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The map label for this gene is malX [H]

Identifier: 203284041

GI number: 203284041

Start: 124529

End: 126235

Strand: Reverse

Name: malX [H]

Synonym: BDU_119

Alternate gene names: 203284041

Gene position: 126235-124529 (Counterclockwise)

Preceding gene: 203284043

Following gene: 203284040

Centisome position: 13.55

GC content: 29.58

Gene sequence:

>1707_bases
ATGGAGAGGTTCAGCGTGATAGGTTTTTTAAAAATTTTGAAATTTGCTAATTTGCAAAAGTTTTCTAGTGCAGTGAGATT
GCCAATTTCTGTTACTACGATTTTTTCTTTGATGCTGGGTATAGGGTCAGCATTTTTAAATCCTTCTAATTTATTTTATA
TTGATAATGCTGTTTTTAAATTGATTTTGGGTCTTATTAAAAGTATAAGCAATATTGTTATATTAAATATTCCTTTATTT
TTTGTTATAGGTATTGCTGTTGTTGTTGCTAGAGTTCAAAAAGGTACTGCTGCGCTTTTAGGTCTTGTTGGATATTTAAT
TTTTAACGTTACTGAAAATTATTTTCTTGGGGTATTTTCAGGATTAGCTGAATCTGATTTGATGTCTTCTGTTGGACAAG
TTAAAGTTTTAGGAATCCAAACTTTAAACACAGGTATTTTGGGTGGTTTATCGGTTGGGCTTTTAGTTGGTTATTTACAT
AATAGATTTTGTAATATTGAATTACCAGGACCTTTTGATATTTTTTCTGGAATTAGATTTGTTTCTATGGTAATTTTTCC
TTTTTGTATTTTATTGGGAGTATTATTTTTTTTAATTTGGCCTTATTTTAATGAACTTATCACTTCTTTTGGATTTTTTA
TTGCTAAGTTAGATTATTATGGTAGTTTTTTTTATGGATTTTTAAACAGAATACTCATTCCTTTAGGACTTCATTCTATT
TTGACATTCCCTTTTAATTTTACTTCTTTGGGAGGATCTGAAATAATTAATGATCAGGTTGTTGGTGGTATTCAGAATAT
ATTTTATGCTCAATTGTCAGATCCATATCTTACAAAATTTTCTTCAAGTATTTCTAGATTCAATAGTGGATTTTATCTTT
CTATTATGTTTGGACTTCCTGGGGCAGCATTTGGAGTTTATAGAGGGATTATTCATGATGATAAGCGTAAGATCTTAGCA
TTGTTATTTCCAGGGGCTTTTGCAGCTTTTTTTACTGGCATTACAGAACCTTTAGAGTTTTTATTTGTTTTTACAGCTCC
TTTGCTTTATTTTGTGCATGCTATTTATACTGGATTTGCATTGTTAATTGCTAATATACTTGATATTTCAGTTGGTATGA
CTTTTTCTGCTGGATTTTTGGATTTTGTTATGTTTGGGATATTACAAGGGCATGATAAGACAAATTGGCTCTATTTGTTA
CCATTAGGTTTGTTATTTTTTGCTTTGTATTATTTTACTTTTAAATGGGTTTATAATTATTTTGATTTTCAAATTCTTGG
TGTTGGAGAGCCGTTTTTTGCTGGAAGTGAAGGTGAAGTTGAAGGGATGGGGATTGCTCATTTAATAGTTCAAGGACTTG
GAGGTCTTGATAATATTCAAGAATTTGGTGTTGTATCGACAAATTTAAACTTTGTGGTTTTCAGTCCAGAACTTAGGTTT
GAAGATTTTCTTAAAAAAACAGGTGCTTTGAATATTGTTACAGTTGGTAATACAATTCAAATTGATTATGGAACAAATGT
TTATTATATAAAACAGGCTATTGAAAACTATTCTTCCAAAAGTTTGTTTAAAGCCAGTGTTATTGTTGCATCTGAGAATA
TAAGACAAGGAATTAAAGCATATATTGATATGAAAGAAGATGATAAGCGTGAAAAACAAGGAGCAACAGGGAAGCTTTAT
AAGCTTAATAAAGATGATAGAGATTAA

Upstream 100 bases:

>100_bases
TGGAACTAGAGATTATGTTAATTTTCTTATTAAATTTTTATATTAAAATCTAACTTTTTCTAAAAAAAGCAATATAATGT
TGAATTGTCTTAATTTTTAG

Downstream 100 bases:

>100_bases
ACTTGAGAGTATAATAAAAATTATAGATTTATAACTACTAAATAGTAAATTATTTTTTATGATTGATTTAAGTATCTTTT
TGAAGGAATGAAAATTTAAA

Product: PTS system, maltose and glucose-specific IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 568; Mature: 568

Protein sequence:

>568_residues
MERFSVIGFLKILKFANLQKFSSAVRLPISVTTIFSLMLGIGSAFLNPSNLFYIDNAVFKLILGLIKSISNIVILNIPLF
FVIGIAVVVARVQKGTAALLGLVGYLIFNVTENYFLGVFSGLAESDLMSSVGQVKVLGIQTLNTGILGGLSVGLLVGYLH
NRFCNIELPGPFDIFSGIRFVSMVIFPFCILLGVLFFLIWPYFNELITSFGFFIAKLDYYGSFFYGFLNRILIPLGLHSI
LTFPFNFTSLGGSEIINDQVVGGIQNIFYAQLSDPYLTKFSSSISRFNSGFYLSIMFGLPGAAFGVYRGIIHDDKRKILA
LLFPGAFAAFFTGITEPLEFLFVFTAPLLYFVHAIYTGFALLIANILDISVGMTFSAGFLDFVMFGILQGHDKTNWLYLL
PLGLLFFALYYFTFKWVYNYFDFQILGVGEPFFAGSEGEVEGMGIAHLIVQGLGGLDNIQEFGVVSTNLNFVVFSPELRF
EDFLKKTGALNIVTVGNTIQIDYGTNVYYIKQAIENYSSKSLFKASVIVASENIRQGIKAYIDMKEDDKREKQGATGKLY
KLNKDDRD

Sequences:

>Translated_568_residues
MERFSVIGFLKILKFANLQKFSSAVRLPISVTTIFSLMLGIGSAFLNPSNLFYIDNAVFKLILGLIKSISNIVILNIPLF
FVIGIAVVVARVQKGTAALLGLVGYLIFNVTENYFLGVFSGLAESDLMSSVGQVKVLGIQTLNTGILGGLSVGLLVGYLH
NRFCNIELPGPFDIFSGIRFVSMVIFPFCILLGVLFFLIWPYFNELITSFGFFIAKLDYYGSFFYGFLNRILIPLGLHSI
LTFPFNFTSLGGSEIINDQVVGGIQNIFYAQLSDPYLTKFSSSISRFNSGFYLSIMFGLPGAAFGVYRGIIHDDKRKILA
LLFPGAFAAFFTGITEPLEFLFVFTAPLLYFVHAIYTGFALLIANILDISVGMTFSAGFLDFVMFGILQGHDKTNWLYLL
PLGLLFFALYYFTFKWVYNYFDFQILGVGEPFFAGSEGEVEGMGIAHLIVQGLGGLDNIQEFGVVSTNLNFVVFSPELRF
EDFLKKTGALNIVTVGNTIQIDYGTNVYYIKQAIENYSSKSLFKASVIVASENIRQGIKAYIDMKEDDKREKQGATGKLY
KLNKDDRD
>Mature_568_residues
MERFSVIGFLKILKFANLQKFSSAVRLPISVTTIFSLMLGIGSAFLNPSNLFYIDNAVFKLILGLIKSISNIVILNIPLF
FVIGIAVVVARVQKGTAALLGLVGYLIFNVTENYFLGVFSGLAESDLMSSVGQVKVLGIQTLNTGILGGLSVGLLVGYLH
NRFCNIELPGPFDIFSGIRFVSMVIFPFCILLGVLFFLIWPYFNELITSFGFFIAKLDYYGSFFYGFLNRILIPLGLHSI
LTFPFNFTSLGGSEIINDQVVGGIQNIFYAQLSDPYLTKFSSSISRFNSGFYLSIMFGLPGAAFGVYRGIIHDDKRKILA
LLFPGAFAAFFTGITEPLEFLFVFTAPLLYFVHAIYTGFALLIANILDISVGMTFSAGFLDFVMFGILQGHDKTNWLYLL
PLGLLFFALYYFTFKWVYNYFDFQILGVGEPFFAGSEGEVEGMGIAHLIVQGLGGLDNIQEFGVVSTNLNFVVFSPELRF
EDFLKKTGALNIVTVGNTIQIDYGTNVYYIKQAIENYSSKSLFKASVIVASENIRQGIKAYIDMKEDDKREKQGATGKLY
KLNKDDRD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=511, Percent_Identity=33.4637964774951, Blast_Score=250, Evalue=2e-67,
Organism=Escherichia coli, GI1787343, Length=505, Percent_Identity=30.6930693069307, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786894, Length=517, Percent_Identity=30.7543520309478, Blast_Score=174, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 63138; Mature: 63138

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFSVIGFLKILKFANLQKFSSAVRLPISVTTIFSLMLGIGSAFLNPSNLFYIDNAVFK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
LILGLIKSISNIVILNIPLFFVIGIAVVVARVQKGTAALLGLVGYLIFNVTENYFLGVFS
HHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAESDLMSSVGQVKVLGIQTLNTGILGGLSVGLLVGYLHNRFCNIELPGPFDIFSGIRF
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
VSMVIFPFCILLGVLFFLIWPYFNELITSFGFFIAKLDYYGSFFYGFLNRILIPLGLHSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LTFPFNFTSLGGSEIINDQVVGGIQNIFYAQLSDPYLTKFSSSISRFNSGFYLSIMFGLP
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCC
GAAFGVYRGIIHDDKRKILALLFPGAFAAFFTGITEPLEFLFVFTAPLLYFVHAIYTGFA
CHHHHHHHHHHCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIANILDISVGMTFSAGFLDFVMFGILQGHDKTNWLYLLPLGLLFFALYYFTFKWVYNY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
FDFQILGVGEPFFAGSEGEVEGMGIAHLIVQGLGGLDNIQEFGVVSTNLNFVVFSPELRF
HCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCEEEECCEEEEECCCCCH
EDFLKKTGALNIVTVGNTIQIDYGTNVYYIKQAIENYSSKSLFKASVIVASENIRQGIKA
HHHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCCCHHHHHHEEEECHHHHHHHHH
YIDMKEDDKREKQGATGKLYKLNKDDRD
HHCCCCCHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure
MERFSVIGFLKILKFANLQKFSSAVRLPISVTTIFSLMLGIGSAFLNPSNLFYIDNAVFK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHH
LILGLIKSISNIVILNIPLFFVIGIAVVVARVQKGTAALLGLVGYLIFNVTENYFLGVFS
HHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAESDLMSSVGQVKVLGIQTLNTGILGGLSVGLLVGYLHNRFCNIELPGPFDIFSGIRF
HHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
VSMVIFPFCILLGVLFFLIWPYFNELITSFGFFIAKLDYYGSFFYGFLNRILIPLGLHSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LTFPFNFTSLGGSEIINDQVVGGIQNIFYAQLSDPYLTKFSSSISRFNSGFYLSIMFGLP
HCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEEECCC
GAAFGVYRGIIHDDKRKILALLFPGAFAAFFTGITEPLEFLFVFTAPLLYFVHAIYTGFA
CHHHHHHHHHHCCCCHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIANILDISVGMTFSAGFLDFVMFGILQGHDKTNWLYLLPLGLLFFALYYFTFKWVYNY
HHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
FDFQILGVGEPFFAGSEGEVEGMGIAHLIVQGLGGLDNIQEFGVVSTNLNFVVFSPELRF
HCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCCEEEECCEEEEECCCCCH
EDFLKKTGALNIVTVGNTIQIDYGTNVYYIKQAIENYSSKSLFKASVIVASENIRQGIKA
HHHHHHCCCEEEEEECCEEEEECCCCCHHHHHHHHCCCCCHHHHHHEEEECHHHHHHHHH
YIDMKEDDKREKQGATGKLYKLNKDDRD
HHCCCCCHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]