGALGNMRSNLFDDFKQIE
NGTDSIEELRVLYSKARQNLIMLVKNIRDRILNVVDIDDYEKLEFQSNNDFLIIMQKLLNEIENRNPKEYKKILETLKKY
HWDDDNIVLFDSLVECLRVYNFKESVNIIKRMMSHNRIGKL

Sequences:

>Translated_1481_residues
MRNLKIFLFVLFFSYISLSAKQTLKFKLVDQYYPLYYKNKEGKMTGMIFYLLNKWAQDHHYEISVEAIDYLDQSKIEDDV
VYLGLTYNSDLSEHLYFKNEIGKCVTALVYNSKENQKITNPSLSKEFRVGVVKNSIYKDILKLHGHIDNVFSFSDTQQLF
SALRDNKIDLIYGSYKSLYFLWHIYFDPSFLKVFNSDYFYSFGIRVAISKKAVNELKSLDIDLLSYMKALSKSEYASFKE
LDYLFNLDVGIYNDYPPLSFINSKGQLSGILVDLWNDLSREYAFSLKFVGFPKESIKLSLDDKDISVWGGIIEDNNILTS
KIYKVTDPICMLDFNFYLTNSRNSDKILNSQIVDFHLSGIRLDKNTDIVNNFADIINNSYGFIENSITTNYLLRLHGYNN
ILKFKDLSFNVQKPLILASNIRKLQLFSYMLDALTSNILFDTLLEIDKNWFTQNEIEDYQSSCYSHVNSSNFNIEEKIWL
EHNKKLNLAVKNWYPVDYVNSGRYKGINEWLIKKIKRLTNVDFNIINVRERELKDLIKNGQIDILSSNLDSANLDYFFNI
KSVSGIPLYIFSQKTNLFIPKSSDRIAVLNFLYSNKLETQIGAQLVQVESFKEALDLIYKREVDGILSDEYTATVNFEDL
NVRDLEKIVNVSDLSFNLNIAVYNQDYILRRIIQKILFRTNVNNKLYFDDWVFNVHESSKDMKLKKSGILVLAIVFFVLT
ILMFFLFRLLKEIGFRKKMYSSVISEKKVIEDAIVAKTIFLASMSHDIRTPINGIIAATELLDNTDLLGVQKEYVQMINY
SSTSLLSLIDEILYISKIDMNGIYIENNEINLEYEIEEVVKSFQSQSAKHNLDLIFYSKSDLNNYLIGDRSRLKKVLINL
ISNAFKFTKEGIIIINYEIICTREGDNGDRIFTIEFKVIDTGKGIKKGNIPVIFELFKQGDDFDAKEYEGTGLGLAISRK
LVSLMGGPGITVESEVGKGTTFSFMLPFVLGNEINDKEKSKFKLIRNKKILTLFSSNKAVVLLNEISEILDYKDNVRNFY
SYEDAYEECSKYPYYDFIFINVDNADLQKCLKFAERLEKLNLDAKIVFVFYYLKNEEIIDFKYEYIQKPFKRWDFYSDWI
INGSLVDAPLIDDSGIFKLKDNICILIAEDNEINQKILKNILIVIGVREDSIDIVDDGFKAIDYLKTNRYDIAFVDIRMP
KCDGFTVSEEIRRYEKQNNLNSCVLIAVTAHALREYKDRCLESGMNDYLAKPIHIKSIKYILKKYLYIDEVKNNNIIEYK
NFDKLDDLDINRALQDLDISYDMYIDLCRGFVVMSDNIIRDLDEAFNLNNVVLIKELAHSIAGALGNMRSNLFDDFKQIE
NGTDSIEELRVLYSKARQNLIMLVKNIRDRILNVVDIDDYEKLEFQSNNDFLIIMQKLLNEIENRNPKEYKKILETLKKY
HWDDDNIVLFDSLVECLRVYNFKESVNIIKRMMSHNRIGKL
>Mature_1481_residues
MRNLKIFLFVLFFSYISLSAKQTLKFKLVDQYYPLYYKNKEGKMTGMIFYLLNKWAQDHHYEISVEAIDYLDQSKIEDDV
VYLGLTYNSDLSEHLYFKNEIGKCVTALVYNSKENQKITNPSLSKEFRVGVVKNSIYKDILKLHGHIDNVFSFSDTQQLF
SALRDNKIDLIYGSYKSLYFLWHIYFDPSFLKVFNSDYFYSFGIRVAISKKAVNELKSLDIDLLSYMKALSKSEYASFKE
LDYLFNLDVGIYNDYPPLSFINSKGQLSGILVDLWNDLSREYAFSLKFVGFPKESIKLSLDDKDISVWGGIIEDNNILTS
KIYKVTDPICMLDFNFYLTNSRNSDKILNSQIVDFHLSGIRLDKNTDIVNNFADIINNSYGFIENSITTNYLLRLHGYNN
ILKFKDLSFNVQKPLILASNIRKLQLFSYMLDALTSNILFDTLLEIDKNWFTQNEIEDYQSSCYSHVNSSNFNIEEKIWL
EHNKKLNLAVKNWYPVDYVNSGRYKGINEWLIKKIKRLTNVDFNIINVRERELKDLIKNGQIDILSSNLDSANLDYFFNI
KSVSGIPLYIFSQKTNLFIPKSSDRIAVLNFLYSNKLETQIGAQLVQVESFKEALDLIYKREVDGILSDEYTATVNFEDL
NVRDLEKIVNVSDLSFNLNIAVYNQDYILRRIIQKILFRTNVNNKLYFDDWVFNVHESSKDMKLKKSGILVLAIVFFVLT
ILMFFLFRLLKEIGFRKKMYSSVISEKKVIEDAIVAKTIFLASMSHDIRTPINGIIAATELLDNTDLLGVQKEYVQMINY
SSTSLLSLIDEILYISKIDMNGIYIENNEINLEYEIEEVVKSFQSQSAKHNLDLIFYSKSDLNNYLIGDRSRLKKVLINL
ISNAFKFTKEGIIIINYEIICTREGDNGDRIFTIEFKVIDTGKGIKKGNIPVIFELFKQGDDFDAKEYEGTGLGLAISRK
LVSLMGGPGITVESEVGKGTTFSFMLPFVLGNEINDKEKSKFKLIRNKKILTLFSSNKAVVLLNEISEILDYKDNVRNFY
SYEDAYEECSKYPYYDFIFINVDNADLQKCLKFAERLEKLNLDAKIVFVFYYLKNEEIIDFKYEYIQKPFKRWDFYSDWI
INGSLVDAPLIDDSGIFKLKDNICILIAEDNEINQKILKNILIVIGVREDSIDIVDDGFKAIDYLKTNRYDIAFVDIRMP
KCDGFTVSEEIRRYEKQNNLNSCVLIAVTAHALREYKDRCLESGMNDYLAKPIHIKSIKYILKKYLYIDEVKNNNIIEYK
NFDKLDDLDINRALQDLDISYDMYIDLCRGFVVMSDNIIRDLDEAFNLNNVVLIKELAHSIAGALGNMRSNLFDDFKQIE
NGTDSIEELRVLYSKARQNLIMLVKNIRDRILNVVDIDDYEKLEFQSNNDFLIIMQKLLNEIENRNPKEYKKILETLKKY
HWDDDNIVLFDSLVECLRVYNFKESVNIIKRMMSHNRIGKL

Specific function: Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system. Phosphorylates UvrY, probably via a four-step phosphorelay [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=534, Percent_Identity=29.0262172284644, Blast_Score=201, Evalue=4e-52,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=33.8461538461538, Blast_Score=137, Evalue=7e-33,
Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=32.6923076923077, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1788713, Length=255, Percent_Identity=32.5490196078431, Blast_Score=121, Evalue=3e-28,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=32.0833333333333, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=28.2051282051282, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=27.0833333333333, Blast_Score=83, Evalue=1e-16,
Organism=Escherichia coli, GI87082128, Length=307, Percent_Identity=27.6872964169381, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=26.4367816091954, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=25, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1790436, Length=278, Percent_Identity=25.8992805755396, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=27.0386266094421, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=400, Percent_Identity=28.25, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322000, Length=128, Percent_Identity=31.25, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR019247
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF09984 DUF2222; PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 172643; Mature: 172643

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLKIFLFVLFFSYISLSAKQTLKFKLVDQYYPLYYKNKEGKMTGMIFYLLNKWAQDHH
CCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
YEISVEAIDYLDQSKIEDDVVYLGLTYNSDLSEHLYFKNEIGKCVTALVYNSKENQKITN
EEEEEHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSLSKEFRVGVVKNSIYKDILKLHGHIDNVFSFSDTQQLFSALRDNKIDLIYGSYKSLYF
CCCCHHHEEEHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEE
LWHIYFDPSFLKVFNSDYFYSFGIRVAISKKAVNELKSLDIDLLSYMKALSKSEYASFKE
EEEEEECCHHHHHHCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
LDYLFNLDVGIYNDYPPLSFINSKGQLSGILVDLWNDLSREYAFSLKFVGFPKESIKLSL
HHEEEECCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHEEEEE
DDKDISVWGGIIEDNNILTSKIYKVTDPICMLDFNFYLTNSRNSDKILNSQIVDFHLSGI
CCCCEEEECCEEECCCEEHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHCCEEEEEECCE
RLDKNTDIVNNFADIINNSYGFIENSITTNYLLRLHGYNNILKFKDLSFNVQKPLILASN
EECCCCHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCEEEEECCCCCCCCCEEECCC
IRKLQLFSYMLDALTSNILFDTLLEIDKNWFTQNEIEDYQSSCYSHVNSSNFNIEEKIWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
EHNKKLNLAVKNWYPVDYVNSGRYKGINEWLIKKIKRLTNVDFNIINVRERELKDLIKNG
ECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC
QIDILSSNLDSANLDYFFNIKSVSGIPLYIFSQKTNLFIPKSSDRIAVLNFLYSNKLETQ
CEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCEEEEEHHHCCCHHHH
IGAQLVQVESFKEALDLIYKREVDGILSDEYTATVNFEDLNVRDLEKIVNVSDLSFNLNI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEE
AVYNQDYILRRIIQKILFRTNVNNKLYFDDWVFNVHESSKDMKLKKSGILVLAIVFFVLT
EEECCCHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCEEHHCCHHHHHHHHHHHH
ILMFFLFRLLKEIGFRKKMYSSVISEKKVIEDAIVAKTIFLASMSHDIRTPINGIIAATE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLDNTDLLGVQKEYVQMINYSSTSLLSLIDEILYISKIDMNGIYIENNEINLEYEIEEVV
HHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCEEEECCEEEEEEEHHHHH
KSFQSQSAKHNLDLIFYSKSDLNNYLIGDRSRLKKVLINLISNAFKFTKEGIIIINYEII
HHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
CTREGDNGDRIFTIEFKVIDTGKGIKKGNIPVIFELFKQGDDFDAKEYEGTGLGLAISRK
EEECCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LVSLMGGPGITVESEVGKGTTFSFMLPFVLGNEINDKEKSKFKLIRNKKILTLFSSNKAV
HHHHHCCCCCEEECCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCEE
VLLNEISEILDYKDNVRNFYSYEDAYEECSKYPYYDFIFINVDNADLQKCLKFAERLEKL
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHC
NLDAKIVFVFYYLKNEEIIDFKYEYIQKPFKRWDFYSDWIINGSLVDAPLIDDSGIFKLK
CCCEEEEEEEEEECCCCEEEEEHHHHHHHHHHCCCCCCEEECCCEEECCEECCCCEEEEE
DNICILIAEDNEINQKILKNILIVIGVREDSIDIVDDGFKAIDYLKTNRYDIAFVDIRMP
CCEEEEEECCCCHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEEEECC
KCDGFTVSEEIRRYEKQNNLNSCVLIAVTAHALREYKDRCLESGMNDYLAKPIHIKSIKY
CCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHCCCEEHHHHHH
ILKKYLYIDEVKNNNIIEYKNFDKLDDLDINRALQDLDISYDMYIDLCRGFVVMSDNIIR
HHHHHHHHEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEECCHHHH
DLDEAFNLNNVVLIKELAHSIAGALGNMRSNLFDDFKQIENGTDSIEELRVLYSKARQNL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IMLVKNIRDRILNVVDIDDYEKLEFQSNNDFLIIMQKLLNEIENRNPKEYKKILETLKKY
HHHHHHHHHHHCEEECCCCCHHEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHH
HWDDDNIVLFDSLVECLRVYNFKESVNIIKRMMSHNRIGKL
CCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRNLKIFLFVLFFSYISLSAKQTLKFKLVDQYYPLYYKNKEGKMTGMIFYLLNKWAQDHH
CCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHCCCCC
YEISVEAIDYLDQSKIEDDVVYLGLTYNSDLSEHLYFKNEIGKCVTALVYNSKENQKITN
EEEEEHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSLSKEFRVGVVKNSIYKDILKLHGHIDNVFSFSDTQQLFSALRDNKIDLIYGSYKSLYF
CCCCHHHEEEHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHCCCCEEEEECCCCEEEE
LWHIYFDPSFLKVFNSDYFYSFGIRVAISKKAVNELKSLDIDLLSYMKALSKSEYASFKE
EEEEEECCHHHHHHCCCEEEEEEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
LDYLFNLDVGIYNDYPPLSFINSKGQLSGILVDLWNDLSREYAFSLKFVGFPKESIKLSL
HHEEEECCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHHHEEEEEEECCCCHHEEEEE
DDKDISVWGGIIEDNNILTSKIYKVTDPICMLDFNFYLTNSRNSDKILNSQIVDFHLSGI
CCCCEEEECCEEECCCEEHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHCCEEEEEECCE
RLDKNTDIVNNFADIINNSYGFIENSITTNYLLRLHGYNNILKFKDLSFNVQKPLILASN
EECCCCHHHHHHHHHHCCCCCCEECCCCEEEEEEECCCCCEEEEECCCCCCCCCEEECCC
IRKLQLFSYMLDALTSNILFDTLLEIDKNWFTQNEIEDYQSSCYSHVNSSNFNIEEKIWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
EHNKKLNLAVKNWYPVDYVNSGRYKGINEWLIKKIKRLTNVDFNIINVRERELKDLIKNG
ECCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHCC
QIDILSSNLDSANLDYFFNIKSVSGIPLYIFSQKTNLFIPKSSDRIAVLNFLYSNKLETQ
CEEEEECCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEECCCCCEEEEEHHHCCCHHHH
IGAQLVQVESFKEALDLIYKREVDGILSDEYTATVNFEDLNVRDLEKIVNVSDLSFNLNI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEEEEE
AVYNQDYILRRIIQKILFRTNVNNKLYFDDWVFNVHESSKDMKLKKSGILVLAIVFFVLT
EEECCCHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCEEHHCCHHHHHHHHHHHH
ILMFFLFRLLKEIGFRKKMYSSVISEKKVIEDAIVAKTIFLASMSHDIRTPINGIIAATE
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLDNTDLLGVQKEYVQMINYSSTSLLSLIDEILYISKIDMNGIYIENNEINLEYEIEEVV
HHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCEEEECCEEEEEEEHHHHH
KSFQSQSAKHNLDLIFYSKSDLNNYLIGDRSRLKKVLINLISNAFKFTKEGIIIINYEII
HHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEE
CTREGDNGDRIFTIEFKVIDTGKGIKKGNIPVIFELFKQGDDFDAKEYEGTGLGLAISRK
EEECCCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHH
LVSLMGGPGITVESEVGKGTTFSFMLPFVLGNEINDKEKSKFKLIRNKKILTLFSSNKAV
HHHHHCCCCCEEECCCCCCCCCEEEEHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCCEE
VLLNEISEILDYKDNVRNFYSYEDAYEECSKYPYYDFIFINVDNADLQKCLKFAERLEKL
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHHHC
NLDAKIVFVFYYLKNEEIIDFKYEYIQKPFKRWDFYSDWIINGSLVDAPLIDDSGIFKLK
CCCEEEEEEEEEECCCCEEEEEHHHHHHHHHHCCCCCCEEECCCEEECCEECCCCEEEEE
DNICILIAEDNEINQKILKNILIVIGVREDSIDIVDDGFKAIDYLKTNRYDIAFVDIRMP
CCEEEEEECCCCHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEEEECC
KCDGFTVSEEIRRYEKQNNLNSCVLIAVTAHALREYKDRCLESGMNDYLAKPIHIKSIKY
CCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHCCCEEHHHHHH
ILKKYLYIDEVKNNNIIEYKNFDKLDDLDINRALQDLDISYDMYIDLCRGFVVMSDNIIR
HHHHHHHHEECCCCCEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEECCHHHH
DLDEAFNLNNVVLIKELAHSIAGALGNMRSNLFDDFKQIENGTDSIEELRVLYSKARQNL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
IMLVKNIRDRILNVVDIDDYEKLEFQSNNDFLIIMQKLLNEIENRNPKEYKKILETLKKY
HHHHHHHHHHHCEEECCCCCHHEEECCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHH
HWDDDNIVLFDSLVECLRVYNFKESVNIIKRMMSHNRIGKL
CCCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]